Abstract:
:Radiofrequency lesions were made in the lateral geniculate nuclei of six squirrel monkeys. The resulting degenerating terminals and their postsynaptic structures in layer IV of area 17 were quantitatively categorized on photomontages covering large areas of neuropil. Two to five days after the lesion, numerous axon terminals were affected by a variety of degenerative changes, i.e., enlargement and distortion of synaptic vesicles, neurofilamentous hyperplasia, electron-lucent and electron-dense reactions. Based on the aggregation of electron-dense material beneath the postsynaptic membrane, the degenerating terminals were considered to be of the asymmetric type. Among the degenerating boutons were the largest axon endings that occur in layer IV. Three days postoperatively, degenerating boutons contributed an average of 16.2% to the total synapse population; five days postoperatively, the average had increased to 19.3%. The percentage of degenerating boutons on individual montages, however, amounted to as much as 29%. This amount probably reflects more closely the actual contribution of the geniculocortical fiber system to layer IV of striate cortex. The postsynaptic structure most frequently contacted by degenerating axon endings was the dendritic spine, followed by dendrites of small diameter. To account for the diversity of degenerative changes in the same fiber system, we offer the tentative suggestion that heterogeneously degenerating axon terminals arise from a heterogeneous population of neurons in the lateral geniculate nucleus, i.e., from magnocellular versus parvocellular laminae.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Tigges M,Tigges Jdoi
10.1007/BF00234741keywords:
subject
Has Abstractpub_date
1979-02-28 00:00:00pages
471-86issue
3eissn
0302-766Xissn
1432-0878journal_volume
196pub_type
杂志文章abstract::Antisera to the neuropeptides corazonin (Crz) and crustacean cardioactive peptide (CCAP) and to the diapause hormone (DH) react with small sets of neurones in the cephalic ganglia of the crickets Dianemobius nigrofasciatus and Allonemobius allardi. The distribution of their immunoreactivities is similar in the two spe...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-006-0339-5
更新日期:2007-04-01 00:00:00
abstract::Dendritic cells are migratory cells. Before they extravasate from the circulation into the skin across capillary blood vessel walls, they have to interact with endothelial cells. Using a fluorimetric adhesion assay, we have recently shown that CD34(+)-derived dendritic cell precursors are able to bind to resting and s...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-003-0780-7
更新日期:2004-01-01 00:00:00
abstract::Bone resorption by mononucleated cells was studied in the acellular bone of a teleost fish (Oreochromis niloticus) by histological and enzyme histochemical observations and by transmission electron microscopy. Bone resorbing cells (osteoclasts) were identified by their location at the sites of bone resorption, their f...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050782
更新日期:1997-02-01 00:00:00
abstract::Thyroid glands of 7 to 21 day-old chick embryos were examined by electron microscopy using freeze-fracture and thin-section preparations. The primitive follicle lumen first appears between two adjacent epithelial cells in 8 day-old embryos, and is formed in the region of a focal tight junction (macula occludens). The ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00234830
更新日期:1979-04-30 00:00:00
abstract::Three types of sensilla occurring on the lips and on the antennae of Peripatopsis moseleyi have been investigated by scanning and transmission electron microscopy. On the lips sensory spines can be found which contain numerous cilia originating from bipolar receptor cells. They reach the tip of the spine where the cut...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220613
更新日期:1977-02-14 00:00:00
abstract::Marked changes in mice pubic symphysis occur by the end of pregnancy. Tissue remodeling involves a dynamic balance between cell proliferation and programmed cell death as well as changes in the extracellular matrix components. Therefore, it is important to consider both of these cellular behaviors when investigating t...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0463-x
更新日期:2007-10-01 00:00:00
abstract::Male rats kept on a standard diet were treated either with progesterone or testosterone by a single intramuscular injection of preparations which are slowly absorbed and metabolized. The rats were anaesthetized 24 h after application of the hormones, perfused with glutaraldehyde, and the parathyroid glands prepared fo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318797
更新日期:1992-05-01 00:00:00
