Abstract：
:The introduction of exchange transfusion made it possible to prevent severe hyperbilirubinemia and kernicterus, but kernicterus has never completely disappeared and it is still occurring in North America and, more frequently in Western Europe and the developing world. I discuss the epidemiology and major causes of severe hyperbilirubinemia and the potential root causes and system failures associated with the development of extreme hyperbilirubinemia and, subsequently, kernicterus. In the Western world, kernicterus remains a rare cause of cerebral palsy but, in contrast to the other causes of cerebral palsy, kernicterus should almost always be preventable. The key elements in preventing kernicterus are risk assessment and appropriate follow-up for the newborn infant and these are presented in a recently developed algorithm. Implementation of this approach might contribute to the prevention of severe hyperbilirubinemia and bilirubin encephalopathy.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Maisels MJdoi
10.1016/j.earlhumdev.2009.09.003subject
Has Abstractpub_date
2009-11-01 00:00:00pages
727-32issue
11eissn
0378-3782issn
1872-6232pii
S0378-3782(09)00191-1journal_volume
85pub_type
杂志文章,评审abstract：:Cardiovascular malformations are frequently associated in patients with esophageal atresia (EA). We observed azygos continuation mimicking an aortic arch anomaly in four newborns with type III EA. They presented concomitant rib anomalies indicating a common developmental defect. Foreknowledge is important for planning...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.05.007
更新日期：2017-08-01 00:00:00
abstract：:The brain glycoconjugates, glycosidases and lipids have been studied in a case of human congenital athyroidism never treated with hormonal replacement. Increase of membrane-bound mucopolysaccharides has been found in the grey matter. Total lipids in the white matter, and phospholipids, and total glycolipids and choles...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90009-9
更新日期：1983-10-01 00:00:00
abstract：BACKGROUND:Preterm children are at risk for executive function (EF) problems, which have been linked to behavior and learning problems in full term children. In this study, we examine the relationship between EF and functional outcomes in preterm children. AIM:To evaluate (1) EF skills of 9- to 16-year-old children bo...
journal_title：Early human development
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2011.07.018
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Preterm newborns have low vitamin A reserves at birth, which increases their risk of morbidity and mortality. In the absence of supplementation, breast milk is the only source of this nutrient for exclusively breastfed infants. AIMS:To assess retinol concentration in preterm milk and the relationship betwee...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.01.006
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Placental pathology is associated with long-term neurological morbidity. Little is known about the association of placental pathology and illness severity directly after birth in preterm infants. OBJECTIVE:To determine the association between placental pathology and illness severity in preterm infants durin...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.01.040
更新日期：2011-04-01 00:00:00
abstract：:Interfacility transport to tertiary care for high-risk neonates has become an integral part of equitable access to optimal perinatal healthcare. Excellence in clinical care requires expertise in transport medicine and the coordination of safe transport processes. However, concerns remain regarding environmental stress...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2020.105051
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Maternal pre-pregnancy overweight is known to program offspring for adverse health outcomes later in life. AIMS:To investigate how growth patterns of weight, height and BMI from birth to 7years differ according to maternal pre-pregnancy weight (normal weight, overweight and obesity), with specific attention...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.06.002
更新日期：2017-10-01 00:00:00
abstract：:The aim is to know whether antenatal olfactory learning have a greater effect than postnatal olfactory learning on infant feeding even in the absence of triggering signals. We evaluated the sucking behavior of infants completely separated from their mothers for 10-14 days since birth. The 12 infants admitted to Chiba ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.10.003
更新日期：2004-02-01 00:00:00
abstract：:Serum albumin levels decrease during pregnancy while the concentration of most other maternal serum proteins of hepatic origin remain stable or increase. In a study of 289 women, most maternal characteristics such as race, age, smoking, a history of previous low birth-weight, infant sex and gestational age at delivery...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(93)90178-w
更新日期：1993-10-01 00:00:00
abstract：:Doctors are frequently depicted as important protagonists in science fiction, including in the science fiction franchise Star Trek. This paper will profile Drs. Philip Boyce and Mark Piper from the first two Star Trek pilot episodes. These doctors are interdisciplinarians with a variety of skills that permit them to c...
journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2020.104988
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Fetal cells exfoliate in the uterine cavity during early pregnancy and are a potential source of material for NIPD. AIMS:This study was designed to test the hypothesis that fetal cells obtained from the uterine cervix during the first trimester of pregnancy could be utilized for prenatal diagnosis of chromo...
