Abstract:
:Purinoceptor subtypes were localised to various tissue types present within the nasal cavity of the rat, using immunohistochemical methods. P2X3 receptor immunoreactivity was localised in the primary olfactory neurones located both in the olfactory epithelium and vomeronasal organs (VNO) and also on subepithelial nerve fibres in the respiratory region. P2X5 receptor immunoreactivity was found in the squamous, respiratory and olfactory epithelial cells of the rat nasal mucosa. P2X7 receptor immunoreactivity was also expressed in epithelial cells and colocalised with caspase 9 (an apoptotic marker), suggesting an association with apoptosis and epithelial turnover. P2Y1 receptor immunoreactivity was found within the respiratory epithelium and submucosal glandular tissue. P2Y2 receptor immunoreactivity was localised to the mucus-secreting cells within the VNO. The possible functional roles of these receptors are discussed.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Gayle S,Burnstock Gdoi
10.1007/s00441-004-0979-2keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
27-36issue
1eissn
0302-766Xissn
1432-0878journal_volume
319pub_type
杂志文章abstract::Myelin formation in cultures of previously dissociated spinal cord from foetal mice is described. In addition to the expected pattern of myelination, in which axons are closely wrapped by myelin lamellae, redundant folds of myelin have been found, as have double sheaths surrounding a single axon. Hypotheses concerning...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223265
更新日期:1975-09-16 00:00:00
abstract::Cytochemical methods for the demonstration of p-nitrophenylphosphatase (p-NPPase) at the electron-microscopic level were applied to avian osteoclasts to elucidate some of the functional differences among ruffled border, other membrane systems, and cellular organelles. The localization of p-NPPase activity occurred in ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218381
更新日期:1986-01-01 00:00:00
abstract::The ontogeny of protein gene product 9.5 (PGP 9.5), serotonin (5-HT), calcitonin gene-related peptide (CGRP), and calcitonin (CT) immunoreactivity was evaluated in small-granule endocrine cells of hamster laryngotracheal epithelium from fetal day 11 to adulthood. Two centrifugal (proximal-to-distal) patterns of differ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00305382
更新日期:1994-01-01 00:00:00
abstract::The regeneration of the vallate papilla in the rat was studied by both light and electron microscopy. The papillae were excised and regeneration was studied at time intervals of 3 to 45 days. It was found that the vallate papilla is capable of regeneration after both partial and total papillectomies. The regenerated p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225338
更新日期:1978-10-30 00:00:00
abstract::Rhabdomeres of the Drosophila melanogaster canoemisl mutant ommatidia were twisted, branched, and often fused to each other. A considerable proportion of rhabdomeres were found to have fallen below the retinal basement membrane. Electron-microscopic observations of the mutant ommatidia revealed that microvilli, the su...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900107
更新日期:1999-12-01 00:00:00
abstract::The genes encoding transmembrane glycoproteins of the cadherin family, i.e., the Ca(2+)-dependent cell-cell adhesion molecules, are typically expressed in cell-type- or cell-lineage-specific patterns. One of them, vascular endothelial (VE)-cadherin, is widely considered to be specific for vascular endothelia in which ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-008-0718-1
更新日期:2009-01-01 00:00:00
abstract::Box jellyfish have the most elaborate sensory system and behavioural repertoire of all cnidarians. Sensory input largely comes from 24 eyes situated on four club-shaped sensory structures, the rhopalia, and behaviour includes obstacle avoidance, light shaft attractance and mating. To process the sensory input and conv...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0393-7
更新日期:2007-07-01 00:00:00
abstract::The ultrastructural distribution of fibronectin immunoreactivity was investigated in the chicken embryo during late gastrulation. Sites of binding of anti-fibronectin antibodies were ascribed to the basal lamina and associated structures, and to the cell surface. The fibronectin-rich basal lamina was resolved into a l...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217185
更新日期:1985-01-01 00:00:00
abstract::The desert locust Schistocerca gregaria is a major agricultural pest in North Africa and the Middle East. As such, it has been intensely studied, in particular with respect to population dynamics, sensory processing, feeding behavior flight and locomotor control, migratory behavior, and its neuroendocrine system. Bein...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-018-2844-8
更新日期:2018-10-01 00:00:00
abstract::The true surface of rabbit spinal ganglion neurons has been made directly accessible to scanning electron-microscope observation after removal of both the connective tissue and satellite cells that normally cover it. The neuronal surface is characterized by a profusion of slender projections whose shapes have been det...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00297502
更新日期:1990-04-01 00:00:00
abstract::The ultrastructure of the sinus gland of the fiddler crab, Uca pugnax, was investigated and found to be similar to that in other crustaceans. Five types of neurosecretory axon terminals were tentatively identified on the basis of the size, shape, and electron density of granules within the axons. Release of neuro-secr...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222805
更新日期:1975-12-29 00:00:00
abstract::A well-developed Golgi apparatus and rough and smooth endoplasmic reticulum in the principal cells of the mouse epididymis indicate active protein synthesis. Studies have shown that epididymal secretions are essential for sperm maturation. In a previous study, two wheat-germ agglutinin (WGA)-binding glycoproteins, GP-...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00340863
更新日期:1991-09-01 00:00:00
abstract::Since the advent of transmission electron microscopy of tissues capable of growth and regeneration, cell and developmental biologists have postulated that the undifferentiated cells observed within these tissues represent tissue-specific stem or progenitor cells. However, no studies have addressed the issue of whether...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0641-9
更新日期:2002-12-01 00:00:00
abstract::Semaphorin 3A (Sema3A) axon repellant serves multiple developmental functions. Sema3A mRNAs are expressed in epithelial and mesenchymal components of the developing incisor in a dynamic manner. Here, we investigate the functions of Sema3A during development of incisors using Sema3A-deficient mice. We analyze histomorp...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1839-3
