Abstract:
OBJECTIVE:Maternal smoking during pregnancy is associated with a reduction in birth size but very few studies have collated changes in neonatal anthropometry. Our aims were both to assess body composition differences by anthropometry between new-borns from smoking mothers and those from non-smoking mothers, and to show whether these differences affect proportional body mass distribution. METHODS:Caucasian mothers and their full term singleton new-borns (N=1216) were selected during 2009. A structured questionnaire was completed regarding obstetric and demographic data, as well as tobacco consumption. Women were categorized, according to their smoking habits, into a non-smoking group (never smoked or stopped smoking prior to pregnancy) and a smoking group (smoked throughout pregnancy). RESULTS:22.1% of mothers smoked during pregnancy (median: 6 cigarettes/day, range: l-40). Smoking mothers were significantly younger than non-smoking mothers but there were no differences regarding other aspects which could affect infant weight. Infants from non-smoking mothers were heavier, longer, and body circumferences were all larger than those from smoking mothers (p<0.001), but the Ponderal Index showed no statistical differences. Skinfold thicknesses were significantly lower in new-borns from smoking mothers but these differences were less evident than those from body size. Subcutaneous fat distribution did not show statistical differences between the two groups. After gestational age, to smoke during gestation is the second main determinant of birth weight. CONCLUSIONS:Smoking during pregnancy involves a generalized reduction of most axiological parameters as a result of proportionate fetal growth impairment. In those infants born from mothers who smoked during gestation, neonatal lean body mass appears to be more affected than body fat, and distribution of subcutaneous fat is not different.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Samper MP,Jiménez-Muro A,Nerín I,Marqueta A,Ventura P,Rodríguez Gdoi
10.1016/j.earlhumdev.2011.07.015subject
Has Abstractpub_date
2012-03-01 00:00:00pages
141-5issue
3eissn
0378-3782issn
1872-6232pii
S0378-3782(11)00238-6journal_volume
88pub_type
杂志文章abstract:BACKGROUND:Early iron supplementation in women with sufficient reserves could provoke iron excess resulting in haemoconcentration and low infant birth weight (IBW). AIM:To clarify the influence of early iron supplementation on maternal iron status and the IBW, taking into account pre-pregnancy iron deposits. STUDY DE...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.06.003
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.01.006
更新日期:2014-03-01 00:00:00
abstract:INTRODUCTION:In neonates with spina bifida aperta (SBA), leg movements by myotomes caudal to the meningomyelocele (MMC) are transiently observed. It is unclear whether these leg movements relate to functional neural conduction through the MMC. For optimal therapeutical intervention, pathophysiological insight in these ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.09.002
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:The sudden infant death syndrome (SIDS) is still the main cause of postneonatal infant death and its cause is still unknown. Recently, the medullary serotonergic network deficiency theory has been proposed and an association between SIDS and neuronal plasticity has also been suggested. The growth-associated ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.08.017
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Patent ductus arteriosus (PDA) is a frequent problem in preterm infants, and its incidence is inversely correlated with gestational age. The efficacy of medical treatment decreases with decreasing gestational age (GA), and failure rates as well as ductus ligation rates of 40% have been reported in <28 week G...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.06.012
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Testosterone (T) is taken or prescribed to enhance appearance, increase athletic performance and libido and to treat hypogonadism. Digit ratio (2D:4D) is thought to be a negative correlate of prenatal T. Here we consider the relationship between 2D:4D and T supplementation. AIMS:Our sample was taken from th...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.104843
更新日期:2019-12-01 00:00:00
abstract:UNLABELLED:The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1.5 mg/kg, 6 hourly] or placebo was given first over 7 days in a double blind randomized crossover study of 21 preterm infants with feed intolerance. Median [r...
journal_title:Early human development
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-3782(01)00191-8
更新日期:2001-12-01 00:00:00
abstract::Increasing public awareness of the prone sleeping position, maternal smoking and overheating as potentially avoidable risk factors for the sudden infant death syndrome (SIDS) has been accompanied by a dramatic reduction in mortality. The results of two population based studies of SIDS in Avon are compared; the first o...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90208-9
更新日期:1994-09-15 00:00:00
abstract:OBJECTIVE:To evaluate the preschool neurodevelopmental outcome in CDH survivors between 2 and 5 years of age and to identify perinatal and postnatal factors that may be predictive of persistent neurological deficits. METHODS:The study cohort consists of 60 CDH survivors that were enrolled in our prospective, follow-up...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.12.009
更新日期:2013-06-01 00:00:00
abstract::Unlike the defined role of angiotensin-converting enzyme (ACE) gene in adult hypertension, ACE gene did not show direct influence on childhood blood pressure (BP), rather, seemed to be related to childhood growth with age-dependent characteristics. Thus, we examined intermediate effects of postnatal growth between the...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.10.008
更新日期:2012-06-01 00:00:00
abstract::The transitional circulation of the preterm infant differs significantly from the term infant. The preterm infant is uniquely at risk of hypotension and low systemic blood flow states due to failure or delay in the normal transitional circulation processes. The maintenance of normal tissue oxygenation requires mainten...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2005.03.006
更新日期:2005-05-01 00:00:00
abstract::In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(90)90140-e
更新日期:1990-11-01 00:00:00
abstract:AIM:the effect of selective head cooling on cerebral blood flow (CBF) and cerebral metabolism rate (CMR) was investigated in newborn piglets. METHODS:seven days old newborn piglets were randomly assigned to one of the following three groups: Selective head cooling in normal piglets (n=4), selective head cooling after ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.11.007
