Abstract：
:Candidal chorioamnionitis is an uncommon and apparently rather indolent intrauterine infection in which the fetus is able to marshal some of the immunological forces at its disposal against an easily visualized antigen impinging on lung mucosal surfaces. In a retrospective histological study of one of the largest reported series of these cases, we have encountered one each of 13, 16 and 22 weeks gestation, respectively. Of these, the youngest at 13 weeks showed no inflammatory response or positive cells on immunoperoxidase staining for immunoglobulins and proliferating Candida colonies were evident in the lungs. The 16 and 22 week cases revealed a unique giant cell response in the terminal airways and increasing numbers of cells staining positively for immunoglobulins, predominantly IgM, but with an increased proportion of IgA positive cells in the older case. Preliminary studies with a pan-T-cell antiserum on paraffin-embedded lung tissue from these cases have been encouraging with few positive cells seen in sections from the 13-week or control cases but abundant cells in the lungs of the two older infected cases. Some aspects of the relationship of these uncommonly encountered cases to the ontogeny of human immunity are discussed.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Hood IC,Browning D,de Sa DJ,Whyte RKdoi
10.1016/0378-3782(85)90113-6subject
Has Abstractpub_date
1985-05-01 00:00:00pages
1-10issue
1eissn
0378-3782issn
1872-6232pii
0378-3782(85)90113-6journal_volume
11pub_type
杂志文章abstract：INTRODUCTION:Children born very preterm (VPT) are at increased risk of emotional and behavioral problems later in life. We aimed to determine the prevalence and spectrum of behavioral abnormalities at five years of age in VPT children. METHODS:Multi-center cohort study on 339 early-school aged children born at a gesta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105200
更新日期：2020-12-01 00:00:00
abstract：:The transitional circulation of the preterm infant differs significantly from the term infant. The preterm infant is uniquely at risk of hypotension and low systemic blood flow states due to failure or delay in the normal transitional circulation processes. The maintenance of normal tissue oxygenation requires mainten...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2005.03.006
更新日期：2005-05-01 00:00:00
abstract：:The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01656-n
更新日期：1995-08-18 00:00:00
abstract：:Relationships between maternal factors associated with very slow and very fast fetal growth rate, and the postnatal growth patterns within groups of 238 small-for-dates (SFD) and 241 large-for-dates (LFD) children were examined. Within the SFD group significant differences were found in their weight, height, and to a ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90036-6
更新日期：1982-12-01 00:00:00
abstract：:Nearly 10% of premature infants are born very preterm at 32weeks gestational age or less in the United States. Up to 35% of these very preterm survivors are at risk for cognitive and behavioral deficits. Yet accurate diagnosis of such deficits cannot be made until early childhood. Resting-state fMRI provides noninvasi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.06.002
更新日期：2016-07-01 00:00:00
abstract：BACKGROUND:Zinc and copper are essential for preterm infants, but recommended requirements from different groups vary widely. Recommended zinc intakes have steadily increased over the years. Although this would be expected to impair copper absorption, recommended copper intakes have not risen in parallel. OBJECTIVES:T...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.08.001
更新日期：2013-10-01 00:00:00
abstract：:ROP remains a major cause of childhood blindness worldwide. The smallest, sickest infants develop the most severe forms of zone 1 ROP. Such eyes may not be successfully treated by near confluent laser to the avascular retina (current standard of care). With an understanding of ROP pathogenesis, vascular endothelial gr...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.09.019
更新日期：2012-12-01 00:00:00
abstract：:Twenty appropriate (mean +/- S.D., gestational age (AGA): 29.9 +/- 1.5 weeks) and 15 small (GA: 34.6 +/- 2.4 weeks) for gestational age (SGA) very low birth weight infants fed banked mature human milk were studied until term for anthropometric parameters: midarm (MAC), chest (CC), head (HC) circumferences, triceps (TS...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90051-x
更新日期：1987-09-01 00:00:00
abstract：BACKGROUND:Few studies describe in detail the pregnancy and early development of infants with Prader-Willi syndrome (PWS). However, variations at these early stages may partially account for differences in the later phenotype. A recent paper described an abnormally high number of problems in pregnancy and early infancy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.08.007
更新日期：2008-05-01 00:00:00
abstract：:The modern successes of reproductive medicine are based on the achievements in the fields of artificial fertilization and cryobiology over the last 50years. Cryopreservation of oocytes makes it possible to preserve their reproductive potential after surgical interventions, treatment of cancer, for delayed pregnancy an...
