Abstract：
:Electron-microscopic evidence indicates that during conditions of high hormone demand such as lactation there is a dramatic reduction in the number of fine glial processes which are normally interposed between magnocellular neuroendocrine cell somata in the supraoptic nucleus (SON). The purpose of this study was to corroborate these data at the light-microscopic level and to gain some insight into what underlying events might accompany these apparent morphological changes. The distribution of the glial fibrillary acidic protein (GFAP), an intermediate filament component of the astrocytic cytoskeleton, was visualized in lactating or estrous rats using peroxidase-antiperoxidae immunocytochemistry. Computerized image analysis was employed to determine and compare the staining distributions of this protein for the two groups of rats. Statistical analysis revealed a redistribution of GFAP immunostaining in the SONs of lactating animals as compared to controls. No differences in staining were found in a control area dorsolateral to SON. The pattern of change was to a less dense, more homogeneous distribution of GFAP in lactating rats, a change which could be interpreted as reflective of a reduction in the number of densely staining glial processes.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Salm AK,Smithson KG,Hatton GIdoi
10.1007/BF00225557subject
Has Abstractpub_date
1985-01-01 00:00:00pages
9-15issue
1eissn
0302-766Xissn
1432-0878journal_volume
242pub_type
杂志文章abstract：:The neuropeptide content of nerve fibers associated with submucosal arteries in the small intestine of guinea pigs was studied in whole-mount preparations using immunohistochemical methods. Tissues were obtained from normal animals or animals in which the small intestine had been extrinsically denervated. In normal an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219756
更新日期：1988-09-01 00:00:00
abstract：:Three sites of somatostatin-synthesizing perikarya, or a related antigen, were determined by immunofluorescence in the hypothalamus of the tadpole, Alytes obstetricans (Amphibia, Anura). Two sites of neurosecretory perikarya were localized in the preoptic nuclei of the anterior hypothalamus; the axons extended either ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224373
更新日期：1978-02-24 00:00:00
abstract：:The retinal projections in adult and juvenile guitar fish (Rhinobatos productus) were determined with the aid of the Nauta-Fink-Heimer techniques. The visual system was found to be more extensive and more differentiated than in any other elasmobranch studied to date. Massive projections exist to the dorsal and ventral...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00232768
更新日期：1980-01-01 00:00:00
abstract：:The ciliary axoneme in photoreceptors from the retina of Xenopus laevis was examined by immunofluorescent staining of tubulin throughout the light/dark cycle. The immunofluorescent axoneme extended along only part of the length of rod outer segments but the entire length of cone outer segments. Both the cone axoneme a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050632
更新日期：1996-07-01 00:00:00
abstract：:Tissue lectins appear to be involved in a broad range of physiological processes, as reflected for the members of the family of galectins by referring to them as adhesion/growth-regulatory effectors. In order to clarify the significance of galectin presence, key challenges are to define their binding partners and the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2931-x
更新日期：2019-03-01 00:00:00
abstract：:The localization of neuropeptide Y (NPY) and atrial natriuretic peptide (ANP) in the endothelial cells of human umbilical blood vessels was studied using the pre-embedding peroxidase-antiperoxidase (PAP) technique for electron microscopy and avidin-biotin-complex (ABC) immunostaining for endothelial cells cultured fro...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00323584
更新日期：1993-04-01 00:00:00
abstract：:The occurrence and distribution of peptidergic nerves in the guinea pig uterus was studied by means of immunocytochemistry using numerous neuropeptide anti-sera. Neuropeptide Y (NPY)-immunoreactive (IR) nerves were the most abundant, whereas substance P (SP)-, calcitonin gene-related peptide (CGRP)-, and neurokinin A ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226501
更新日期：1988-01-01 00:00:00
abstract：:Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome and characterized by the degradation of articular cartilage and synovial inflammation. Here, we isolated bone marrow mesenchymal stem cells (BMSCs) from rat's bone marrow and BMSC-derived exosome (BMSCs-Exo) from BMSCs successf...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03319-1
