Abstract：
AIM:the effect of selective head cooling on cerebral blood flow (CBF) and cerebral metabolism rate (CMR) was investigated in newborn piglets. METHODS:seven days old newborn piglets were randomly assigned to one of the following three groups: Selective head cooling in normal piglets (n=4), selective head cooling after HI (n=6) and normal temperature after HI (n=6). CBF was measured with color microspheres. Cerebral oxygenation metabolism rate (CMRO(2)), Cerebral glucose consumption (CMR(Glu)) and Cerebral lactate production (CMR(lac)) were calculated. RESULT:in normal piglets, CBF, CMRO(2) and CMR(glu) were significantly decreased at both 35°C (P<0.05) and 32°C (P<0.01), while CMR(lac) did not change. Compared to baseline, CBF and CMRO(2) were significantly reduced (P<0.05), while CMR(glu) and CMR(lac) were significantly increased (P<0.01), AVDO(2) was decreased (P<0.05), while AVD(glu) and AVD(lac) were significantly increased (P<0.01 respectively) in HI piglets with normal temperature respectively. Compared to normal temperature after HI, selective head cooling after HI significantly reduced CMR(glu) and CMR(lac), and AVDO(2), AVD(glu), AVD(lac) were improved at 35°C. CONCLUSION:selective head cooling not only reduced energy consumption, but also improve brain oxygen metabolism in newborn after HI.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Cheng G,Sun J,Wang L,Shao X,Zhou Wdoi
10.1016/j.earlhumdev.2010.11.007subject
Has Abstractpub_date
2011-02-01 00:00:00pages
109-14issue
2eissn
0378-3782issn
1872-6232pii
S0378-3782(10)00690-0journal_volume
87pub_type
杂志文章abstract：BACKGROUND:Physical and emotional parent-infant closeness activate important neurobiological mechanisms involved in parenting. In a neonatal care context, most research focuses on physical (parental presence, skin-to-skin contact) aspects; insights into emotional closeness can be masked by findings that overemphasise t...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2020.105155
更新日期：2020-10-01 00:00:00
abstract：OBJECTIVE:To assess patterns of nutritive sucking in very preterm infants ≤32 weeks of gestation. STUDY DESIGN:Very preterm infants who attained independent oral feeding were prospectively assessed with an instrumented feeding bottle that measures nutritive sucking. The primary outcome measure was nutritive sucking pe...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105044
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Children born preterm are known to be at risk for neurodevelopmental disorders. The role of perinatal asphyxia in this increased risk is still a matter of debate. AIM:To analyze the contribution of perinatal asphyxia in a population of preterm infants admitted to a secondary paediatric setting to neurologic...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.06.003
更新日期：2010-07-01 00:00:00
abstract：:In 1% of monozygotic twin pregnancies, one fetus is without a heart; blood circulation is maintained by an accompanying "pump" twin. Such an acardiac condition is usually diagnosed on the basis of further malformations visible by ultrasonography. We describe a monoamniotic twin pregnancy with early growth reduction in...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00011-5
更新日期：1998-08-28 00:00:00
abstract：:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to inv...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90027-g
更新日期：1990-12-01 00:00:00
abstract：:The cephalocaudal progression of jaundice was studied in 136 mature, clinically well newborns. The yellow colour of the skin was measured with the transcutaneous bilirubinometer. Significant positive correlation was found between the yellow colour of the skin in four regions and the plasma bilirubin concentration (for...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90022-b
更新日期：1990-04-01 00:00:00
abstract：:Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70008-8
更新日期：2014-03-01 00:00:00
abstract：:A multicenter randomised trial was conducted in nine neonatal centers in Japan to re-evaluate the safety and the efficacy of high frequency oscillatory ventilation using the piston type oscillator (Hummingbird) in the treatment of respiratory failure in preterm infants weighing between 750 and 2000 g at birth. A total...
