Dendritic development in the neocortex of adult rats following a maintained prenatal and/or early postnatal life undernutrition.

Abstract:

:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alterations consist of a decrease in the number and span of dendritic basilar processes of large pyramidal cells. In animals malnourished during prenatal life and the suckling period the reduction of the basal dendritic arborization was more apparent. It is postulated that the vulnerable period for the basal dendritic development occupies the period from the end of pregnancy until the first 3 wk of postnatal life in the rat (suckling period). Noxious influences acting during this phase induce sequelae that cannot be reversed by subsequent refeeding. A maintained nutritional insult during prenatal and early postnatal life induces the most severe changes in dendritic arborizations, compared to those resulting from a prolonged postnatal malnutrition.

journal_name

Early Hum Dev

journal_title

Early human development

authors

Cordero ME,Trejo M,García E,Barros T,Rojas AM,Colombo M

doi

10.1016/0378-3782(86)90186-6

subject

Has Abstract

pub_date

1986-12-01 00:00:00

pages

245-58

issue

3-4

eissn

0378-3782

issn

1872-6232

pii

0378-3782(86)90186-6

journal_volume

14

pub_type

杂志文章
  • Association of fetal and maternal carboxyhemoglobin levels in normal and Rh-alloimmune pregnancies.

    abstract:OBJECTIVE:To compare paired antepartum fetal/maternal COHb ratios in whole blood from control and alloimmunized pregnancies and to examine the relationships between fetal and maternal COHb. METHODS:COHb levels were measured in paired fetal and maternal blood samples obtained at cordocentesis in 47 control and 16 Rh-al...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(00)00079-7

    authors: Hayde M,Pollak A,Bernaschek G,Weiner CP,Vreman HJ,Stevenson DK,Widness JA

    更新日期:2000-06-01 00:00:00

  • Brain functional network connectivity development in very preterm infants: The first six months.

    abstract::Nearly 10% of premature infants are born very preterm at 32weeks gestational age or less in the United States. Up to 35% of these very preterm survivors are at risk for cognitive and behavioral deficits. Yet accurate diagnosis of such deficits cannot be made until early childhood. Resting-state fMRI provides noninvasi...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2016.06.002

    authors: He L,Parikh NA

    更新日期:2016-07-01 00:00:00

  • Zinc deficiency: a problem with preterm breast milk.

    abstract::We report a breast-fed preterm infant (31 weeks gestation) who developed nutritional zinc deficiency 13 weeks post delivery. Serial samples of his mothers breast milk from early lactation (2 weeks post delivery) contained very low zinc concentrations, although her serum zinc and sweat zinc concentrations were normal. ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(85)90062-3

    authors: Murphy JF,Gray OP,Rendall JR,Hann S

    更新日期:1985-01-01 00:00:00

  • The functional effects of nutrients on enterocyte proliferation and intestinal ion transport in early infancy.

    abstract::Nutrition has a key role in the modulation of the developing intestine in early infancy, and nutrients are able to modulate several intestinal functions including nutrient absorption, ion transport, cell growth and differentiation, motility and immunomodulation. Such modulation is exerted in part through a direct inte...

    journal_title:Early human development

    pub_type: 杂志文章,评审

    doi:10.1016/j.earlhumdev.2010.01.008

    authors: Buccigrossi V,Giannattasio A,Armellino C,Lo Vecchio A,Caiazzo MA,Guarino A

    更新日期:2010-07-01 00:00:00

  • The association of the cerebral oxygenation during neonatal sepsis with the Bayley-III Scale of Infant and Toddler Development index scores at 18-24 months of age.

    abstract:BACKGROUND:Neonatal sepsis has been associated with poor neurodevelopmental outcome, however the evidence regarding the exact mechanism of the inflammation to the developing neonatal brain are inconclusive. AIMS:To investigate association between cerebral oxygenation during neonatal sepsis and neurodevelopmental outco...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2019.07.008

    authors: Rallis D,Karagianni P,Goutsiou E,Soubasi-Griva V,Banerjee J,Tsakalidis C

    更新日期:2019-09-01 00:00:00

  • Motor-function and exercise capacity in children with major anatomical congenital anomalies: an evaluation at 5 years of age.

