Heterogeneity and migration-related zonation of K(+)-ATPase activities in the oxyntic cell lineage of adult cattle.


:Activities of the H+, K(+)-ATPase and the Na+, K+, ATPase have been localized in the morphologically heterogeneous oxyntic cell lineage of adult bovine abomasal mucosa, by means of K(+)-dependent paranitrophenylphosphatase (K(+)-pNPPase) histochemistry. At the light- and electron-microscopic level, only members of the mature oxyntic cell population within the oxyntic glandular base exhibit strong enzyme activity. Superficial oxyntic cells of the proximal isthmus and deep pit, arising from the upward migration of precursor cells and commonly supposed to have a high capacity of secreting acid, show weak or no enzyme activity. This is also true of the immature and pre-oxyntic cells of the generative zone. Global enzyme activity varies among the mature glandular oxyntic cell population. Ultracytochemically, strong H+, K(+)-ATPase (ouabain-insensitive K(+)-pNPPase) activity is associated with the apical plasmalemmal and expanded canalicular membrane in contrast to Na+, K(+)-ATPase (ouabain-sensitive K(+)-pNPPase) activity, which is localized on the basolateral plasmalemmal folds. In both cases, histochemical deposition is confined to the cytoplasmic aspect of the membranes. These results suggest a functional zonation and position-dependent heterogeneity of the oxyntic cell lineage related to the bidirectional mode of migration of pre-oxyntic cells during physiological cell renewal. Functional heterogeneity within the mature glandular oxyntic cell population is in accordance with the continuous mode of gastric acid secretion in cattle.


Cell Tissue Res


Cell and tissue research


Kressin M




Has Abstract


1996-05-01 00:00:00












  • Evolution and ultrastructure of the bovine spermatogonia precursor cell line.

    abstract::The spermatogonial stem cell line in prepubertal and adult bovine testis was studied by electron microscopy and protein gene product 9.5 immunohistochemistry. Three successive spermatogonia precursor cell configurations were observed. Small basal stem cells were found to possess a spherical shape and nuclei with two t...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Wrobel KH,Bickel D,Kujat R,Schimmel M

    更新日期:1995-08-01 00:00:00

  • Autonomic innervation of the ocular choroid membrane in the chicken: a fluorescence-histochemical and electron-microscopic study.

    abstract::The distribution pattern of adrenergic fibres innervating the ocular choroid membrane of the chicken was studied by means of fluorescence and electron microscopy. In addition, the origin of these fibres was investigated after superior cervical ganglionectomy. Adrenergic axons reach the choroid, partly forming the peri...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Guglielmone R,Cantino D

    更新日期:1982-01-01 00:00:00

  • Ultrastructural alterations of the pancreatic D cell in the domestic fowl following vagotomy.

    abstract::In an attempt to determine the neural control of pancreatic D cells, the pancreatic islets of the domestic fowl were examined electron microscopically from 1 to 28 days after abdominal vagotomy. Exocytotic release of many secretory granules from D cells occurred one day after vagotomy. Rough endoplasmic reticulum deve...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Watanabe T,Fujioka T

    更新日期:1980-01-01 00:00:00

  • The influence of luteinizing hormone-releasing hormone (LHRH) on the process of protein and/or peptide secretion characterized by the formation of granular vesicles in mammalian pinealocytes. Comparative in vitro study.

    abstract::In the present study, the effect of LHRH on the process of protein and/or peptide secretion characterized by the formation of granular vesicles has been studied by means of an in vitro system in the pinealocytes of three different species of rodents. LHRH has a strong influence on the activity of this process. However...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Haldar-Misra C,Pévet P

    更新日期:1983-01-01 00:00:00

  • Bone marrow-derived versus adipose-derived stem cells in wound healing: value and route of administration.

    abstract::The stem cells with their distinct ability of self-renewal and differentiation are considered an innovation in wound healing. However, there is lack of studies comparing the differential effect of the type and administration route of stem cells in the wound healing context. Thus, the current study has been designed to...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Aboulhoda BE,Abd El Fattah S

    更新日期:2018-11-01 00:00:00

  • FGF2 and dexamethasone increase the production of hyaluronan in two-dimensional culture of elastic cartilage-derived cells: in vitro analyses and in vivo cartilage formation.

