Estrogen target cells in the pituitary of platyfish, Xiphophorus maculatus.

Abstract:

:The distribution of estradiol-concentrating cells in the pituitary of the platyfish, Xiphophorus maculatus, is studied after the injection of 3H estradiol-17 beta by thaw-mount autoradiography. Autoradiograms prepared 2-8 h after the injection show nuclear concentration of radioactivity in certain cells of the rostral pars distalis, pars intermedia and pars nervosa. Radioactively labeled cells are identified as gonadotropes by a combined technique of thaw-mount autoradiography and immunoperoxidase staining with antiserum to ovine LH. Approximately 80% of the immunoreactive LH cells show a concentration of radioactivity in their nuclei. These observations indicate that in teleosts, as in mammals, estradiol has a direct effect on pituitary gonadotropes.

journal_name

Cell Tissue Res

journal_title

Cell and tissue research

authors

Kim YS,Sar M,Stumpf WE

doi

10.1007/BF00234188

subject

Has Abstract

pub_date

1979-05-25 00:00:00

pages

435-40

issue

3

eissn

0302-766X

issn

1432-0878

journal_volume

198

pub_type

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