journal_title：Early human development
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.earlhumdev.2018.08.016
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Antenatal depression is associated with adverse social-emotional and behavioural outcomes during childhood but there has been little investigation of the impact on infant neurodevelopment during the first postnatal year. AIMS:The aim of this study was to assess the impact of depression during pregnancy on i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.05.021
更新日期：2019-07-01 00:00:00
abstract：:The early progress of myelination was studied, by means of myelin basic protein (MBP) immunohistochemistry and luxol-fast-blue (LFB) staining, in the spinal cord, spinal nerve roots and brainstem of 66 fetuses and neonates. The degree of myelination was classified from 1 (slight) to 4 (mature). MBP immunoreactivity ex...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)01608-r
更新日期：1995-03-17 00:00:00
abstract：:Low birthweight has been associated with diseases and disorders later in life. It has been suggested that this is caused by the impaired development of abdominal organs, especially in cases of growth retardation. Besides general malnutrition of the fetus, preferential bloodflow to the heart and brain may further depri...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00073-x
更新日期：1998-04-17 00:00:00
abstract：OBJECTIVES:Extremely low birth weight (ELBW; <1kg) adolescents are at risk for special health care needs (SHCN) and poor math achievement compared to normal birth weight (NBW) peers. SHCN are associated with poor academic achievement among NBW children. We hypothesize that SHCN explain the effect of ELBW on math achiev...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.09.019
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND AND AIMS:The interaction between the infant and the caregiver is stated to be very important in the development of a child. When there is inadequacy of interaction, several emotional and developmental problems can emerge. We aimed to investigate the socio-demographic and clinical features of children diagnos...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.09.004
更新日期：2012-06-01 00:00:00
abstract：OBJECTIVE:We evaluated the effect of maternal administration of betamethasone (0.2 mg/kg per day) on mitogen-induced lymphocyte proliferation and interleukin-2 (IL-2) production by maternal, fetal, and neonatal rat splenic lymphocytes. STUDY DESIGN:Betamethasone was injected intramuscularly on days 19 and 20 of gestat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90028-0
更新日期：1994-01-01 00:00:00
abstract：:Surfactant is now available for general clinical use in infants with RDS. While surfactant is effective, it does not prevent lung disease in many preterm infants because of other aspects of lung immaturity. In experimental models, corticosteroids alter the fetal lung by improving compliances, increasing lung volumes, ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(92)90058-o
更新日期：1992-06-01 00:00:00
abstract：:The relationship between the traction forces used in 53 clinically indicated vacuum extractions and the incidence and degree of retinal hemorrhages observed in the neonates within 24 hours after birth was examined. A Vacuum Extractor Recorder (Type SF 30, Knick), was used to measure the traction force necessary for de...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90107-7
更新日期：1988-03-01 00:00:00
abstract：BACKGROUND:Toll-like receptors (TLRs) are part of the highly conserved components of the innate immune system, and have been investigated extensively; however, little is known about TLR function during early postnatal life, a critical period for immune maturation. AIMS:In order to achieve a more complete understanding...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.03.013
更新日期：2013-07-01 00:00:00
abstract：:In 1% of monozygotic twin pregnancies, one fetus is without a heart; blood circulation is maintained by an accompanying "pump" twin. Such an acardiac condition is usually diagnosed on the basis of further malformations visible by ultrasonography. We describe a monoamniotic twin pregnancy with early growth reduction in...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00011-5
更新日期：1998-08-28 00:00:00
abstract：BACKGROUND:Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS:We conducted a case-co...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0378-3782(14)70026-X
更新日期：2014-03-01 00:00:00
abstract：:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to inv...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90027-g
更新日期：1990-12-01 00:00:00
abstract：BACKGROUND:Controversial results have been reported on the effect of type of feeding on the level of fecal calprotectin in infants. OBJECTIVE:To assess fecal calprotectin levels in breast fed or nonbreast fed healthy infants. DESIGN:A study was conducted to compare fecal calprotectin in infants who were exclusively b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.06.005
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:At present, the diagnosis of pulmonary hypoplasia is based on postmortem findings, and there are no clear clinical diagnostic criteria to facilitate its identification and management. AIM:To characterise the respiratory status of pulmonary hypoplasia syndrome (PHS) following preterm rupture of membranes so ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.07.002
更新日期：2004-08-01 00:00:00
abstract：:Index and regression methods of selecting babies whose heads are out of proportion to their body weight are examined and compared. The ratios head circumference3/birthweight and head circumference3/birthweightP (where P is a power found by regression methods) are used, and the regression of head circumference 3 on bir...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(80)90039-0
更新日期：1980-12-01 00:00:00
abstract：BACKGROUND:Septic complications lead to a high mortality rate in very low birthweight infants (VLBWI). Therefore, prognostic markers for the development of sepsis attach importance to start an efficient therapy as early as possible. AIMS:Functional and phenotypical variables of blood monocytes in the cord and peripher...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00245-6
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND AND AIM:Swaddling is a well-known technique in developmental care programs as there is some evidence that swaddling is an appropriate stress-reducing method for preterm infants in the NICU. However, no experimental study has investigated the influence of swaddling in a learning context. This study aimed to a...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105288
更新日期：2021-02-01 00:00:00
abstract：OBJECTIVE:Many preterm children show difficulties in attention at (pre)school age. The development of attention capacities of preterm and term toddlers was compared using a longitudinal and multi-method approach at 12, 18 and 24months. METHOD:Attention was measured for 123 preterm (32-36weeks gestation) and 101 term b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.08.015
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a leading cause of hospitalization for children <1year old and is more severe in premature infants. OBJECTIVE:To assess whether late preterm (LPT) birth is an independent risk factor for RSV hospitalization and more severe RSV disease in children less than 24months old. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.06.009
更新日期：2015-09-01 00:00:00
abstract：:Comparisons of the components of ventilator waveform were made in two groups of preterm infants ventilated for the respiratory distress syndrome. Infants actively expiring against positive pressure inflation were compared to infants not showing this interaction. The actively expiring infants were ventilated with a hig...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(88)80051-3
更新日期：1988-05-01 00:00:00
