Abstract：
AIM:The benefit of anti-reflux surgery for gastro-oesophageal reflux (GOR) in early infancy is uncertain. The aim of this study was to assess the value of Nissen fundoplication in a group of infants with severe GOR. METHODS:10 infants underwent Nissen fundoplication for gastro-oesophageal reflux following a failure of medical management. All had suffered life-threatening respiratory episodes as a consequence of gastro-oesophageal reflux, and were neonatal intensive care-dependent. Median (range) birth weight was 1.26 kg (0.48-3.8 kg), gestation 30 weeks (25-38 weeks); at surgery, weight was 3.25 kg (2.5-6.1 kg) at a corrected age of 11.5 weeks (term-22) weeks. For each infant, the success of enteral feeding and the level of support required pre- and post-operatively was compared, and where appropriate, the facilitation of palliative feeding was assessed. Median follow-up was 14 (3-36) months. RESULTS:No infant suffered intra-operative morbidity or mortality. One infant died within 1 month of surgery from a collapse unrelated to surgery. Eight of nine surviving infants were discharged from intensive care following extubation and the establishment of enteral feeding. One patient died of severe bronchopulmonary dysplasia 3 months post-surgery. One infant developed a gastrostomy site infection, and two required gastrostomy tube replacement within 6 months of surgery. All were thriving at follow-up. Two infants with a congenital myopathy died as a result of their muscle disease at 9 and 11 months post-operatively. CONCLUSIONS:Nissen fundoplication is a feasible, effective and safe operation in severe gastro-oesophageal reflux unresponsive to medical treatment in term and pre-term infants. It has an additional important role in facilitating safe palliative enteral feeding in infants with a diagnosis incompatible with survival into adulthood.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Barnes N,Robertson N,Lakhoo Kdoi
10.1016/j.earlhumdev.2003.09.002keywords:
subject
Has Abstractpub_date
2003-12-01 00:00:00pages
71-8issue
1-2eissn
0378-3782issn
1872-6232pii
S0378378203001488journal_volume
75pub_type
杂志文章abstract：:The cephalocaudal progression of jaundice was studied in 136 mature, clinically well newborns. The yellow colour of the skin was measured with the transcutaneous bilirubinometer. Significant positive correlation was found between the yellow colour of the skin in four regions and the plasma bilirubin concentration (for...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90022-b
更新日期：1990-04-01 00:00:00
abstract：OBJECTIVE:To 1) define predictors of parent presence, any holding, holding in arms, and skin-to-skin care in the NICU and 2) investigate the relationships between parent participation and a) early neurobehavior and b) developmental outcomes at age 4 to 5years among preterm infants. METHODS:Eighty-one preterm infants b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.12.008
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Birthweight is an important predictor of various fundamental aspects of childhood health and development. AIM:To examine the impact of birthweight on childhood balance performance classification and verify if this is replicable and consistent in different populations. STUDY DESIGN:Prospective birth cohort ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.01.010
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:Many preterm children show difficulties in attention at (pre)school age. The development of attention capacities of preterm and term toddlers was compared using a longitudinal and multi-method approach at 12, 18 and 24months. METHOD:Attention was measured for 123 preterm (32-36weeks gestation) and 101 term b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.08.015
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. AIMS:To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. STUDY DESIGN:Retrospective cohort stu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.03.006
更新日期：2015-05-01 00:00:00
abstract：:The calculation of descriptive statistics includes the calculation of standard error and confidence interval, an inevitable component of data analysis in inferential statistics. This paper provides pointers as to how to do this in Microsoft Excel™. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.01.013
更新日期：2018-03-01 00:00:00
abstract：AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00256-0
更新日期：2002-04-01 00:00:00
abstract：:Index and regression methods of selecting babies whose heads are out of proportion to their body weight are examined and compared. The ratios head circumference3/birthweight and head circumference3/birthweightP (where P is a power found by regression methods) are used, and the regression of head circumference 3 on bir...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(80)90039-0
更新日期：1980-12-01 00:00:00
abstract：AIMS:To determine the reproducibility and minimum detectable change (MDC) of heart rate variability (HRV) measures during two sequential 24-h periods, at week 32 of gestation, in preterm infants born between 28 and 32 weeks, hospitalized in the neonatal intensive care unit (NICU). The second aim is to assess postnatal ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105117
更新日期：2020-09-01 00:00:00
abstract：:The relationship between blood glucose and body physique of 233 (42 hypo-and 191 normologycemic) intrauterine growth-retarded neonates was analyzed using different body measurements and indices of body proportions. Classification by combination of weight and length deficit for fetal age revealed that the disproportion...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90027-5
更新日期：1977-10-01 00:00:00
abstract：:Case-control studies are frequently performed in prenatal and perinatal epidemiology. For data collection, these studies often rely on self-administered questionnaires or personal interviews. Although of importance, validation of these measurement instruments received little attention in epidemiologic research so far....
