Transmission and scanning electron-microscopic observations on tanycytes in the mediobasal hypothalamus and the median eminence of adrenalectomized rats.

Abstract:

:Tanycytes in the median eminence (ME) of the rat exhibit morphological features suggesting their possible participation in transport phenomena. After adrenalectomy, which modifies the hypothalamo-hypophyseal axis, they undergo morphological changes characterized by an accumulation of lipid droplets, an increased number of bleb-like protrusions at their apex, as well as an increased pinocytosis of intraventricularly injected horseradish peroxidase (HRP). In addition, after adrenalectomy an increased number of vacuoles appears at the level of the tubero-infundibular sulci. Their intracellular location in the tanycytes is demonstrated by an intraventricular injection of HRP. The significance of these vacuoles is discussed in relation to the hydroelectrolytic modifications associated with the state of adrenalectomy.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Brion JP,Depierreux M,Couck AM,Flament-Durand J

doi

10.1007/BF00215708

subject

Has Abstract

pub_date

1982-01-01 00:00:00

pages

643-55

issue

3

eissn

0302-766X

issn

1432-0878

journal_volume

221

pub_type

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