    abstract:BACKGROUND:Children with major anatomical congenital anomalies (CA) often need prolonged hospitalization with surgical interventions in the neonatal period and thereafter. Better intensive care treatment has reduced mortality rates, but at the cost of more morbidity. AIM:To study motor-function and exercise capacity i...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2010.06.014

    authors: van der Cammen-van Zijp MH,Gischler SJ,Mazer P,van Dijk M,Tibboel D,Ijsselstijn H

    更新日期:2010-08-01 00:00:00

  • Inflating pressures for effective resuscitation of preterm infants.

    abstract::The magnitude of inflating pressure necessary for effective resuscitation was examined in 70 preterm infants. The median pressure to cause adequate chest wall expansion was 22.8 cmH2O; no infant required a peak inflating pressure greater than 30 cmH2O. No further increase in inflation pressure was used during resuscit...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(91)90045-5

    authors: Hird MF,Greenough A,Gamsu HR

    更新日期:1991-07-01 00:00:00

  • Movement analysis in neonates with spina bifida aperta.

    abstract:INTRODUCTION:In neonates with spina bifida aperta (SBA), leg movements by myotomes caudal to the meningomyelocele (MMC) are transiently observed. It is unclear whether these leg movements relate to functional neural conduction through the MMC. For optimal therapeutical intervention, pathophysiological insight in these ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2005.09.002

    authors: Sival DA,Brouwer OF,Bruggink JL,Vles JS,Staal-Schreinemachers AL,Sollie KM,Sauer PJ,Bos AF

    更新日期:2006-04-01 00:00:00

  • Fluconazole prophylaxis in preterm infants: a multicenter case-controlled analysis of efficacy and safety.

    abstract:BACKGROUND:Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS:We conducted a case-co...

    journal_title:Early human development

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0378-3782(14)70026-X

    authors: Kaufman DA,Morris A,Gurka MJ,Kapik B,Hetherington S

    更新日期:2014-03-01 00:00:00

  • Early human development: neonatal tumours: vascular tumours.

    abstract::Vascular tumours (haemangiomas and malformations) are common tumours of infancy and childhood. They represent a group of mostly benign conditions, which present early, can grow rapidly and be symptomatic or disfiguring. There are various management options, with different cosmetic and functional outcomes. Haemangiomas...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2010.08.017

    authors: McHoney M

    更新日期:2010-10-01 00:00:00

  • COVID-19: Combined supply-side and demand-side shocks, so lift restrictions (carefully) lest GPD declines ultimately kill more than COVID-19.

    abstract::COVID-19 remains pandemic. Social distancing and travel restrictions have avoided countless deaths and infections but disrupted livelihoods and economies. The global loss of gross (world) product is unprecedented as COVID-19 has inflicted both a supply-side and a demand-side shock. While public health measures have mi...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2020.105209

    authors: Grech V,Grech P

    更新日期:2020-10-01 00:00:00

  • Fetal growth retardation as a cause of impaired ovarian development.

    abstract::Low birthweight has been associated with diseases and disorders later in life. It has been suggested that this is caused by the impaired development of abdominal organs, especially in cases of growth retardation. Besides general malnutrition of the fetus, preferential bloodflow to the heart and brain may further depri...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(97)00073-x

    authors: de Bruin JP,Dorland M,Bruinse HW,Spliet W,Nikkels PG,Te Velde ER

    更新日期:1998-04-17 00:00:00

  • Early visual and neuro-development in preterm infants with and without retinopathy.

    abstract:BACKGROUND:Retinopathy of prematurity (ROP) is often associated with visual impairment and multiple developmental disabilities. AIMS:As most of the previous studies include infants with brain lesions, that can determine visual impairment per se, a cohort of low neurological risk preterm infants without ROP and with va...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2020.105134

    authors: Ricci D,Lucibello S,Orazi L,Gallini F,Staccioli S,Serrao F,Olivieri G,Quintiliani M,Sivo S,Rossi V,Leone D,Ferrantini G,Romeo DM,Frezza S,Amorelli GM,Molle F,Vento G,Lepore D,Mercuri E

    更新日期:2020-09-01 00:00:00

  • Spectrum of hypermethioninemia in neonatal screening.

