Abstract：
:The capsule of the muscle spindle from the anterior and posterior latissimus dorsi muscles of the adult domestic chicken has been studied with the electron microscope. As in other species, two distinct portions of the spindle capsule are distinguished: an outer capsule and an inner capsule. The outer capsule is structurally similar to and continuous with the perineural epithelium. Outer capsule cells are noted by the abundance of pinocytotic vesicles and a network of 6-7-nm microfilaments. The disposition of these microfilaments is circumferential with respect to the longitudinal axis of the spindle. It is proposed that they may provide a contractile mechanism for the capsule which may be related to the over-all functioning of the spindle during movements of the muscle. The inner capsule is composed of a contiguous network of cells possessing long cytoplasmic processes which envelop the intrafusal fibers and their nerve endings in sensory equatorial regions of the spindle. These cells may elaborate the fibrillar and amorphous extracellular material found in periaxial spindle space. They also possess modified cilia with a "9+0" microtubular pattern. It is suggested that these cilia may behave as sensory transducers, relating fluid changes in the periaxial space to the intrafusal fiber nerve endings. Capillaries of the non-fenestrated variety commonly traverse the outer and inner portions of the capsule and are usually completely surrounded by tenuous overlapping processes of inner capsule cells. These findings suggest that the spindle capsule plays a role as a metabolically-active diffusion barrier to the entrance of substances from the external milieu.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Ovalle WKdoi
10.1007/BF00220126keywords:
subject
Has Abstractpub_date
1976-02-25 00:00:00pages
285-98issue
3eissn
0302-766Xissn
1432-0878journal_volume
166pub_type
杂志文章abstract：:Placenta-derived stem cells (PDSCs) have gained interest as an alternative source of stem cells for regenerative medicine because of their potential for self-renewal and differentiation and their immunomodulatory properties. Although many studies have characterized various PDSCs biologically, the properties of the sel...
journal_title：Cell and tissue research
pub_type： 临床试验,杂志文章
doi：10.1007/s00441-011-1249-8
更新日期：2011-10-01 00:00:00
abstract：:Fibroblast growth factors (Fgfs) are proteins with diverse functions in development, repair, and metabolism. The human Fgf gene family with 22 members can be classified into three groups, canonical, intracellular, and hormone-like Fgf genes. In contrast to canonical and intracellular Fgfs identified in invertebrates a...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-010-1024-2
更新日期：2010-10-01 00:00:00
abstract：:Previous studies have identified Dogiel type II neurons with cell bodies in the myenteric plexus of guinea-pig ileum to be intrinsic primary afferent neurons. These neurons also have distinctive electrophysiological characteristics (they are AH neurons) and 82-84% are immunoreactive for calbindin. They are the only ca...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100395
更新日期：2001-07-01 00:00:00
abstract：:An antiserum against the octapeptide Pea-CAH-I, a member of the adipokinetic hormone/red pigment-concentrating hormone family, has been produced for immunocytochemical staining in insects and various other invertebrate species. The anti-Pea-CAH-I serum stains the glandular corpora cardiaca cells of those insect specie...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050601
更新日期：1996-06-01 00:00:00
abstract：:To determine whether lipid-secreting cells have cytosolic Ca2+ concentration ([Ca2+]c)-related secretory mechanisms, morphological changes and intracellular calcium dynamics of Harderian glands of guinea pigs stimulated by secretagogue were studied by electron microscopy and Fura-2/AM digital image analysis. Control g...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00327979
更新日期：1993-10-01 00:00:00
abstract：:Connective tissue microfibrils were observed in tissues prepared with methods believed to minimize the loss of tissue components. The eyes of C57BL/6J mice were fixed with glutaraldehyde followed by either freeze substitution, or embedding in glycol methacrylate, a water-miscible embedding medium, after limited or no ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318486
更新日期：1995-02-01 00:00:00
abstract：:Transgenic rats for the murine Ren-2 gene display high blood pressure, low circulating levels of angiotensin II, and high renin content in the adrenal glands. Moreover, transgenic rats possess an increased aldosterone secretion (maximal from 6 to 18 weeks of age), paralleling the development of hypertension. To invest...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00305774