journal_title：Early human development
pub_type： 临床试验,杂志文章
doi：10.1016/j.earlhumdev.2010.04.005
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:Extremely-low-birth-weight (ELBW) children without severe brain injury or CP are at high risk of developing deficits within cognition, attention, behavior and motor function. Assessing the quality of an infant's spontaneous motor-repertoire included in Prechtl's General-Movement-Assessment (GMA) has been sho...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.07.005
更新日期：2014-10-01 00:00:00
abstract：INTRODUCTION:The 2D:4D digit ratio is sexually-dimorphic, probably due to testosterone action through the perinatal period. We characterize the 2D:4D ratio in newborn (NB) infants, in between the pre- and postnatal surges of testosterone, and relate it to the mother's 2D:4D and to testosterone levels in the amniotic fl...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.08.009
更新日期：2013-02-01 00:00:00
abstract：:Measurement of methionine levels in dried blood spots has been one of the items of neonatal screening in Taiwan for more than 20 years. In 1,701,591 newborns, 17 cases of hypermethioninemia were detected, but among them only one had homocystinuria. More than half of the 16 cases of isolated hypermethioninemia had muta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.11.005
更新日期：2005-06-01 00:00:00
abstract：:The magnitude of inflating pressure necessary for effective resuscitation was examined in 70 preterm infants. The median pressure to cause adequate chest wall expansion was 22.8 cmH2O; no infant required a peak inflating pressure greater than 30 cmH2O. No further increase in inflation pressure was used during resuscit...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90045-5
更新日期：1991-07-01 00:00:00
abstract：INTRODUCTION:Survivors of congenital diaphragmatic hernia have increased with the introduction of new treatment modalities and have been reported to experience ongoing medical morbidity until adulthood. AIM:To describe the long-term functional impact of congenital diaphragmatic repair on the survivors of a single inst...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.08.025
更新日期：2012-04-01 00:00:00
abstract：:Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2008.11.009
更新日期：2009-02-01 00:00:00
abstract：BACKGROUND:The kidney is one organ which presents distinct morphology depending on GA; the classic references for kidney measurements were established several years ago and it is not certain if they are still accurate. AIM:To evaluate the renal maturity using a computer-assisted morphometry in autopsied fetuses within...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.01.013
更新日期：2006-11-01 00:00:00
abstract：:A significant improvement has been achieved in perinatal mortality figures during the last decade in Japan with a neonatal mortality rate of 2.6 and a stillbirth rate of 4.1 for 1989. With its unique obstetric and neonatal services, there are advantages and also disadvantages in respect of clinical and basic research....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90185-j
更新日期：1992-06-01 00:00:00
abstract：:No statistically significant relationships were observed between the red blood cell acid phosphatase polymorphism (ACP-1) and birth weight, duration of gestation and proportion of preterm infants in a large series of newborn infants (greater than 8000) in Cardiff. These results are contrasted with those of a similar, ...
journal_title：Early human development
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:Low nephron endowment secondary to intrauterine growth restriction (IUGR) results in compensatory hypertrophy of the remaining glomeruli, which in turn is associated with hypertension. However, gender differences exist in the response of the kidney to injury, and IUGR female offspring seems protected from an unfavorab...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.12.015
更新日期：2009-06-01 00:00:00
abstract：:The relationship between maternal menstrual history and small-for-gestational-age (SGA) births is examined in a population-based birth cohort of 5291 mothers with singleton births and 28 completed gestational weeks in Qingdao, China, in 1992. Multivariate analyses suggest that the length of the menstrual cycle and age...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00031-5
更新日期：1997-10-10 00:00:00
abstract：:Whenever possible, oral feeding is the preferred method in neonatal feeding. However, many premature infants are unable to suck and swallow effectively; in these cases alternative methods of nutrient delivery must be used. We briefly review the different feeding methods used in neonatal units, with particular attentio...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(12)70011-7
更新日期：2012-05-01 00:00:00
abstract：:Case-control studies are frequently performed in prenatal and perinatal epidemiology. For data collection, these studies often rely on self-administered questionnaires or personal interviews. Although of importance, validation of these measurement instruments received little attention in epidemiologic research so far....
journal_title：Early human development
pub_type： 评论,信件
doi：10.1016/j.earlhumdev.2010.09.372
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Testosterone (T) is taken or prescribed to enhance appearance, increase athletic performance and libido and to treat hypogonadism. Digit ratio (2D:4D) is thought to be a negative correlate of prenatal T. Here we consider the relationship between 2D:4D and T supplementation. AIMS:Our sample was taken from th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.104843
更新日期：2019-12-01 00:00:00
abstract：AIM:This study examined the rates of follow-up for a cohort of extremely preterm (EP -<28weeks gestation) and/or extremely low birthweight (ELBW -<1000g) children at two years with related perinatal and geographical factors. The secondary aim was to determine the rates of developmental delay and disability. METHODS:A ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.09.012
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Non-nutritive suck (NNS) is one piece of the complex oral feeding process, yet there is paucity on how it develops throughout the first year of life. AIMS:To determine changes in infant NNS between 3 and 12 months of age. STUDY DESIGN:Twenty-six full-term infants (65% male) completed this study. All infant...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105141
更新日期：2020-10-01 00:00:00
abstract：:Candidal chorioamnionitis is an uncommon and apparently rather indolent intrauterine infection in which the fetus is able to marshal some of the immunological forces at its disposal against an easily visualized antigen impinging on lung mucosal surfaces. In a retrospective histological study of one of the largest repo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90113-6
更新日期：1985-05-01 00:00:00
abstract：BACKGROUND:An increased risk of major congenital abnormalities after IVF and ICSI has been described, but underlying mechanisms are unclear. This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.06.002
更新日期：2012-10-01 00:00:00
abstract：:Data on the postnatal growth patterns of 238 small-for-gestational age (SGA) and 241 large-for-gestational age (LGA) babies are presented. Three proportionality ratios were selected; and their changes in shape, by these indices, during the first 7 years are compared with a random sample of 284 children drawn from the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90095-2
更新日期：1986-02-01 00:00:00
