Abstract：
BACKGROUND:Practically all reference curves for Doppler blood flow variables in pregnancy end at 40 weeks. OBJECTIVE:To study fetal and uteroplacental circulatory changes in pregnancies proceeding beyond 43 weeks. STUDY DESIGN:Longitudinal comparisons from 42 to 43 weeks and comparisons with controls at term. MATERIAL:Thirty-four women delivered after 43 completed weeks (301 days) and a control group of 32 women delivered at 271 days of gestation. METHODS:From 42 weeks (294 days), serial Doppler blood flow measurements were performed in the fetal descending aorta, umbilical vessels, and maternal uterine artery. STATISTICAL METHODS:Student's unpaired t-test, Mann-Whitney U-test, and Fisher's exact test for comparison of groups; Student's paired t-test and Wilcoxon's signed-rank matched-pairs test for longitudinal data; simple linear regression analysis for comparison of variables. A two-tailed P-value of < 0.05 was considered statistically significant. RESULTS:From 42 to 43 weeks, the mean flow velocity decreased significantly in the fetal aorta and increased significantly in the umbilical vein. Compared to controls, the velocity and volume flow in the aorta and the umbilical artery flow resistance were significantly lower at 43 weeks. No significant change in uterine artery flow resistance was found. CONCLUSIONS:The changes in Doppler blood flow variables were all in accordance with physiological circulatory alterations enhancing continued fetal growth until the late post-term period. There were no signs of any general circulatory deterioration. Doppler velocimetry reference values at term may not be appropriate for evaluation of very advanced gestations.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Olofsson P,Saldeen P,Marsál Kdoi
10.1016/0378-3782(96)01736-7subject
Has Abstractpub_date
1996-09-20 00:00:00pages
1-13issue
1-2eissn
0378-3782issn
1872-6232pii
0378-3782(96)01736-7journal_volume
46pub_type
杂志文章abstract：:Urinary epidermal growth factor (EGF) excretion was studied serially in 36 newborn infants, from 26 to 40 weeks gestation, from birth to three months of age. All infants excreted EGF from birth. Excretion was significantly higher in term infants than in preterm infants at birth; in term infants excretion rose steadily...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90190-8
更新日期：1986-12-01 00:00:00
abstract：BACKGROUND:Movement by an infant during the first year of life might influence its activity level and thereby influence growth in early childhood. AIM:To examine whether the time that an infant is able to move unrestrictedly and time spent in baby seats are related to weight and waist circumference at age 9 months and...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.04.002
更新日期：2013-07-01 00:00:00
abstract：:Abnormal hypertonia of the neck extensor muscles in newborns may be appreciated by observing spontaneous posture, evaluating resistance to repeated passive flexion of the head, and eliciting the head straightening reflexes. This sign correlates well with other signs of insult to the central nervous system. Of 1743 new...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90019-6
更新日期：1977-10-01 00:00:00
abstract：OBJECTIVE:To compare paired antepartum fetal/maternal COHb ratios in whole blood from control and alloimmunized pregnancies and to examine the relationships between fetal and maternal COHb. METHODS:COHb levels were measured in paired fetal and maternal blood samples obtained at cordocentesis in 47 control and 16 Rh-al...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00079-7
更新日期：2000-06-01 00:00:00
abstract：OBJECTIVES:To investigate the effects of single and repeated courses of antenatal corticosteroids on brain growth in very preterm babies. DESIGN:Retrospective study of 110 very preterm babies delivered at a single University Teaching Hospital between 1992 and 1999 who had a full necropsy including detailed examination...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00144-x
更新日期：2001-07-01 00:00:00
abstract：BACKGROUND:Preterm birth is a known risk factor for infant development but it is less clear whether fetal growth restriction (FGR) and early term birth between 37 and 39 weeks gestation are associated with risks for infant development. AIMS:This study investigated risk factors for adverse developmental outcomes at 12 ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.104951
更新日期：2020-03-01 00:00:00
abstract：OBJECTIVE:To investigate whether maternal obesity poses a risk for long-term cardiovascular morbidity in the offspring. STUDY DESIGN:Data were analyzed from a non-selective population of all infants born between the years 1991-2014 at the tertiary Soroka University Medical Center (SUMC), the sole hospital in the south...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105221
更新日期：2020-12-01 00:00:00
abstract：:Insulin-like growth factor-1 (IGF-1) and insulin-like growth factor binding protein-1 (IGFBP-1) were measured in amniotic fluid, extraembryonic coelomic fluid and maternal serum from 23 women with apparently normal first trimester pregnancies prior to termination. The levels of IGF-1 and IGFBP-1 were significantly hig...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90105-p
更新日期：1992-02-01 00:00:00
abstract：:The diagnosis, acute management and follow-up of neonates with haemolytic disease of the newborn (HDN) still represents a significant area of activity for maternity/neonatal services. ABO incompatability is now the single largest cause of HDN in the western world. However, with increasing knowledge at the molecular le...
