Abstract：
:Anti-müllerian hormone (AMH) is a glycoprotein produced by immature Sertoli cells and responsible for the regression of müllerian ducts in male fetuses. The ontogeny of the hormone in early human development was investigated. While no detectable AMH could be found in female fetal serum, in males, the mean +/- S.E.M. AMH serum concentration was 40.5 +/- 3.9 ng/ml from 19 to 30 weeks (n = 13), and 28.4 +/- 6.1 ng/ml from 30 weeks to term (n = 9). The latter value is significantly different from the mean AMH concentration in serum from boys aged 2 months to 2 years (43.1 +/- 3.7), suggesting that AMH production is sluggish during the perinatal period. The serum AMH concentration of a 46,XX male fetus was in the normal range for males. Using in situ hybridization, AMH transcripts were detected in the testicular tissue of all fetuses from 8 weeks onwards, but not in fetal ovaries nor in the yet undifferentiated gonadal tissue of a 7-week-old fetus bearing male-determining DNA sequences. Together, these data indicate that AMH is a reliable marker for the presence of functional testicular tissue and, as such, may be helpful for the diagnosis of fetal sex, particularly in the presence of sex chromosome abnormalities.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Josso N,Lamarre I,Picard JY,Berta P,Davies N,Morichon N,Peschanski M,Jeny Rdoi
10.1016/0378-3782(93)90204-8subject
Has Abstractpub_date
1993-06-01 00:00:00pages
91-9issue
2eissn
0378-3782issn
1872-6232pii
0378-3782(93)90204-8journal_volume
33pub_type
杂志文章abstract：AIMS:To study longitudinal growth pattern of head circumference of full-term symmetric and asymmetric small for gestational age (SGA) infants of the two sexes during first year of life. STUDY DESIGN:Mixed-longitudinal growth research design. SUBJECTS:Head circumference amongst full-term 100 symmetric, 100 asymmetric ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.11.007
更新日期：2012-07-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：:221 small-for-dates (SFD) and 244 average-for-dates (AFD) children were personally examined at birth, and seen thereafter at regular intervals up to 4 years, when a thorough assessment was made. There was an excess of SFD children with major congenital abnormalities; but no difference between the groups in the number ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90007-5
更新日期：1983-10-01 00:00:00
abstract：BACKGROUND:Recent evidence suggests that cord insertion type of one twin correlates with chorionic plate vascularization of the monochorionic co-twin. Specifically, for twins with paracentral cords, chorionic plate vascularization is significantly greater when the co-twin has a velamentous, rather than paracentral cord...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.01.009
更新日期：2013-04-01 00:00:00
abstract：UNLABELLED:During the previous two decades smoking among pregnant women in the developed world declined by about 60-75%. Nevertheless, prenatal smoking remains a common habit and accounts for a significant proportion of fetal morbidity and mortality through both a direct (fetal) and an indirect (placental) effect. The ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2007.08.002
更新日期：2007-11-01 00:00:00
abstract：AIM:The effects of intestinal bifidobacteria on the development of immunity in early life were explored. METHODS:Neonatal SD rats born and housed under strict barrier systems were fed from birth with sufficient antibiotics (bifidobacteria minimisation group) or supplemented daily with 1x10(10) colony-forming units of ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.01.002
更新日期：2010-01-01 00:00:00
abstract：:This study documents the longitudinal development of head control in 104 infants born at 25-33 weeks gestation. Protective side turning of the head was found to have a developmental sequence of reducing spinal extension. In the 93 infants with normal motor outcome, individual differences in the rate of development cor...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90074-x
更新日期：1985-09-01 00:00:00
abstract：:Discrepancies between active and passive muscle power are often seen in pre-term infants over the first year. Generally of a transient nature, they are most obvious in the extensor muscles of the trunk where there is a high active muscle power relative to the passive component. While high active muscle power may not b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01661-l
更新日期：1995-08-30 00:00:00
abstract：:Children born preterm are at risk for later developmental disorders. The present study examined the predictive effects of neonatal, sociodemographic, and temperament characteristics on behavioral outcomes at toddlerhood, in children born preterm. The sample included 100 toddlers born preterm and with very-low-birth-we...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.09.015
更新日期：2016-12-01 00:00:00
abstract：:In this study of 167 neonates who demonstrated a total of 1010 transitions between arousal states, we considered whether specific state transitions were associated with umbilical cord blood lead levels. We found that the arousal patterns of neonates with varying levels (<1, 1-10 and >10 microg/dL) of lead exposure cou...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.06.002
更新日期：2008-04-01 00:00:00
abstract：:28 polygraphic recordings were made in normal infants: 20 in full-term newborns and 8 in 2- to 10-wk-old babies. In full-term newborns sighs and apneas (greater than 5 sec) were significantly more numerous in active (REM) sleep, while startles prevailed in quiet (NREM) sleep. The incidence of all these events diminish...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(78)90051-8
更新日期：1978-04-01 00:00:00
abstract：:In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90140-e
更新日期：1990-11-01 00:00:00
abstract：:Low nephron endowment secondary to intrauterine growth restriction (IUGR) results in compensatory hypertrophy of the remaining glomeruli, which in turn is associated with hypertension. However, gender differences exist in the response of the kidney to injury, and IUGR female offspring seems protected from an unfavorab...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.12.015
更新日期：2009-06-01 00:00:00
