Abstract:
:Neurosecretory pathways were examined in normal male rats by the use of the immunoperoxidase technique for the localization of neurophysin in Bouin-fixed, deparaffinized sections. Using this technique two projections of extrahypothalamic neuorosecretory fibers can be traced to the sites of origin of the choid plexuses of both horns of the lateral ventricles. Neurophysin-containing axons originating primarily from the paraventricular field course dorsolaterad to enter the choroid fissure of the dorsal horn. A caudally direced group of fibers course ventrolaterad to enter the ventral horn choroid fissures. The supraoptic nuclear field is the primary contributor to the latter group. Scattered neurosecretory neurons are found in association with both pathways, usually in contact with blood vessels supplying the choroid plexuses, or in the telencephalic subependymal stroma. Neurosecretory fibers and terminals occur within the choroid fissures and juxtaventricular neuropil. The neurosecretory terminals in the choroid fissures appear as Herring-body type neurohemal organs; in the neuropil they appear as punctate peri-neuronal desities suggestive of synaptic contacts. Thes morphologic findings are discussed in relation to reports indicating the presence of antidiuretic, vasopressin-like activity in cerebrospinal fluid and choroid plexus extraxts together with ultrastructural evidence supportive of vasopressin-mediated transchoroidal cerebrospinal fluid absorption. These results and those of others indicated the possible involvement of the neurosecretory system in the regulation of brain interstitial-ventricular cerebrospinal fluid dynamics.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Brownfield MS,Kozlowski GPdoi
10.1007/BF00232829subject
Has Abstractpub_date
1977-03-01 00:00:00pages
111-27issue
1eissn
0302-766Xissn
1432-0878journal_volume
178pub_type
杂志文章abstract::The development of the heterophil granulocyte in the bone marrow of the rat is described, and an electron-microscopical analysis of the changes in the cytoplasm as well as in the granule population in several stages of maturation is reported. Three types of granule originate in consecutive stages of heterophil maturat...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00211466
更新日期:1983-01-01 00:00:00
abstract::Putative neural stem cells have been identified within the enteric nervous system (ENS) of adult rodents and cultured from human myenteric plexus. We conducted studies to identify neural stem cells or progenitor cells within the submucosa of adult human ENS. Jejunum tissue was removed from adult human subjects undergo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-011-1130-9
更新日期:2011-05-01 00:00:00
abstract::Homeobox genes encode transcription factors that regulate embryonic development programs including organogenesis, axis formation and limb development. Previously, we identified and cloned a mouse double homeobox gene, Duxbl, whose homeodomain exhibits the highest identity (67 %) to human DUX4, a candidate gene of faci...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-014-1974-x
更新日期:2014-11-01 00:00:00
abstract::The submandibular gland (SMG) of newborn mice has no mature acini but has the rudiments of acini called terminal tubules (TT). The TT are composed of TT cells with dark secretory granules and proacinar cells with lighter secretory granules, the latter being considered the immediate precursor of mature acinar cells. TT...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03205-w
更新日期:2020-08-01 00:00:00
abstract::This study aims to illustrate potential transport mechanisms behind the divergent approaches to nitrogen excretion seen in the ureotelic toadfish (Opsanus beta) and the ammoniotelic plainfin midshipman (Porichthys notatus). Specifically, we wish to confirm the expression of a urea transporter (UT), which is found in t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1591-0
更新日期:2013-06-01 00:00:00
abstract::Ontogenesis comprises a series of events including cell proliferation and apoptosis and resulting in the normal development of the embryo. Protein p53 has been described as being involved in the development of several animal species. The aim of this study was to analyze the expression of protein p53 during the morphog...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-013-1720-9
更新日期:2014-01-01 00:00:00
abstract::Blue-green fluorescent subependymal cells with intraventricular processes were shown by the fluorescent histochemical method to be distributed from the preoptic recess to the infundibular recess of the frog hypothalamus. Electron microscopy revealed at least two types of CSF-contacting subependymal cells, type 1 conta...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00221791