更新日期：2021-01-06 00:00:00
abstract：:A synthetic 17-mer peptide corresponding to an unique sequence in the amino-terminal region of human creatine kinase B was used to raise a new and highly B-subunit-specific monoclonal antibody, CK-BYK/21E10. We show here that the monoclonal antibody is suitable for immunohistochemistry of unfixed frozen sections as we...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00307817
更新日期：1995-05-01 00:00:00
abstract：:In model experiments with the use of horseradish peroxidase (HRP), two pathways of transport of substances to the adenohypophysis were studied, as well as the distribution of the tracer in the latter organ. The first pathway allows the tracer to penetrate from the intercellular milieu of the median eminence below the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214248
更新日期：1984-01-01 00:00:00
abstract：:The excretory system of Macrobiotus richtersi consists of one dorsal and two lateral components and shows a high degree of structural complexity. In each of these a tricellular external lobe and a column can be distinguished, the two parts being connected distally. The surface of the lobe cells is increased by deep ba...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00239339
更新日期：1980-01-01 00:00:00
abstract：:The muscle cells of the ventricle, the branchial heart and the branchial heart appendages of Rossia macrosoma (Delle Chiaje) are studied. The ventricle myocardium has three muscle layers, while the other two organs exhibited a loose arrangement of muscle cells. The muscle cells of the ventricle, the branchial heart an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：
更新日期：1977-12-13 00:00:00
abstract：:The projections of ocellar fibres within the brain and thorax of the honey bee, Apis mellifera, were established using a modified cobalt sulphide technique, supplemented by serial sectioning of the brain for the light microscope. The results are: 5 large fibres in each lateral nerve and 12 in the median nerve have wid...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00231405
更新日期：1977-01-24 00:00:00
abstract：:The chemical nature of the thickened plasma membrane of cornified cells in stratified squamous epithelium was investigated in comparison with that in noncornified epithelium. Localizations of transglutaminase, molecular weight 92,000 daltons, and detection of epidermal cysteine proteinase inhibitor were effected with ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215516
更新日期：1987-08-01 00:00:00
abstract：:Kisspeptin is a hypothalamic neuropeptide, which acts directly on gonadotropin-releasing hormone (GnRH)-secreting neurons via its cognate receptor (GPR54 or Kiss-R) to stimulate GnRH secretion in mammals. In non-mammalian vertebrates, there are multiple kisspeptins (Kiss1 and Kiss2) and Kiss-R types. Recent gene knock...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03089-5
更新日期：2020-02-01 00:00:00
abstract：:We have developed a primary cell culture system of antennal mechanoreceptor neurons from early-stage pupal sphinx moth Manduca sexta. Dissociated neurons from the moth antennae differentiated, grew and survived for several weeks in a conditioned culture medium. Bipolar neurons with soma diameters of 10-25 microns from...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051358
更新日期：1999-08-01 00:00:00
abstract：:Triad density relative to sarcomeres, size of T-system tubules, sarcomere length, muscle fiber diameter in native and fixed states, and size of myofibrils were measured in four straited muscle fiber types in Atlantic hagfishes (Myxine glutinosa, L.) of different sizes. Traids occur at A/I-injunctions in all fiber type...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223227
更新日期：1975-01-01 00:00:00
abstract：:The papillary muscle of the cat heart's right ventricle has not been studied previously with quantitative ultrastructural techniques despite its wide use for functional studies. This tissue was perfusion-fixed, processed for electron microscopy, and morphometric techniques were used to assess the ultrastructural chara...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216200
更新日期：1983-01-01 00:00:00
abstract：:The immunological identity of a uteroglobin-like protein, occurring in respiratory tract secretions and tissue, with uteroglobin from rabbit endometrial secretion is demonstrated. A uteroglobin-like antigen has been localized in bronchial epithelial cells and in bronchioles by immunofluorescence. This secretory protei...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210033