abstract：AIM:Depression during pregnancy is a significant cause of adverse birth outcomes, and its prevalence has increased in recent years. This study aimed to give an updated quantification of the risk of preterm birth (PTB), low birth weight (LBW) and intrauterine growth restriction (IUGR) that is associated with antenatal d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105243
更新日期：2021-01-01 00:00:00
abstract：:The effect of type-I diabetes on the quality of general movements (GMs) was studied longitudinally in 12 human fetuses. GMs were analysed at two-weekly intervals from 16 weeks until delivery. A pregnancy optimality-score and a diabetes optimality-score were used to cover the course of the pregnancy and delivery and th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00089-3
更新日期：1997-11-24 00:00:00
abstract：OBJECTIVES:To determine whether early mortality (first year of life) risks among small for gestational age (SGA) neonates were similar regardless of SGA subtype based on three chronological classifications (term, preterm and post-term). STUDY DESIGN:Retrospective cohort study on all singleton live births in the United...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.05.008
更新日期：2007-02-01 00:00:00
abstract：:There is increasing evidence that sleep plays a major role in the development of neural pathways in the neonatal brain. Several studies have suggested evidence-based approaches to improve sleep for infants admitted to the neonatal intensive care unit (NICU); however, in many neonatal centers very few of these strategi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2017.07.002
更新日期：2017-10-01 00:00:00
abstract：:Dramatic improvements have occurred in the overall health of our children driven by rigorous research translated into clinical practice. However, all is not well for too many, not only for their health but for other outcomes of their lives. These outcomes reflect poorly on how professional groups in child life and hea...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2014.08.022
更新日期：2014-11-01 00:00:00
abstract：:A cohort study was carried out to assess the association between glucose-6-phosphate dehydrogenase (G6PD) deficiency, diagnosed by quantitative enzyme assay, and neonatal hyperbilirubinemia, defined as serum total bilirubin >/=15 mg/dl, in the well-baby nursery of Chang Gung Children's Hospital. Among 42,110 inborn in...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(03)00002-1
更新日期：2003-04-01 00:00:00
abstract：AIM:This study examined the rates of follow-up for a cohort of extremely preterm (EP -<28weeks gestation) and/or extremely low birthweight (ELBW -<1000g) children at two years with related perinatal and geographical factors. The secondary aim was to determine the rates of developmental delay and disability. METHODS:A ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.09.012
更新日期：2015-12-01 00:00:00
abstract：:Newborn infants, especially preterm infants, have an immature immune system, which is not capable to actively protect against vaccine-preventable infections. Therefore, the newborn is dependent on transplacental transport of Immunoglobulin G (IgG), an active, FcRn receptor mediated process. Fetal IgG rises from approx...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2010.11.003
更新日期：2011-02-01 00:00:00
abstract：:Eleven healthy fetuses between 36 and 39 weeks of gestation were studied during the active sleep state to examine effects of a 5-s vibratory acoustic stimulus on the baseline fetal heart rate and flow velocity waveform in the fetal internal carotid artery. There was an immediate marked rise in baseline fetal heart rat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(89)90105-9
更新日期：1989-04-01 00:00:00
abstract：:The world's literature has been scoured to obtain data on 492 examples of the fetal alcohol syndrome (FAS) in the Northern Hemisphere. The seasonally pattern of FAS birth prevalence rates is compared with the seasonality pattern of ethanol intakes to estimate the time-lag between them and hence the timing of ethanol d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90065-8
更新日期：1983-07-01 00:00:00
abstract：:The objective of this work was to examine the changes in the fatty acid profiles of plasma lipid fractions and red blood cell membrane phospholipids in newborn infants during the first 6-8 h of life. Methyl esters of fatty acids from plasma free fatty acids and phospholipids and from membrane phosphatidylethanolamine,...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90041-7
更新日期：1987-03-01 00:00:00
abstract：:The aim is to know whether antenatal olfactory learning have a greater effect than postnatal olfactory learning on infant feeding even in the absence of triggering signals. We evaluated the sucking behavior of infants completely separated from their mothers for 10-14 days since birth. The 12 infants admitted to Chiba ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.10.003
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.006
更新日期：2014-03-01 00:00:00
abstract：OBJECTIVE:We evaluated the effect of maternal administration of betamethasone (0.2 mg/kg per day) on mitogen-induced lymphocyte proliferation and interleukin-2 (IL-2) production by maternal, fetal, and neonatal rat splenic lymphocytes. STUDY DESIGN:Betamethasone was injected intramuscularly on days 19 and 20 of gestat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90028-0
更新日期：1994-01-01 00:00:00
abstract：OBJECTIVE:To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS:Eighty-one preterm infants b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.12.008
更新日期：2018-02-01 00:00:00
abstract：:The mediating effect of maternal self-efficacy in the association between locus of control and anxiety, among mothers of hospitalized babies in the Neonatal Intensive Care Unit (NICU) was examined. Findings confirmed partial mediation effect suggesting that professionals can contribute to the reduction of levels of an...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105284
更新日期：2021-01-01 00:00:00
abstract：:Apnea of prematurity and gastroesophageal reflux (GER) are both common occurrences in preterm infants and widely perceived to be causally related. We seek in this review to provide a potential guideline for neonatal GER non-pharmacologic and pharmacologic therapy. Available physiologic data suggest that when there is ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(13)70005-7
更新日期：2013-06-01 00:00:00
