Abstract：
:The effect of type-I diabetes on the quality of general movements (GMs) was studied longitudinally in 12 human fetuses. GMs were analysed at two-weekly intervals from 16 weeks until delivery. A pregnancy optimality-score and a diabetes optimality-score were used to cover the course of the pregnancy and delivery and the severity of diabetes. GMs of infants were analysed 1, 4-6, and 12-18 weeks after birth and the Bayley developmental test was performed at 10 months. All fetuses showed normal GMs at 16 weeks. From 20 weeks onwards until delivery five fetuses developed abnormal GMs. The diabetes optimality-score was significantly lower in the group with abnormal GMs (P = 0.018) whereas the pregnancy optimality-score did not differ between fetuses with normal and abnormal GMs. Our results indicate that type-I diabetes can have a negative impact on prenatally observed GMs. Consistently normal GMs indicate normal neurodevelopmental outcome at 10 months whereas in the group with abnormal GMs reduced Bayley-scores may occur.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Kainer F,Prechtl HF,Engele H,Einspieler Cdoi
10.1016/s0378-3782(97)00089-3subject
Has Abstractpub_date
1997-11-24 00:00:00pages
13-25issue
1eissn
0378-3782issn
1872-6232pii
S0378378297000893journal_volume
50pub_type
杂志文章abstract：BACKGROUND:Pregnancy and delivery are complex processes, and isolated obstetric complications rare and often accompanied or followed by a number of others. AIMS:To study the relationship between the overall obstetric situation (as opposed to single obstetric risk factors) and emotional and substance use disorders in y...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.04.016
更新日期：2004-11-01 00:00:00
abstract：:The structural changes in the umbilical cord of full term fetuses from 18 cases of gestational diabetes were studied. All these were insulin-dependent and their blood glucose levels were well controlled. Light microscopy showed rupture and erosion of the endothelial lining of umbilical arteries resulting in increased ...
journal_title：Early human development
pub_type： 杂志文章
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更新日期：1986-10-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：2011-06-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：1989-04-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：2016-12-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：1988-03-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章,评审
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更新日期：2005-02-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：2011-11-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：1985-05-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：1982-04-01 00:00:00
abstract：BACKGROUND:Routine oropharyngeal suctioning in term vigorous neonates immediately after birth is a questionable practice. Current recommendations favor suctioning only in the presence of considerable obstruction due to secretions, blood or other matter. We aimed to analyze the influence of oropharyngeal suctioning on c...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.01.005
更新日期：2015-02-01 00:00:00
abstract：:The behavior exhibited by human fathers at their first contact with the young was studied on 15 fathers of full-term infants delivered by cesarean section. The naked infant was presented to the father approximately 15 min after delivery, and photographs were taken every second during the first 7 min of contact. An ord...
journal_title：Early human development
pub_type： 杂志文章
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更新日期：1979-03-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(93)90045-v
更新日期：1993-09-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.08.017
更新日期：2003-12-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00121-3
更新日期：2001-01-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2006.09.018
更新日期：2006-12-01 00:00:00
abstract：BACKGROUND:Previous studies suggest that RhD positive heterozygotes express better health status than RhD positive homozygotes and especially RhD negative subjects. This also applies to pregnant women. According to the Trivers-Willard hypothesis, women in better physical condition should have more sons. AIM:To test th...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2019.104864
更新日期：2020-01-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90065-8
更新日期：1983-07-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/0378-3782(93)90102-z
更新日期：1993-12-31 00:00:00
abstract：BACKGROUND:The assessment of the quality of general movements (GMs) in young infants is a reliable and valid diagnostic tool for detecting brain dysfunction early in life. Of special interest is a type of GMs called fidgety movements (FMs) characteristic for 3- to 5-month-old infants. GMs are part of an infant's sponta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.01.004
更新日期：2004-04-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(13)70005-7
更新日期：2013-06-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.104829
更新日期：2019-10-01 00:00:00
abstract：INTRODUCTION:Little is known about sex differences in human fetal heart and behaviour. PATIENTS AND METHODS:One hundred twenty-three nulliparous healthy women carrying a male (n=56) or female (n=67) fetus participated in this study. All pregnancies remained uncomplicated and delivery was uneventful. Ultrasound observa...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(03)00047-1
更新日期：2003-08-01 00:00:00
abstract：:Gastro-oesophageal reflux (GOR) and gastro-oesophageal reflux disease (GORD) occur frequently during the first months of life. Gastro-oesophageal reflux may be a primary gastro-intestinal motility disorder, but it may also be secondary to other conditions such as cow's milk protein allergy. Objective diagnosis can be ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2005.10.011
更新日期：2005-12-01 00:00:00
abstract：BACKGROUND:Kangaroo care, i.e., skin-to-skin cohabitation (SSC) between an infant and caregiver, is often used in neonatal intensive care units to promote bonding, breastfeeding and infant growth. The direct salutary effects of SSC on cardio-respiratory control in preterm infants remain equivocal; some reports suggest ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.08.015
更新日期：2014-12-01 00:00:00
abstract：INTRODUCTION:COVID-19 is pandemic. International travel bans in March 2020 dampened viral spread and resulted in an overnight global economic crisis. As countries ease travel and social distancing restrictions, viral resurgences are expected. This study was carried out in order to delineate the development of a second ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105211
更新日期：2020-10-03 00:00:00
abstract：BACKGROUND:Mothers have been shown to have higher morning cortisol on days they go to work compared to non-workdays; however, it is unknown how maternal workday associates with child morning cortisol or the attunement of mother-child morning cortisol. AIMS:This study examined the presence and stability of morning cort...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.11.007
更新日期：2014-01-01 00:00:00
abstract：:The validity of the Wigglesworth experimental model to produce newborn rats that are small for gestational age by ligation of one of both uterine vessels was confirmed. Newborn rats from the opposite horns are used as controls in the classical model. It is concluded from this study that newborns from sham-operated dam...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(79)90038-0
更新日期：1979-09-01 00:00:00
abstract：BACKGROUND:Transcutaneous bilirubin (TcB) measurement is widely used as screening for neonatal hyperbilirubinaemia. AIMS:To prospectively validate TcB measurement using hour-specific nomogram in identifying newborn infants not at risk for severe hyperbilirubinaemia. STUDY DESIGN:prospective, observational, multicente...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2011.07.001
更新日期：2012-01-01 00:00:00