更新日期:1977-01-20 00:00:00
abstract::The regeneration of the vallate papilla in the rat was studied by both light and electron microscopy. The papillae were excised and regeneration was studied at time intervals of 3 to 45 days. It was found that the vallate papilla is capable of regeneration after both partial and total papillectomies. The regenerated p...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00225338
更新日期:1978-10-30 00:00:00
abstract::The distribution and development of growth-associated protein 43 (GAP-43)-like immunoreactivity (-LI) in the rat circumvallate papilla (CVP) were compared to those of protein gene product 9.5 (PGP 9.5)-LI. In the adult, thick GAP-43-like immunoreactive (-IR) structures gathered densely in the subgemmal region. Some of...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051142
更新日期:1998-09-01 00:00:00
abstract::Two different fixative procedures (immersion and perfusion) and four different fixative solutions were used in order to obtain the best preservation of the brush cells of the common bile duct of the rat. The results indicate that only perfusion fixation through the common bile duct is suitable, independent of the fixa...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00210353
更新日期:1981-01-01 00:00:00
abstract::Sections of glutaraldehyde-OsO4-fixed, plastic-embedded rat incisor enamel were left untreated, stained, decalcified (1% formic acid in 10% sodium citrate), or decalcified-stained. The presence of apatite crystals was monitored with electron diffraction. After brief decalcification and staining, apatite crystals and m...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215908
更新日期:1986-01-01 00:00:00
abstract::At the sites where a vein penetrates through the dura mater, two aspects deserve particular attention: (i) The delineation of the perivascular cleft, a space belonging to the interstitial cerebrospinal fluid (CSF) compartment, toward the interior hemal milieu of the dura mater. (ii) The relationship between the periva...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00214011
更新日期:1988-03-01 00:00:00
abstract::We previously demonstrated that GLUT2, a facilitated-diffusion glucose transporter isoform known to play critical roles in the regulation of systemic blood glucose level, is present at the apical ends of Müller cells in the rat retina. As a means of elucidating the ontogeny and possible role(s) of GLUT2 in the develop...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004419900099
更新日期:1999-11-01 00:00:00
abstract::Box jellyfish have the most elaborate sensory system and behavioural repertoire of all cnidarians. Sensory input largely comes from 24 eyes situated on four club-shaped sensory structures, the rhopalia, and behaviour includes obstacle avoidance, light shaft attractance and mating. To process the sensory input and conv...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0393-7
更新日期:2007-07-01 00:00:00
abstract::Dental caries is a chronic, infectious, and destructive disease that allows bacteria to break into the dental pulp tissue. As caries-related bacteria invade the human dentinal tubules, odontoblasts are the first line of dental pulp that trigger the initial inflammatory and immune responses. DNA methylation is a key ep...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-02993-0
更新日期:2019-06-01 00:00:00
abstract::The distribution of neuropeptide Y (NPY)-like immunoreactivity in the brain of the bichir, Polypterus senegalus, was examined immunohistochemically. NPY-like immunoreactivity was distributed widely in the brain, with the highest density in the diencephalon. NPY-positive perikarya were found in various areas, including...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050874
更新日期:1997-08-01 00:00:00
abstract::Previous studies have indicated the importance of basement membrane components both for cellular differentiation in general and for the barrier properties of cerebral microvascular endothelial cells in particular. Therefore, we have examined the expression of basement membrane proteins in primary capillary endothelial...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0604-1
更新日期:2002-10-01 00:00:00
abstract::Placing the clawed toad Xenopus laevis on a black background stimulates the melanotrope cells in the pars intermedia of the pituitary gland to release proopiomelanocortin (POMC)-derived peptides, including alpha-MSH and N-acetyl-beta-endorphin. In this study three types of secretory granules, electron-dense (approxima...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00314557
更新日期:1993-12-01 00:00:00
