Abstract：
:It has long been disputed whether mammalian enterochromaffin (EC-) cells contain a peptide in addition to serotonin. Previous immunohistochemical studies have provided evidence for the presence of enkephalins in EC-cells. These findings, however, are equivocal. Therefore, the problem of opioid peptides in EC-cells has been re-examined in the gastro-intestinal mucosa of dog, guinea-pig and man. A battery of antisera against derivatives of pro-opiomelanocortin, pro-enkephalin and pro-dynorphin have been applied to semithin serial sections of the tissues, in combination with fluorescence histochemistry and serotonin immunocytochemistry. Our findings indicate that EC-cells of the investigated species contain pro-dynorphin-related peptides, i.e. dynorphin A and alpha-neo-endorphin, but no derivatives from pro-opiomelanocortin or pro-enkephalin. Since remarkable interspecies variations occur with respect to the number and staining characteristics of opioid immunoreactive EC-cells, it is concluded that pro-dynorphin shows specific routes of post-translational processing depending upon the species and the gastro-intestinal segment investigated. Future studies should focus on the mutual relationships between serotonin and dynorphins and on the physiological significance of these peptides in the gastrointestinal tract.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Cetin Ydoi
10.1007/BF00221752subject
Has Abstractpub_date
1988-07-01 00:00:00pages
173-9issue
1eissn
0302-766Xissn
1432-0878journal_volume
253pub_type
杂志文章abstract：:Neural stem cells (NSCs) are a subtype of tissue-specific progenitor cells capable of extended self-renewal and the ability to generate all major cell types of nervous tissue, such as neurons, astroglia and oligodendroglial cells. Recent studies suggest that salient patterning in anterior-posterior and dorsal-ventral ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-004-0923-5
更新日期：2004-10-01 00:00:00
abstract：:Black tiger shrimps (Penaeus monodon) are able to survive and can be reared under various salinities, possibly by the cellular adaptation of their excretory system, particularly the antennal gland, which is known to regulate body fluid in crustaceans. We have investigated the morphological and biochemical alterations ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-010-0971-y
更新日期：2010-06-01 00:00:00
abstract：:Although the cerebrospinal fluid-contacting neurons of the avian paraventricular organ exhibit considerable amounts of catecholamines, they show no tyrosine hydroxylase immunoreactivity. In the quail embryo, the development of these neurons has been studied using the paraformaldeyde-glutaraldeyde method for the fluore...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00307970
更新日期：1995-07-01 00:00:00
abstract：:The distribution of serotonin-immunoreactive cells in the lung of 4 species of reptiles was investigated. Serotonin-containing cells were found forming groups in the interconnecting septa in all 4 species studied, and also as solitary cells in Testudo graeca and Mauremys caspica. Serotonin-containing cells were also l...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216504
更新日期：1987-06-01 00:00:00
abstract：:The extracellular matrix is involved in various morphogenetic processes which are accompanied by changes in its physicochemical properties and spatial organization. In the adult brain it contributes to cellular communication and the regulation of neuronal activity. The present study deals with the postnatal appearance...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050790
更新日期：1997-04-01 00:00:00
abstract：:The attachment of the body of the snail Lymnaea stagnalis to the shell was studied by histochemistry and light and electron microscopy. Muscles of the body wall insert into the connective tissue by way of long thin projections of sarcolemma. The muscle cells end under the basement membrane of a specialised area of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224663
更新日期：1976-08-26 00:00:00
abstract：:Two types of horizontal cells, H1 and H2, were classified using the Golgi technique on flat mounts of the retina of the frog. Cell type H1 possesses rather short, thick dendrites; the diameter of its dendritic field ranges from 40-90 micrometers. H2-cell displays long and thin dendrites; the diameter of its dendritic ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216747
更新日期：1981-01-01 00:00:00
abstract：:Ionizing irradiation is an effective treatment for intracranial tumors but is limited by the potential adverse effects induced in surrounding normal brain. These effects can include cognitive impairments, and whereas the pathogenesis of such injury has not yet been definitively established, it may involve injury to th...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-007-0480-9
