Abstract：
:Rat thymic phagocytic cells were characterized in vitro using various light- and electron-microscopical techniques. Thymic cell suspensions were mechanically prepared and enriched for non-lymphoid cells, which were predominantly phagocytic and of three types. Type I showed acid phosphatase (APh) activity in small granules dispersed throughout the cytoplasm and were mostly Ia antigen-positive, although the Ia membrane label varied in intensity and distribution among individual cells. Only a few cells had endogenous peroxidase activity. The type-I cells could not be clearly distinguished morphologically from type-II or -III cells, and most likely comprise precursors of both these cell types. Type-II were large pale cells with many slender cell processes. These cells had APh activity centrally positioned, were strongly positive for Ia on the cell membrane and were negative for endogenous peroxidase. The cytoplasm frequently contained Birbeck granules, which unequivocally classifies these cells as the in vitro equivalent of the interdigitating cells present in the medullary area of the thymus in situ. Type-III cells were rounded with a smooth or ruffled cell membrane and contained vacuoles and many phagolysosomes. They were strongly positive for APh which was present throughout the cytoplasm. About 50% of these cells were positive for endogenous peroxidase in a pattern resembling resident macrophages. The cells were negative for Ia antigens. Type-III cells mostly likely represent the macrophages found in the cortical area of the thymus.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Duijvestijn AM,Schutte R,Köhler YG,Korn C,Hoefsmit ECdoi
10.1007/BF00222183subject
Has Abstractpub_date
1983-01-01 00:00:00pages
313-23issue
2eissn
0302-766Xissn
1432-0878journal_volume
231pub_type
杂志文章abstract：:Purinoceptor subtypes were localised to various tissue types present within the nasal cavity of the rat, using immunohistochemical methods. P2X3 receptor immunoreactivity was localised in the primary olfactory neurones located both in the olfactory epithelium and vomeronasal organs (VNO) and also on subepithelial nerv...
journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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更新日期：1984-01-01 00:00:00
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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更新日期：1988-10-01 00:00:00
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更新日期：1975-07-23 00:00:00
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更新日期：2011-11-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：1984-01-01 00:00:00
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journal_title：Cell and tissue research
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更新日期：2000-04-01 00:00:00
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pub_type： 杂志文章
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
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更新日期：1982-01-01 00:00:00
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journal_title：Cell and tissue research
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更新日期：1984-01-01 00:00:00
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journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：1984-01-01 00:00:00
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journal_title：Cell and tissue research
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journal_title：Cell and tissue research
pub_type： 杂志文章
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更新日期：1991-11-01 00:00:00
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journal_title：Cell and tissue research
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