Abstract:
:The grey level index (= GLI) and the fresh voluem were determined with the image analyser Micro-Videomat for the nucl. n. facialis after axotomy of the left n. facialis. The experiments were performed on 10 rats in different stages of ontogenesis. The GLI is a quantitative parameter which could be quickly obtained and which demonstrated quantitative changes during retrograde reaction in the respective centres. A decrease in the fresh volumes of the affected nucl. n. facialis could also be demonstrated. The meaning of GLI is discussed.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Zilles K,Schleicher A,Kretschmann HJdoi
10.1007/BF00218176subject
Has Abstractpub_date
1978-07-05 00:00:00pages
285-99issue
2eissn
0302-766Xissn
1432-0878journal_volume
190pub_type
杂志文章abstract::Conventional two-dimensional cell monolayers do not provide the geometrical, biochemical and mechanical cues found in real tissues. Cells in real tissues interact through chemical and mechanical stimuli with adjacent cells and via the extracellular matrix. Such a highly interconnected communication network extends alo...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-013-1589-7
更新日期:2013-04-01 00:00:00
abstract::Comparing the distribution of cytoplasmic particles and organelles between different experimental conditions can be challenging due to the heterogeneous nature of cell morphologies. The border-to-border distribution method was created to enable the quantitative analysis of fluorescently labeled cytoplasmic particles a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2265-x
更新日期:2016-02-01 00:00:00
abstract::We have developed a simple and reliable method of preserving antigen immunoreactivity with concomitant excellent retention of the cell ultrastructure. Using this method, we have been able to follow the origin and developmental stages of nuage accumulations within the nurse cell/oocyte syncytium in the ovary of the fru...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1145-2
更新日期:2011-04-01 00:00:00
abstract::The transient receptor potential (TRP) superfamily comprises a group of non-selective cation channels that have been implicated in both receptor and store-operated channel functions. The family of the classical TRPs (TRPCs) consists of seven members (TRPC1-7). The presence of TRPC1 and TRPC5 mRNA in the brain has prev...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0004-4
更新日期:2005-11-01 00:00:00
abstract::The neurosecretory cells of the ventral ganglia in the adult dragonfly, Orthetrum chrysis, are classified into A, B, C1 and C2 cells. The neurosecretory material in the ventral ganglia is composed of PAS-positive material with 1-, 2-glycol groups and some proteins. The proteins rich in cystine or cysteine occur predom...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221087
更新日期:1977-02-09 00:00:00
abstract::The octavo-lateral efferent system of several anuran species was studied by means of retrograde transport of horseradish peroxidase. This system is organized similarly in all larval anurans and in all adult aglossids. All have two groups of efferent neurons in the nucleus reticularis medialis between the VIIIth and th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214812
更新日期:1982-01-01 00:00:00
abstract::The dorsal integument of the girdle of the chiton Mopalia muscosa is covered by a chitinous cuticle about 0.1 mm in thickness. Within the cuticle are fusiform spicules composed of a central mass of pigment granules surrounded by a layer of calcium carbonate crystals. Tapered, curved chitinous hairs with a groove on th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221498
更新日期:1982-01-01 00:00:00
abstract::Among heterogeneous S100β-protein-positive (S100β-positive) cells, star-like cells with extended cytoplasmic processes, the so-called folliculo-stellate cells, envelop hormone-producing cells or interconnect homophilically in the anterior pituitary. S100β-positive cells are known, from immunohistochemistry, to emerge ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-015-2256-y
更新日期:2016-02-01 00:00:00
abstract::The development of the rat adrenal medulla was studied at the ultrastructural level with particular emphasis placed on early discrimination of different catecholamine-storing cells. The first granule-containing cells, phaeochromoblasts, were seen at day 15 of gestation migrating into the anlage of the cortex. These ce...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233834
更新日期:1981-01-01 00:00:00
abstract::Spinal cord injury (SCI) is a major cause of paralysis, disability and even death in severe cases. Lithium has neuroprotective effects on SCI, while the underlying mechanisms remain obscure. In the present study, we established a SCI rat model, which subsequently received lithium treatment. Results displayed that lith...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03298-3
更新日期:2021-01-19 00:00:00
abstract::The distribution of neuropeptide Y (NPY)-like immunoreactivity in the brain of the bichir, Polypterus senegalus, was examined immunohistochemically. NPY-like immunoreactivity was distributed widely in the brain, with the highest density in the diencephalon. NPY-positive perikarya were found in various areas, including...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050874
更新日期:1997-08-01 00:00:00
abstract::Two types of mitochondria-rich cells were found in the interplatelet areas of the gills of the migrating river lamprey. Both cell types are thought to be responsible for ion-transport across the gills. In the fresh-run migrant the gills are dominated by large, flask-shaped cells which show some ultrastructural similar...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221380
更新日期:1976-10-06 00:00:00
abstract::A striking feature of vestibular hair cells is the polarized arrangement of their stereocilia as the basis for their directional sensitivity. In mammals, each of the vestibular end organs is characterized by a distinct distribution of these polarized cells. We utilized the technique of post-fixation transganglionic ne...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-0944-1
更新日期:2010-05-01 00:00:00
abstract::Cyclooxygenase-2 (COX-2) is a recently discovered isoform of cyclooxygenase that is inducible by various types of inflammatory stimuli. Although this enzyme is considered to play a major role in inflammation processes by catalyzing the production of prostaglandins, the precise location, distribution, and regulation of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000296
更新日期:2001-02-01 00:00:00
