Abstract:
:The notion that teeth contain stem cells is based on the well-known repairing ability of dentin after injury. Dental stem cells have been isolated according to their anatomical locations, colony-forming ability, expression of stem cell markers, and regeneration of pulp/dentin structures in vivo. These dental-derived stem cells are currently under increasing investigation as sources for tooth regeneration and repair. Further attempts with bone marrow mesenchymal stem cells and embryonic stem cells have demonstrated the possibility of creating teeth from non-dental stem cells by imitating embryonic development mechanisms. Although, as in tissue engineering of other organs, many challenges remain, stem-cell-based tissue engineering of teeth could be a choice for the replacement of missing teeth in the future.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Yen AH,Sharpe PTdoi
10.1007/s00441-007-0467-6subject
Has Abstractpub_date
2008-01-01 00:00:00pages
359-72issue
1eissn
0302-766Xissn
1432-0878journal_volume
331pub_type
杂志文章,评审abstract::By means of a preembedding immuno-electron-microscopic technique, a large number of nerve endings containing a substance related to human growth hormone-releasing factor (hGRF) have been demonstrated in the paraventricular nucleus of the guinea pig. They made synaptic contacts primarily with dendritic shafts: 80% of t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF01239984
更新日期:1987-04-01 00:00:00
abstract::LDH is localized along various intracytoplasmatic membranes of osteoclasts. Macrophages show membrane-bound LDH only after phagocytosis of calcium hydroxylapatite, the main mineral constituent of bone. The localization of LDH in these macrophages is almost the same as in osteoclasts. The significance of this finding, ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219927
更新日期:1980-01-01 00:00:00
abstract::The ultrastructural organization of the axons of retinula cells of the eye of the wax moth Galleria mellonella are described. The axons traverse an appreciable distance between the basement membrane of the retina and the lamina ganglionaris of the optic lobe of the brain. The optic tract was reconstructed from serial ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00232837
更新日期:1976-11-18 00:00:00
abstract::Rainbow trout (Oncorhynchus mykiss) were exposed to ion-poor (soft) water to test the hypothesis that naturally induced proliferation of branchial chloride cells causes a thickening of the blood-to-water diffusion barrier. This was achieved by using a combination of scanning and transmission electron-microscopic techn...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050622
更新日期:1996-07-01 00:00:00
abstract::The chemical nature of the thickened plasma membrane of cornified cells in stratified squamous epithelium was investigated in comparison with that in noncornified epithelium. Localizations of transglutaminase, molecular weight 92,000 daltons, and detection of epidermal cysteine proteinase inhibitor were effected with ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215516
更新日期:1987-08-01 00:00:00
abstract::New genome-editing approaches, such as the CRISPR/Cas system, have opened up great opportunities to insert or delete genes at targeted loci and have revolutionized genetics in model organisms like the zebrafish. The Cre-loxp recombination system is widely used to activate or inactivate genes with high spatial and temp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2798-x
更新日期:2018-04-01 00:00:00
abstract::Human gingival fibroblasts were cultured with collagen fibrils. The precise process of collagen phagocytosis and the relationship between acid phosphatase activity and intracellular degradation of collagen were investigated by cytochemical methods at the ultrastructural level. The collagen fibrils were first engulfed ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213929
更新日期:1986-01-01 00:00:00
abstract::NdWFamide is an Aplysia cardioexcitatory tri-peptide containing D-tryptophan. To investigate the roles of this peptide, we examined the immunohistochemical distribution of NdWFamide-positive neurons in Aplysia tissues. All the ganglia of the central nervous system (CNS) contained NdWFamide-positive neurons. In particu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0707-3
更新日期:2003-04-01 00:00:00
abstract::The analysis of myenteric neurons is becoming increasingly important for the assessment of enteric nervous system injury and degeneration occurring in motor disorders of the gut. Limited information is presently available on the quantitative estimation of myenteric neurons and glial cells in paraffin-embedded colonic ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0770-5
更新日期:2009-05-01 00:00:00
abstract::Three sites of somatostatin-synthesizing perikarya, or a related antigen, were determined by immunofluorescence in the hypothalamus of the tadpole, Alytes obstetricans (Amphibia, Anura). Two sites of neurosecretory perikarya were localized in the preoptic nuclei of the anterior hypothalamus; the axons extended either ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00224373
更新日期:1978-02-24 00:00:00
abstract::The epithelial surface of the taste disc on the fungiform papillae of the frog was studied by means of freeze-fracture and conventional electron microscopy. The plasma membrane of the apical process of taste receptor cells was found to exhibit a uniform population of 10-nm intramembrane particles on its fracture face ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216883
更新日期:1982-01-01 00:00:00
abstract::Transmission electron microscopy was used to study the effects of proteolytic enzymes (collagenase, trypsin, clostripain), the calcium chelator ethyleneglycol-bis-(beta-aminoethyl ether) N,N,N',N'-tetraacetic acid (EGTA), and the calcium ionophore A 23187 on substrate adhesion and fine structure of chondrocytes and fi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00228443
更新日期:1984-01-01 00:00:00
abstract::An investigation of the stereospecificity of beta-adrenergic insulin release, its relation to alpha-adrenergic blockade and the adrenergic innervation of the pancreatic islets was performed in the mouse. It was observed that in vivo beta-adrenergic stimulation of insulin release by isopropylnoradrenaline was stereospe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221602
更新日期:1978-10-06 00:00:00
abstract::In fresh-water turtles, the bridge connecting the proximal and caudal stumps of transected spinal cords consists of regenerating axons running through a glial cellular matrix. To understand the process leading to the generation of the scaffold bridging the lesion, we analyzed the mitotic activity triggered by spinal i...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1173-y
