Abstract:
:In the present study, we characterized intra-epithelial leukocytes in the digestive tract of chickens during postnatal development. Their phenotype was characterized by monoclonal antibodies in cryostat sections and the numbers of the different cell-types were counted in the epithelium of the esophagus, proventriculus, duodenum, jejunum, cecum, and colon. All intra-epithelial leukocytes bore the leukocyte-common antigen CD45; 35% were T lymphocytes, and 50% bore a B-cell marker. However, no immunoglobulin-bearing cells were detected in the epithelium. Monocytes and macrophages were found only in the epithelium of the esophagus. A remaining population of non-B, non-T, non-monocyte cells (15%) was present in all parts of the digestive tract. The number of intra-epithelial leukocytes was greatest in the duodenum and jejunum, and decreased in the proximal part of the cecum and in the colon. Intra-epithelial leukocytes were only sporadically detected in the proventriculus. The total number of intra-epithelial leukocytes increased until 8 weeks after hatching and then decreased at 18 months. In the esophagus, the total number of intra-epithelial leukocytes changed little during aging. We found that the intra-epithelial leukocytes of chickens and rodents are distinct in that chicken intra-epithelial leukocytes comprise a cell population that bears a B-cell antigen but that lacks surface immunoglobulins.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Vervelde L,Jeurissen SHdoi
10.1007/BF00318748subject
Has Abstractpub_date
1993-11-01 00:00:00pages
295-301issue
2eissn
0302-766Xissn
1432-0878journal_volume
274pub_type
杂志文章abstract::Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220534
更新日期:1977-10-21 00:00:00
abstract::This study explores the molecular composition of the tight junction (TJ) in human term placenta from normal women and from patients with preeclampsia, a hypertensive disorder of pregnancy. Maternal endothelial dysfunction is a critical characteristic of preeclampsia; hence, we have analyzed its impact on placental ves...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-005-0135-7
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abstract::The ultrastructure of immunoreactive somatotrophs and lactotrophs in pituitaries of fetal rats at 19, 20 and 21 days of gestation and on the day of birth was studied. Somatotrophs, first detectable at 19 days of gestation, undergo only minor modifications before reaching the structure described for adults. In particul...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00213955
更新日期:1986-01-01 00:00:00
abstract::The effects of the administration of thyroxine (T4) on the postnatal cytodifferentiation of granular convoluted tubule (GCT) cells of the submandibular gland (SMG) of Lewiss-Webster mice were studied by light and electron microscopy. From birth, mice of both sexes were injected daily with T4 (sc 0.4 micrograms/g BW) a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218202
更新日期:1987-05-01 00:00:00
abstract::The dental follicle is an ectomesenchymal tissue that surrounds developing tooth germ and that contains osteoblastic-lineage-committed stem/progenitor cells. We examined the osteogenic potential of human dental follicle cells (hDFC) by microarray analysis. We first compared the characteristics of hDFC with those of hu...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1477-6
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abstract::Morphologically the large intestine of the nutria resembles that of other caviomorphs, notably the guinea pig. The cecum is voluminous: it contributes 8.6% of the total intestinal length and 12.7% of the total intestinal surface area (considering the surface enlargement factor). It contains 27-32% of the wet ingesta a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214387
更新日期:1988-05-01 00:00:00
abstract::It is known that human and animal fibroblasts are able to induce the retraction of a fibrin clot. In the present study the correlation between (i) fibrin-fibroblasts during growth, (ii) the number of actin stress-lines in mouse fibroblasts during growth in culture, and (iii) the sensitivity of actin stress-lines to a ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218485
更新日期:1982-01-01 00:00:00
abstract::DNA distribution in mouse, rabbit and bull spermatids was analyzed by electron microscopy, after using a Feulgen-like HCl-osmium ammine procedure, and after immunocytochemistry with anti-DNA antibodies. In addition, nucleic acids were visualized with the intercalating dye ethidium bromide and phosphotungstic acid. The...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00340875
更新日期:1991-09-01 00:00:00
abstract::With the gallocyanine technique (Wittkowski, Bock and Franken, 1970) Gomori-positive substances of the infundibulum can be stained for light- and electron-microscopic examination. In various mammalian species, the size of Gomori-positive elementary granules in the outer layer is markedly different from that in the inn...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218495
更新日期:1975-11-19 00:00:00
abstract::Ionizing irradiation is an effective treatment for intracranial tumors but is limited by the potential adverse effects induced in surrounding normal brain. These effects can include cognitive impairments, and whereas the pathogenesis of such injury has not yet been definitively established, it may involve injury to th...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-007-0480-9
更新日期:2008-01-01 00:00:00
abstract::Placenta-derived stem cells (PDSCs) have gained interest as an alternative source of stem cells for regenerative medicine because of their potential for self-renewal and differentiation and their immunomodulatory properties. Although many studies have characterized various PDSCs biologically, the properties of the sel...
