Abstract：
:To determine the assessments before discharge from the intensive care unit, that will predict outcome most accurately, a prospective longitudinal study in a cohort of 79 high risk VLBW children was conducted from birth to 3.6 years of age. Birthweight, gestational age, obstetrical and neonatal optimality, neonatal neurological examinations and neonatal cerebral ultrasound were studied in relation to outcome. The best predictor for outcome was a simple cerebral ultrasound classification according to the presence or absence of ventriculomegaly and intraparenchymal damage of any cause. Infants with normal neonatal cerebral scans or abnormal scans without ventriculomegaly almost invariably had a normal neurological outcome. In infants with cerebral lesions with ventriculomegaly the incidence of normal neurological outcome decreased to less than 50%. Intraparenchymal damage was associated with cerebral palsy as well as other (mental and sensori) handicaps in over 85% of the cases. Neonatal neurological examinations at preterm age had additional value in predicting neurological outcome especially in the group with ventriculomegaly. Neither birthweight, nor gestational age, obstetrical or neonatal optimality were independent variables in the prediction of outcome in high risk VLBW children at 3.6 years of age.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Weisglas-Kuperus N,Baerts W,Fetter WP,Sauer PJdoi
10.1016/0378-3782(92)90040-nkeywords:
subject
Has Abstractpub_date
1992-12-01 00:00:00pages
131-48issue
2eissn
0378-3782issn
1872-6232pii
0378-3782(92)90040-Njournal_volume
31pub_type
杂志文章abstract：OBJECTIVE:To compare paired antepartum fetal/maternal COHb ratios in whole blood from control and alloimmunized pregnancies and to examine the relationships between fetal and maternal COHb. METHODS:COHb levels were measured in paired fetal and maternal blood samples obtained at cordocentesis in 47 control and 16 Rh-al...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00079-7
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Several studies report increased minor neurodevelopment dysfunctions in children born very low birth weight (VLBW). Usefulness of preventive early intervention programs to improve neurodevelopment outcome of VLBW infants is still under investigation. AIMS:To evaluate the effects of an early post-discharge d...
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2006.01.011
更新日期：2006-10-01 00:00:00
abstract：:Atrial natriuretic factor (ANF) has been well known as a potent natriuretic peptide. The purpose of this study was to clarify the physiological role of ANF in neonates. We designed two types of study to investigate the role of ANF in neonates. (i) The role of ANF in neonatal fluid homeostasis; (ii) ANF and spontaneous...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90132-z
更新日期：1992-06-01 00:00:00
abstract：OBJECTIVE:We evaluated the effect of maternal administration of betamethasone (0.2 mg/kg per day) on mitogen-induced lymphocyte proliferation and interleukin-2 (IL-2) production by maternal, fetal, and neonatal rat splenic lymphocytes. STUDY DESIGN:Betamethasone was injected intramuscularly on days 19 and 20 of gestat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90028-0
更新日期：1994-01-01 00:00:00
abstract：:Doctors are pivotal characters in Star Trek. This paper will review Dr. Julian Bashir, a unique medic who is genetically engineered to superhuman capacities while deliberately designed to have human failings, which he successfully overcomes. His genetic enhancements allow him to excel in whatever he does and although ...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2020.104992
更新日期：2020-05-01 00:00:00
abstract：:The calculation of descriptive statistics after data collection provides researchers with an overview of the shape and nature of their datasets, along with basic descriptors, and may help identify true or incorrect outlier values. This exercise should always precede inferential statistics, when possible. This paper pr...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.02.015
更新日期：2018-03-01 00:00:00
abstract：:Fifty-one British newborn infants and 51 Japanese newborn infants were compared using Prechtl's neonatal neurological examination and Brazelton's neonatal behavioural assessment scale on the 5th day after birth. Statistically significant differences were found between the two groups. British infants were more responsi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90172-d
更新日期：1992-03-01 00:00:00
abstract：BACKGROUND AND AIMS:The interaction between the infant and the caregiver is stated to be very important in the development of a child. When there is inadequacy of interaction, several emotional and developmental problems can emerge. We aimed to investigate the socio-demographic and clinical features of children diagnos...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.09.004
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Previous studies have reported an increased incidence of thyroid dysfunction in premature/low birth weight infants. The cord blood concentrations of transthyretin (TTR), a thyroid hormone binding protein, have also been found to be decreased in preterm infants. While thyroid hormone concentrations are decrea...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.01.001
更新日期：2008-08-01 00:00:00
abstract：:Relationships between maternal factors associated with very slow and very fast fetal growth rate, and the postnatal growth patterns within groups of 238 small-for-dates (SFD) and 241 large-for-dates (LFD) children were examined. Within the SFD group significant differences were found in their weight, height, and to a ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90036-6
更新日期：1982-12-01 00:00:00
abstract：BACKGROUND:Using pure oxygen (PO) in neonatal resuscitation increases oxidative stress and mortality in full-term hypoxic infants. International neonatal resuscitation guidelines recommend air or blended oxygen for resuscitation regardless of gestational age but this requires education and equipment that may not be glo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.01.005
更新日期：2012-08-01 00:00:00
abstract：:Previous studies which have quantitated tissue mRNA transcripts have suggested that IGF II is expressed in substantially greater amounts than IGF I during human fetal development. However, this has not been tested directly by recovery and quantitation of IGF peptides from fetal tissues. Tissues from human fetuses were...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90110-5
更新日期：1990-01-01 00:00:00
abstract：BACKGROUND:Preterm newborns have low vitamin A reserves at birth, which increases their risk of morbidity and mortality. In the absence of supplementation, breast milk is the only source of this nutrient for exclusively breastfed infants. AIMS:To assess retinol concentration in preterm milk and the relationship betwee...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.01.006
更新日期：2017-01-01 00:00:00
abstract：:As major sport events have been cancelled and postponed in response to COVID-19, the necessity to protect and provide a holistic approach to the professional athlete has never been greater. To do so one must understand the negative consequences for athletes in relation to the cancellation and postponement of such even...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105254
更新日期：2020-11-12 00:00:00
abstract：:In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90140-e
更新日期：1990-11-01 00:00:00
abstract：:Increasing public awareness of the prone sleeping position, maternal smoking and overheating as potentially avoidable risk factors for the sudden infant death syndrome (SIDS) has been accompanied by a dramatic reduction in mortality. The results of two population based studies of SIDS in Avon are compared; the first o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90208-9
更新日期：1994-09-15 00:00:00
abstract：BACKGROUND:Bright constant light levels in the NICU may have negative effects on the growth and development of preterm infants OBJECTIVE:The aim of this study is to evaluate the benefits of an alternating light/dark cycle in the NICU on weight gain and early discharge from the therapy in premature infants. PATIENTS A...
