Abstract:
:The evolution of ultrasound findings in 59 infants with transient periventricular densities is described and the neurodevelopmental outcome of 53 of these infants was compared with 92 of 107 infants with normal ultrasound scans, born during the same 24-month period. Four of the 53 infants with transient periventricular densities developed spastic diplegia and 24 developed transient dystonia, whereas only 8 of the 92 children with normal ultrasound scans demonstrated this finding (P less than 0.001). Persistence of the densities for more than 10 days and the presence of densities in the trigone were especially related with subsequent problems. Postmortem findings in two infants and MRI studies in six infants also suggested that transient periventricular densities represent the milder end of the spectrum of periventricular leukomalacia.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
De Vries LS,Regev R,Pennock JM,Wigglesworth JS,Dubowitz LMdoi
10.1016/0378-3782(88)90103-xsubject
Has Abstractpub_date
1988-03-01 00:00:00pages
225-33issue
2-3eissn
0378-3782issn
1872-6232pii
0378-3782(88)90103-Xjournal_volume
16pub_type
杂志文章abstract::A multicenter randomised trial was conducted in nine neonatal centers in Japan to re-evaluate the safety and the efficacy of high frequency oscillatory ventilation using the piston type oscillator (Hummingbird) in the treatment of respiratory failure in preterm infants weighing between 750 and 2000 g at birth. A total...
journal_title:Early human development
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/0378-3782(93)90088-c
更新日期:1993-02-01 00:00:00
abstract:BACKGROUND:Angiogenesis, a critical process for growth and development is altered in intrauterine growth restriction (IUGR). Vascular endothelial growth factor (VEGF) and its receptors VEGFR-1, soluble (s) VEGFR-1 and VEGFR-2 represent a regulatory system, essential for both physiological and pathological angiogenesis....
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.09.010
更新日期:2006-04-01 00:00:00
abstract:OBJECTIVE:A short course of moderately early dexamethasone therapy with a starting dose of 0.5 mg/kg/day improves lung compliance and shortens the duration of ventilatory support in preterm infants with respiratory distress syndrome (RDS). We conducted a double-blind, randomized study to evaluate whether a moderately e...
journal_title:Early human development
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-3782(03)00082-3
更新日期:2003-10-01 00:00:00
abstract::The relative role of perinatal factors (birthweight, gestational age, gender, asphyxia, mechanical ventilation and cerebral lesions), developmental factors (neuromotor development during the first 18 months of life) and environmental factors (socio-economic status and bilingualism) on cognitive abilities was evaluated...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(95)01673-2
更新日期:1995-10-02 00:00:00
abstract::Psychobiological studies of fetal ontogenesis in non-human species, particularly in laboratory rat, now have much to offer students of human development. Psychobiological approaches are 'ecologically' oriented which, for fetal research, implies consideration of the adaptive significance of behavior within the uterine ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/0378-3782(93)90102-z
更新日期:1993-12-31 00:00:00
abstract:BACKGROUND:Physical and emotional parent-infant closeness activate important neurobiological mechanisms involved in parenting. In a neonatal care context, most research focuses on physical (parental presence, skin-to-skin contact) aspects; insights into emotional closeness can be masked by findings that overemphasise t...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2020.105155
更新日期:2020-10-01 00:00:00
abstract::Whenever possible, oral feeding is the preferred method in neonatal feeding. However, many premature infants are unable to suck and swallow effectively; in these cases alternative methods of nutrient delivery must be used. We briefly review the different feeding methods used in neonatal units, with particular attentio...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/S0378-3782(12)70011-7
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Fetal cells exfoliate in the uterine cavity during early pregnancy and are a potential source of material for NIPD. AIMS:This study was designed to test the hypothesis that fetal cells obtained from the uterine cervix during the first trimester of pregnancy could be utilized for prenatal diagnosis of chromo...
