Abstract:
:Maturation of spontaneous fetal body and breathing movements of 24- to 33-week-old fetuses in 168 pregnancies threatening to deliver prematurely were examined on the basis of newborn outcome (premature compromised, premature healthy, term healthy). Maturation of fetuses in 60 low-risk pregnancies delivering as healthy full-term infants served as a normative comparison group. Each fetus was observed for 30 min; the amount of body and breathing movements were noted and an estimation of amniotic fluid volume was made. The pattern of behavioural maturation was similar for all outcome groups; with advancing gestation there was a decrease in body movements and an increase in breathing movements. Both reduced activity levels and advanced behaviours were observed in the high-risk outcome groups. The high-risk fetuses had reduced levels of body movements which increased with better outcome and, an earlier onset of increased amounts of breathing, occurring at 30 weeks in contrast to 33 weeks for the comparison group. In the presence of ruptured membranes, those high-risk fetuses who were born prematurely had less breathing compared to those who delivered at term. Similar maturation patterns among high- and low-risk outcome groups suggests normal/typical functional development in the high-risk fetal groups. The observed differential behaviours were associated with prematurity and most likely associated with events leading to premature labour.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Kisilevsky BS,Hains SM,Low JAdoi
10.1016/s0378-3782(99)00007-9keywords:
subject
Has Abstractpub_date
1999-05-01 00:00:00pages
25-38issue
1eissn
0378-3782issn
1872-6232pii
S0378-3782(99)00007-9journal_volume
55pub_type
杂志文章abstract:OBJECTIVE:To assess whether patterns of growth trajectory during infancy are associated with intelligence quotient (IQ) scores at 4 years of age in children born small-for-gestational age (SGA). METHODS:Children in the Collaborative Perinatal Project born SGA were eligible for analysis. The primary outcome was the Sta...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.06.002
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Previous studies using ultrasound technology showed that fetal heart rate (HR) may be responsive to maternal aerobic exercise. Although it is recognized that cardiac autonomic control may be influenced by the intrauterine environment, little is known about how maternal exercise affects fetal heart developmen...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.03.002
更新日期:2010-04-01 00:00:00
abstract::The anatomical findings of sirenomelia in a 12-weeks aborted embryo are reported. The occurrence of sirenomelia in material from spontaneous abortions is discussed. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(87)90080-6
更新日期:1987-07-01 00:00:00
abstract::Mother's own milk is widely recognized as the optimal feeding for term infants, but also provides health benefits that are of vital importance for sick and preterm infants in neonatal intensive care units (NICUs), even though the growth and neurodevelopmental needs of very premature infants are best met by appropriate...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2013.07.008
更新日期:2013-10-01 00:00:00
abstract::The aim of the study was to evaluate potential changes of cerebral blood volume (CBV) related to arousals in preterm infants. As arousals are known to change different physiological parameters, it was postulated that this could also hold true for CBV. Polygraphic recordings were performed in 38 preterm infants (18 fem...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.05.019
更新日期:2007-04-01 00:00:00
abstract:PURPOSE:This pilot study compared the physiological and behavioural changes in premature infants undergoing three different methods of screening for retinopathy of prematurity (ROP). STUDY DESIGN:Prospective randomized cross-over pilot study. SUBJECTS AND METHODS:Fifteen premature infants requiring screening for ROP ...
