Abstract：
:As a companion to an earlier study, the morphometric attributes of stimulated (blast-derived) lymphocytes in mouse axillary lymph nodes have been established using stereological and autoradiographic methods. Blast transformation was induced in vivo with dinitrochlorobenzene (DNCB) and stimulated cells were labelled with tritiated thymidine. Random samples of cells were taken for light and electron microscopic morphometry. In comparison to the unstimulated lymphocyte, the stimulated cell increased in size and possessed a greater plasma membrane surface area. Increase in cell size was the result of increases in the volumes of all measured subcellular compartments both in the nucleus and the cytoplasm. Heterogeneity of the stimulated cell population precludes firm conclusions regarding the significance of all these ultrastructural changes, though alterations in cell surface are discussed in the context of known biochemical differences accompanying blastogenesis.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Al-Hamdani MM,Atkinson ME,Mayhew TMdoi
10.1007/BF00233538subject
Has Abstractpub_date
1981-01-01 00:00:00pages
643-9issue
3eissn
0302-766Xissn
1432-0878journal_volume
215pub_type
杂志文章abstract：:Granular hormone-producing cells and agranular cells (stellate cells, including giant and pericavitary cells) were electron microscopically studied in the hypophysis of the small spotted dogfish (Scyllium canicula) up to several months after hatching. Comparisons of results obtained in embryos, newly-hatched fish and ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00221607
更新日期：1978-10-06 00:00:00
abstract：:Putative neural stem cells have been identified within the enteric nervous system (ENS) of adult rodents and cultured from human myenteric plexus. We conducted studies to identify neural stem cells or progenitor cells within the submucosa of adult human ENS. Jejunum tissue was removed from adult human subjects undergo...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1130-9
更新日期：2011-05-01 00:00:00
abstract：:Beta-defensin 103 (DEFB103) shares little homology with 8 other members of the bovine beta-defensin family and in other species DEFB103 protein has diverse functions, including antimicrobial activity, a chemoattractant for dendritic cells, enhancing epithelial wound repair and regulating hair colour. Expression of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-015-2258-9
更新日期：2016-02-01 00:00:00
abstract：:The orderly arrangement of fibroblasts and collagen in tendons and ligaments suggests that these cells may have precise relationships with one another and with the collagen fibrils. The spatial organization of rat tail tendon was therefore examined using scanning and transmission electron microscopy and by reconstruct...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00217304
更新日期：1984-01-01 00:00:00
abstract：:Male/female differences in enzyme activity and gene expression in the liver are known to be attenuated with ageing. Nevertheless, the effect of ageing on liver structure and quantitative cell morphology remains unknown. Male and female Wistar rats aged 2, 6, 12 and 18 months were examined by means of stereological tec...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-016-2490-y
更新日期：2016-12-01 00:00:00
abstract：:The distribution and nature of 125I-atrial natriuretic peptide binding sites have been examined in the brain and pituitary gland of the toad, Bufo marinus, using tissue section autoradiography, affinity cross-linking and electrophoresis, guanylyl cyclase assays and molecular analysis of natriuretic peptide receptor C ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000266
更新日期：2000-10-01 00:00:00
abstract：:Morphogenesis of the arcuate nucleus of the rat from the 15th fetal day to the 6th postnatal day was investigated light and electron microscopically. The arcuate neurons exhibit a gradual development after the 15th fetal day. All cytoplasmic constituents are present in these nerve cells already during the last days of...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00236893
更新日期：1979-08-03 00:00:00
abstract：:The ultrastructure of the calcium-sensitive (Ca-s) (PAS-positive) cells of the pars intermedia was investigated in eels kept in hypo- and hyperosmotic environments. Although the cells were moderately active in fresh water (FW), they were highly stimulated in deionized water (DW) and displayed an enlarged Golgi apparat...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00210015
更新日期：1981-01-01 00:00:00
