Abstract：
:Dorsal root ganglia of chick embryos were cultured for one to four weeks on Maximow-slides. Puromycin was added to cultures for a pulse of 30' in a dose of 100 mug/ml medium. Particular interest was given to the ultrastructural features of the glia-neuron relations. Puromycin caused a shrinkage of the glial processes and consequently the continous glial envelope of the spinal ganglion neurons disappeared. These changes of glia-neuron contacts were reversible after a few days when puromycin was withdrawn from the medium. The newly formed glial sheaths around the neurons were comparable to those in untreated cultures and to those in vivo. The effects of an inhibition of protein synthesis caused by puromycin are discussed in relation to the effects on the cell motility, on the renewal of cell membranes and on the formation of cell contacts in nervous tissue.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Meller K,Waelsch Mdoi
10.1007/BF00225762keywords:
subject
Has Abstractpub_date
1975-07-23 00:00:00pages
431-42issue
4eissn
0302-766Xissn
1432-0878journal_volume
160pub_type
杂志文章abstract：:The Sgcb-null mouse, with knocked-down β-sarcoglycan, develops severe muscular dystrophy as in type 2E human limb girdle muscular dystrophy. The mdx mouse, lacking dystrophin, is the most used model for Duchenne muscular dystrophy (DMD). Unlike DMD, the mdx mouse has mild clinical features and shows little fibrosis in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1854-4
更新日期：2014-05-01 00:00:00
abstract：:The influence of adrenalectomy and administration of hypertonic saline on the amount of vasopressin, oxytocin, and neurophysin contained in the median eminence and the neural lobe of rats was studied by means of the following methods: (i) morphometric and microphotometric analyses of aldehyde fuchsin-stained histologi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00206271
更新日期：1983-01-01 00:00:00
abstract：:In an attempt to determine the neural control of pancreatic D cells, the pancreatic islets of the domestic fowl were examined electron microscopically from 1 to 28 days after abdominal vagotomy. Exocytotic release of many secretory granules from D cells occurred one day after vagotomy. Rough endoplasmic reticulum deve...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233732
更新日期：1980-01-01 00:00:00
abstract：:The antral hormone gastrin is the key regulator of gastric acid secretion, mucosal growth and differentiation. Gastrin is synthesized in the endocrine G-cells in the antroduodenal mucosa. We have now examined the way in which the loss of gastrin alone or gastrin plus cholecystokinin (CCK) affects the antral G-cell. Im...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-005-1110-z
更新日期：2005-07-01 00:00:00
abstract：:The notion that teeth contain stem cells is based on the well-known repairing ability of dentin after injury. Dental stem cells have been isolated according to their anatomical locations, colony-forming ability, expression of stem cell markers, and regeneration of pulp/dentin structures in vivo. These dental-derived s...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-007-0467-6
更新日期：2008-01-01 00:00:00
abstract：:Renovascular hypertension (RVH) is a progressive disease, leading to chronic kidney disease when untreated and no specific treatment is available. Therefore, development of new therapeutic modalities is imperative. RVH is triggered by renal artery stenosis and subsequent renin-angiotensin-aldosterone system activation...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-017-2602-3
更新日期：2017-08-01 00:00:00
abstract：:Synapses in the lateral septum of the murine brain have been investigated by ultrastructural immunocytochemistry, using monoclonal anti-neurophysins in both immunoperoxidase and immunogold techniques. In the region shown by light microscopy to be rich in vasopressinergic innervation, synaptic boutons containing approx...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215524
更新日期：1987-08-01 00:00:00
abstract：:Seasonal changes have been detected in the ultrastructure of brown adipose tissue (BAT) of the common shrew, Sorex araneus (a true nonhibernator) living under natural conditions and collected at the time when the most representative growth phase of the animal for the given season could be expected. In summer and autum...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233501
更新日期：1981-01-01 00:00:00
abstract：:Protein kinase C (PKC) is overexpressed in cancer, including pancreatic cancer, compared with normal tissue. Moreover, PKCα is considered one of the biomarkers for the diagnosis of cancers. In several human cancers, the claudin tight junction molecules are abnormally regulated and are thus promising molecular targets ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1287-2
更新日期：2011-12-01 00:00:00
abstract：:The effect of phenylthiourea (PTU) on the pigment epithelium and the photoreceptor cells in the developing retina of Haplochromis burtoni was studied by electron microscopy. In the retinal pigment epithelium of 6-day old embryos, both types of melanin granule (spindle-shaped and rod-shaped) are already found. PTU inhi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219054
更新日期：1977-03-09 00:00:00
abstract：:Maternal immunoglobulin-G (IgG) is known to be transported across the placental syncytiotrophoblast during the period when the human fetus is incapable of manufacturing these defensive molecules. In this study we investigated the possible role of the amniochorion, that surrounds the amniotic cavity in which the fetus ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00583405
更新日期：1995-08-01 00:00:00
abstract：:The ultrastructural distribution of fibronectin immunoreactivity was investigated in the chicken embryo during late gastrulation. Sites of binding of anti-fibronectin antibodies were ascribed to the basal lamina and associated structures, and to the cell surface. The fibronectin-rich basal lamina was resolved into a l...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217185
更新日期：1985-01-01 00:00:00
abstract：:Trichoplax, a member of the phylum Placozoa, is a tiny ciliated marine animal that glides on surfaces feeding on algae and cyanobacteria. It stands out from other animals in that it lacks an internal digestive system and, instead, digests food trapped under its lower surface. Here we review recent work on the phenotyp...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-019-03057-z
更新日期：2019-09-01 00:00:00
abstract：:Apart from the known hypothalamic controls, which have been well documented, a myriad of compounds both endogenous and exogenous have proved effective in influencing secretion of prolactin (PRL). Recent studies have shown that somatostatin (SRIF), when injected intra-atrially as a bolus, is able to inhibit PRL secreti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222371