journal_title：Early human development
pub_type： 杂志文章,实务指引,评审
doi：10.1016/j.earlhumdev.2008.06.005
更新日期：2008-08-01 00:00:00
abstract：:Maternal milk four days post partum contained immunoreactive calcitonin in concentrations which were 22-89 times higher than those noted in concomitantly sampled maternal sera. Neurotensin-like immunoreactivity was barely detectable in milk. It is suggested that calcitonin may be a prerequisite for the concentration o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90060-3
更新日期：1982-01-01 00:00:00
abstract：:Breast- and formula-fed infants were compared with regard to behavior patterns, especially crying behavior. A diary concerning seven behaviors was completed by 188 mothers of breast- and formula-fed infants at the well baby clinic. Breast-fed infants were fed more frequently with longer feeding duration. They slept mo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00071-2
更新日期：2000-05-01 00:00:00
abstract：OBJECTIVE:To evaluate the newborn transient evoked otoacoustic emission (TEOAE) hearing screening tests of infants later diagnosed with the sudden infant death syndrome (SIDS). STUDY DESIGN:In a case-controlled study, the newborn TEOAE hearing screens of 31 infants who subsequently died of SIDS were retrospectively co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.06.001
更新日期：2008-04-01 00:00:00
abstract：:As major sport events have been cancelled and postponed in response to COVID-19, the necessity to protect and provide a holistic approach to the professional athlete has never been greater. To do so one must understand the negative consequences for athletes in relation to the cancellation and postponement of such even...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105254
更新日期：2020-11-12 00:00:00
abstract：BACKGROUND:Human milk contains a range of host defence proteins that appear to contribute to health and wellbeing, but their variability in abundance among individuals has not been very well characterised. Milk from mothers of premature infants has altered composition, but the effect of gestation length on the host-def...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：:gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease wi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90007-x
更新日期：1982-10-01 00:00:00
abstract：:A fetus with signs of hydrops is at high risk of intrauterine death. The pathophysiology of hydrops fetalis is still unclear. We found decreased concentrations of cyclic guanosine monophosphate in fetal plasma of alloimmunized pregnancies complicated by hydrops fetalis, which might suggest reduced nitric oxide product...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00063-8
更新日期：2000-03-01 00:00:00
abstract：INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.08.009
更新日期：2013-02-01 00:00:00
abstract：BACKGROUND:Prior studies have shown that children with congenital hearing loss have increased rates of behavior disorders. Child hearing loss has also been reported to be associated with increased maternal stress. Little is known about the behavior or the predictors of behavioral outcomes of children with hearing loss ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.06.006
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Previous studies have reported an increased incidence of thyroid dysfunction in premature/low birth weight infants. The cord blood concentrations of transthyretin (TTR), a thyroid hormone binding protein, have also been found to be decreased in preterm infants. While thyroid hormone concentrations are decrea...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.01.001
更新日期：2008-08-01 00:00:00
abstract：:This study examined the oral sensitivity and feeding skills of low-risk pre-term infants at 11-17 months corrected age. Twenty pre-term infants (PT) born between 32 and 37 weeks at birth without any medical comorbidities were assessed. All of this PT group received supplemental nasogastric (NG) tube feeds during their...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.10.001
更新日期：2004-01-01 00:00:00
