Abstract:
:Gastro-oesophageal reflux (GOR) and gastro-oesophageal reflux disease (GORD) occur frequently during the first months of life. Gastro-oesophageal reflux may be a primary gastro-intestinal motility disorder, but it may also be secondary to other conditions such as cow's milk protein allergy. Objective diagnosis can be difficult because there may be absence of correlation between history, results of pH monitoring and histology. Severe GORD may cause minor symptoms, and minor GOR may cause severe symptoms. Several different therapeutic interventions exist. Simply stated, thickened formula reduces regurgitation and alginates and proton pump inhibitors can be used to decrease acid GOR, depending on the severity of the GORD. Efficacy data of prokinetic drugs are either lacking or disappointing. Regarding side-effects, interest has been focused on cisapride, although other molecules have similar effects. Long-term side-effects such as the nutritional consequence of therapeutic management have been insufficiently studied, especially for the acid-reducing molecules.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Vandenplas Y,Salvatore S,Hauser Bdoi
10.1016/j.earlhumdev.2005.10.011keywords:
subject
Has Abstractpub_date
2005-12-01 00:00:00pages
1011-24issue
12eissn
0378-3782issn
1872-6232pii
S0378-3782(05)00202-1journal_volume
81pub_type
杂志文章,评审abstract:OBJECTIVE:Maternal smoking during pregnancy is associated with a reduction in birth size but very few studies have collated changes in neonatal anthropometry. Our aims were both to assess body composition differences by anthropometry between new-borns from smoking mothers and those from non-smoking mothers, and to show...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.07.015
更新日期:2012-03-01 00:00:00
abstract:OBJECTIVE:To determine whether placental lesions are risk factors for neurologic morbidities in intrauterine growth restricted (IUGR) infants, we compared the incidence of cranial ultrasound (CUS) abnormalities and the number and type of placental lesions in IUGR cases and gestational age-matched appropriate for gestat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(01)00114-1
更新日期:2001-04-01 00:00:00
abstract::Ultrastructural and immunohistochemical studies were made of the testicular interstitial tissue from eight human fetuses of 15 to 27 weeks gestation. Three cell types developed in mesenchymal cells: Leydig cells and peritubular cells, as already reported, and cells of the mononuclear phagocyte system (MPS), which are ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(89)90070-4
更新日期:1989-09-01 00:00:00
abstract::We studied the ontogeny and temporal organization of non-nutritive sucking during active sleep in 6 healthy preterm infants (mean birthweight 1.1 kg (range 0.8-1.3 kg) gestational age 28.6 weeks (range 26-30 w] from 30 to 35 weeks of post-menstrual (PM) age. Recognizable rhythmical sucking bursts were recorded at 28 w...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90100-8
更新日期:1985-07-01 00:00:00
abstract::Relationships between maternal factors associated with very slow and very fast fetal growth rate, and the postnatal growth patterns within groups of 238 small-for-dates (SFD) and 241 large-for-dates (LFD) children were examined. Within the SFD group significant differences were found in their weight, height, and to a ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90036-6
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Kangaroo care, i.e., skin-to-skin cohabitation (SSC) between an infant and caregiver, is often used in neonatal intensive care units to promote bonding, breastfeeding and infant growth. The direct salutary effects of SSC on cardio-respiratory control in preterm infants remain equivocal; some reports suggest ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.08.015
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Pregnancy and delivery are complex processes, and isolated obstetric complications rare and often accompanied or followed by a number of others. AIMS:To study the relationship between the overall obstetric situation (as opposed to single obstetric risk factors) and emotional and substance use disorders in y...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.04.016
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:Zinc and copper are essential for preterm infants, but recommended requirements from different groups vary widely. Recommended zinc intakes have steadily increased over the years. Although this would be expected to impair copper absorption, recommended copper intakes have not risen in parallel. OBJECTIVES:T...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2013.08.001
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Prior studies have shown that children with congenital hearing loss have increased rates of behavior disorders. Child hearing loss has also been reported to be associated with increased maternal stress. Little is known about the behavior or the predictors of behavioral outcomes of children with hearing loss ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.06.006
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Controversy exists regarding association of high levels of proinflammatory cytokines, neonatal morbidities and poor neurodevelopment outcome in very low birth weight infants. OBJECTIVE:To determine association between severity of early inflammatory response and neurodevelopment outcome in high risk very low...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.03.009
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Tyrosine hydroxylase (TH) is a specific marker for catecholaminergic neurones. Some reports have demonstrated a decrease of TH in the Sudden Infant Death Syndrome (SIDS) compared with controls. To further investigate this, the correlation between TH and sleep apnea was investigated here. MATERIALS AND METHO...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.08.007
更新日期:2003-12-01 00:00:00
abstract::Slide show presentations have become integral to the workplace, and PowerPoint is ubiquitous since it ships with the Microsoft Office Suite. However, the increasing sophistication of such software may encourage presenters to privilege form over content. It is possible to apply scientific research from Educational Psyc...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.06.006
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Children with major anatomical congenital anomalies (CA) often need prolonged hospitalization with surgical interventions in the neonatal period and thereafter. Better intensive care treatment has reduced mortality rates, but at the cost of more morbidity. AIM:To study motor-function and exercise capacity i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.06.014