journal_title：Early human development
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/0378-3782(93)90088-c
更新日期：1993-02-01 00:00:00
abstract：OBJECTIVE:To evaluate the newborn transient evoked otoacoustic emission (TEOAE) hearing screening tests of infants later diagnosed with the sudden infant death syndrome (SIDS). STUDY DESIGN:In a case-controlled study, the newborn TEOAE hearing screens of 31 infants who subsequently died of SIDS were retrospectively co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.06.001
更新日期：2008-04-01 00:00:00
abstract：:A comparison has been made of protein accretion and growth in premature infants fed banked drip breast milk (BBM) or a preterm formula (PF). Protein accretion was calculated from the difference between dietary nitrogen intake and output in urine and stools, measured in a nutrient balance study. As expected, only the i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90152-5
更新日期：1985-12-01 00:00:00
abstract：:The purpose of this study was to compare two different methods for assessing fetal heart rate (FHR)--fetal eye movement (FEM) synchronization: (1) periods of high (HV) and low (LV) variability in the FHR and the presence (EM) and absence (NEM) of FEM were determined by visual inspection and the degree of association b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90137-6
更新日期：1992-09-01 00:00:00
abstract：:Fetal bladder volume and hourly fetal urine production (HFUPR) is calculated on the assumption that the fetal bladder is ellipsoid in shape. A recent validation study demonstrated a progressive overestimation at increasing bladder volumes. This may be due to changes in shape of the fetal bladder at increasing volumes....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00049-2
更新日期：1998-02-27 00:00:00
abstract：OBJECTIVE:Maternal smoking during pregnancy is associated with a reduction in birth size but very few studies have collated changes in neonatal anthropometry. Our aims were both to assess body composition differences by anthropometry between new-borns from smoking mothers and those from non-smoking mothers, and to show...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.07.015
更新日期：2012-03-01 00:00:00
abstract：:Newborn infants in critical conditions require a permanent intra-venous line to allow for the administration of fluids, parenteral nutrition and drugs. The use of central venous catheters, however, is associated with an increased risk of infections, leading to prolongation of length of stay and higher hospitalization ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70017-9
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:In previous studies, lower IQ scores and educational difficulties of preterm children were correlated with the reduced size of several brain areas, including the cerebellum and the hippocampus. The most plausible reason for reduction would be the reduced cell formation following premature birth. However, no ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.03.004
更新日期：2004-06-01 00:00:00
abstract：:Prevention of extra-uterine growth retardation is of extreme importance, as the achievement of adequate growth has been associated with a favorable neurodevelopmental outcome through childhood. In addition, as disturbances in growth that take place early in life may affect adult health, a full understanding of the gro...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.08.004
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Pregnancy and delivery are complex processes, and isolated obstetric complications rare and often accompanied or followed by a number of others. AIMS:To study the relationship between the overall obstetric situation (as opposed to single obstetric risk factors) and emotional and substance use disorders in y...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.04.016
更新日期：2004-11-01 00:00:00
abstract：:Several studies have described an association between very preterm birth and behavioral and psychiatric outcomes in childhood and adolescence. The exact mechanisms underlying this association are unknown, but impaired neurodevelopment has been proposed as a possible etiological factor. Existing research suggests a sel...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.02.002
更新日期：2013-04-01 00:00:00
abstract：:The mediating effect of maternal self-efficacy in the association between locus of control and anxiety, among mothers of hospitalized babies in the Neonatal Intensive Care Unit (NICU) was examined. Findings confirmed partial mediation effect suggesting that professionals can contribute to the reduction of levels of an...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105284
更新日期：2021-01-01 00:00:00
abstract：:Phosphatidylcholine (PC) is the predominant phospholipid in natural surfactant preparations. A metabolic intermediate, lyso-PC, is potentially injurious to the lungs. In the present study, tracheal aspirates from preterm babies with respiratory distress syndrome treated with surfactant were examined for the presence o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)01885-9
更新日期：1997-09-19 00:00:00
abstract：:The introduction of exchange transfusion made it possible to prevent severe hyperbilirubinemia and kernicterus, but kernicterus has never completely disappeared and it is still occurring in North America and, more frequently in Western Europe and the developing world. I discuss the epidemiology and major causes of sev...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2009.09.003
更新日期：2009-11-01 00:00:00
abstract：:Slide show presentations have become integral to the workplace, and PowerPoint is ubiquitous since it ships with the Microsoft Office Suite. However, the increasing sophistication of such software may encourage presenters to privilege form over content. It is possible to apply scientific research from Educational Psyc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.06.006
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:In the general framework of relating birthing events to later mental development, this study addresses the hypothesis that uneventful non-vertex delivery is associated with higher intelligence than uneventful vertex delivery. STUDY DESIGN:In the course of a developmental obstetrical survey, data was gathered...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90065-5
更新日期：1994-09-30 00:00:00
abstract：AIM:To combine meta-analyses of multiple long-term outcomes in children prenatally exposed to methadone or buprenorphine through their mothers' Opioid maintenance therapy (OMT) with a systematic review of similar outcomes in experimental animals. METHOD:The Medline, Embase, Web of Science, CINAHL, Cochrane and Epistem...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2020.104997
更新日期：2020-04-01 00:00:00
abstract：:Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2008.11.009
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:Tyrosine hydroxylase (TH) is a specific marker for catecholaminergic neurones. Some reports have demonstrated a decrease of TH in the Sudden Infant Death Syndrome (SIDS) compared with controls. To further investigate this, the correlation between TH and sleep apnea was investigated here. MATERIALS AND METHO...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.08.007
更新日期：2003-12-01 00:00:00
abstract：BACKGROUND:A reliable and valid assessing tool to detect the problem before the child becomes deviant is very important. AIM:This study aimed to further test the reliability and validity of developmental screening instrument for follow-up of thirty-six months children in Taiwan. Also, the stability and changes in the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2009.12.004
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Non-nutritive suck (NNS) is one piece of the complex oral feeding process, yet there is paucity on how it develops throughout the first year of life. AIMS:To determine changes in infant NNS between 3 and 12 months of age. STUDY DESIGN:Twenty-six full-term infants (65% male) completed this study. All infant...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105141
更新日期：2020-10-01 00:00:00
abstract：:Cardiovascular malformations are frequently associated in patients with esophageal atresia (EA). We observed azygos continuation mimicking an aortic arch anomaly in four newborns with type III EA. They presented concomitant rib anomalies indicating a common developmental defect. Foreknowledge is important for planning...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.05.007
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:There have been few research studies aimed at obtaining a better understanding of the prediction of subsequent respiratory morbidity at follow-up in infants with a previous history of bronchopulmonary dysplasia (BPD) living in low- and middle-income countries (LMIC). The aim of the present study was to ident...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.10.003
更新日期：2018-12-01 00:00:00