    abstract::Elastic cartilage-derived cells cultured two-dimensionally with FGF2 and corticosteroid produce gel-type masses that become mature cartilage when injected into a subcutaneous pocket. This unique method has previously been clinically applied for treatments of nasal augmentation. However, the components of the gel-type ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Yokoyama A,Muneta T,Nimura A,Koga H,Mochizuki T,Hata Y,Sekiya I

    更新日期:2007-09-01 00:00:00

  • Dislocated type-A spermatogonia in human seminiferous tubules.

    abstract::Type-A spermatogonia can be found in different locations throughout the germinal epithelium of human seminiferous tubules. Generally they represent the population of germ cells adjacent to the basal lamina, but under special conditions they may be located in the adluminal compartment. This aberrant location is found n...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Holstein AF,Bustos-Obregón E,Hartmann M

    更新日期:1984-01-01 00:00:00

  • Autophagy in periodontal ligament fibroblasts under biomechanical loading.

    abstract::Autophagy (cellular self-consumption) is an adaptive stress response and an important aspect of adaption to mechanical loading. If mechanical forces are associated with autophagy regulation in periodontal ligament (PDL) fibroblasts is still unknown. The aim of this study was to analyze the influence of force magnitude...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Memmert S,Damanaki A,Weykopf B,Rath-Deschner B,Nokhbehsaim M,Götz W,Gölz L,Till A,Deschner J,Jäger A

    更新日期:2019-12-01 00:00:00

  • Radiation effects on neural precursor cells in the dentate gyrus.

    abstract::Ionizing irradiation is an effective treatment for intracranial tumors but is limited by the potential adverse effects induced in surrounding normal brain. These effects can include cognitive impairments, and whereas the pathogenesis of such injury has not yet been definitively established, it may involve injury to th...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Andres-Mach M,Rola R,Fike JR

    更新日期:2008-01-01 00:00:00

  • Localisation of substance P-like immunoreactivity in the ciliary ganglia of monkey (Macaca fascicularis) and cat: a light- and electron-microscopic study.

    abstract::The present study describes substance P-like immunoreactivity in the ciliary ganglia of monkey (Macaca fascicularis) and cat. About 60% of neurons in the monkey ciliary ganglion and 40% in the cat ciliary ganglion were substance P-like immunoreactive, ranging from faint to moderate staining. Substance P-like immunorea...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Zhang YL,Tan CK,Wong WC

    更新日期:1994-04-01 00:00:00

  • Cocaine- and amphetamine-related transcript peptide and somatostatin in rat intracardiac ganglia.

    abstract::The distribution of somatostatin and cocaine and amphetamine-regulated transcript (CART) was investigated in rat intracardiac ganglia. Somatostatin immunoreactivity was only present in nerve terminals, always colocalised with choline acetyltransferase immunoreactivity, surrounding approximately 10% of intracardiac neu...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Richardson RJ,Grkovic I,Anderson CR

    更新日期:2006-04-01 00:00:00

  • A new type of gap junction in the phylum Brachiopoda.

    abstract::Gap junctions in the phylum Brachiopoda are shown to be of the P type as has been previously reported in invertebrates only in molluscs and possibly bryozoans. However, the mollusc gap junctions appear identical to vertebrae gap junctions in the fracture face on which particles remain, in particle spacing and in parti...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Flower NE,Green CR

    更新日期:1982-01-01 00:00:00

  • Molecular and cellular detection of expression of vitellogenin and zona radiata protein in liver and skin of juvenile salmon (Salmo salar) exposed to nonylphenol.

    abstract::In developing bioassays for estrogenic effects, vitellogenin (Vtg) induction and zona radiata protein (Zr-protein) induction in males and juveniles of oviparous vertebrates have been used as sensitive biomarkers for estrogenicity. Nonylphenol (NP) produces similar and parallel expression patterns of Vtg and Zr-protein...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Arukwe A,Røe K

    更新日期:2008-03-01 00:00:00

  • Elevated gene expression of MMP-1, MMP-10, and TIMP-1 reveal changes of molecules involved in turn-over of extracellular matrix in cyclosporine-induced gingival overgrowth.

    abstract::In humans, pathogenesis in cyclosporine A (CsA)-induced gingival overgrowth (GO) includes the accumulation of extracellular matrix (ECM) constituents, viz., collagen type-1 and type-3 and proteoglycans, in subgingival connective tissue. However, whether this increase is associated with alterations of molecules pivotal...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Dannewitz B,Edrich C,Tomakidi P,Kohl A,Gabbert O,Eickholz P,Steinberg T