    abstract::Measurement of methionine levels in dried blood spots has been one of the items of neonatal screening in Taiwan for more than 20 years. In 1,701,591 newborns, 17 cases of hypermethioninemia were detected, but among them only one had homocystinuria. More than half of the 16 cases of isolated hypermethioninemia had muta...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2004.11.005

    authors: Chien YH,Chiang SC,Huang A,Hwu WL

    更新日期:2005-06-01 00:00:00

  • Experimental intrauterine growth retardation in the rat. Evaluation of the Wigglesworth model.

    abstract::The validity of the Wigglesworth experimental model to produce newborn rats that are small for gestational age by ligation of one of both uterine vessels was confirmed. Newborn rats from the opposite horns are used as controls in the classical model. It is concluded from this study that newborns from sham-operated dam...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(79)90038-0

    authors: Kollée LA,Monnens LA,Trijbels JM,Veerkamp JH,Janssen AJ

    更新日期:1979-09-01 00:00:00

  • The use of oxygen for delivery room resuscitation of newborn infants in non-Western countries.

    abstract:BACKGROUND:Using pure oxygen (PO) in neonatal resuscitation increases oxidative stress and mortality in full-term hypoxic infants. International neonatal resuscitation guidelines recommend air or blended oxygen for resuscitation regardless of gestational age but this requires education and equipment that may not be glo...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2012.01.005

    authors: Koh J,Yeo CL,Wright I,Lui K,Saugstad O,Tarnow-Mordi W,Smyth J,Oei JL

    更新日期:2012-08-01 00:00:00

  • Cystic periventricular leukomalacia in preterm infants: an analysis of obstetric risk factors.

    abstract:OBJECTIVE:To identify obstetric risk factors and to elucidate the effect of prolonged rupture of the membranes on the development of cystic periventricular leukomalacia (PVL) in preterm infants. METHODS:A retrospective case-control study of 95 preterm infants with the diagnosis of PVL and 245 healthy controls matched ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2008.07.007

    authors: Bauer M,Fast C,Haas J,Resch B,Lang U,Pertl B

    更新日期:2009-03-01 00:00:00

  • Transthyretin levels are not related to Apgar score in low birth weight and very low birth weight infants.

    abstract:BACKGROUND:Previous studies have reported an increased incidence of thyroid dysfunction in premature/low birth weight infants. The cord blood concentrations of transthyretin (TTR), a thyroid hormone binding protein, have also been found to be decreased in preterm infants. While thyroid hormone concentrations are decrea...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2008.01.001

    authors: Su PH,Wang SL,Chen JY,Hu JM,Chang HP,Chen SJ

    更新日期:2008-08-01 00:00:00

  • Fetal inflammatory response in second trimester candidal chorioamnionitis.

    abstract::Candidal chorioamnionitis is an uncommon and apparently rather indolent intrauterine infection in which the fetus is able to marshal some of the immunological forces at its disposal against an easily visualized antigen impinging on lung mucosal surfaces. In a retrospective histological study of one of the largest repo...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(85)90113-6

    authors: Hood IC,Browning D,de Sa DJ,Whyte RK

    更新日期:1985-05-01 00:00:00

  • Does breast feeding protect against non-gastric infections?

    abstract::There is convincing evidence that breast-feeding is protective against gastro-enteritis and diarrhoea, but for other infections the situation is less clear cut. There is evidence that breast-fed infants are at increased risk of one infection (infant botulism). They are probably not significantly protected from upper r...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(97)00056-x

    authors: Golding J,Emmett PM,Rogers IS

    更新日期:1997-10-29 00:00:00

  • Structured observation of motor performance (SOMP-I) applied to neonatally healthy fullterm infants at the ages of 0-10 months.

    abstract::A new protocol for structured observation of motor performance in infants, SOMP-I, was applied to 72 neonatally healthy fullterm infants at 0, 2, 4, 6 and 10 months of age. It contains 13 items, formed as ascending scales, consisting of detailed descriptions of motor performance in different body positions and body pa...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(94)01598-J

    authors: Persson K,Strömberg B

    更新日期:1995-01-30 00:00:00

  • Prenatal diagnosis of trisomy 21 through detection of trophoblasts in cervical smears.

    abstract:BACKGROUND:Fetal cells exfoliate in the uterine cavity during early pregnancy and are a potential source of material for NIPD. AIMS:This study was designed to test the hypothesis that fetal cells obtained from the uterine cervix during the first trimester of pregnancy could be utilized for prenatal diagnosis of chromo...

