Immunocytochemical analysis of the cytoskeleton of the human amniotic epithelium.

Abstract:

:The amniotic epithelium constitutes a diffusion barrier controlling the passage of solutes and water between the amniotic cavity and maternal circulation. With the present immunocytochemical approach, we have shown that several major components of the cyto-skeleton, i.e., actin, alpha-actinin, spectrin and ezrin, are preferentially associated with the apical and lateral cell surfaces of the human amniotic epithelium. Keratins are distributed throughout the entire cytoplasm, whereas vimentin mainly forms a perinuclear scaffold. These findings indicate a role of the various components of the cytoskeleton in the structural integrity and modulation of cell shape and junctional permeability.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Wolf HJ,Schmidt W,Drenckhahn D

doi

10.1007/BF00318194

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

385-9

issue

2

eissn

0302-766X

issn

1432-0878

journal_volume

266

pub_type

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