更新日期：1978-06-26 00:00:00
abstract：:Cortisone-treated Buffalo rats have been parabiosed with untreated controls of the same age. The optical and electron microscopy, including histochemistry, of costal cartilage of these rats has been compared with that in single cortisone treated rats, single controls, and control parabiosed with control rats, at 14 an...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223122
更新日期：1978-05-18 00:00:00
abstract：:Glial cell line-derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and identified as a neurotrophic factor with the ability to promote dopamine uptake within midbrain dopaminergic neurons. Since its discover...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-020-03287-6
更新日期：2020-10-01 00:00:00
abstract：:We have previously shown that the chromogranin A (CgA)-derived peptide catestatin (CST: hCgA352-372) inhibits nicotine-induced secretion of catecholamines from the adrenal medulla and chromaffin cells. In the present study, we seek to determine whether CST regulates dense core (DC) vesicle (DCV) quanta (catecholamine ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2956-1
更新日期：2019-04-01 00:00:00
abstract：:Activities of the H+, K(+)-ATPase and the Na+, K+, ATPase have been localized in the morphologically heterogeneous oxyntic cell lineage of adult bovine abomasal mucosa, by means of K(+)-dependent paranitrophenylphosphatase (K(+)-pNPPase) histochemistry. At the light- and electron-microscopic level, only members of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050583
更新日期：1996-05-01 00:00:00
abstract：:Changes in the ultrastructure of the toad epidermis during the moulting cycle are described on the basis of 17 skin preparations fixed in consecutive phases of the cycle. Our previous light microscopical findings that morphological changes are mainly restricted to a short period prior to and after shedding are confirm...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221703
更新日期：1975-06-24 00:00:00
abstract：:Estradiol injections increase serum level of calcium, amino acid, glucose, protein, ammonia and creatinine in immature Epinephelus akaara, and also increase levels of total lipid, cholesterol, phospholipid and esterified fatty acids. Hepatic protein, glycogen and lipid concentrations also rise after estradiol treatmen...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217235
更新日期：1984-01-01 00:00:00
abstract：:Mesenchymal stromal cells (MSCs), especially those lying close to cartilage defects, are an important cell source for cartilage regeneration. We hypothesize that a larger number of MSCs might become available, if the bone marrow in the immediate vicinity of the subchondral bone is stimulated for MSCs in advance of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-1020-6
更新日期：2010-09-01 00:00:00
abstract：:Neuronal differentiation is characterized by stereotypical sequences of membrane channel and receptor acquisition. This is regulated by the coordinated interactions of a variety of developmental mechanisms, one of which is the control by steroid hormones. We have used the metamorphosis of the holometabolous insect, Ma...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0175-7
更新日期：2006-07-01 00:00:00
abstract：:Previous neurohistological studies have been extended to include the structures contained solely or mainly within the junctional esophageal segment which may play an important role in the sphincter mechanism. The main findings were: 1) a progressive cranio-caudal thickening of the muscularis mucosae; 2) a conspicuous ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215998
更新日期：1976-05-26 00:00:00
abstract：:The present immunocytochemical study concerns the distribution of four neuropeptides, FMRF-amide, vasotocin, leu-enkephalin and neurotensin, and of the bioamine serotonin in the plerocercoid larva of Diphyllobothrium dendriticum. Anti-FMRF-amide and vasotocin-reactivity occurs in perikarya and nerve fibres in the CNS ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222332
更新日期：1985-01-01 00:00:00
abstract：:A study of the organisation of the locust dorsal ocellus shows that the structure is designed to provide the maximum possible effective aperture. The condenser-like cuticular lens and the dispersal of the rhabdome over a large proportion of the circumferential area of the retinula cells increases the light gathering p...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234742
更新日期：1979-02-28 00:00:00