更新日期：1994-10-01 00:00:00
abstract：:Four months after the selective ablation of inner hair cells by carboplatin, the interdental cell epithelium exhibited dilated intercellular spaces and cytosolic vacuoles not seen in controls. In addition, the wide, often electron-lucent phalanges observed in the interdental cells of the normal chinchilla collapsed in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000253
更新日期：2000-10-01 00:00:00
abstract：:Ossification of calvariae from day-21 rat fetuses was reinvestigated by electron microscopy using different fixation techniques (glutaraldehyde/OsO4, tannic acid, ruthenium red, K-pyroantimonate). An osteoid layer with scattered mineral deposits was found at the mineralization front. Directly beyond this layer, a shee...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318693
更新日期：1992-01-01 00:00:00
abstract：:CD4+CD25+(high) regulatory T cells (Tregs) play a pivotal role in the control of the immune response. A growing body of evidence suggests the reduced function of these cells in autoimmune diseases, including type 1 diabetes (T1D). Restoration of their function can potentially delay further disease development. In the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0900-0
更新日期：2010-03-01 00:00:00
abstract：:The purpose of this study was to determine the cellular distribution and degradation in rat liver following intravenous injection of superparamagnetic iron oxide nanoparticles used for magnetic resonance imaging (NC100150 Injection). Relaxometric and spectrophotometric methods were used to determine the concentration ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0884-8
更新日期：2004-06-01 00:00:00
abstract：:Using techniques for enhanced microtubular preservation (albumin pretreatment of Gray) occipital and pyriform cortices of rats were studied by electron microscopy at various stages of development. A close structural relationship was seen between microtubules (mts), focal membrane densities, synaptic vesicles, and pres...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215777
更新日期：1983-01-01 00:00:00
abstract：:The cumulus and membrana granulosa of non-atretic ovarian follicles from primordial up to a stage shortly before ovulation were studied by electron microscopy. The follicular cells of primordial follicles were undifferentiated and rested on a thick basal lamina. In secondary follicles the endoplasmic reticulum had pro...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220436
更新日期：1979-11-01 00:00:00
abstract：:An immunohistochemical staining technique with the D2-40 antibody was undertaken to examine the functional and morphological features of lymphatic networks in tissue sections and whole-mount preparations of normal nasal mucosa and ethmoid sinus mucosa. In normal nasal mucosa, most lymphatic vessels were found in the s...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0337-7
更新日期：2007-03-01 00:00:00
abstract：:Intracellular insulin-binding sites were directly traced in fixed monolayer cultures of a variety of cell types with the use of two fluorescent derivatives of insulin, viz. fluorescein isothiocyanate (FITC)-labelled and tetramethyl rhodamine isothiocyanate (TMRITC)-labelled insulin. Both derivatives retained the prope...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00232150
更新日期：1980-01-01 00:00:00
abstract：:A tumor model system of clones of myeloproliferative sarcoma virus (MPV)-transformed rat fibroblasts (NRK) with different growth properties and metastatic potential was studied. The relationship between metastatic behavior and composition of carbohydrate-binding proteins (lectins) was analyzed by affinity chromatograp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215191
更新日期：1986-01-01 00:00:00
abstract：:Distribution of microtubules and other cytoskeletal filaments in growing skeletal muscle cells (myotubes) was studied in vitro by fluorescence microscopy using fluorescin-labeled antibodies and phalloidin, a specific antiactin drug. In the distal elongating tips of myotubes, microtubules were the major cytoskeletal el...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214368
更新日期：1988-05-01 00:00:00
abstract：:Using anti-carp-gonadotropic-gamma-globulin, the indirect immunofluorescence technique was applied to sections of the pituitary of 12 teleost species. From the investigated species, the Poeciliinae, and especially the black molly, showed a distinct localization of fluorescent cells in the mesoadenohypophysis. Strong f...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224328
更新日期：1976-03-16 00:00:00