journal_title:Early human development
pub_type: 临床试验,杂志文章
doi:10.1016/j.earlhumdev.2010.04.005
更新日期:2010-05-01 00:00:00
abstract::In the scholarly environment, research findings are disseminated as journal papers which support/dispute extant knowledge or add further to what is already known. The entire manuscript needs to be cited (in-text) and referenced (at the end of article), in order for readers to ascertain the validity of the research cla...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.09.012
更新日期:2019-01-01 00:00:00
abstract::The calculation of descriptive statistics includes the calculation of standard error and confidence interval, an inevitable component of data analysis in inferential statistics. This paper provides pointers as to how to do this in Microsoft Excel™. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.01.013
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:An increased risk of major congenital abnormalities after IVF and ICSI has been described, but underlying mechanisms are unclear. This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.06.002
更新日期:2012-10-01 00:00:00
abstract::In the infant, sucking behaviour is one of the first coordinated muscular activities. It is under the control of the brainstem. In utero sucking is observed from 13 weeks' gestation. The healthy full-term newborn infant has a very stable rhythm of alternating bursts of sucking with pauses in between. The non-nutritive...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00091-8
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Obstetrical and neonatal complications and/or an adverse parenting environment are risk factors for language impairment, but little is known about their effects on early word production (late talking). AIMS:To determine obstetrical and neonatal risk factors in children with delayed word production; to asses...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.05.009
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To compare measurements of the upper arm cross-sectional areas (total arm area, arm muscle area, and arm fat area of healthy neonates) as calculated using anthropometry with the values obtained by ultrasonography. MATERIALS AND METHODS:This study was performed on 60 consecutively born healthy neonates: gesta...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00085-1
更新日期:1999-03-01 00:00:00
abstract::ELISA methods were used to determine the concentrations of CAI and CAII in spermatozoa, seminal plasma, ovarian follicular fluid, decidual tissues, chorionic villi and various fetal tissues at 8-11 weeks gestation. Both CAI and CAII were expressed in all subjects except ovarian follicular fluid samples. The possible p...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00119-9
更新日期:1998-07-10 00:00:00
abstract::Discrepancies between active and passive muscle power are often seen in pre-term infants over the first year. Generally of a transient nature, they are most obvious in the extensor muscles of the trunk where there is a high active muscle power relative to the passive component. While high active muscle power may not b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(95)01661-l
更新日期:1995-08-30 00:00:00
abstract:BACKGROUND AND AIM:To investigate whether neonates with prenatally detected congenital heart defects (CHD) demonstrate cerebral abnormalities on early preoperative cranial ultrasound (CUS), compared to healthy neonates, and to measure brain structures to assess brain growth and development in both groups. STUDY DESIGN...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105097
更新日期:2020-09-01 00:00:00
abstract::It is convenient to calculate milk energy from the creamatocrit but in order to assess the accuracy with which energy content can be predicted in this way, the creamatocrit, the percentage of carbon, and the calorie value of milk were determined in 11 samples of pooled pasteurised human milk. The calculated milk energ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90121-5
更新日期:1985-05-01 00:00:00
abstract:UNLABELLED:While the role of antiepileptic drug (AED) therapy in teratogenesis has widely been investigated, there are few prospective studies on later postnatal development in offspring of epileptic women in utero exposed. The aim of this study was a prospective investigation of the psychomotor development in a select...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(03)00083-5
更新日期:2003-11-01 00:00:00
abstract:INTRODUCTION:Sensitive screening for phenylketonuria (PKU) and other disorders requires accurate measurement of analytes in blood eluted from filter paper. The development of new quantitative methods for phenylalanine measurement in dried blood spots for PKU screening has introduced an increased number of calibrators p...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(96)01762-8
更新日期:1996-07-19 00:00:00
abstract::The levels of growth hormone, vasopressin, prolactin, calcitonin, gastrin, insulin, epinephrine, norepinephrine and dopamine were measured in six lactating women during breast feeding. Prolactin levels increased in response to suckling as expected. In addition, insulin levels rose two-fold. No consistent changes were ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90117-8
更新日期:1984-09-01 00:00:00
abstract::Twenty-seven 5--8-day-old babies were filmed during normal breast feeding (one feed each). Sucking patterns were determined from the film from a total sample of 17,676 sucks. Intersuck interals fell on two distributions: one of intervals between sucks during bursts of sucking (1.3 sec and less), and the other of rests...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(79)90042-2
更新日期:1979-12-01 00:00:00
abstract::The diagnosis, acute management and follow-up of neonates with haemolytic disease of the newborn (HDN) still represents a significant area of activity for maternity/neonatal services. ABO incompatability is now the single largest cause of HDN in the western world. However, with increasing knowledge at the molecular le...
journal_title:Early human development
pub_type: 杂志文章,实务指引,评审
doi:10.1016/j.earlhumdev.2008.06.005
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.01.006
更新日期:2014-03-01 00:00:00
abstract::Cardiovascular malformations are frequently associated in patients with esophageal atresia (EA). We observed azygos continuation mimicking an aortic arch anomaly in four newborns with type III EA. They presented concomitant rib anomalies indicating a common developmental defect. Foreknowledge is important for planning...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2017.05.007
更新日期:2017-08-01 00:00:00
abstract:INTRODUCTION:Reduced left ventricular (LV) diastolic function can exert significant load to the right ventricle (RV) that can affect RV-pulmonary vasculature (PV) coupling. RV-PV can be assessed with the RV length-force relationship (tricuspid annular plane systolic excursion [TAPSE] to pulmonary artery acceleration ti...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.11.006
更新日期:2019-01-01 00:00:00
abstract::To learn if chemoreceptor control of breathing is abnormal in babies whose mothers took narcotics, cocaine, or both drugs during pregnancy, we performed hypoxia and hypercapnia challenges on 28 babies (greater than or equal to 36 weeks gestation). Six babies were exposed to narcotics, six to cocaine, nine to both drug...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(91)90193-7
更新日期:1991-12-01 00:00:00
abstract:BACKGROUND:Despite its prevalence and potential maternal and neonatal implications, the literature on the thickness levels of meconium stained amniotic fluid (MSAF) and its impact on neonatal outcomes is relatively outdated and relies on relatively small sample sizes. AIMS:To study if different thickness levels of MSA...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.104953
更新日期:2020-03-01 00:00:00
abstract::Anti-müllerian hormone (AMH) is a glycoprotein produced by immature Sertoli cells and responsible for the regression of müllerian ducts in male fetuses. The ontogeny of the hormone in early human development was investigated. While no detectable AMH could be found in female fetal serum, in males, the mean +/- S.E.M. A...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(93)90204-8
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND:Long-lasting respiratory symptoms have a huge impact on the quality of life in prematurely born children. AIMS:We aimed to investigate the perinatal and maternal risk factors involved in the development of chronic respiratory morbidity in preterm infants, with an emphasis on the importance of Foetal Inflamm...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.07.002
更新日期:2014-09-01 00:00:00