journal_title:Cell and tissue research
pub_type: 临床试验,杂志文章
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更新日期:2011-10-01 00:00:00
abstract::Pituitaries from normal, young and adult male rats were fixed either in sublimate-formalin or in glutaraldehyde-osmium. In adjacent Paraplast sections, almost all the gonadotrophs were immunostained with both LH and FSH antisera. The rat LH beta and FSH antisera used were shown to be highly specific by the absorption ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00233820
更新日期:1981-01-01 00:00:00
abstract::This study documents neuronal differentiation in vitro from undifferentiated precursor cells of caudalmost regenerating spinal cord of the teleost Apteronotus albifrons. At 11 days in vitro, cells from the caudalmost tip of the regenerating cord are flat and polygonal in shape, lack neuronal processes and do not stain...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00414166
更新日期:1994-11-01 00:00:00
abstract::Peeling skin syndrome is a heterogeneous group of rare disorders. Peeling skin, leukonychia, acral punctate keratoses, cheilitis and knuckle pads (PLACK syndrome, OMIM616295) is a newly described form of PSS with an autosomal recessive mode of inheritance. We report a 5.5-year-old boy with features of PLACK syndrome. ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-03077-9
更新日期:2019-11-01 00:00:00
abstract::The amniotic epithelium constitutes a diffusion barrier controlling the passage of solutes and water between the amniotic cavity and maternal circulation. With the present immunocytochemical approach, we have shown that several major components of the cyto-skeleton, i.e., actin, alpha-actinin, spectrin and ezrin, are ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318194
更新日期:1991-11-01 00:00:00
abstract::The etiologic basis of Parkinson's disease (PD), the second most common age-related neurodegenerative disorder, is unknown. Recent epidemiological and experimental studies indicate that exposure to environmental agents, including a number of agricultural chemicals, may contribute to the pathogenesis of this disorder. ...
journal_title:Cell and tissue research
pub_type: 杂志文章,评审
doi:10.1007/s00441-004-0937-z
更新日期:2004-10-01 00:00:00
abstract::Homeobox genes encode transcription factors that regulate embryonic development programs including organogenesis, axis formation and limb development. Previously, we identified and cloned a mouse double homeobox gene, Duxbl, whose homeodomain exhibits the highest identity (67 %) to human DUX4, a candidate gene of faci...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1974-x
更新日期:2014-11-01 00:00:00
abstract::The accessory medulla with its associated pigment-dispersing hormone-immunoreactive neurons appears to be the pacemaker that controls the circadian locomotor activity rhythm of the cockroach Leucophaea maderae. To permit studies at the level of individual, identified, pacemaker neurons, we developed specific long-term...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051324
更新日期:1999-06-01 00:00:00
abstract::Fc and C3 receptors, which are characteristically present on macrophages, could not be demonstrated on osteoclasts maintained in situ on their normal substrates when assayed for by use of sheep red blood cells coated with immunoglobulin (Shapiro et al. 1979). The present study tested the hypotheses that Fc receptors a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236514
更新日期:1980-01-01 00:00:00
abstract::Light microscopy of native preparations, histology, and electron microscopy have revealed that Phlebotomus duboscqi belongs to a class of sand fly species with prompt development of the peritrophic matrix (PM). Secretion of electron-lucent fibrils, presumably chitin, starts immediately after the ingestion of a blood m...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-009-0802-1
更新日期:2009-08-01 00:00:00
abstract::Changes in the frequency of endocrine cells are evidence of intestinal adaptation to germ-free (GF) status. Not only the distribution of these cells along the intestine, but also the differences in intracellular content of these regulatory peptides may be explored to explain functional and structural aspects of GF int...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000323
更新日期:2001-03-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章,评审
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更新日期:2015-09-01 00:00:00
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journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226673
更新日期:1977-11-30 00:00:00
abstract::Interstitial cells of Cajal (ICCs) are believed to be a major element in generating the spontaneous rhythm of the gastrointestinal tract. A prominent problem in the study of these cells has been the difficulty in observing them in intact tissues. We used the lipophilic dye DiI to stain ICCs in the submucosal-circular ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051058
更新日期:1998-05-01 00:00:00
abstract::Neural lobes of rats subjected to dehydration by drinking 2% saline for four days were examined electron microscopically and compared to untreated controls. The ultrastructure of the blood vessels and the tissues surrounding them were examined and it was found that, although few exocytotic figures could be seen in eit...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221710
更新日期:1975-06-24 00:00:00
abstract::The cellular response of non-neuronal elements of the pyramidal cell layer of the rat hippocampus, especially the area CA3, was observed electron microscopically following destruction of this formation by means of intraventricular administration of kainic acid (KA). The neuroglial cell types responding to the KA-induc...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00238652
更新日期:1981-01-01 00:00:00
abstract::This study provides information on the rates of DNA synthesis, sites of DNA synthesis, and DNA content of the avian salt gland during the osmotic stressing (plasma membrane synthesis) and destressing (plasma membrane turnover) cycle, in an effort to better understand the relationship of cell turnover to the initial ev...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214782
更新日期:1982-01-01 00:00:00
abstract::Low-temperature-embedded tissue of the subcommissural organ (SCO) of the rabbit was analyzed for the basal route of secretory product by means of indirect immuno-metal cytochemistry (protein A-gold technique) at the electron-microscopic level. By use of (1) an antiserum against bovine Reissner's fibre (see Sterba et a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219221
更新日期:1986-01-01 00:00:00
abstract::Thin sections after bile duct ligation showed that the depth of tight junctions appeared to increase and that the distance between individual punctate contacts appeared to become irregular and wider than in controls. The freeze fracture replicas clearly demonstrated these changes in the tight junction morphology. Chan...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236724
更新日期:1978-12-28 00:00:00
abstract::Collagens are the most abundant proteins in vertebrate tissues and constitute significant moieties of the extracellular matrix (ECM). The determination of the collagen content is of relevance not only in the field of native tissue research, but also regarding the quality assessment of bioengineered tissues. Here, we d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-010-1113-2
更新日期:2011-03-01 00:00:00