更新日期:2014-07-01 00:00:00
abstract::The expression patterns of three microtubule-associated proteins (MAP1A, MAP1B, and MAP2A&B) were investigated in the developing optic tectum. Expression of MAP1B and middle-molecular-weight peptide of neurofilament (NF-M) was first observed in the same mesencephalic cells on day 3 of incubation, indicating that neuro...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0796-z
更新日期:2003-12-01 00:00:00
abstract::The lobula descending neuron (LDN) of dipterous insects is a unique nerve cell (one on each side of the brain) that projects directly from the lobula complex of the optic lobes to neuropil in thoracic ganglia. In the supraoesophageal ganglia the LDN has two prominent groups of branches of which at least one is dendrit...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218365
更新日期:1982-01-01 00:00:00
abstract::During developmental critical periods, external stimuli are crucial for information processing, acquisition of new functions or functional recovery after CNS damage. These phenomena depend on the capability of neurons to modify their functional properties and/or their connections, generally defined as "plasticity". Al...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-011-1293-4
更新日期:2012-07-01 00:00:00
abstract::Vesicular transport involves SNARE (soluble- N-ethylmaleimide-sensitive-factor-attachment-protein-receptor) proteins on transport vesicles and on target membranes. Syntaxin 13 is a SNARE enriched in brain, associated with recycling endosomes; its overexpression in PC12 cells promotes neurite outgrowth. This suggests a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0600-5
更新日期:2002-08-01 00:00:00
abstract::Rab11, a small monomeric GTPase associated with recycling endosomes, is a key molecule in the regulation of vesicular trafficking and is involved in the development and differentiation of many Drosophila tissues through interaction with diverse signaling pathways. In this study, we report for the first time that Rab11...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2500-0
更新日期:2017-02-01 00:00:00
abstract::Changes in the organisation and composition of extracellular matrix in human endometrium during the menstrual cycle and early pregnancy have been assessed by immunofluorescence. Amongst interstitial components, type-III and type V-collagens and fibronectin are present in endometrial stroma throughout the menstrual cyc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221758
更新日期:1988-07-01 00:00:00
abstract::The vascular architecture of the rat testis and spermatic cord was studied by a corrosion cast technique combined with scanning and transmission electron microscopy, and light microscopy. The casts preserve the endothelial impressions of the vessels and enable them to be differentiated into the various vascular compon...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217176
更新日期:1985-01-01 00:00:00
abstract::The presence of immunoreactive enkephalin, dynorphin, vasoactive intestinal polypeptide, cholecystokinin, substance P and neuropeptide Y in nerve fibers that project to the guinea-pig inferior mesenteric ganglion was analysed, after different denervation and ligation procedures. A quantitative analysis demonstrates th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219741
更新日期:1988-09-01 00:00:00
abstract::Employing electron-microscopic methods that help retain polyanionic materials, we describe the extracellular coverings of a sea urchin (Lytechinus variegatus) throughout ontogeny. The surface of the embryo is covered by a two-layered cuticle (commonly called the hyaline layer), which in turn is covered by a granular l...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218028
更新日期:1985-01-01 00:00:00
abstract::Previously, we showed that synchronous autophagy occurred in the corpora allata during the declining phase of juvenile hormone synthesis in mated adult females of the cockroach Diploptera punctata. At the onset of this process, conspicuous whorl-like autophagosomes were often observed. Each consisted of a ribosome-con...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050764
更新日期:1997-02-01 00:00:00
abstract::An ectodermal network of nerve cells has been observed in the echinopluteus. It seems to connect the ectodermal cell bodies with each other and with deeper parts of the nerve system. Together with the neurohumour containing parts of the ventral and oral ciliated bands, the nerve cells probably provide the larva with t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219793
更新日期:1977-04-07 00:00:00
abstract::Myogenesis is a complex process in which committed myogenic cells differentiate and fuse into myotubes that mature into the muscle fibres of adult organisms. This process is initiated by a cascade of myogenic regulatory factors expressed upon entry of the cells into the myogenic differentiation programme. However, ext...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1364-1
更新日期:2012-06-01 00:00:00
abstract::Vitrification of biological specimens in liquid nitrogen can be achieved under high pressure (2,100 bars). This procedure obviates the use of aldehyde fixation and cryoprotection (glycerol). The present work demonstrates its applicability to the freeze-etching of mammalian brain tissue. Freeze-fracture repicas from ra...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00237626
更新日期:1980-01-01 00:00:00
abstract::Regeneration of rat mast cells was studied by TEM from 10 s to 48 h after secretion of histamine induced by compound 48/80. During the first 2 h, small intracellular cavities, formed during compound exocytosis and containing non-membrane-bound remnants of the granules, tended to coalesce, and after 2 h of incubation r...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238658
更新日期:1981-01-01 00:00:00
abstract::This is the first detailed report about the collar enamel of the teeth of Polypterus senegalus. We have examined the fine structure of the collar enamel and enamel organ of Polypterus during amelogenesis by light and transmission electron microscopy. An immunohistochemical analysis with an antibody against bovine amel...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1305-4
更新日期:2012-02-01 00:00:00
abstract::The aluminium-formaldehyde (ALFA) histofluorescence method was used to study the innervation of the gill of the marine bivalve mollusc Mytilus edulis and the results were contrasted with those obtained with the standard formaldehyde-induced-fluorescence (FIF) method. The ALFA method produced more fluorescing structure...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214696
更新日期:1982-01-01 00:00:00