更新日期：2008-01-01 00:00:00
abstract：:By use of the immunofluorescence technique TSH-, LH- and ACTH-cells were localized in the hypophysis of tadpoles of Xenopus laevis. The first signs of the activity of these cells were observed in early stages of the development, i.e., stage 39 for ACTH, and stage 42 for TSH and LH. ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00216218
更新日期：1982-01-01 00:00:00
abstract：:Rat blood monocytes contain granules of two types, primary and secondary granules, which can be distinguished on morphological grounds. Secondary granules have a halo between the limiting membrane and the matrix; primary granules have no halo and are generally more elongate than the secondary granules. In addition, th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226665
更新日期：1977-11-30 00:00:00
abstract：:Kruppel-like factor 4 (KLF4) is a zinc-finger-type transcription factor with a restricted expression pattern during skeletal development. We have previously shown that KLF4 represses osteoblast mineralization concomitant with a down-regulation in the expression of a number of osteoblastic genes, both in vivo and in vi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1931-8
更新日期：2014-10-01 00:00:00
abstract：:Transplantation of ligament-tissue-derived stem cells has become a promising approach in the repair of injured ligament. Neovascularization plays an important role in ligament healing and remodeling. Recently, human umbilical-cord-blood-derived CD34+ cells have been reported to contribute to neoangiogenesis. Therefore...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2250-4
更新日期：2015-12-01 00:00:00
abstract：:CYCLE (CYC) and CLOCK (CLK) are transcriptional activators of the circadian clock genes, period (per) and timeless (tim), binding at E-boxes of their upstream regulatory region in Drosophila. CYC-like and CLK-like immunohistochemical reactivities (CYC-ir and CLK-ir) were investigated in the ground cricket, Allonemobiu...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0534-z
更新日期：2008-02-01 00:00:00
abstract：:In this study, we focus on the specific contribution of β integrin-like protein to adhesion-mediated events in molluscan larval cells in culture that could not have been investigated within the whole animal. An analysis of disturbances to cell-substratum adhesion, caused by the integrin receptor inhibiting Arg-Gly-Asp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2122-y
更新日期：2015-08-01 00:00:00
abstract：:The use of porcine hepatocytes in xenotransplantation, bioartificial liver support or pharmacological approaches demands serum-free cryopreservation protocols yielding high quality, viable, functional hepatocytes. Here, primary porcine hepatocytes were frozen without serum in liquid nitrogen by the use of a computer-a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0894-6
更新日期：2004-07-01 00:00:00
abstract：:Acute necrotizing pancreatitis (ANP) is a common gastrointestinal cause of emergency admissions in dogs and humans and can lead to a systemic inflammatory response syndrome resulting in multiple organ dysfunction syndrome. Among the various complications associated with ANP, acute lung injury (ALI) or acute respirator...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-020-03211-y
更新日期：2020-05-01 00:00:00
abstract：:This work describes the origin and development of about 200 tension receptor cells located around the anterior attachment site of the locust ovipositor muscle and their migration to their final position on the muscle fibres. The locust ovipositor muscle is the only insect system in which more than 100 tension receptor...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0498-z
更新日期：2007-12-01 00:00:00
abstract：:Microinjection of DNAase I, which is known to form a specific complex with G-actin, induces characteristic changes in cytoplasmic streaming, locomotion and morphology of the contractile apparatus of A. proteus. Light microscopical studies show pronounced streaming originating from the uroid and/or the retracting pseud...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236075
更新日期：1979-07-17 00:00:00
abstract：:The posterior rhombencephalic tela choroidea of the bullfrog was examined by electron microscopy. This membrane, the pia-ependymal roof of the caudal hindbrain, contains a large central region characterized by cuboidal ependymal cells which surround sizable microscopic apertures -- the interependymal pores. Ultrastruc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220439
