Fine structure of seminiferous tubules from prenatally irradiated rats.

Abstract:

:The ultrastructure of the seminiferous tubules was studied in rats that had been subjected to whole body irradiation on the 19th day of gestation. The seminiferous tubules from 3 months-old irradiated animals are devoid of germ cells and contain only Sertoli cells. Compared with controls of the same age, the seminiferous tubule basal membrane is thickened and multilayered and several alterations are observed in the Sertoli cells. The most characteristic of these alterations are: (a) an abnormal number of nuclear heterochromatin clumps, (b) the presence of numerous cytoplasmic vacuoles and various sized lipid droplets, (c) elaborate interdigitations and junctions between adjacent cells, and (d) the presence of anomalous ectoplasmic specializations disposed perpendicularly to the Sertoli cell membrane.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Abreu I,David-Ferreira JF

doi

10.1007/BF00218294

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

143-52

issue

1

eissn

0302-766X

issn

1432-0878

journal_volume

222

pub_type

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