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2014.04.015
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:Animal experiments have convincingly demonstrated that prenatal maternal stress affects pregnancy outcome and results in early programming of brain functions with permanent changes in neuroendocrine regulation and behaviour in offspring. AIM:To evaluate the existing evidence of comparable effects of prenata...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(02)00075-0
更新日期：2002-12-01 00:00:00
abstract：:Lipids have physical, chemical, and physiological properties that make them important factors in human nutrition. They form a group of compounds of varied chemical nature that have the common property of being soluble in organic solvents but insoluble in water. This basic property affects their digestion, absorption, ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(01)00211-0
更新日期：2001-11-01 00:00:00
abstract：BACKGROUND:Even though the biological norm in humans is frequent on demand breastfeeding, sparse feeding intervals have become the cultural norm in most Western countries due to a history of on schedule breastfeeding. This discrepancy between the biological basis and the culturally driven practice continues to interfer...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105242
更新日期：2020-12-01 00:00:00
abstract：:We have investigated infant-caregiver interactions in an isolated African subsistence farming community where women perform arduous agricultural tasks in addition to their normal domestic duties which include child care. 49 babies aged 3-18 months were studied on one or two occasions. Detailed observations were made o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90139-2
更新日期：1985-10-01 00:00:00
abstract：:The early progress of myelination was studied, by means of myelin basic protein (MBP) immunohistochemistry and luxol-fast-blue (LFB) staining, in the spinal cord, spinal nerve roots and brainstem of 66 fetuses and neonates. The degree of myelination was classified from 1 (slight) to 4 (mature). MBP immunoreactivity ex...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)01608-r
更新日期：1995-03-17 00:00:00
abstract：BACKGROUND:Preterm infants have immature skin, which contributes to skin problems. Very little is known about postnatal changes in the skin, despite the clinical importance of this issue. AIM:To assess temporal changes in skin water content in preterm infants. STUDY DESIGN:A prospective observational study. SUBJECTS...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.05.009
更新日期：2015-09-01 00:00:00
abstract：:We have shown for the first time that the microsomal glucose-6-phosphatase enzyme protein is present in human embryonic and fetal red blood cells and the ontogeny of its expression has been determined. In the earliest embryos, red cells are predominantly of the primitive megaloblastic type. Circulating red cells in th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01626-e
更新日期：1995-06-21 00:00:00
abstract：BACKGROUND:It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. AIMS:To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. STUDY DESIGN:Retrospective cohort stu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.03.006
更新日期：2015-05-01 00:00:00
abstract：:Surfactant is now available for general clinical use in infants with RDS. While surfactant is effective, it does not prevent lung disease in many preterm infants because of other aspects of lung immaturity. In experimental models, corticosteroids alter the fetal lung by improving compliances, increasing lung volumes, ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(92)90058-o
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:Zinc and copper are essential for preterm infants, but recommended requirements from different groups vary widely. Recommended zinc intakes have steadily increased over the years. Although this would be expected to impair copper absorption, recommended copper intakes have not risen in parallel. OBJECTIVES:T...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.08.001
更新日期：2013-10-01 00:00:00
abstract：:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to inv...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90027-g
更新日期：1990-12-01 00:00:00
abstract：:Maturation of spontaneous fetal body and breathing movements of 24- to 33-week-old fetuses in 168 pregnancies threatening to deliver prematurely were examined on the basis of newborn outcome (premature compromised, premature healthy, term healthy). Maturation of fetuses in 60 low-risk pregnancies delivering as healthy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00007-9
更新日期：1999-05-01 00:00:00
abstract：:In the scholarly environment, research findings are disseminated as journal papers which support/dispute extant knowledge or add further to what is already known. The entire manuscript needs to be cited (in-text) and referenced (at the end of article), in order for readers to ascertain the validity of the research cla...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.09.012
更新日期：2019-01-01 00:00:00