abstract：:Horseradish peroxidase (HRP) was injected into the left dorsal column nuclei of adult cats. Large dorsal funiculi axons of the C3, C5, C8 and L7 segments were searched for HRP-activity after 12, 24, 36 and 48h using light and electron microscopy. Accumulations of intra-axonal HRP-positive bodies occurred at nodes of R...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050513
更新日期：1996-01-01 00:00:00
abstract：:We have recently identified a tachykinin-related peptide (AmTRP) from the mushroom bodies (MBs) of the brain of the honeybee Apis mellifera L. by using direct matrix-assisted laser desorption/ionization with time-of-flight mass spectometry and have isolated its cDNA. Here, we have examined prepro-AmTRP gene expression...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-004-0865-y
更新日期：2004-05-01 00:00:00
abstract：:Molting in shrimp is controlled by the molt-inhibiting hormone (MIH) and ecdysone. MIH inhibits the synthesis of ecdysone in the Y-organ, resulting in molt suppression; it is a neuropeptide member belonging to the eyestalk CHH/MIH/GIH family. The cloning of MIH (formerly MIH-like) of the shrimp Metapenaeus ensis has b...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000299
更新日期：2001-01-01 00:00:00
abstract：:Many noctuid moth species perceive ultrasound via tympanic ears that are located at the metathorax. Whereas the neural processing of auditory information is well studied at the peripheral and first synaptic level, little is known about the features characterizing higher order sound-sensitive neurons in the moth brain....
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-013-1749-9
更新日期：2014-02-01 00:00:00
abstract：:We conducted an immunoelectron-microscopic study for histamine (HA) in the enterochromaffin-like (ECL) cells of normal rats and rats given alpha-fluoromethylhistidine (alpha-FMH, 3 mg/kg per hour) via osmotic minipumps over a period of 24 h. The indirect immunoperoxidase procedure utilized a mouse monoclonal antibody ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100448
更新日期：2001-11-01 00:00:00
abstract：:The expression of the gene for vasoactive intestinal polypeptide (VIP) and peptide histidine methionine (PHM) in the human gastrointestinal tract was studied by in situ hybridization and Northern blotting for PHM/VIP mRNA and immunocytochemistry using specific antisera against the bioactive peptides PHM and VIP. In th...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00306108
更新日期：1994-05-01 00:00:00
abstract：:The distribution and abundance of nitric oxide synthase (NOS)-containing neurons and their terminals in the gastrointestinal tract of the guinea-pig were examined in detail using NADPH diaphorase histochemistry and NOS immunohistochemistry. NOS-containing cell bodies were found in the myenteric plexus throughout the g...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00303090
更新日期：1994-07-01 00:00:00
abstract：:The carotid body is a peripheral chemoreceptor that detects decreases in arterial pO2 and subsequently activates the carotid sinus nerve. The hypoxia-evoked activity of the carotid sinus nerve has been suggested to be modulated by glutamate. In the present study, we investigate the immunohistochemical localization of ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-014-1921-x
更新日期：2014-10-01 00:00:00
abstract：:The localization of (Na+-K+) ATPase in the intact electrocyte of the electric organ of Electrophorus electricus (L.) and its subcellular fractions was investigated by biochemical and cytochemical methods. The distribution of AChE activity in the subcellular fractions was also comparatively analysed with this enzyme se...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00226673
更新日期：1977-11-30 00:00:00
abstract：:PU.1, which is a transcription factor, promotes the terminal differentiation of alveolar macrophages (AMs). Its expression is regulated by granulocyte/macrophage colony-stimulating factor (GM-CSF). In this study of AMs in newborn rats, we performed immunohistochemical staining, acid phosphatase staining, reverse trans...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-007-0405-7
更新日期：2007-07-01 00:00:00
abstract：:The production of nerve growth factor (NGF) in peripheral organs may play a role in the pathophysiology of hypertension and in obstructive disorders of the bladder outlet. We have been examining the cellular processes of NGF delivery and secretion in smooth muscle. NGF secretion from vascular smooth muscle cells (VSMC...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050861
更新日期：1997-07-01 00:00:00
