Abstract：
:Fungal-related morbidity and mortality is a major concern for most neonatal intensive care units (NICUs) worldwide. Incidence rates are increasing and might be higher than reported due to the challenges associated with diagnosing fungal infections. As preterm neonates display clinical characteristics that make them prone to Candida spp infections, and there is a high frequency of severe neurodevelopmental sequelae in those who survive neonatal fungal infections, specific prevention--rather than empiric or pre-emptive treatment--should be the optimal strategy. Besides stewardship of drug use and efforts to minimize invasive cares, pharmacological prevention with use of fluconazole has proved highly effective in decreasing the rates of fungal sepsis in very low birth weight (VLBW) neonates. Alternative options needing further and more conclusive assessments include use of nystatin, bovine lactoferrin or probiotics.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Manzoni P,Jacqz-Aigrain E,Rizzollo S,Franco C,Stronati M,Mostert M,Farina Ddoi
10.1016/j.earlhumdev.2011.01.013subject
Has Abstractpub_date
2011-03-01 00:00:00pages
S59-60eissn
0378-3782issn
1872-6232pii
S0378-3782(11)00023-5journal_volume
87 Suppl 1pub_type
杂志文章,评审abstract：BACKGROUND:Infants whose mothers had low serum pregnancy-associated plasma protein-A (PAPP-A) in the first trimester were observed to have intrauterine growth retardation. AIM:Suggesting that PAPP-A plays an important role in the availability and activity of insulin-like growth factors (IGFs), which affect growth, we ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.10.005
更新日期：2007-07-01 00:00:00
abstract：BACKGROUND:Studies on motor performance and its early markers are rare in China, especially in very low birth weight (VLBW) infants. OBJECTIVE:Apart from the assessment of the inter-scorer agreement, we aimed to analyze to what extent the motor repertoire at 10 to 18weeks postterm was related to neonatal complications...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.03.010
更新日期：2016-09-01 00:00:00
abstract：BACKGROUND:The long-term effect of early intervention in infants at risk for developmental disorders is unclear. The VIP project (n=46, originally) evaluated by means of a randomised controlled trial the effect of the family centred early intervention programme COPCA (Coping with and Caring for infants with special nee...
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2017.02.002
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Angiogenesis, a critical process for growth and development is altered in intrauterine growth restriction (IUGR). Vascular endothelial growth factor (VEGF) and its receptors VEGFR-1, soluble (s) VEGFR-1 and VEGFR-2 represent a regulatory system, essential for both physiological and pathological angiogenesis....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2005.09.010
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.006
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Routine oropharyngeal suctioning in term vigorous neonates immediately after birth is a questionable practice. Current recommendations favor suctioning only in the presence of considerable obstruction due to secretions, blood or other matter. We aimed to analyze the influence of oropharyngeal suctioning on c...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.01.005
更新日期：2015-02-01 00:00:00
abstract：:This paper describes the use of automated microscopy to detect fetal erythroblasts in maternal blood. The technology is based on the following approach: (1) the use of centrifugal cytology for the preparation of monolayers; (2) simultaneous staining of fetal hemoglobin (immunoalkaline phosphatase) and chromosome seque...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01829-4
更新日期：1996-12-30 00:00:00
abstract：:Prevention of extra-uterine growth retardation is of extreme importance, as the achievement of adequate growth has been associated with a favorable neurodevelopmental outcome through childhood. In addition, as disturbances in growth that take place early in life may affect adult health, a full understanding of the gro...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.08.004
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Even though the biological norm in humans is frequent on demand breastfeeding, sparse feeding intervals have become the cultural norm in most Western countries due to a history of on schedule breastfeeding. This discrepancy between the biological basis and the culturally driven practice continues to interfer...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105242
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Patent ductus arteriosus (PDA) is common in extremely premature infants and associated with increased morbidity and mortality. Medical management of PDA uses either indomethacin or ibuprofen. Despite numerous studies, uncertainty exists as to which drug is safer or more effective; we sought to fill this know...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.08.003
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Preterm children are at risk for executive function (EF) problems, which have been linked to behavior and learning problems in full term children. In this study, we examine the relationship between EF and functional outcomes in preterm children. AIM:To evaluate (1) EF skills of 9- to 16-year-old children bo...
journal_title：Early human development
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2011.07.018
更新日期：2012-02-01 00:00:00
abstract：:To learn if chemoreceptor control of breathing is abnormal in babies whose mothers took narcotics, cocaine, or both drugs during pregnancy, we performed hypoxia and hypercapnia challenges on 28 babies (greater than or equal to 36 weeks gestation). Six babies were exposed to narcotics, six to cocaine, nine to both drug...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90193-7
更新日期：1991-12-01 00:00:00
abstract：BACKGROUND:The entorhinal cortex serves as an important gateway between the cerebral cortex and the hippocampus by receiving afferent information from limbic, modality sensory-specific, and multimodal association fibers from all the brain lobes. AIM:To investigate whether thinning of entorhinal cortex is associated wi...