abstract::Phenotype transition of vascular smooth muscle cells (VSMCs) is implicated in vascular diseases. Angiotensin-converting enzyme 2 (ACE2) is a perspective cardiovascular target due to its ability of converting angiotensin (Ang II) to Ang (1-7). Our group recently showed that ACE2 can regulate the function of endothelial...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-020-03259-w
更新日期:2020-12-01 00:00:00
abstract::Electron-dense granules (EDGs) are singular structures found in the tissues of several vertebrate and invertebrate organisms. Two types of EDGs were observed in hepatopancreatic cells of the crab Ucides cordatus: (1) a non-mineralized EDG, found mainly inside vacuoles, which reacted positively to acid phosphatase and ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0646-4
更新日期:2003-01-01 00:00:00
abstract::In the rostral hypothalamus of the domestic fowl, the magnocellular neurosecretory nuclei show a peculiar differentiation. Golgi studies of the supraoptic and paraventricular nuclei of the fowl reveal at least two major cell types: 1) large multipolar neurons, and 2) small interneurons. Golgi impregnations provide a d...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00236253
更新日期:1981-01-01 00:00:00
abstract::Intra-arterial injections of synthetic double-stranded RNA (polyinosinic:polycytidylic acid, PIPC) at a dose of 500 microg/kg evoked pronounced fever in guinea-pigs. PIPC-induced fever could be antagonized by treatment with the non-selective cyclooxygenase (COX) inhibitor diclofenac and was, in part, attenuated by the...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-007-0386-6
更新日期:2007-06-01 00:00:00
abstract::Brains and subesophageal ganglia from day 3.5 fifth stadium larvae of Manduca sexta were incubated in vitro with 4 nM tritiated ponasterone A, a 20-hydroxyecdysone analog, to determine whether uptake and specific binding of ecdysteroids occur at a cellular level. These tissues, which were taken just prior to the commi...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318414
更新日期:1991-01-01 00:00:00
abstract::Freeze-fracture replicas of the rat corpus callosum revealed prominent junctional strands in fractured cell membranes of the somata of oligodendrocytes. The junctional strands were characterized by an elaborate system of straight or slightly undulating rows of linear aggregates of particles or ridges in the P face and...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00220534
更新日期:1977-10-21 00:00:00
abstract::Calcitonin gene-related peptide (CGRP) was found extensively in the small intestine of both non-mammalian and mammalian vertebrates using radioimmunoassay and immunocytochemistry. By radioimmunoassay, the levels of CGRP in rats, mice, chickens, bullfrogs and rainbow trout were found to range from 91.5 to 419.1 ng/g ti...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223142
更新日期:1989-10-01 00:00:00
abstract::Purinoceptor subtypes were localised to various tissue types present within the nasal cavity of the rat, using immunohistochemical methods. P2X3 receptor immunoreactivity was localised in the primary olfactory neurones located both in the olfactory epithelium and vomeronasal organs (VNO) and also on subepithelial nerv...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0979-2
更新日期:2005-01-01 00:00:00
abstract::The morphology of the antennal hair-sensilla of Periplaneta americana, their distribution and frequency on the antennal flagellum have been examined by transmission- and scanning-electron microscopy. The types of sensilla were distinguished with respect to physiologically relevant criteria such as wall structure and n...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00223221
更新日期:1978-07-13 00:00:00
abstract::R*-cells of the digestive gland of Carcinus maenas have been investigated functionally and morphologically. A comparison of the capacity of separated cell suspensions to synthesize glycogen gave support to the hypothesis that R and R* cells belong to the same cell line. The unexpected observation of R* cells in gastri...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318696
更新日期:1992-01-01 00:00:00
abstract::The mole has a single pair of accessory sex organs with features of both the prostate and the seminal vesicle, for which the term prostate gland is not appropriate. Seasonal changes occuring in this gland were related to four periods: a) the quiescence period, b) the maturation period, c) the active period and d) the ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218718
更新日期:1976-12-10 00:00:00
abstract::Molting in shrimp is controlled by the molt-inhibiting hormone (MIH) and ecdysone. MIH inhibits the synthesis of ecdysone in the Y-organ, resulting in molt suppression; it is a neuropeptide member belonging to the eyestalk CHH/MIH/GIH family. The cloning of MIH (formerly MIH-like) of the shrimp Metapenaeus ensis has b...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410000299