abstract::Calcitonin receptor-immunoreactivity (CTR-ir) was found in enteric neurons of the mouse gastrointestinal tract from embryonic day 13.5 (E13.5) to post-natal day 28 (P28). CTR-ir occurred in cell bodies in ganglia of the myenteric plexus extending from the esophagus to the colon and in nerve cells of the submucosal gan...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1303-6
更新日期:2012-02-01 00:00:00
abstract::Haemophilic arthropathy is the major cause of disability in patients with haemophilia and, despite prophylaxis with coagulation factor concentrates, some patients still develop articular complications. We evaluate the feasibility of a tissue engineering approach to improve current clinical strategies for cartilage reg...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-016-2408-8
更新日期:2016-10-01 00:00:00
abstract::To investigate the mechanisms whereby bone cells absorb organic bone-matrix components during endochondral bone development, rat humeri were examined, employing horseradish peroxidase as a soluble protein tracer. Intravenously-injected peroxidase filled the osteoid layer and penetrated into the osteocyte lacunae and c...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219233
更新日期:1985-01-01 00:00:00
abstract::In mouse hepatocytes, the gap junctional proteins connexin32 (Cx32) and connexin26 (Cx26) are expressed in the same gap junctional plaque. Expression of the major Cx32 protein is downregulated during liver regeneration and cholestasis. Here we have analyzed the acute-phase response (after experimental inflammation) an...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000177
更新日期:2000-04-01 00:00:00
abstract::The periodontal ligament (PDL) is a highly specialized tissue connecting the cementum with the tooth socket bone and affects the life span of the tooth. However, little is known about the precise characteristics and regenerative mechanism of PDL cells because of the absence of specific markers and cell lines. Therefor...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0101-4
更新日期:2006-04-01 00:00:00
abstract::The diabetes (db/db) mutation (leptin-receptor defect) induces a hyperglycemic-hyperinsulinemic endometabolic environment that promotes hypercytolipidemic ovarian involution in C57BL/KsJ mice, resulting in reproductive sterility and eventual organoatrophy. The effectiveness of low-dose (1.0 microg/sc/3.5 day intervals...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0967-6
更新日期:2004-11-01 00:00:00
abstract::alpha-Smooth muscle (alpha SM) actin of endothermic vertebrates is selectively recognized by the monoclonal antibody anti-alpha SM-1. Immunoreactivity to this antibody has been shown to be localized in the NH2-terminal sequence Ac-EEED (Chaponnier et al. 1994). Among terrestrial ectothermic vertebrates, two amphibian ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00417867
更新日期:1995-09-01 00:00:00
abstract::Osteoarthritis (OA) is the most common joint disease with an unsatisfactory therapy outcome and characterized by the degradation of articular cartilage and synovial inflammation. Here, we isolated bone marrow mesenchymal stem cells (BMSCs) from rat's bone marrow and BMSC-derived exosome (BMSCs-Exo) from BMSCs successf...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03319-1
更新日期:2021-01-06 00:00:00
abstract::Human endothelial progenitor cells (EPCs) were isolated from cord blood samples and enriched by magnetic activated cell sorting method based on the CD133 marker. Cells were incubated with different doses of bacterial lipopolysaccharide, ranging from 2, 5, 10, 50, 100, 200, 250, 500, to 1000 µg/ml, for 48 h. The cell s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03405-4
更新日期:2021-01-18 00:00:00
abstract::Neuroblastoma cells grown on substrates in culture develop long processes and assume the morphology of normal neurons as judged light microscopically. The development of synapses in the cultured tissue is studied by periodic electron microscopic examination of the areas of contact between cells. The initial explants a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00232282
更新日期:1980-01-01 00:00:00
abstract::The fine structural organization of a cortical filament layer in normal locomoting Amoeba proteus was demonstrated using improved fixation and embedding techniques. Best results were obtained after application of PIPES-buffered glutaraldehyde in connection with substances known to prevent the depolymerization of F-act...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215699
更新日期:1982-01-01 00:00:00
abstract::The long nonmyelinated portion of the unipolar process of spinal ganglion cells resembles in many instances the perikaryon and is characterized by the following structural pecularities: 1. The surface membrane displays numerous invaginations and evaginations, which interdigitate with folds of the investing satellite c...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00222438
更新日期:1976-01-27 00:00:00
abstract::Parachlorophenylalanine (pCPA), an inhibitor of tryptophan hydroxylase which depletes brain serotonin in higher vertebrates, was injected into freshwater eels. After 4 or 6 injections (200 mg/kg/day) or 10 injections (100 and 140 mg/kg/day), the animals are paler, with a low melanophore index. In the pituitary gland, ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223217
更新日期:1978-07-13 00:00:00
abstract::The development of the heterophil granulocyte in the bone marrow of the rat is described, and an electron-microscopical analysis of the changes in the cytoplasm as well as in the granule population in several stages of maturation is reported. Three types of granule originate in consecutive stages of heterophil maturat...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00211466
更新日期:1983-01-01 00:00:00
abstract::Seven isoforms of tachykinin-related peptides (TRPs) have been isolated from the brain of the cockroach Leucophaea maderae. These peptides (LemTRP-1, 2, and 5-9) share the C-terminal sequence GFX(1)GX(2)Ramide (where X(1) and X(2) are variable residues). In order to determine the neuronal distribution of several of th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0538-7
更新日期:2002-05-01 00:00:00
abstract::Changes in intestinal function, notably impaired transit, following ischemia/reperfusion (I/R) injury are likely to derive, at least in part, from damage to the enteric nervous system. Currently, there is a lack of quantitative data and methods on which to base quantitation of changes that occur in enteric neurons. In...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-1126-x
更新日期:2011-04-01 00:00:00