journal_title：Early human development
pub_type： 临床试验,杂志文章
doi：10.1016/j.earlhumdev.2011.07.017
更新日期：2012-02-01 00:00:00
abstract：:Slide show presentations have become integral to the workplace, and PowerPoint is ubiquitous since it ships with the Microsoft Office Suite. However, the increasing sophistication of such software may encourage presenters to privilege form over content. It is possible to apply scientific research from Educational Psyc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.06.006
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Despite its prevalence and potential maternal and neonatal implications, the literature on the thickness levels of meconium stained amniotic fluid (MSAF) and its impact on neonatal outcomes is relatively outdated and relies on relatively small sample sizes. AIMS:To study if different thickness levels of MSA...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.104953
更新日期：2020-03-01 00:00:00
abstract：:A comparison has been made of protein accretion and growth in premature infants fed banked drip breast milk (BBM) or a preterm formula (PF). Protein accretion was calculated from the difference between dietary nitrogen intake and output in urine and stools, measured in a nutrient balance study. As expected, only the i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90152-5
更新日期：1985-12-01 00:00:00
abstract：:Son preference remains common in countries from East Asia through South Asia to the Middle East and North Africa. Where sex selective technology and abortion are readily available, such as in China, South Korea and India, this has led to a marked excess in male births. Worst excesses are seen in parts of rural China w...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.08.016
更新日期：2011-11-01 00:00:00
abstract：:In 1% of monozygotic twin pregnancies, one fetus is without a heart; blood circulation is maintained by an accompanying "pump" twin. Such an acardiac condition is usually diagnosed on the basis of further malformations visible by ultrasonography. We describe a monoamniotic twin pregnancy with early growth reduction in...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00011-5
更新日期：1998-08-28 00:00:00
abstract：:Atrial natriuretic factor (ANF) has been well known as a potent natriuretic peptide. The purpose of this study was to clarify the physiological role of ANF in neonates. We designed two types of study to investigate the role of ANF in neonates. (i) The role of ANF in neonatal fluid homeostasis; (ii) ANF and spontaneous...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90132-z
更新日期：1992-06-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：:The influence of lung function and reflex activity on the success of patient-triggered ventilation (PTV) has been determined. Lung function was assessed by measurement of compliance using a single breath technique. Reflex activity was assessed by measurement of the strength of Hering Breuer reflex indicated by the deg...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90142-2
更新日期：1994-04-30 00:00:00
abstract：:Interest in determining the quality of life of children and adults is now considered a priority. This is a result of a shift in thinking with greater transparency in finding out not only the health outcomes, but also the personal burden of illness and life satisfaction for the individual. However, there is still no co...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.01.012
更新日期：2013-04-01 00:00:00
abstract：:Bilirubin-albumin binding was quantitated (peroxidase method) before, during, and after phototherapy in 21 jaundiced infants. Binding was analyzed at two different serum dilutions (1:1.8 and 1:57) to determine whether binding competitors are present during phototherapy. No significant changes in binding were found at ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90099-8
更新日期：1982-04-01 00:00:00
abstract：:Data on the postnatal growth patterns of 238 small-for-gestational age (SGA) and 241 large-for-gestational age (LGA) babies are presented. Three proportionality ratios were selected; and their changes in shape, by these indices, during the first 7 years are compared with a random sample of 284 children drawn from the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90095-2
更新日期：1986-02-01 00:00:00
abstract：AIMS:To study longitudinal growth pattern of head circumference of full-term symmetric and asymmetric small for gestational age (SGA) infants of the two sexes during first year of life. STUDY DESIGN:Mixed-longitudinal growth research design. SUBJECTS:Head circumference amongst full-term 100 symmetric, 100 asymmetric ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.11.007
更新日期：2012-07-01 00:00:00
abstract：:A fetus with signs of hydrops is at high risk of intrauterine death. The pathophysiology of hydrops fetalis is still unclear. We found decreased concentrations of cyclic guanosine monophosphate in fetal plasma of alloimmunized pregnancies complicated by hydrops fetalis, which might suggest reduced nitric oxide product...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00063-8
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. AIMS:To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. STUDY DESIGN:Retrospective cohort stu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.03.006
更新日期：2015-05-01 00:00:00
abstract：:Twenty-four term infants with disproportionate intrauterine growth retardation (SGA group) and 24 normally grown term infants matched for age, sex, birth rank and social class were followed from birth until 7 years of age. Both groups were free from perinatal complications and chronic diseases. The children in the SGA...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90038-2
更新日期：1988-11-01 00:00:00
abstract：BACKGROUND:Preterm infants have immature skin, which contributes to skin problems. Very little is known about postnatal changes in the skin, despite the clinical importance of this issue. AIM:To assess temporal changes in skin water content in preterm infants. STUDY DESIGN:A prospective observational study. SUBJECTS...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.05.009
更新日期：2015-09-01 00:00:00
abstract：:In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90140-e
更新日期：1990-11-01 00:00:00