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Intrauterine growth restriction (IUGR) is a fetal condition characterized by growth-rate reduction. Afflicted fetuses tend to display abnormalities in heart rate. OBJECTIVE:To study the differences in the heart-rate variability of low-risk fetuses and IUGR fetuses during different behavioral states. METHOD...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.07.002
更新日期:2013-10-01 00:00:00
abstract::It is becoming increasingly apparent that pyridoxine responsive homocystinuria patients are being missed by newborn screening programs. The possibility that screening for homocystine, rather than the methionine, might be more effective was investigated by comparing homocystine and methionine levels of non-responsive p...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(96)01860-9
更新日期:1997-04-25 00:00:00
abstract:BACKGROUND:Previous studies have reported an increased incidence of thyroid dysfunction in premature/low birth weight infants. The cord blood concentrations of transthyretin (TTR), a thyroid hormone binding protein, have also been found to be decreased in preterm infants. While thyroid hormone concentrations are decrea...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2008.01.001
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Children born preterm are known to be at risk for neurodevelopmental disorders. The role of perinatal asphyxia in this increased risk is still a matter of debate. AIM:To analyze the contribution of perinatal asphyxia in a population of preterm infants admitted to a secondary paediatric setting to neurologic...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.06.003
更新日期:2010-07-01 00:00:00
abstract::This study examined the risk factors for respiratory distress syndrome (RDS) in preterm infants from pregnancies complicated by placenta previa. Forty preterm infants born to mothers with placenta previa between January 1989 and December 1995 in a medical center were enrolled. Each of these patients was matched in ges...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00121-3
更新日期:2001-01-01 00:00:00
abstract::ELISA methods were used to determine the concentrations of CAI and CAII in spermatozoa, seminal plasma, ovarian follicular fluid, decidual tissues, chorionic villi and various fetal tissues at 8-11 weeks gestation. Both CAI and CAII were expressed in all subjects except ovarian follicular fluid samples. The possible p...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00119-9
更新日期:1998-07-10 00:00:00
abstract:BACKGROUND:Retinopathy of prematurity (ROP) is often associated with visual impairment and multiple developmental disabilities. AIMS:As most of the previous studies include infants with brain lesions, that can determine visual impairment per se, a cohort of low neurological risk preterm infants without ROP and with va...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105134
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Controversial results have been reported on the effect of type of feeding on the level of fecal calprotectin in infants. OBJECTIVE:To assess fecal calprotectin levels in breast fed or nonbreast fed healthy infants. DESIGN:A study was conducted to compare fecal calprotectin in infants who were exclusively b...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.06.005
更新日期:2014-09-01 00:00:00
abstract:AIMS:To determine the reproducibility and minimum detectable change (MDC) of heart rate variability (HRV) measures during two sequential 24-h periods, at week 32 of gestation, in preterm infants born between 28 and 32 weeks, hospitalized in the neonatal intensive care unit (NICU). The second aim is to assess postnatal ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105117
更新日期:2020-09-01 00:00:00
abstract::We have investigated infant-caregiver interactions in an isolated African subsistence farming community where women perform arduous agricultural tasks in addition to their normal domestic duties which include child care. 49 babies aged 3-18 months were studied on one or two occasions. Detailed observations were made o...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90139-2
更新日期:1985-10-01 00:00:00
abstract:BACKGROUND:Preterm children are at risk for executive function (EF) problems, which have been linked to behavior and learning problems in full term children. In this study, we examine the relationship between EF and functional outcomes in preterm children. AIM:To evaluate (1) EF skills of 9- to 16-year-old children bo...
journal_title:Early human development
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.earlhumdev.2011.07.018
更新日期:2012-02-01 00:00:00
abstract::Interfacility transport to tertiary care for high-risk neonates has become an integral part of equitable access to optimal perinatal healthcare. Excellence in clinical care requires expertise in transport medicine and the coordination of safe transport processes. However, concerns remain regarding environmental stress...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2020.105051
更新日期:2020-07-01 00:00:00
abstract::We assessed the relation of perinatal factors to severe hypothyroxinemia of prematurity, defined as thyroxine value more than 2.6 standard deviations below the mean for newborns. The 365 survivors of birth before 32 weeks gestation were enrolled in a population-based study of the correlates of neonatal brain injury. I...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(96)01843-9
更新日期:1997-01-20 00:00:00
abstract::Twenty-four term infants with disproportionate intrauterine growth retardation (SGA group) and 24 normally grown term infants matched for age, sex, birth rank and social class were followed from birth until 7 years of age. Both groups were free from perinatal complications and chronic diseases. The children in the SGA...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90038-2
更新日期:1988-11-01 00:00:00
abstract:INTRODUCTION:Little is known about sex differences in human fetal heart and behaviour. PATIENTS AND METHODS:One hundred twenty-three nulliparous healthy women carrying a male (n=56) or female (n=67) fetus participated in this study. All pregnancies remained uncomplicated and delivery was uneventful. Ultrasound observa...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(03)00047-1
更新日期:2003-08-01 00:00:00
abstract:INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.08.009
更新日期:2013-02-01 00:00:00
abstract::Six month infant-mother interaction patterns were observed and 10 month Bayley MDI scores were obtained in 10 fullterm and 14 healthy preterm (less than 37 weeks) infants. Relationships among interaction parameters and intellectual performance are compared with those among earlier interaction patterns and development....
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(86)90008-3
更新日期:1986-04-01 00:00:00