更新日期:2001-01-01 00:00:00
abstract::To investigate the control of the timing in the epithelio-mesenchymal transformation of the neural crest into a migrating population, neural anlagen (neural tube plus crest) were isolated from 2-day quail embryos by proteases in the presence of CA++ and explanted onto substrates favourable for neural crest cell migrat...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00218011
更新日期:1985-01-01 00:00:00
abstract::Endothelial cells separate the intra- and extravascular space and regulate transport processes between these compartments. Since intercellular junctions are required for these specific cell functions, the cell-cell contacts in the permanent cell line ECV304 were systematically analyzed and compared with human umbilica...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410051340
更新日期:1999-07-01 00:00:00
abstract::The immunocytochemical localization of bovine oviduct-specific glycoproteins was investigated by light and electron microscopy. Using monoclonal antibodies (MAbs) specific for bovine oviductal glycoproteins, 3 regions (fimbriae, ampulla, and isthmus) of the epithelium in the bovine oviduct we studied during the follic...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00327983
更新日期:1993-10-01 00:00:00
abstract::In Syrian hamsters (Mesocricetus auratus), oxytocin (OXT) activity within the medial preoptic-anterior hypothalamus (MPOA-AH) and the ventromedial hypothalamus (VMH) plays an important role in the expression of sexual receptivity. Immunocytochemical analysis with OXT-specific antibodies was used to identify the distri...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s004410050993
更新日期:1998-02-01 00:00:00
abstract::Using isoenzyme-specific antisera, we have studied the distribution of protein kinase C isoforms in fetal mouse organs at the developmental age of 17 days. Two different sets of antibodies, produced by different manufacturers, were employed in this study. The specificity of the antisera was tested by immunoblotting ex...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00318364
更新日期:1995-06-01 00:00:00
abstract::The opioid peptide dynorphin A (1-17) is the third transmitter identified in the striatonigral projection, the other two being gamma-aminobutyric acid (GABA) and substance P. The ultrastructural features of the dynorphinergic terminals in substantia nigra/pars reticulata were studied using pre-embedding immunocytochem...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00329443
更新日期:1990-07-01 00:00:00
abstract::In an organ culture system under a three-dimensional microenvironment that provides the conditions needed for odontoblast differentiation, a row of odontoblasts can be induced (Kikuchi et al. 1996, 2001). Therefore, in a newly designed three-dimensional cell culture system that fulfils the conditions necessary for odo...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-004-0882-x
更新日期:2004-08-01 00:00:00
abstract::Our findings suggest that nitric oxide (NO) acts as peripheral neuromodulator in locusts, in which it is commonly co-localized with RF-like peptide in neurosecretory cells. We also present the first evidence for NO as a cardio-regulator in insects. Putative NO-producing neurones were detected in locust pre-genital fre...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-006-0188-2
更新日期:2006-08-01 00:00:00
abstract::Effects of steroids on the accumulation of glycoprotein gonadotropin (GTH) in pituitaries of juvenile trout were investigated by means of scanning cytophotometry applied to immunocytochemical preparations, and with the use of a radioimmunoassay. Effects on other aspects of GTH-cell activity were analyzed by measuring ...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226962
更新日期:1984-01-01 00:00:00
abstract::Intercellular communication between smooth muscle cells is crucial for contractile behaviour in normal and pathologically altered urinary bladder. Since the study of coupling is difficult in situ, we established cell cultures of bladder smooth muscle cells to analyse coupling mechanisms. Microinjection of Lucifer yell...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/s00441-002-0559-2
更新日期:2002-08-01 00:00:00
abstract::Rat blood monocytes contain granules of two types, primary and secondary granules, which can be distinguished on morphological grounds. Secondary granules have a halo between the limiting membrane and the matrix; primary granules have no halo and are generally more elongate than the secondary granules. In addition, th...
journal_title:Cell and tissue research
pub_type: 杂志文章
doi:10.1007/BF00226665
更新日期:1977-11-30 00:00:00