abstract：:Agitation of villi evokes reflexes that affect the motility of the guinea-pig small intestine. NK1 receptor endocytosis was used to investigate the possible involvement of tachykinins acting on neuronal NK1 receptors in these reflexes. Segments of guinea-pig ileum were incubated at 37 degrees C in Krebs physiological ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051032
更新日期：1998-04-01 00:00:00
abstract：:Male germ cells of the greater bandicoot rat, Bandicota indica, have recently been categorized into 12 spermiogenic steps based upon the morphological appearance of the acrosome and nucleus and the cell shape. In the present study, we have found that, in the Golgi and cap phases, round spermatid nuclei contain 10-nm t...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0668-7
更新日期：2008-10-01 00:00:00
abstract：:NCS-1 (neuronal calcium sensor) is a recently characterized member of a highly conserved neuron-specific family of calcium-binding proteins, which also includes frequenin and recoverin. The cellular and subcellular distributions of NCS-1 in the rat nervous system were investigated using light- and electron-microscopic...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051246
更新日期：1999-03-01 00:00:00
abstract：:The fine structural organization of a cortical filament layer in normal locomoting Amoeba proteus was demonstrated using improved fixation and embedding techniques. Best results were obtained after application of PIPES-buffered glutaraldehyde in connection with substances known to prevent the depolymerization of F-act...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215699
更新日期：1982-01-01 00:00:00
abstract：:Iron loading of hepatocytes was followed through the stages (1-7) of metamorphosis in lamprey (Petromyzon marinus L.) using light- and electron-microscopic histochemistry. Iron is present in ferric and ferrous forms in the hepatocytes of larval lampreys in levels that can only be detected in the electron microscope. D...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217405
更新日期：1983-01-01 00:00:00
abstract：:Immunoreactivity for calcitonin gene-related peptide is demonstrated for the first time in neuroepithelial bodies in the lung of newborn cats after Bouin fixation and embedding in paraffin. The intense staining clearly identifies these bodies at the level of bronchioli and alveoli. Occasionally, single neuroepithelial...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215517
更新日期：1987-08-01 00:00:00
abstract：:Galanin immunoreactivity was observed in nerve cell bodies and nerve fibres, but not in enteroendocrine cells, in the small intestine of the guinea-pig. Nerve terminals were found in the myenteric plexus, in the circular muscle, in submucous ganglia, around submucous arterioles, and in the mucosa. Lesion studies showe...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218954
更新日期：1987-12-01 00:00:00
abstract：:Ultrastructural aspects of hypertrophic chondrocytes in hamster and mouse epiphysial cartilage were examined in relation to their metabolic activities. With the hypertrophic change, cytoplasmic vacuolization proceeded leaving the partially intact endoplasmic reticulum (ER). In the hypertrophic cells, cytoplasmic hyalu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900082
更新日期：1999-11-01 00:00:00
abstract：:Many efforts have been made to improve the diagnostic tools used to identify and to estimate the progress of ganglion cell and nerve fibre degeneration in glaucoma. Imaging by optical coherence tomography and measurements of the dimensions of the optic nerve head and the nerve fibre layer in central retinal areas is c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1602-1
更新日期：2013-08-01 00:00:00
abstract：:Overexpression of type XIII collagen molecules with an 83-amino-acid residue in-frame deletion of part of the ectodomain leads to fetal lethality in Col13a1COL2del transgenic mice. We characterize here the functional disturbances in the cardiovascular system of mouse fetuses overexpressing mutant type XIII collagen. D...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-008-0617-5
更新日期：2008-07-01 00:00:00
abstract：:Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome and characterized by the degradation of articular cartilage and synovial inflammation. Here, we isolated bone marrow mesenchymal stem cells (BMSCs) from rat's bone marrow and BMSC-derived exosome (BMSCs-Exo) from BMSCs successf...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03319-1
更新日期：2021-01-06 00:00:00
abstract：:In an attempt to identify pancreatic islet cells emitting formaldehyde-induced fluorescence (FIF), the pancreatic islets of the domestic fowl were studied by combined fluorescence, ultrastructural, silver-impregnation and immunohistochemical methods in the same section or in consecutive semi-thin and ultra-thin sectio...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217141
更新日期：1984-01-01 00:00:00
