Abstract：
BACKGROUND:Pregnancy and delivery are complex processes, and isolated obstetric complications rare and often accompanied or followed by a number of others. AIMS:To study the relationship between the overall obstetric situation (as opposed to single obstetric risk factors) and emotional and substance use disorders in young adulthood, and to analyse whether these links are mediated by temperaments in childhood. STUDY DESIGN:In a prospective birth cohort (n=3162), questionnaires were sent to mothers and teachers when the child was 7-10 years old, and to the children when they were 20-25 years old. SUBJECTS:Six hundred and eighty-two cohort members with complete data sets at three ages (perinatal, childhood, and young adulthood). OUTCOME MEASURES:Emotional problems and substance use in young adulthood. MAIN RESULTS:Substance use in young adulthood was predicted better by the overall obstetrical optimality score than emotional problems were. Links studied were stronger for men than for women. CONCLUSIONS:This study demonstrated the use of an aggregated obstetrical optimality score in analysing the associations between early risk factors and emotional problems and substance use in young adulthood.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Batstra L,Hadders-Algra M,Ormel J,Neeleman Jdoi
10.1016/j.earlhumdev.2004.04.016keywords:
subject
Has Abstractpub_date
2004-11-01 00:00:00pages
91-101issue
2eissn
0378-3782issn
1872-6232pii
S0378-3782(04)00083-0journal_volume
80pub_type
杂志文章abstract：:This year is the 20th anniversary of the first successful trial of exogenous surfactant for respiratory distress syndrome in the newborn and it is perhaps a good time to review recent advances in basic science and clinical practice as they relate to surfactant therapy. ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(00)00122-5
更新日期：2001-03-01 00:00:00
abstract：BACKGROUND:Septic complications lead to a high mortality rate in very low birthweight infants (VLBWI). Therefore, prognostic markers for the development of sepsis attach importance to start an efficient therapy as early as possible. AIMS:Functional and phenotypical variables of blood monocytes in the cord and peripher...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00245-6
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journal_title：Early human development
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journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90142-2
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journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/s0378-3782(99)00021-3
更新日期：1999-06-01 00:00:00
abstract：:A significant improvement has been achieved in perinatal mortality figures during the last decade in Japan with a neonatal mortality rate of 2.6 and a stillbirth rate of 4.1 for 1989. With its unique obstetric and neonatal services, there are advantages and also disadvantages in respect of clinical and basic research....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90185-j
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.08.017
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journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：2001-12-01 00:00:00
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journal_title：Early human development
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：2014-10-01 00:00:00
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journal_title：Early human development
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更新日期：2020-10-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：1978-04-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.09.002
更新日期：2003-12-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,实务指引
doi：10.1016/j.earlhumdev.2020.104988
更新日期：2020-05-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2007.08.002
更新日期：2007-11-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(02)00075-0
更新日期：2002-12-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：2009-06-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章,评审
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.03.009
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journal_title：Early human development
pub_type： 杂志文章,meta分析
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更新日期：2016-12-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2014.08.022
更新日期：2014-11-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.01.010
更新日期：2006-10-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章,实务指引
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更新日期：2020-01-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.11.001
更新日期：2011-02-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：2001-11-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
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更新日期：1983-12-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105117
更新日期：2020-09-01 00:00:00
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journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.01.012
更新日期：2012-08-01 00:00:00