更新日期：1979-11-01 00:00:00
abstract：:Prostatic carcinoma affects 1 in 11 men and targets bone with sclerotic metastases. The study of prostate carcinoma growth in bone has been hampered by the lack of suitable animal models. We have developed an in vivo model of prostate carcinoma growth in bone by inoculating three human prostate carcinoma cell lines (P...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-001-0503-x
更新日期：2002-03-01 00:00:00
abstract：:Isotocinergic (IT) neurons show physiological and morphological characteristcs that are similar to those of the other preoptic neuroendocrine cells in the goldfish. Preoptic IT cells show resting membrane potentials of 20-55 mV, action potentials of up to 100 mV, and physiological evidence of axonal branching. Dye-mar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00239217
更新日期：1979-10-02 00:00:00
abstract：:The existence of the surface-connected canalicular system (SCCS) has been demonstrated in semithick sections of the frog thrombocytes by the use of a high voltage electron microscope. The SCCS of the thrombocytes in Rana catesbeiana and Rana nigromaculata consists of numerous canaliculi and vesicles with a diameter of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00237001
更新日期：1979-10-01 00:00:00
abstract：:The ability of levamisole (LVS) to correct the effect of thymectomy on splenic T-cell population in Bufo bufo larvae was tested. Using the nonspecific acid alpha-naphthyl acetate esterase (ANAE) technique, the T-lymphocytes displayed a characteristic reddish brown spot (T-pattern). The total number of white cells per ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00204789
更新日期：1982-01-01 00:00:00
abstract：:It is a well-established fact that the sympathetic, parasympathetic and enteric nervous systems are affected at early stages in Parkinson's disease (PD). However, it is not yet clarified whether the earliest pathological events preferentially occur in any of these three divisions of the autonomic nervous system (ANS)....
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-018-2851-9
更新日期：2018-07-01 00:00:00
abstract：:Enteroendocrine cells containing glucagon-, substance P-, neurotensin- and VIP-like substances have been demonstrated immunocytochemically in the gut of Barbus conchonius. Mainly based on the distribution of the immunoreactive endocrine cells in this and a previous study, at least eight different enteroendocrine cell ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00229200
更新日期：1984-01-01 00:00:00
abstract：:The livers of Xenopus laevis, grouped by chronological age (0.5, 2 and 3 yrs), were studied electron microscopically. Ultrastructurally most of the melanin granules in the mature female liver showed an internal structure similar to the melanin granules of the oocytes. The hepatic melanin granules of immature females a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00220293
更新日期：1977-12-19 00:00:00
abstract：:Single Golgi impregnated visual cells and their axons were treated from the retina to the first synaptic layer (lamina) in serial electron microscopic sections. This analysis of the retina-lamina projection was undertaken in the upper dorso-median eye region which is known to be involved in the perception of polarized...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218590
更新日期：1975-11-17 00:00:00
abstract：:The association between adipose tissue and immunity has been established and fat-associated lymphoid clusters (FALCs) are considered as a source of immune cells. We discovered lymphoid clusters (LCs) in mouse mediastinal fat tissues (MFTs). In Th1-biased C57BL/6N (B6), Th2-biased DBA/2Cr (DBA) and autoimmune-prone MRL...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1889-6
更新日期：2014-09-01 00:00:00
abstract：:Follicular dendritic cells (FDCs) are immune accessory cells found in the follicles of secondary lymphoid organs where they promote B cell maturation in germinal centers (GCs) that develop following antigen exposure. Recently, we published a method for isolating functional murine FDCs in high purity. We reasoned that ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0566-4
更新日期：2008-04-01 00:00:00
abstract：:The distribution of FMRFamide-like immunoreactive cell bodies and fibers in the nervous system of the earthworm Lumbricus terrestris has been studied by means of immunocytochemistry. The cerebral ganglion contains 150-170 immunoreactive nerve cells that are organized into six major groups in the rostral and five major...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050843
更新日期：1997-06-01 00:00:00