    journal_title:Early human development

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.earlhumdev.2010.04.005

    authors: Sifakis S,Ghatpande S,Seppo A,Kilpatrick MW,Tafas T,Tsipouras P,Fejgin M,Amiel A

    更新日期:2010-05-01 00:00:00

  • Global perfusion assessment and tissue oxygen saturation in preterm infants: where are we?

    abstract::Near infrared spectroscopy (NIRS) monitoring is a new challenge for clinicians who deal with early detection of dangerous hypoperfusion in the brain, as well as in splanchnic and renal districts in critically ill preterm infants. Previous studies performed on infants and children with congenital heart disease, demonst...

    journal_title:Early human development

    pub_type: 杂志文章,评审

    doi:10.1016/S0378-3782(13)70014-8

    authors: Cerbo RM,Maragliano R,Pozzi M,Strocchio L,Mostert M,Manzoni P,Stronati M

    更新日期:2013-06-01 00:00:00

  • The association between cord pH at birth and intellectual function in childhood.

    abstract:BACKGROUND:Acidemia at birth is very common but little is known about its long-term consequences. AIM:To determine if pH at birth is related to established tests of intellectual function. SUBJECTS:School children aged 6-8, for whom obstetric data were available, who had been delivered after labour at term, and had an...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2007.02.002

    authors: Svirko E,Mellanby J,Impey L

    更新日期:2008-01-01 00:00:00

  • Effect of antenatal corticosteroids on postmortem brain weight of preterm babies.

    abstract:OBJECTIVES:To investigate the effects of single and repeated courses of antenatal corticosteroids on brain growth in very preterm babies. DESIGN:Retrospective study of 110 very preterm babies delivered at a single University Teaching Hospital between 1992 and 1999 who had a full necropsy including detailed examination...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(01)00144-x

    authors: Murphy DJ

    更新日期:2001-07-01 00:00:00

  • The effect of lactational mastitis on the macronutrient content of breast milk.

    abstract:AIMS:Mastitis in lactating mothers reduces milk production and alters the cellular composition of milk. Changes occurring in the mammary gland during the inflammatory response are believed to increase the permeability of the blood-milk barrier. This study examined the effect of mastitis during lactation on the macronut...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2016.03.009

    authors: Say B,Dizdar EA,Degirmencioglu H,Uras N,Sari FN,Oguz S,Canpolat FE

    更新日期:2016-07-01 00:00:00

  • Attention capacities of preterm and term born toddlers: A multi-method approach.

    abstract:OBJECTIVE:Many preterm children show difficulties in attention at (pre)school age. The development of attention capacities of preterm and term toddlers was compared using a longitudinal and multi-method approach at 12, 18 and 24months. METHOD:Attention was measured for 123 preterm (32-36weeks gestation) and 101 term b...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2015.08.015

    authors: de Jong M,Verhoeven M,van Baar AL

    更新日期:2015-12-01 00:00:00

  • Role of myoinositol in regulation of surfactant phospholipids in the newborn.

    abstract::According to animal studies myoinositol decreases surfactant phosphatidylglycerol and increases phosphatidylinositol. In the present study lung effluent phospholipids and serum myoinositol were analyzed in respiratory distress syndrome (RDS, 19 cases), in other lung disease (6 cases) and in 22 newborn with no lung dis...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(85)90055-6

    authors: Hallman M,Saugstad OD,Porreco RP,Epstein BL,Gluck L

    更新日期:1985-01-01 00:00:00

  • Sirenomelia in a twelve weeks abortus.

    abstract::The anatomical findings of sirenomelia in a 12-weeks aborted embryo are reported. The occurrence of sirenomelia in material from spontaneous abortions is discussed. ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(87)90080-6

    authors: Malinger G,Treschan O,Rosen N,Zakut H

    更新日期:1987-07-01 00:00:00

  • Absence of bilirubin binding competitors during phototherapy for neonatal jaundice.

    abstract::Bilirubin-albumin binding was quantitated (peroxidase method) before, during, and after phototherapy in 21 jaundiced infants. Binding was analyzed at two different serum dilutions (1:1.8 and 1:57) to determine whether binding competitors are present during phototherapy. No significant changes in binding were found at ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(82)90099-8

    authors: Ahlfors CE,Shwer ML,Wennberg RP

    更新日期:1982-04-01 00:00:00