    更新日期:2006-09-01 00:00:00

  • Cellular interconnections in the young mouse ovary. Freeze-fracture study.

    abstract::Intercellular junctions in the young mouse ovary were examined by electron microscopy utilizing freeze-fracture and thin-sectioning techniques. Projections from the granulosa cells adjacent to the oocyte (GI) traverse the zona pellucida and form small gap junctions on the oocyte surface. On the P-face of these cells, ...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Toshimori K,Oura C

    更新日期:1982-01-01 00:00:00

  • Connexins and gap junctions in the inner ear--it's not just about K⁺ recycling.

    abstract::Normal development, function and repair of the sensory epithelia in the inner ear are all dependent on gap junctional intercellular communication. Mutations in the connexin genes GJB2 and GJB6 (encoding CX26 and CX30) result in syndromic and non-syndromic deafness via various mechanisms. Clinical vestibular defects, h...

    journal_title:Cell and tissue research

    pub_type: 杂志文章,评审


    authors: Jagger DJ,Forge A

    更新日期:2015-06-01 00:00:00

  • Vascular permeability (problem of the blood-brain barrier) in the pineal organ of the rainbow trout, Salmo gairdneri.

    abstract::The problem of the blood-brain barrier in the pineal organ of the rainbow trout, Salmo gairdneri, was investigated following intraperitoneal or intracardial injections of several tracers and dyes with different molecular weights. As demonstrated at the light-microscopic level, repeated injections of trypan blue or hor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Omura Y,Korf HW,Oksche A

    更新日期:1985-01-01 00:00:00

  • Human and rodent bone marrow mesenchymal stem cells that express primitive stem cell markers can be directly enriched by using the CD49a molecule.

    abstract::Bone marrow (BM) from human and rodent species contains a population of multipotential cells referred to as mesenchymal stem cells (MSCs). Currently, MSCs are isolated indirectly by using a culture step and then the generation of fibroblast colony-forming units (CFU-fs). Unprocessed or native BM MSCs have not yet been...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Gindraux F,Selmani Z,Obert L,Davani S,Tiberghien P,Hervé P,Deschaseaux F

    更新日期:2007-03-01 00:00:00

  • A second cell type in Stannius bodies of two euryhaline telecost species.

    abstract::In the corpuscles of Stannius of sticklebacks and eels two cell types are described of presumably endocrine nature. The predominating type, comparable to the cells observed in other species, responds to variation in calcium content of the medium and possibly produces a hypocalcemic hormone. The second cell type is unr...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Bonga SE,Greven JA

    更新日期:1975-06-09 00:00:00

  • Proliferative capacity of enterochromaffin cells in guinea-pigs with experimental ileitis.

    abstract::Enterochromaffin (EC) cells regulate gut motility and secretion in response to luminal stimuli, via the release of serotonin (5-HT). Inflammatory bowel disease and other gastrointestinal disorders are associated with increased numbers of EC cells and 5-HT availability. Our aim was to determine whether proliferation of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: O'Hara JR,Sharkey KA

    更新日期:2007-09-01 00:00:00

  • Light and electron microscopic studies on the excretory system of Macrobiotus richtersi Murray, 1911 (Eutardigrada).

    abstract::The excretory system of Macrobiotus richtersi consists of one dorsal and two lateral components and shows a high degree of structural complexity. In each of these a tricellular external lobe and a column can be distinguished, the two parts being connected distally. The surface of the lobe cells is increased by deep ba...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Weglarska B

    更新日期:1980-01-01 00:00:00

  • Immunohistochemical observation of growth-associated protein 43 (GAP-43) in the developing circumvallate papilla of the rat.

    abstract::The distribution and development of growth-associated protein 43 (GAP-43)-like immunoreactivity (-LI) in the rat circumvallate papilla (CVP) were compared to those of protein gene product 9.5 (PGP 9.5)-LI. In the adult, thick GAP-43-like immunoreactive (-IR) structures gathered densely in the subgemmal region. Some of...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Wakisaka S,Daikoku H,Miyawaki Y,Youn SH,Maeda T,Kurisu K

