Abstract:
:The transitional circulation of the preterm infant differs significantly from the term infant. The preterm infant is uniquely at risk of hypotension and low systemic blood flow states due to failure or delay in the normal transitional circulation processes. The maintenance of normal tissue oxygenation requires maintenance of systemic blood flow and normal blood oxygen levels. Reduction in either of these physiological parameters may result in organ damage, leading to complications such as intraventricular haemorrhage and longer term neurodevelopmental disability. The identification and ongoing monitoring of low systemic blood flow in the preterm infant is more challenging than in older children and some of the assessment techniques used in paediatric and adult intensive care settings do not apply to the neonatal setting. The presence of ductal and atrial shunts makes the measurement of cardiac output problematic in the preterm infant so other newer ways of measuring systemic blood flow need to be considered. The proper treatment of hypotensive and low cardiac output states in the preterm infant requires primarily an understanding of the underlying pathophysiology.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Kluckow Mdoi
10.1016/j.earlhumdev.2005.03.006keywords:
subject
Has Abstractpub_date
2005-05-01 00:00:00pages
429-37issue
5eissn
0378-3782issn
1872-6232pii
S0378-3782(05)00064-2journal_volume
81pub_type
杂志文章,评审abstract::Discrepancies between active and passive muscle power are often seen in pre-term infants over the first year. Generally of a transient nature, they are most obvious in the extensor muscles of the trunk where there is a high active muscle power relative to the passive component. While high active muscle power may not b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(95)01661-l
更新日期:1995-08-30 00:00:00
abstract::The reported energy content of infant formulas will vary, depending upon the method used to calculate or measure the caloric value. Manufacturers' specifications regarding the energy content of milk formulas reflects the 'metabolizable' energy. i.e., the amount of energy which is digested and absorbed by the infant. H...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90124-4
更新日期:1982-07-01 00:00:00
abstract:AIM:To assess whether attrition rate influences outcome in the follow-up of very preterm infants. STUDY DESIGN:In a national follow-up study of infants born alive in 1983 in the Netherlands with a gestational age less than 32 weeks and/or a birth weight less than 1500 g, outcome was assessed separately for adolescents...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.07.006
更新日期:2005-11-01 00:00:00
abstract::White matter injury and abnormal maturation are thought to be major contributors to the neurodevelopmental disabilities observed in children and adolescents who were born preterm. Early detection of abnormal white matter maturation is important in the design of preventive, protective, and rehabilitative strategies for...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2008.09.004
更新日期:2008-12-01 00:00:00
abstract::Breast- and formula-fed infants were compared with regard to behavior patterns, especially crying behavior. A diary concerning seven behaviors was completed by 188 mothers of breast- and formula-fed infants at the well baby clinic. Breast-fed infants were fed more frequently with longer feeding duration. They slept mo...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00071-2
更新日期:2000-05-01 00:00:00
abstract:BACKGROUND:Cases suggestive of non-acidemia related cerebral palsy (CP) are likely misdiagnosed as acidemia related CP because of the presence of nonreasuring fetal heart rate (FHR) patterns. AIMS:Our purpose was to compare intrapartum FHR patterns between the cases of neurological damage and the cases without disabil...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2008.10.007
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:The kidney is one organ which presents distinct morphology depending on GA; the classic references for kidney measurements were established several years ago and it is not certain if they are still accurate. AIM:To evaluate the renal maturity using a computer-assisted morphometry in autopsied fetuses within...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.01.013
更新日期:2006-11-01 00:00:00
abstract::198 infants were followed up from birth until 4 1/2-5 years to observe the development of eczema and asthma and its relation to infant feeding. Findings here refer only to eczema. Comparison between those initially breastfed, regardless of duration, and those fed on cows milk preparations showed little difference in t...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90039-2
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:To compare measurements of the upper arm cross-sectional areas (total arm area, arm muscle area, and arm fat area of healthy neonates) as calculated using anthropometry with the values obtained by ultrasonography. MATERIALS AND METHODS:This study was performed on 60 consecutively born healthy neonates: gesta...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00085-1
更新日期:1999-03-01 00:00:00
abstract::It is convenient to calculate milk energy from the creamatocrit but in order to assess the accuracy with which energy content can be predicted in this way, the creamatocrit, the percentage of carbon, and the calorie value of milk were determined in 11 samples of pooled pasteurised human milk. The calculated milk energ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90121-5
更新日期:1985-05-01 00:00:00
abstract:AIM:The effects of intestinal bifidobacteria on the development of immunity in early life were explored. METHODS:Neonatal SD rats born and housed under strict barrier systems were fed from birth with sufficient antibiotics (bifidobacteria minimisation group) or supplemented daily with 1x10(10) colony-forming units of ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.01.002
更新日期:2010-01-01 00:00:00
abstract::Pancreatic protease deficiency may be an aetiological factor in enteritis necroticans, a disease sharing some features of necrotising enterocolitis (NEC). Using faecal chymotrypsin measurement we have prospectively studied pancreatic exocrine function in infants at risk of NEC. No significant difference was found comp...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(93)90100-9