abstract：:Lung surfactant was obtained by postmortem lavage from: (A) premature babies: 34 dying acutely within 2 days of birth from Hyaline Membrane Disease (HMD), 20 dying several days after birth with HMD and its consequences, 8 dying from causes other than HMD; (B) mature babies: 24 dying stillborn, 15 dying soon after birt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90094-1
更新日期：1988-03-01 00:00:00
abstract：:A management programme for the control and treatment of Rh0 (D) immunized during pregnancy is presented. A total of 34,650 births were registered during a 4.5 year period and included 63 D positive newborns to D-immunized mothers. The outcome of all infants has been evaluated according to the severity of the haemolyti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90096-x
更新日期：1987-01-01 00:00:00
abstract：:Doctors are pivotal characters in Star Trek. This paper will review Dr. Julian Bashir, a unique medic who is genetically engineered to superhuman capacities while deliberately designed to have human failings, which he successfully overcomes. His genetic enhancements allow him to excel in whatever he does and although ...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2020.104992
更新日期：2020-05-01 00:00:00
abstract：INTRODUCTION:The male-to-female ratio of live births is expressed as the ratio of male births divided by total births (M/F). Males are produced approximately 3% in excess. A large number of factors have been found to influence M/F. Stress and privation reduces M/F. Gender preference (which almost invariably favours mal...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.10.013
更新日期：2015-12-01 00:00:00
abstract：OBJECTIVES:Extremely low birth weight (ELBW; <1kg) adolescents are at risk for special health care needs (SHCN) and poor math achievement compared to normal birth weight (NBW) peers. SHCN are associated with poor academic achievement among NBW children. We hypothesize that SHCN explain the effect of ELBW on math achiev...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.09.019
更新日期：2017-12-01 00:00:00
abstract：:The presence of dilated bowel loops antenatally suggests fetal bowel obstruction. Neonatal intestinal obstruction can have different variations in presentation depending on the level and extent of obstruction. Some of these conditions can be diagnosed antenatally. Antenatal detection of surgically correctable anomalie...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2006.02.005
更新日期：2006-05-01 00:00:00
abstract：BACKGROUND:Patent ductus arteriosus (PDA) is a frequent problem in preterm infants, and its incidence is inversely correlated with gestational age. The efficacy of medical treatment decreases with decreasing gestational age (GA), and failure rates as well as ductus ligation rates of 40% have been reported in <28 week G...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.06.012
更新日期：2010-08-01 00:00:00
abstract：:Dexamethasone (DEX), a synthetic glucocorticoid, has been widely used to prevent the development of a variety of poor health conditions in premature infants including chronic lung disease, inflammation, circulatory failure, and shock. Although there are some reports of neurologic complications related to DEX exposure,...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.10.007
更新日期：2013-05-01 00:00:00
abstract：:The evolution of ultrasound findings in 59 infants with transient periventricular densities is described and the neurodevelopmental outcome of 53 of these infants was compared with 92 of 107 infants with normal ultrasound scans, born during the same 24-month period. Four of the 53 infants with transient periventricula...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90103-x
更新日期：1988-03-01 00:00:00
abstract：BACKGROUND:Preterm children have problems with mathematics but knowledge about the predictors of specific mathematic abilities in preterm populations is scarce. AIMS:This study investigated neurodevelopmental pathways to children's general and specific mathematic abilities across the full gestational age range. STUDY...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.07.015
更新日期：2014-10-01 00:00:00
