Abstract：
:The problem of the blood-brain barrier in the pineal organ of the rainbow trout, Salmo gairdneri, was investigated following intraperitoneal or intracardial injections of several tracers and dyes with different molecular weights. As demonstrated at the light-microscopic level, repeated injections of trypan blue or horseradish peroxidase (HRP) resulted in an accumulation of these substances in the pineal epithelium (parenchyma). By use of the electron microscope, HRP was found in electron-dense bodies, probably lysosomes, in the endothelial cells and perivascular macrophages 4 h after intraperitoneal injection, the supporting cells and intrapineal or luminal macrophages 8 h after injection, and the receptor cells 24 h after injection of the tracer. Ferritin particles penetrated the fenestrated endothelium of pineal capillaries. They were confirmed to vesicles, vacuoles and the smooth endoplasmic reticulum of the supporting cells as well as to the synaptic vesicles and the smooth endoplasmic reticulum of the pineal photoreceptors. The intercellular passage of tannic acid mixed with the fixative was blocked at the luminal junctional complex separating the pineal lumen from the basal portion of the pineal epithelium. The passive intercellular transport of substances with high molecular weight from the bloodstream to the cerebrospinal-fluid compartment is thus prevented. However, no blood-brain barrier exists for exogenously administered proteins, which are rapidly taken up by pineal cells and actively transported in a transcellular manner. The findings on the blood-brain barrier of the pineal organ of the rainbow trout are discussed with particular reference to the endocrine capacity of pineal sensory organs.
journal_name
Cell Tissue Resjournal_title
Cell and tissue researchauthors
Omura Y,Korf HW,Oksche Adoi
10.1007/BF00219238subject
Has Abstractpub_date
1985-01-01 00:00:00pages
599-610issue
3eissn
0302-766Xissn
1432-0878journal_volume
239pub_type
杂志文章abstract：:Caprine preantral follicles within ovarian fragments were cryopreserved in the absence or presence of 0.5 M sucrose with or without 1 M dimethyl sulfoxide and/or 1 M ethylene glycol (EG). After being thawed, they were washed in minimum essential medium with or without 0.3 M sucrose. Histological analysis of follicle i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-006-0193-5
更新日期：2006-09-01 00:00:00
abstract：:Inside the light organs of the bioluminescent (light-producing) crustacean Meganyctiphanes norvegica (krill), numerous capillaries drain haemolymph into the light-producing structure (lantern). We have investigated the arrangement and function of filamentous material found around the opening of the capillaries. These ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-009-0774-1
更新日期：2009-05-01 00:00:00
abstract：:Activities of the H+, K(+)-ATPase and the Na+, K+, ATPase have been localized in the morphologically heterogeneous oxyntic cell lineage of adult bovine abomasal mucosa, by means of K(+)-dependent paranitrophenylphosphatase (K(+)-pNPPase) histochemistry. At the light- and electron-microscopic level, only members of the...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050583
更新日期：1996-05-01 00:00:00
abstract：:Brain injuries trigger physiological reactions which are mediated by a number of cytokines including interleukin-6 (IL-6), ciliary neurotrophic factor (CNTF), and leukemia inhibitory factor (LIF). Astrocytes and microglia, the protagonists in these traumatic responses, are known to secrete a variety of paracrine signa...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-002-0624-x
更新日期：2002-11-01 00:00:00
abstract：:Perinatal changes in the appearance of intramembranous particles (IMPs) of microvilli of enterocytes were analyzed quantitatively. In both the jejunum and the ileum, the IMP density on the P-face showed no significant changes from day 17 of gestation to day 5 of postnatal life. It increased between day 5 and day 12, r...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00212224
更新日期：1983-01-01 00:00:00
abstract：:Transforming growth factor beta (TGF-beta) is a major member of a cytokine family with pluripotent biological activity. In the liver, TGF-beta has pathophysiological significance with respect to hepatic fibrogenesis, regulation of liver cell growth, tumor development, and induction of hepatocellular apoptosis. We show...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410050740
更新日期：1997-01-01 00:00:00
abstract：:The olfactory epithelium of mice after axotomy was investigated to clarify the stem cells of olfactory cells by double immunostaining using antikeratin (MA903) and anti-bromodeoxyuridine (BrdU) antibodies and by conventional electron microscopy. When a single dose of BrdU was given to mice 9 days after axotomy, immuno...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318179
更新日期：1991-11-01 00:00:00
abstract：:The distribution of Mg++-ATPase in osteoclasts along the endosteal surface of the chick tibia was investigated by neutral and alkaline pH cytochemical methods at the electron-microscopic level. Reaction product was observed in mitochondria, cytoplasmic vesicles, and ruffled-border membrane. Levamisole, ouabain, and va...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218550
更新日期：1986-01-01 00:00:00