abstract：:Neurointermediate lobes from adult or 10-day-old rats were implanted by a stereotaxic procedure into the third ventricle of adult male rats, in an area close to the paraventricular nucleus. They were examined, using immunocytochemical and ultrastructural techniques, at times ranging from 1 week to 8 months. All grafts...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00224123
更新日期：1989-02-01 00:00:00
abstract：:Isotocinergic (IT) neurons show physiological and morphological characteristcs that are similar to those of the other preoptic neuroendocrine cells in the goldfish. Preoptic IT cells show resting membrane potentials of 20-55 mV, action potentials of up to 100 mV, and physiological evidence of axonal branching. Dye-mar...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00239217
更新日期：1979-10-02 00:00:00
abstract：:While brain-derived neurotrophic factor (BDNF) messenger RNA (mRNA) has been localized in the developing gustatory epithelium, little information is available about neurotrophin-3 (NT-3) mRNA expression pattern in the prenatal developing gustatory and lingual epithelium. In the present study, using in situ hybridizati...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410051092
更新日期：1998-06-01 00:00:00
abstract：:Ependymal cells located above the ventricular zone of the lateral, third, and fourth ventricles and the spinal cord are thought to form part of the adult neurogenic niche. Many studies have focused on ependymal cells as potential adult neural stem/progenitor cells. To investigate the functions of ependymal cells, a si...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-019-03132-5
更新日期：2020-03-01 00:00:00
abstract：:The smooth muscle of rabbit portal vein was studied by electron microscopy with particular emphasis on the mechanical linkage between the muscle cells and on the distribution of connective tissue. The media of this vein is composed of inner circular and outer longitudinal muscle layers which are orientated almost perp...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00237614
更新日期：1980-01-01 00:00:00
abstract：:The pineal gland structure and ultrastructure in the Northern (Blarina brevicauda) and Southern short-tailed shrew (Blarina carolinensis) are described by light and electron microscopy. Results observed were similar to other mammals of Insectivora described previously, specifically, the hedgehog (Erinaceus europaeus) ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-018-2897-8
更新日期：2018-12-01 00:00:00
abstract：:The origin of cobblestone-like polygonal cells (the most numerous in renal glomerular cell culture) remains controversial; they could be either dedifferentiated podocytes or parietal epithelial cells (PECs) of Bowman's capsule. Poor cellular outgrowth from glomeruli devoid of Bowman's capsule (decapsulated glomeruli) ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100380
更新日期：2001-06-01 00:00:00
abstract：:Maternal immunoglobulin-G (IgG) is known to be transported across the placental syncytiotrophoblast during the period when the human fetus is incapable of manufacturing these defensive molecules. In this study we investigated the possible role of the amniochorion, that surrounds the amniotic cavity in which the fetus ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00583405
更新日期：1995-08-01 00:00:00
abstract：:Neuroblastoma cells grown on substrates in culture develop long processes and assume the morphology of normal neurons as judged light microscopically. The development of synapses in the cultured tissue is studied by periodic electron microscopic examination of the areas of contact between cells. The initial explants a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00232282
更新日期：1980-01-01 00:00:00
abstract：:The effects of the administration of thyroxine (T4) on the postnatal cytodifferentiation of granular convoluted tubule (GCT) cells of the submandibular gland (SMG) of Lewiss-Webster mice were studied by light and electron microscopy. From birth, mice of both sexes were injected daily with T4 (sc 0.4 micrograms/g BW) a...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218202
更新日期：1987-05-01 00:00:00
abstract：:Desmin is a muscle-specific type III intermediate filament essential for proper muscular structure and function. In human, mutations affecting desmin expression or promoting its aggregation lead to skeletal (desmin-related myopathies), or cardiac (desmin-related cardiomyopathy) phenotypes, or both. Patient muscles dis...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-014-2016-4
更新日期：2015-06-01 00:00:00