更新日期:2011-02-01 00:00:00
abstract::The behavior exhibited by human fathers at their first contact with the young was studied on 15 fathers of full-term infants delivered by cesarean section. The naked infant was presented to the father approximately 15 min after delivery, and photographs were taken every second during the first 7 min of contact. An ord...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(79)90017-3
更新日期:1979-03-01 00:00:00
abstract:INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.08.009
更新日期:2013-02-01 00:00:00
abstract::A fetus with signs of hydrops is at high risk of intrauterine death. The pathophysiology of hydrops fetalis is still unclear. We found decreased concentrations of cyclic guanosine monophosphate in fetal plasma of alloimmunized pregnancies complicated by hydrops fetalis, which might suggest reduced nitric oxide product...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(99)00063-8
更新日期:2000-03-01 00:00:00
abstract::Low birthweight has been associated with diseases and disorders later in life. It has been suggested that this is caused by the impaired development of abdominal organs, especially in cases of growth retardation. Besides general malnutrition of the fetus, preferential bloodflow to the heart and brain may further depri...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00073-x
更新日期:1998-04-17 00:00:00
abstract::Pancreatic protease deficiency may be an aetiological factor in enteritis necroticans, a disease sharing some features of necrotising enterocolitis (NEC). Using faecal chymotrypsin measurement we have prospectively studied pancreatic exocrine function in infants at risk of NEC. No significant difference was found comp...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(93)90100-9
更新日期:1993-12-15 00:00:00
abstract:BACKGROUND:Respiratory syncytial virus (RSV) is a leading cause of hospitalization for children <1year old and is more severe in premature infants. OBJECTIVE:To assess whether late preterm (LPT) birth is an independent risk factor for RSV hospitalization and more severe RSV disease in children less than 24months old. ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.06.009
更新日期:2015-09-01 00:00:00
abstract::During the period 1978-1990 (12.5 years), 929 neonatal general surgical emergencies were treated at the Seoul National University Children's Hospital. There were 308 anorectal malformations, 128 atresia/stenosis of the gut, 125 neonatal Hirschsprung's disease, 75 gastroschisis and 67 esophageal atresias. The highest o...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90194-l
更新日期:1992-06-01 00:00:00
abstract::In this study of 167 neonates who demonstrated a total of 1010 transitions between arousal states, we considered whether specific state transitions were associated with umbilical cord blood lead levels. We found that the arousal patterns of neonates with varying levels (<1, 1-10 and >10 microg/dL) of lead exposure cou...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2007.06.002
更新日期:2008-04-01 00:00:00
abstract::The objective of this work was to examine the changes in the fatty acid profiles of plasma lipid fractions and red blood cell membrane phospholipids in newborn infants during the first 6-8 h of life. Methyl esters of fatty acids from plasma free fatty acids and phospholipids and from membrane phosphatidylethanolamine,...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(87)90041-7
更新日期:1987-03-01 00:00:00
abstract::The aim of this study was to determine whether corticotropin-releasing hormone (CRH) regulates human trophoblast cell growth. The results showed that exogenous CRH significantly stimulated human trophoblast proliferation in first-trimester primary cultures. In vivo, CRH was strongly immunolocalised to cytotrophoblasti...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.04.010
更新日期:2004-08-01 00:00:00
abstract::Placental tissue from five women undergoing elective caesarean did not present differences in fatty acids or mRNA expression of FATP-1, FATP-4 and H-FABP in different placental locations. mRNA expression of FATP-1 and FATP-4 was significantly higher than H-FABP. The expression of L-FABP was too low in placenta for acc...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.02.001
更新日期:2006-10-01 00:00:00
abstract::Slide show presentations have become integral to the workplace, and PowerPoint is ubiquitous since it ships with the Microsoft Office Suite. However, the increasing sophistication of such software may encourage presenters to privilege form over content. It is possible to apply scientific research from Educational Psyc...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.06.006
更新日期:2018-10-01 00:00:00
abstract:AIMS:The aim of the current study was to developed and test the reliability of a technique for measuring temporal parameters of sucking in breastfeeding infants. METHODS:The technique was developed using a cohort of 11 term and 12 preterm infants, and subsequently evaluated using a cohort of 43 preterm infants. Measur...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.04.008
更新日期:2011-08-01 00:00:00
abstract::The purpose of this study was to investigate prostanoid synthesis in different segments of the umbilicoplacental vascular tree and its relationship to impaired maternal glucose tolerance. Segments from the umbilical artery and vein, allantochorionic artery branches, and the cotyledon artery from 21 women with diabetes...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3732(97)00036-2
更新日期:1998-01-09 00:00:00
abstract:BACKGROUND:Children born preterm are at risk of visuospatial attention orienting and processing dysfunctions, which can be quantified early in life using visually-guided eye movement responses. AIMS:To identify the prevalence and perinatal risk factors for visuospatial attention orienting and processing dysfunctions i...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.01.015
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:In previous studies, lower IQ scores and educational difficulties of preterm children were correlated with the reduced size of several brain areas, including the cerebellum and the hippocampus. The most plausible reason for reduction would be the reduced cell formation following premature birth. However, no ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.03.004
更新日期:2004-06-01 00:00:00
abstract::Ninety five placentae from normal term and 'normal' preterm pregnancies have been analysed by morphometry. The growth of the whole placenta, of the microscopic placental constituents and of the villous surface area has been measured in placentae from uncomplicated pregnancies from 10 weeks of gestation to term to prov...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90074-4
更新日期:1984-06-01 00:00:00