abstract：:Satellite cells can be isolated from skeletal muscle biopsies, activated to proliferating myoblasts and differentiated into multinuclear myotubes in culture. These cell cultures represent a model system for intact human skeletal muscle and can be modulated ex vivo. The advantages of this system are that the most relev...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-013-1655-1
更新日期：2013-12-01 00:00:00
abstract：:In the corpuscles of Stannius of sticklebacks and eels two cell types are described of presumably endocrine nature. The predominating type, comparable to the cells observed in other species, responds to variation in calcium content of the medium and possibly produces a hypocalcemic hormone. The second cell type is unr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00219163
更新日期：1975-06-09 00:00:00
abstract：:The fine structure of the main excretory duct epithelium (MEDE) of female mouse submandibular gland was investigated by scanning and transmission electron microscopy and the results compared with the previously established structure of male mouse MEDE. A comparative analysis of the subepithelial capillaries of both se...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00300213
更新日期：1994-09-01 00:00:00
abstract：:The freshwater polyp Hydra magnipapillata has a primitive nervous system that produces at least three distinct classes of neuropeptides: various peptides having the C-terminal sequence Arg-Phe-NH2 (the Hydra-RFamide family), Leu-Trp-NH2 (the Hydra-LWamide family), and a single peptide having the C-terminal sequence Ly...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000240
更新日期：2000-08-01 00:00:00
abstract：:Rhabdomeres of the Drosophila melanogaster canoemisl mutant ommatidia were twisted, branched, and often fused to each other. A considerable proportion of rhabdomeres were found to have fallen below the retinal basement membrane. Electron-microscopic observations of the mutant ommatidia revealed that microvilli, the su...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004419900107
更新日期：1999-12-01 00:00:00
abstract：:The ultrastructure of crystalline beta granules of the islets of Langerhans in the alligator has been investigated. From optical diffraction analysis and serial sectioning, the existence of four distinct types of crystalline inclusions was established in ultrathin sections. The first type is the most frequent and is i...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00229618
更新日期：1978-03-13 00:00:00
abstract：:Methods for isolation and culture of microvascular endothelial cells of the inner ear were devised to provide an in-vitro system for studying endothelial functions in this tissue. Capillaries from the stria vascularis and spiral ligament were treated enzymatically to free them from surrounding tissue. Contamination by...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00214566
更新日期：1985-01-01 00:00:00
abstract：:The choroid plexus from the lateral ventricles of 18-day chick embryos was cultivated as an organ in medium 199 until the degeneration of the stroma. Selected plexuses forming an empty epithelial sac were then incubated with enzyme-treated human immunoglobulin (5S-antibody) and with native human immunoglobulin (7S-ant...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00237886
更新日期：1980-01-01 00:00:00
abstract：:The long nonmyelinated portion of the unipolar process of spinal ganglion cells resembles in many instances the perikaryon and is characterized by the following structural pecularities: 1. The surface membrane displays numerous invaginations and evaginations, which interdigitate with folds of the investing satellite c...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00222438
更新日期：1976-01-27 00:00:00
abstract：:Maturing erythroblasts and erythrocytes were studied in chickens and adult hens to provide more information on the presence and frequency of various nucleolar types in these cells. Nucleoli were present at all stages of erythroblastic and erythrocytic development except in the case of a few reticulocytes and the matur...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00209211
更新日期：1975-09-17 00:00:00
abstract：:The burrower bug Scaptocoris castanea is an important soybean and pasture pest in Brazil, with an underground habit feeding directly on the sap of the roots. Underground habit hinders control and knowledge of the biology and physiology of this pest. This study describes the anatomy, histology, ultrastructure and symbi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03197-7
更新日期：2020-11-01 00:00:00
abstract：:Numerous nerve fibres containing acetylcholinesterase and noradrenaline, as well as avian pancreatic polypeptide-, vasoactive intestinal peptide-, or substance P-like immunoreactivity are observed around arteries in the external carotid rete of the cat. The nerves are located in the adventitial layer close to the medi...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00218360
更新日期：1982-01-01 00:00:00
abstract：:This review focuses on the signaling system involving the Angiopoietin1/Tie2 receptor, which appears to be involved in the secondary stages of blood vessel formation. Although this system is crucial for blood and lymphatic vessel formation, identifying its precise role in embryonic and adult vascular biology has been ...