更新日期：1983-01-01 00:00:00
abstract：:Guanosine triphosphatase (GTPase) activity was studied histo- and cytochemically in the rod outer segments of the rat retina by means of a newly developed method. Differences in the distribution pattern of the enzyme activity exist within the outer segment: the activity is more intense at the tip of the rod outer segm...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217416
更新日期：1983-01-01 00:00:00
abstract：:The distribution of immunoreactive thyrotropin-releasing hormone (TRH) in the forebrain and hypophysis of Rana catesbeiana was studied by means of specific radioimmunoassay and immunohistochemistry based on peroxidase-antiperoxidase (PAP) techniques. A relatively high concentration of immunoassayable TRH is present in...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00212220
更新日期：1983-01-01 00:00:00
abstract：:Exposure of adult brown bullheads Ictalurus nebulosus (120-450 g) to environmental hypercapnia (2% carbon dioxide in air) and subsequent recovery caused transient changes in whole body net sodium flux (JnetNa+) and net chloride flux (JnetCl-) resulting largely from changes in whole body sodium influx (JNa+in) and chlo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00319161
更新日期：1992-06-01 00:00:00
abstract：:During normal development of many vertebrate species, substantial numbers of neurons in the central and peripheral nervous system undergo naturally occurring (or programmed) cell death. For example, approximately 50% of spinal motoneurons degenerate and die at a time when these cells are establishing synaptic connecti...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050690
更新日期：1996-11-01 00:00:00
abstract：:The acrosome is a special organelle that develops from the Golgi apparatus and the endolysosomal compartment in the spermatids. Centromere protein E (CENP-E) is an essential kinesin motor in chromosome congression and alignment. This study is aimed at investigating the roles and mechanisms of kinesin-7 CENP-E in the f...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03341-3
更新日期：2020-11-25 00:00:00
abstract：:The glandular lobe of the corpus cardiacum (CC) of Locusta migratoria contains secretory cells and axon terminals. It is generally accepted that the glandular cells produce an adipokinetic hormone which stimulates the release of diglycerides from the fat body. The axon terminals are supposed to be involved in the regu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00223069
更新日期：1977-10-26 00:00:00
abstract：:The relationship between nitric oxide synthase (NOS)- and galanin-immunoreactive nerve terminals and the origin of NOS-immunoreactive nerve terminals on the motor endplates in the striated muscles of the rat esophagus was investigated. Double immunohistochemical staining revealed a dual innervation of motor endplates ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051230
更新日期：1999-02-01 00:00:00
abstract：:Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide with highly potent neurotrophic and neuroprotective effects. PACAP and its receptors occur in the retina and PACAP has been applied in animal models of metabolic retinal disorders to reduce structural and functional damage. Furthermore, PACAP...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-012-1349-0
更新日期：2012-04-01 00:00:00
abstract：:Intracerebroventricular (ICV) injection of melanin-concentrating hormone (MCH) influences feeding behavior in the goldfish and exerts an anorexigenic action in goldfish brain, unlike its orexigenic action in mammals. Despite a growing body of knowledge concerning MCH function in mammals, the role of MCH in appetite ha...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0347-5
更新日期：2007-05-01 00:00:00
abstract：:Progenitor stem cells have been identified, isolated and characterized in numerous tissues and organs. However, their therapeutic potential and the use of these stem cells remain elusive except for a few progenitor cells from bone marrow, umbilical cord blood, eyes and dental pulp. The use of bone marrow-derived hemat...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-012-1471-z
更新日期：2012-10-01 00:00:00
abstract：:Granular hormone-producing cells and agranular cells (stellate cells, including giant and pericavitary cells) were electron microscopically studied in the hypophysis of the small spotted dogfish (Scyllium canicula) up to several months after hatching. Comparisons of results obtained in embryos, newly-hatched fish and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221607
更新日期：1978-10-06 00:00:00
abstract：:The gross structure as well as the neuronal and non-neuronal components of the lamina ganglionaris of the locust Schistocerca gregaria are described on the basis of light- and electron-microscopical preparations of Golgi (selective silver) and ordinary histological preparations. The array of optic cartridges within th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00233626
更新日期：1981-01-01 00:00:00
abstract：:The number, size and structure of tendon organs were examined in leg muscles of the rat 3-19 weeks after de-efferentation performed in newborn animals by removal of the lumbosacral spinal cord. After this operation, tendon organs differentiated and grew in disused muscles and were innervated by primary sensory neurons...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214645
更新日期：1985-01-01 00:00:00
abstract：:Freeze-etch preparations of mesothelial cells taken from the peritoneum of mouse reveal the presence of vesicles invaginating the apical and the basal cell surfaces. These vesicles are scarcely seen within the cytoplasm. Long tortuous tubular profiles extend for considerable distance within the cytoplasm and are frequ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219271
更新日期：1976-10-01 00:00:00
abstract：:The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors are the principal molecular units for fast excitatory synaptic transmission in the central nervous system. The glutamate-mediated transmission efficiency of synaptic AMPA receptors is influenced by their subunit composition (GluR-A to GluR-D...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-006-0275-4
更新日期：2006-11-01 00:00:00
abstract：:An electron microscopical investigation of the pineal gland of the adult noctule bat revealed the presence of some peculiar ciliary derivatives, similar to the club-shaped outer segment of rudimentary photoreceptor cells in the pineal organ of nonmammalian vertebrates. The pinealocytes of population I can be classifie...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222058
更新日期：1977-07-26 00:00:00