abstract::Using a somatostatin-gold conjugate of known biological activity, high affinity binding sites for this neuropeptide were visualized at cellular resolution on cultured diencephalic astrocytes and on frozen sections of the rat diencephalon. Binding could be completely suppressed in competition experiments with surplus u...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318767
更新日期:1991-02-01 00:00:00
abstract::Lysozyme is one of the most prominent antimicrobial peptides and has been identified from many mammalian species. However, this enzyme has not been studied in the order Insectivora, which includes the most primitive placental mammals. Here, we done the lysozyme cDNA from Suncus murinus (referred to as suncus, its labo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-019-02991-2
更新日期:2019-06-01 00:00:00
abstract::Mechanisms underlying the unique survival property of human spiral neurons are yet to be explored. P75 (p75(NTR)) is a low affinity receptor for neurotrophins and is known to interact with Trk receptors to modulate ligand binding and signaling. Up-regulation of this receptor was found to be associated with apoptosis a...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-012-1395-7
更新日期:2012-06-01 00:00:00
abstract::The distribution of Mg++-ATPase in osteoclasts along the endosteal surface of the chick tibia was investigated by neutral and alkaline pH cytochemical methods at the electron-microscopic level. Reaction product was observed in mitochondria, cytoplasmic vesicles, and ruffled-border membrane. Levamisole, ouabain, and va...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218550
更新日期:1986-01-01 00:00:00
abstract::The phase of primitive erythropoiesis in the feline yolk sac lasts from the 14th to the 20th day after malting. The globular nucleated primitive erythroblasts are formed extravascularly to some extent, but they can be clearly distinguished from the endoderm. They do not undergo a denucleation and are still present in ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219993
更新日期:1977-09-14 00:00:00
abstract::Interstitial cells of Cajal (ICC) are important regulatory cells in the smooth muscle coats of the digestive tract. Expression of the Kit receptor tyrosine kinase was used in this study as a marker to study their distribution and development in the striated musculature of the mouse esophagus. Sections and whole-mounts...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100418
更新日期:2001-10-01 00:00:00
abstract::We conducted an immunoelectron-microscopic study for histamine (HA) in the enterochromaffin-like (ECL) cells of normal rats and rats given alpha-fluoromethylhistidine (alpha-FMH, 3 mg/kg per hour) via osmotic minipumps over a period of 24 h. The indirect immunoperoxidase procedure utilized a mouse monoclonal antibody ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410100448
更新日期:2001-11-01 00:00:00
abstract::Effects of steroids on the accumulation of glycoprotein gonadotropin (GTH) in pituitaries of juvenile trout were investigated by means of scanning cytophotometry applied to immunocytochemical preparations, and with the use of a radioimmunoassay. Effects on other aspects of GTH-cell activity were analyzed by measuring ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226962
更新日期:1984-01-01 00:00:00
abstract::The ultrastructural localization of dipeptidyl peptidase IV (DPP IV) (EC 3.4.14.5) in rat submandibular and parotid glands was studied immunocytochemically by the peroxidase-antiperoxidase (PAP) method, using a monospecific antiserum against rat kidney DPP IV. There were no differences in the immunocytochemical locali...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00217869
更新日期:1984-01-01 00:00:00
abstract::Male germ cells of the greater bandicoot rat, Bandicota indica, have recently been categorized into 12 spermiogenic steps based upon the morphological appearance of the acrosome and nucleus and the cell shape. In the present study, we have found that, in the Golgi and cap phases, round spermatid nuclei contain 10-nm t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-008-0668-7
更新日期:2008-10-01 00:00:00
abstract::The retina of the distal and proximal lens-bearing complex ocelli are composed of pigmented sensory cells and long pigmented cells. A ciliary sheath from each sensory cell, together with the processes of long pigmented cells, extends through the vitreous layer as far as the capsule that envelops the lens. Each ciliary...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00219415
更新日期:1976-07-30 00:00:00
abstract::Tanycytes in the median eminence (ME) of the rat exhibit morphological features suggesting their possible participation in transport phenomena. After adrenalectomy, which modifies the hypothalamo-hypophyseal axis, they undergo morphological changes characterized by an accumulation of lipid droplets, an increased numbe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00215708
更新日期:1982-01-01 00:00:00