    更新日期:1998-09-01 00:00:00

  • Proliferating cell nuclear antigen (PCNA/cyclin) immunocytochemistry as a labeling index in mouse lung tissues.

    abstract::Proliferating cell nuclear antigen is expressed in cells from late G1 through the S-phase of the cell cycle. Therefore, antibodies directed against this molecule should provide a probe for labeling immunocytochemically the nuclei of proliferating cells. Herein we demonstrate the feasibility and reliability of this tec...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Thaete LG,Ahnen DJ,Malkinson AM

    更新日期:1989-04-01 00:00:00

  • Anatomical organization of the cerebrum of the desert locust Schistocerca gregaria.

    abstract::The desert locust Schistocerca gregaria is a major agricultural pest in North Africa and the Middle East. As such, it has been intensely studied, in particular with respect to population dynamics, sensory processing, feeding behavior flight and locomotor control, migratory behavior, and its neuroendocrine system. Bein...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: von Hadeln J,Althaus V,Häger L,Homberg U

    更新日期:2018-10-01 00:00:00

  • Fine structure and primary sensory projections of sensilla located in the labial-palp pit organ of Helicoverpa armigera (Insecta).

    abstract::The fine structure and primary sensory projections of sensilla located in the labial-palp pit organ of the cotton bollworm Helicoverpa armigera (Insecta, Lepidoptera) are investigated by scanning electron and transmission electron microscopy combined with confocal laser scanning microscopy. The pit organ located on th...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Zhao XC,Tang QB,Berg BG,Liu Y,Wang YR,Yan FM,Wang GR

    更新日期:2013-09-01 00:00:00

  • Characterization of the population of phagocytic cells in thymic cell suspensions. A morphological and cytochemical study.

    abstract::Rat thymic phagocytic cells were characterized in vitro using various light- and electron-microscopical techniques. Thymic cell suspensions were mechanically prepared and enriched for non-lymphoid cells, which were predominantly phagocytic and of three types. Type I showed acid phosphatase (APh) activity in small gran...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Duijvestijn AM,Schutte R,Köhler YG,Korn C,Hoefsmit EC

    更新日期:1983-01-01 00:00:00

  • Similarities and differences in the structure of segmentally homologous neurons that control the hearts of the leech, Hirudo medicinalis.

    abstract::The neural circuit that controls the hearts in the leech comprises an ensemble of synaptically interconnected cardiac motor neurons (HE cells) and cardiac interneurons (HN cells). Both the HE cells and the HN cells constitute segmentally homologous sets. We have investigated the structure of these neurons by iontophor...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Shafer MR,Calabrese RL

    更新日期:1981-01-01 00:00:00

  • The eyes of mesopelagic crustaceans. II. Streetsia challengeri (amphipoda).

    abstract::In Streetsia challengeri left and right eyes have fused and become a single cylindrical photoreceptor, which occupies the basal half of a forward directed head projection. This unusual compound eye consists of approximately 2500 ommatidia, which are arranged in such a way that the animal has almost circumferential vis...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Meyer-Rochow VB

    更新日期:1978-01-17 00:00:00

  • Dominance of parental genomes in embryonic stem cell/fibroblast hybrid cells depends on the ploidy of the somatic partner.

    abstract::Two dozen hybrid clones were produced by fusion of diploid embryonic stem (ES) cells positive for green fluorescent protein (GFP) with tetraploid fibroblasts derived from DD/c and C57BL-I(I)1RK mice. Cytogenetic analysis demonstrated that most cells from these hybrid clones contained near-hexaploid chromosome sets. Ad...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Kruglova AA,Matveeva NM,Gridina MM,Battulin NR,Karpov A,Kiseleva EV,Morozova KN,Serov OL

    更新日期:2010-06-01 00:00:00

  • Ultrastructural immunocytochemical localization of L-glutamate decarboxylase and GABA in rat pancreatic zymogen granules.

    abstract::The ultrastructural immunohistochemical localization of gamma aminobutyric acid (GABA) and its regulating enzymes, L-glutamate decarboxylase (GAD) and gamma aminobutyrate-alpha-ketoglutarate transaminase, was determined utilizing an immunogold post-embedding protocol in pancreatic exocrine tissue. Within the acinar ce...

    journal_title:Cell and tissue research

    pub_type: 杂志文章


    authors: Garry DJ,Garry MG,Sorenson RL

    更新日期:1988-04-01 00:00:00