journal_title:Early human development
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/j.earlhumdev.2004.09.005
更新日期:2005-04-01 00:00:00
abstract:INTRODUCTION:Reduced left ventricular (LV) diastolic function can exert significant load to the right ventricle (RV) that can affect RV-pulmonary vasculature (PV) coupling. RV-PV can be assessed with the RV length-force relationship (tricuspid annular plane systolic excursion [TAPSE] to pulmonary artery acceleration ti...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.11.006
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Early iron supplementation in women with sufficient reserves could provoke iron excess resulting in haemoconcentration and low infant birth weight (IBW). AIM:To clarify the influence of early iron supplementation on maternal iron status and the IBW, taking into account pre-pregnancy iron deposits. STUDY DE...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.06.003
更新日期:2011-12-01 00:00:00
abstract:INTRODUCTION:Little is known about sex differences in human fetal heart and behaviour. PATIENTS AND METHODS:One hundred twenty-three nulliparous healthy women carrying a male (n=56) or female (n=67) fetus participated in this study. All pregnancies remained uncomplicated and delivery was uneventful. Ultrasound observa...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(03)00047-1
更新日期:2003-08-01 00:00:00
abstract::Lenticulostriate vasculopathy (LSV) is a diagnosis dependent on neonatal cranial ultrasound (US). The diagnosis of LSV requires the presence of linear or branching echogenicities in the area of the basal ganglia and/or thalamus on gray scale cranial US. Although the diagnosis of LSV is dependent on cranial US, there a...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2015.04.003
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND AND AIM:Swaddling is a well-known technique in developmental care programs as there is some evidence that swaddling is an appropriate stress-reducing method for preterm infants in the NICU. However, no experimental study has investigated the influence of swaddling in a learning context. This study aimed to a...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105288
更新日期:2021-02-01 00:00:00
abstract:BACKGROUND:Hypoxic-ischemic brain injury (HIBI) is a common cause of neonatal mortality and morbidity. The use of levetiracetam (LEV), as a potential neuroprotective in brain ischemia, receives an increasingly high attention, and it could have a crucial role in the regulation of epileptogenesis and neuroprotection. Pot...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.12.002
更新日期:2013-05-01 00:00:00
abstract::Whenever possible, oral feeding is the preferred method in neonatal feeding. However, many premature infants are unable to suck and swallow effectively; in these cases alternative methods of nutrient delivery must be used. We briefly review the different feeding methods used in neonatal units, with particular attentio...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/S0378-3782(12)70011-7
更新日期:2012-05-01 00:00:00
abstract::The reported energy content of infant formulas will vary, depending upon the method used to calculate or measure the caloric value. Manufacturers' specifications regarding the energy content of milk formulas reflects the 'metabolizable' energy. i.e., the amount of energy which is digested and absorbed by the infant. H...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90124-4
更新日期:1982-07-01 00:00:00
abstract::CMV is the most common congenital infection in newborns worldwide. Congenital CMV causes sensorineural hearing loss in a significant proportion of infected newborns, while the majority of newborns are asymptomatic. In the last three years there have been significant advances in the diagnosis and treatment of congenita...
journal_title:Early human development
pub_type: 杂志文章,实务指引
doi:10.1016/j.earlhumdev.2011.08.021
更新日期:2011-11-01 00:00:00
abstract::This study examined the risk factors for respiratory distress syndrome (RDS) in preterm infants from pregnancies complicated by placenta previa. Forty preterm infants born to mothers with placenta previa between January 1989 and December 1995 in a medical center were enrolled. Each of these patients was matched in ges...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00121-3
更新日期:2001-01-01 00:00:00
abstract::Lipids have physical, chemical, and physiological properties that make them important factors in human nutrition. They form a group of compounds of varied chemical nature that have the common property of being soluble in organic solvents but insoluble in water. This basic property affects their digestion, absorption, ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(01)00211-0
更新日期:2001-11-01 00:00:00
abstract:BACKGROUND:Parent perception of child vulnerability (PPCV) and parent overprotection (POP) are believed to have serious implications for age appropriate cognitive and psychosocial development in very low birth weight preterm children. AIM:With recent concerns about suboptimal developmental outcomes in late-preterm chi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.07.005