更新日期:2011-06-01 00:00:00
abstract::The opioid peptide dynorphin A (1-17) is the third transmitter identified in the striatonigral projection, the other two being gamma-aminobutyric acid (GABA) and substance P. The ultrastructural features of the dynorphinergic terminals in substantia nigra/pars reticulata were studied using pre-embedding immunocytochem...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00329443
更新日期:1990-07-01 00:00:00
abstract::It has long been disputed whether mammalian enterochromaffin (EC-) cells contain a peptide in addition to serotonin. Previous immunohistochemical studies have provided evidence for the presence of enkephalins in EC-cells. These findings, however, are equivocal. Therefore, the problem of opioid peptides in EC-cells has...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221752
更新日期:1988-07-01 00:00:00
abstract::The vacuoles occurring in rat hepatocytes after intraportal injection of retinol (33 or 67 micrograms) were examined immunohistochemically using respective antibodies against rat albumin, human retinol-binding protein, human ceruloplasmin, human alpha 1-antitrypsin, human transferrin, and human prealbumin as represent...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00261829
更新日期:1989-08-01 00:00:00
abstract::The mole has a single pair of accessory sex organs with features of both the prostate and the seminal vesicle, for which the term prostate gland is not appropriate. Seasonal changes occuring in this gland were related to four periods: a) the quiescence period, b) the maturation period, c) the active period and d) the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218718
更新日期:1976-12-10 00:00:00
abstract::A reversible breakdown of the blood-aqueous barrier in the iridial processes of rabbits has been induced by arachidonic acid as demonstrated by the passage of horseradish peroxidase at places through the tight junctions. Freeze-fracture images reveal very discontinuous P-face ridges. However, the analysis of complemen...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213948
更新日期:1986-01-01 00:00:00
abstract::Nerve growth factor (NGF) induces morphological and physiological changes in cultured pancreatic beta-cells, including the extension of neurite-like processes. This latter effect is potentiated by dibutyryl cAMP (dbcAMP). beta-cells cultured under these conditions maintain their immunoreactivity to insulin and gamma-a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100411
更新日期:2001-09-01 00:00:00
abstract::An attempt has been made to reveal which of the nine different types of synapses in the fundus striati, discriminated in a previous study, degenerate following experimental lesions in the parafasciculo-center median complex of the cat. Two types of synaptic contacts were found to be degenerated two days after the lesi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226045
更新日期:1976-09-06 00:00:00
abstract::We have previously shown that mice deficient in the gene for the myelin-associated glycoprotein (MAG) develop normal myelin in the peripheral nerves, but show axon and myelin degeneration at eight months of age, suggesting that MAG is involved in the maintenance of axon-Schwann cell integrity. The search for molecules...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050727
更新日期:1997-01-01 00:00:00
abstract::In an organ culture system under a three-dimensional microenvironment that provides the conditions needed for odontoblast differentiation, a row of odontoblasts can be induced (Kikuchi et al. 1996, 2001). Therefore, in a newly designed three-dimensional cell culture system that fulfils the conditions necessary for odo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0882-x
更新日期:2004-08-01 00:00:00
abstract::The bilaterally paired cercal nerves of Archimantis brunneriana Sauss. leave the terminal ganglion posteriorly and then turn dorsally through muscles at the rear of the abdomen to enter the cerci, where each splits into two branches; successive branchings occur further distally in each cercus. In the distal nerve bran...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217267
更新日期:1982-01-01 00:00:00
abstract::Intercellular communication between smooth muscle cells is crucial for contractile behaviour in normal and pathologically altered urinary bladder. Since the study of coupling is difficult in situ, we established cell cultures of bladder smooth muscle cells to analyse coupling mechanisms. Microinjection of Lucifer yell...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0559-2
更新日期:2002-08-01 00:00:00
abstract::The ultrastructure of the contractile apparatus of the rat soleus muscle during the course of denervation atrophy was investigated. It was found that the ratio of thin the thick filaments increased in myofibrils of atrophying muscle fibers. Elevation of the ratio was observed as early as the second day after denervati...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00216767
更新日期:1981-01-01 00:00:00
abstract::This is the first report on the ultrastructural pattern of distribution of nicotinamide adenine dinucleotide phosphate diaphorase (NADPH-d) in endothelial cells, using the rabbit aorta, and its colocalization with the neuronal isoform (type I) of nitric oxide synthase. About 30% of the endothelial cells showed a posit...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00314551
更新日期:1993-12-01 00:00:00
abstract::Two types of mitochondria-rich cells were found in the interplatelet areas of the gills of the migrating river lamprey. Both cell types are thought to be responsible for ion-transport across the gills. In the fresh-run migrant the gills are dominated by large, flask-shaped cells which show some ultrastructural similar...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221380
更新日期:1976-10-06 00:00:00
abstract::This study describes the morphology and distribution of setae on the lateral and medial flagella of the antennules of the spiny lobster Panulirus argus in an effort to identify antennular chemoreceptors in addition to the well-studied aesthetasc chemosensilla. Setae were examined using light and electron microscopy, a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100377
更新日期:2001-06-01 00:00:00
abstract::Quantitative studies on the population of the gonadotropic cells in the pituitary of adult male rats were performed after trypsic dissociation of the pituitary glands and immunoenzymatic staining with anti-beta-LH or anti-beta-FSH antisera. Number, area and extinction of labelled cells were measured by use of an image...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217273
更新日期:1982-01-01 00:00:00