更新日期:1993-12-15 00:00:00
abstract:OBJECTIVE:To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS:Eighty-one preterm infants b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2017.12.008
更新日期:2018-02-01 00:00:00
abstract:AIMS:1. To determine the survival and morbidity of infants at discharge with a birthweight of less than 1500 g in the geographically defined population of East Anglia. 2. To demonstrate a cost-effective method of regional data collection. 3. To determine whether there were any changes in the demand for neonatal care. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.10.019
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Hospitalized infants requiring cardiopulmonary resuscitation (CPR) represent a high-risk group. Recent data on risk factors for mortality following CPR in this population are lacking. AIMS:We hypothesized that infant demographic characteristics, diagnoses, and levels of cardiopulmonary support at the time o...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.03.015
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Previous studies have reported an increased incidence of thyroid dysfunction in premature/low birth weight infants. The cord blood concentrations of transthyretin (TTR), a thyroid hormone binding protein, have also been found to be decreased in preterm infants. While thyroid hormone concentrations are decrea...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2008.01.001
更新日期:2008-08-01 00:00:00
abstract:INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.08.009
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Maternal smoking during pregnancy is associated with short-term and also long-term harmful effects on offspring. OBJECTIVE:The aim of this study is to evaluate the associations of maternal smoking during pregnancy with offspring bone health at 18years old, and the role of birth weight and contemporaneous he...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.08.024
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:In the general framework of relating birthing events to later mental development, this study addresses the hypothesis that uneventful non-vertex delivery is associated with higher intelligence than uneventful vertex delivery. STUDY DESIGN:In the course of a developmental obstetrical survey, data was gathered...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90065-5
更新日期:1994-09-30 00:00:00
abstract::Doctors are frequently depicted as important protagonists in science fiction, including in the science fiction franchise Star Trek. This paper will profile Drs. Philip Boyce and Mark Piper from the first two Star Trek pilot episodes. These doctors are interdisciplinarians with a variety of skills that permit them to c...
journal_title:Early human development
pub_type: 杂志文章,实务指引
doi:10.1016/j.earlhumdev.2020.104988
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:The osmotic fragility of red blood cells reflects their membrane ability to maintain structural integrity. The osmolality at which the cells lyse is related to their shape, deformability, surface area/volume ratio and intrinsic membrane properties. In cord blood, there may be differences between premature an...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(03)00009-4
更新日期:2003-05-01 00:00:00
abstract::To determine the assessments before discharge from the intensive care unit, that will predict outcome most accurately, a prospective longitudinal study in a cohort of 79 high risk VLBW children was conducted from birth to 3.6 years of age. Birthweight, gestational age, obstetrical and neonatal optimality, neonatal neu...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90040-n
更新日期:1992-12-01 00:00:00
abstract::The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(86)90186-6
更新日期:1986-12-01 00:00:00
abstract:UNLABELLED:The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1.5 mg/kg, 6 hourly] or placebo was given first over 7 days in a double blind randomized crossover study of 21 preterm infants with feed intolerance. Median [r...
journal_title:Early human development
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-3782(01)00191-8
更新日期:2001-12-01 00:00:00
abstract::There is convincing evidence that breast-feeding is protective against gastro-enteritis and diarrhoea, but for other infections the situation is less clear cut. There is evidence that breast-fed infants are at increased risk of one infection (infant botulism). They are probably not significantly protected from upper r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00056-x
更新日期:1997-10-29 00:00:00
abstract:BACKGROUND:The long-term effect of early intervention in infants at risk for developmental disorders is unclear. The VIP project (n=46, originally) evaluated by means of a randomised controlled trial the effect of the family centred early intervention programme COPCA (Coping with and Caring for infants with special nee...
journal_title:Early human development
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.earlhumdev.2017.02.002
更新日期:2017-01-01 00:00:00
abstract::The mediating effect of maternal self-efficacy in the association between locus of control and anxiety, among mothers of hospitalized babies in the Neonatal Intensive Care Unit (NICU) was examined. Findings confirmed partial mediation effect suggesting that professionals can contribute to the reduction of levels of an...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105284
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.10.003
更新日期:2016-12-01 00:00:00
abstract::The objectives of this study were (1) to detect vasoactive intestinal polypeptide in fetal blood obtained by cordocentesis (2) to examine possible changes in growth retarded fetuses and to establish relationships between its levels and fetal blood acid-base status as well as fetal haemodynamics as assessed by Doppler ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)01610-2
更新日期:1995-03-17 00:00:00
abstract:BACKGROUND:At present, the diagnosis of pulmonary hypoplasia is based on postmortem findings, and there are no clear clinical diagnostic criteria to facilitate its identification and management. AIM:To characterise the respiratory status of pulmonary hypoplasia syndrome (PHS) following preterm rupture of membranes so ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.07.002
更新日期:2004-08-01 00:00:00