journal_title：Early human development
pub_type： 评论,信件
doi：10.1016/j.earlhumdev.2010.09.372
更新日期：2011-01-01 00:00:00
abstract：:In planning enteral feeding in the preterm infant, decisions need to be made regarding the feeding schedule, choice of milk, and the route of administration. Feeds should be commenced within a week after birth beginning with subnutritional quantities. Preterm human milk from the infant's own mother is the milk of choi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(99)00047-x
更新日期：1999-12-01 00:00:00
abstract：:The world's literature has been scoured to obtain data on 492 examples of the fetal alcohol syndrome (FAS) in the Northern Hemisphere. The seasonally pattern of FAS birth prevalence rates is compared with the seasonality pattern of ethanol intakes to estimate the time-lag between them and hence the timing of ethanol d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90065-8
更新日期：1983-07-01 00:00:00
abstract：:COVID-19 remains pandemic. Social distancing and travel restrictions have avoided countless deaths and infections but disrupted livelihoods and economies. The global loss of gross (world) product is unprecedented as COVID-19 has inflicted both a supply-side and a demand-side shock. While public health measures have mi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105209
更新日期：2020-10-01 00:00:00
abstract：:Human and animal studies demonstrate that uteroplacental insufficiency and subsequent intrauterine growth retardation (IUGR) decrease intestinal growth and lead to both an increased incidence of feeding intolerance and necrotizing enterocolitis. Our objective was to determine the effects of uteroplacental insufficienc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.04.015
更新日期：2004-09-01 00:00:00
abstract：:Among 7 subjects with hyperemesis gravidarum (HG), we found gabapentin therapy to be associated with mean reductions in nausea and emesis from Baseline to Days 12-14 of 80% and 94%, respectively. There have been 2 congenital defects among 7 exposed infants. Gabapentin may be effective in the treatment of HG. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2009.11.003
更新日期：2010-01-01 00:00:00
abstract：AIM:Depression during pregnancy is a significant cause of adverse birth outcomes, and its prevalence has increased in recent years. This study aimed to give an updated quantification of the risk of preterm birth (PTB), low birth weight (LBW) and intrauterine growth restriction (IUGR) that is associated with antenatal d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105243
更新日期：2021-01-01 00:00:00
abstract：:A multicenter randomised trial was conducted in nine neonatal centers in Japan to re-evaluate the safety and the efficacy of high frequency oscillatory ventilation using the piston type oscillator (Hummingbird) in the treatment of respiratory failure in preterm infants weighing between 750 and 2000 g at birth. A total...
journal_title：Early human development
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/0378-3782(93)90088-c
更新日期：1993-02-01 00:00:00
abstract：BACKGROUND:Controversy exists regarding association of high levels of proinflammatory cytokines, neonatal morbidities and poor neurodevelopment outcome in very low birth weight infants. OBJECTIVE:To determine association between severity of early inflammatory response and neurodevelopment outcome in high risk very low...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.03.009
更新日期：2011-06-01 00:00:00
abstract：:This study examined the oral sensitivity and feeding skills of low-risk pre-term infants at 11-17 months corrected age. Twenty pre-term infants (PT) born between 32 and 37 weeks at birth without any medical comorbidities were assessed. All of this PT group received supplemental nasogastric (NG) tube feeds during their...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.10.001
更新日期：2004-01-01 00:00:00
abstract：OBJECTIVE:Maternal smoking during pregnancy is associated with a reduction in birth size but very few studies have collated changes in neonatal anthropometry. Our aims were both to assess body composition differences by anthropometry between new-borns from smoking mothers and those from non-smoking mothers, and to show...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.07.015
更新日期：2012-03-01 00:00:00
abstract：:Newborn infants in critical conditions require a permanent intra-venous line to allow for the administration of fluids, parenteral nutrition and drugs. The use of central venous catheters, however, is associated with an increased risk of infections, leading to prolongation of length of stay and higher hospitalization ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70017-9
更新日期：2014-03-01 00:00:00
abstract：:Eleven healthy, full-term babies were studied on the second day (d2) after birth and again 4 weeks (w4) later. The babies lived in natural lighting conditions and were fed every 4 h. Blood pressure, heart rate, skin (abdomen) and rectal temperatures were measured at 10-min intervals for 24 h. Behavioural states (deep ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90039-6
更新日期：1994-02-01 00:00:00
abstract：:Discrepancies between active and passive muscle power are often seen in pre-term infants over the first year. Generally of a transient nature, they are most obvious in the extensor muscles of the trunk where there is a high active muscle power relative to the passive component. While high active muscle power may not b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01661-l
更新日期：1995-08-30 00:00:00
abstract：:Bronchopulmonary dysplasia (BPD) is one of the most important sequelae of premature birth and the most common form of chronic lung disease of infancy. From a clinical standpoint BPD subjects are characterized by recurrent respiratory symptoms, which are very frequent during the first years of life and, although becomi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.07.015
更新日期：2013-10-01 00:00:00
abstract：:The calculation of descriptive statistics after data collection provides researchers with an overview of the shape and nature of their datasets, along with basic descriptors, and may help identify true or incorrect outlier values. This exercise should always precede inferential statistics, when possible. This paper pr...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.02.015
更新日期：2018-03-01 00:00:00
abstract：INTRODUCTION:Reduced left ventricular (LV) diastolic function can exert significant load to the right ventricle (RV) that can affect RV-pulmonary vasculature (PV) coupling. RV-PV can be assessed with the RV length-force relationship (tricuspid annular plane systolic excursion [TAPSE] to pulmonary artery acceleration ti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.11.006
更新日期：2019-01-01 00:00:00
abstract：:The brain glycoconjugates, glycosidases and lipids have been studied in a case of human congenital athyroidism never treated with hormonal replacement. Increase of membrane-bound mucopolysaccharides has been found in the grey matter. Total lipids in the white matter, and phospholipids, and total glycolipids and choles...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90009-9
更新日期：1983-10-01 00:00:00
abstract：:Fungal-related morbidity and mortality is a major concern for most neonatal intensive care units (NICUs) worldwide. Incidence rates are increasing and might be higher than reported due to the challenges associated with diagnosing fungal infections. As preterm neonates display clinical characteristics that make them pr...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2011.01.013
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:Infants whose mothers had low serum pregnancy-associated plasma protein-A (PAPP-A) in the first trimester were observed to have intrauterine growth retardation. AIM:Suggesting that PAPP-A plays an important role in the availability and activity of insulin-like growth factors (IGFs), which affect growth, we ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.10.005
更新日期：2007-07-01 00:00:00
