Postnatal changes in skin water content in preterm infants.

Abstract:

BACKGROUND:Preterm infants have immature skin, which contributes to skin problems. Very little is known about postnatal changes in the skin, despite the clinical importance of this issue. AIM:To assess temporal changes in skin water content in preterm infants. STUDY DESIGN:A prospective observational study. SUBJECTS:Infants admitted to the neonatal intensive care unit were included in this study. OUTCOME MEASURES:Skin water content was measured at five different skin regions using dielectric methods at a depth of 1.5mm. Skin water content was measured on postnatal day 1 in 101 infants, and the correlation between skin water content and gestational week was analyzed. Measurements were also made on postnatal days 2, 3, and 7, and every 7days thereafter until the corrected age of 37weeks in 87 of the 101 infants. Temporal changes were statistically analyzed after dividing participants into seven groups by gestational age. RESULTS:On postnatal day 1, skin water content correlated inversely with gestational age at all skin regions. Skin water content decreased significantly over time, converging to the level of term infants by the corrected age of 32-35weeks. CONCLUSIONS:Skin water content at a depth of 1.5mm was related to corrected age and reached the level of term infants by the corrected age of approximately 32-35weeks.

journal_name

Early Hum Dev

journal_title

Early human development

authors

Ishiguro A,Fujinuma S,Motojima Y,Oka S,Komaki T,Saito A,Kawasaki H,Araki S,Kanai M,Sobajima H,Tamura M

doi

10.1016/j.earlhumdev.2015.05.009

subject

Has Abstract

pub_date

2015-09-01 00:00:00

pages

505-9

issue

9

eissn

0378-3782

issn

1872-6232

pii

S0378-3782(15)00122-X

journal_volume

91

pub_type

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