journal_title：Cell and tissue research
pub_type： 杂志文章,评审
doi：10.1007/s00441-003-0749-6
更新日期：2003-10-01 00:00:00
abstract：:The origin of cobblestone-like polygonal cells (the most numerous in renal glomerular cell culture) remains controversial; they could be either dedifferentiated podocytes or parietal epithelial cells (PECs) of Bowman's capsule. Poor cellular outgrowth from glomeruli devoid of Bowman's capsule (decapsulated glomeruli) ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410100380
更新日期：2001-06-01 00:00:00
abstract：:Cells binding anti-bovine TASH beta serum were found exclusively in the rostral lobe of the adenohypophysis of the drake using the peroxidase-antiperoxidase complex unlabelled antibody method. The specificity of the binding of the anti-serum to TSH cells was established by relating the morphology and relative abundanc...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00234834
更新日期：1979-04-30 00:00:00
abstract：:In three species of teleosts - carp Cyprinus carpio; grass carp Ctenopharyngodon idella; and crucian carp Carassius auratus - the caudal neurosecretory system displays small, medium-sized and large neurons. Urotensin I (UI)-immunoreactive and UI-nonreactive neurons were found in all three groups; in general, the numbe...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00212550
更新日期：1986-01-01 00:00:00
abstract：:The position, structure and function of the valves within the lateral sinus of the medical leech, Hirudo medicinalis, are described on the basis of vital, light- and electron microscopy. In this species the valvular apparatus consists of multiple elongated fir cone-shaped fibrous villi surrounding the orifices of the ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00399522
更新日期：1976-09-20 00:00:00
abstract：:In the central nervous system, serotonergic and dopaminergic signaling is terminated by the activity of specialized transporter proteins for serotonin (SERT) and dopamine (DAT). These transporter proteins are found both on the cell surface and in intracellular transport vesicles. Trafficking between these subcellular ...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-011-1256-9
更新日期：2011-11-01 00:00:00
abstract：:The medial preoptic nucleus is a sexually dimorphic structure whose cytoarchitecture, afferent and efferent connections, and functions have been previously described. No detailed ultrastructural study has, however, been performed to date. Here we describe the ultrastructural organization of this important preoptic str...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00318164
更新日期：1995-03-01 00:00:00
abstract：:Post-translational glycosylation of proteins with O-linked β-N-acetylglucosamine (O-GlcNAcylation) and changes of galectin expression profiles are essential in many cellular stress responses. We examine this regulation in the liver tissue of hibernating thirteen-lined ground squirrels (Ictidomys tridecemlineatus) repr...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s00441-020-03185-x
更新日期：2020-07-01 00:00:00
abstract：:In recent years, data have accumulated suggesting that the role of neurotrophins and Trk receptors may not be limited to the nervous system, and the presence of these substances has been detected in a variety of vertebrate and invertebrate non-nervous tissues. This study was designed to map the expression of immunorea...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/s004410000181
更新日期：2000-04-01 00:00:00
abstract：:The fine structural organization of a cortical filament layer in normal locomoting Amoeba proteus was demonstrated using improved fixation and embedding techniques. Best results were obtained after application of PIPES-buffered glutaraldehyde in connection with substances known to prevent the depolymerization of F-act...
journal_title：Cell and tissue research
pub_type： 杂志文章
doi：10.1007/BF00215699
更新日期：1982-01-01 00:00:00