更新日期:2010-09-01 00:00:00
abstract::Whether preeclampsia affects the fetal hematologic system still remains a controversial issue. The purpose of this series was to examine the hypothesis that preeclampsia may or may not cause adverse effects on fetal hemogram, including erythrocytes, leukocytes, and platelets. In addition, no one, to date, has reported...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90150-3
更新日期:1994-05-01 00:00:00
abstract::198 infants were followed up from birth until 4 1/2-5 years to observe the development of eczema and asthma and its relation to infant feeding. Findings here refer only to eczema. Comparison between those initially breastfed, regardless of duration, and those fed on cows milk preparations showed little difference in t...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90039-2
更新日期:1984-04-01 00:00:00
abstract::Eleven healthy, full-term babies were studied on the second day (d2) after birth and again 4 weeks (w4) later. The babies lived in natural lighting conditions and were fed every 4 h. Blood pressure, heart rate, skin (abdomen) and rectal temperatures were measured at 10-min intervals for 24 h. Behavioural states (deep ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90039-6
更新日期:1994-02-01 00:00:00
abstract::Measurement of methionine levels in dried blood spots has been one of the items of neonatal screening in Taiwan for more than 20 years. In 1,701,591 newborns, 17 cases of hypermethioninemia were detected, but among them only one had homocystinuria. More than half of the 16 cases of isolated hypermethioninemia had muta...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.11.005
更新日期:2005-06-01 00:00:00
abstract:BACKGROUND:Practically all reference curves for Doppler blood flow variables in pregnancy end at 40 weeks. OBJECTIVE:To study fetal and uteroplacental circulatory changes in pregnancies proceeding beyond 43 weeks. STUDY DESIGN:Longitudinal comparisons from 42 to 43 weeks and comparisons with controls at term. MATERI...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(96)01736-7
更新日期:1996-09-20 00:00:00
abstract:BACKGROUND:Term equivalent age (TEA) brain MRI identifies preterm infants at risk for adverse neurodevelopmental outcomes. But some infants may experience neurodevelopmental impairments even in the absence of neuroimaging abnormalities. OBJECTIVE:Evaluate the association of TEA amplitude-integrated EEG (aEEG) measures...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.02.010
更新日期:2018-04-01 00:00:00
abstract:AIMS:1. To determine the survival and morbidity of infants at discharge with a birthweight of less than 1500 g in the geographically defined population of East Anglia. 2. To demonstrate a cost-effective method of regional data collection. 3. To determine whether there were any changes in the demand for neonatal care. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.10.019
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:Using pure oxygen (PO) in neonatal resuscitation increases oxidative stress and mortality in full-term hypoxic infants. International neonatal resuscitation guidelines recommend air or blended oxygen for resuscitation regardless of gestational age but this requires education and equipment that may not be glo...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.01.005
更新日期:2012-08-01 00:00:00
abstract::805 normal-for-age human embryos and fetuses were used to study early prenatal fat development. The investigation included observations on stages of fat morphogenesis at the light microscopic level and computerized image analyses of fat lobule size and number. The buccal fat pad was selected as a model system for the ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(83)90028-2
更新日期:1983-03-01 00:00:00
abstract::Newborn infants, especially preterm infants, have an immature immune system, which is not capable to actively protect against vaccine-preventable infections. Therefore, the newborn is dependent on transplacental transport of Immunoglobulin G (IgG), an active, FcRn receptor mediated process. Fetal IgG rises from approx...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2010.11.003
更新日期:2011-02-01 00:00:00
abstract::Management of neonatal hydronephrosis is a clinical challenge. The natural history of hydronephrosis has shown that most resolve spontaneously; however, there are a significant number that do not. Although hydronephrosis does not always mean obstruction, it becomes the clinician's role to determine when obstruction wi...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2005.11.004
更新日期:2006-01-01 00:00:00
abstract::The aims of the study were (1) to replicate previous quantitative studies of motor activity in low-risk and high-risk preterm infants and (2) to apply a new method of systematic analysis of the qualitative characteristics of general movements in these two groups of infants. Sequential one-hour videorecordings of the u...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(90)90013-9
更新日期:1990-09-01 00:00:00