Abstract：
:The cephalocaudal progression of jaundice was studied in 136 mature, clinically well newborns. The yellow colour of the skin was measured with the transcutaneous bilirubinometer. Significant positive correlation was found between the yellow colour of the skin in four regions and the plasma bilirubin concentration (forehead: rho = 0.83, abdomen: rho = 0.89, knee: rho = 0.82, and foot: rho = 0.65, all P less than 0.00001). The values obtained from the forehead were significantly higher than the values obtained from the abdomen (P less than 0.0001), the knee (P less than 0.00001), and the foot (P less than 0.00001). The cephalocaudal progression of jaundice correlated positively with the plasma bilirubin concentration (rho = 0.58, P less than 0.00001) and inversely with the gestational age (rho = -0.28, P less than 0.01). The results support a proposed hypothesis explaining the cephalocaudal progression of jaundice in newborns. According to the hypothesis, the cephalocaudal colour difference may be caused by the presence of young bilirubin-albumin complexes in the blood undergoing conformational changes.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Knudsen Adoi
10.1016/0378-3782(90)90022-bsubject
Has Abstractpub_date
1990-04-01 00:00:00pages
23-8issue
1eissn
0378-3782issn
1872-6232pii
0378-3782(90)90022-Bjournal_volume
22pub_type
杂志文章abstract：BACKGROUND:Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM:To estimate the risk of attention problems at age 10years in children born very preterm to overweight ...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2017.08.002
更新日期：2017-12-01 00:00:00
abstract：:Oesophageal pressure and ventilation were recorded during sleep in healthy full-term neonates with sleep state defined by one of two methods; in 35 infants by combined behavioural and electroencephalographic criteria, and in a further 13 infants by behavioural criteria alone. Spontaneous oesophageal contractions occur...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90054-0
更新日期：1988-12-01 00:00:00
abstract：INTRODUCTION:Little is known about sex differences in human fetal heart and behaviour. PATIENTS AND METHODS:One hundred twenty-three nulliparous healthy women carrying a male (n=56) or female (n=67) fetus participated in this study. All pregnancies remained uncomplicated and delivery was uneventful. Ultrasound observa...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(03)00047-1
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Although highly beneficial, human milk feeding is challenging in preterm infants due to adverse NICU factors for the infant and mother. AIM:To investigate the effects of an early intervention in promoting infant's human milk feeding and acquisition of full oral feeding. METHODS:This study is part of a RCT....
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2018.04.016
更新日期：2018-06-01 00:00:00
abstract：:Children born preterm are at risk for later developmental disorders. The present study examined the predictive effects of neonatal, sociodemographic, and temperament characteristics on behavioral outcomes at toddlerhood, in children born preterm. The sample included 100 toddlers born preterm and with very-low-birth-we...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.09.015
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Children born preterm are at risk for developing reading difficulties and for decrements in other cognitive skills compared to children born at term. AIMS:To assess how domains of function, often negatively impacted by preterm birth, predict reading development in children born preterm and at term. STUDY D...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.01.012
更新日期：2019-03-01 00:00:00
abstract：:Intra-uterine growth restriction (IUGR) is a severe and quite common problem in obstetrics. A condition of placental dysfunction can lead to a cardiovascular adaptation in the fetus characterized by a redistribution of cardiac output to maintain oxygen supply to the heart, adrenal glands and brain - the so-called brai...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.07.006
更新日期：2013-10-01 00:00:00
abstract：:No statistically significant relationships were observed between the red blood cell acid phosphatase polymorphism (ACP-1) and birth weight, duration of gestation and proportion of preterm infants in a large series of newborn infants (greater than 8000) in Cardiff. These results are contrasted with those of a similar, ...
journal_title：Early human development
pub_type： 杂志文章
doi：
更新日期：1988-08-01 00:00:00
abstract：:The diagnosis, acute management and follow-up of neonates with haemolytic disease of the newborn (HDN) still represents a significant area of activity for maternity/neonatal services. ABO incompatability is now the single largest cause of HDN in the western world. However, with increasing knowledge at the molecular le...
journal_title：Early human development
pub_type： 杂志文章,实务指引,评审
doi：10.1016/j.earlhumdev.2008.06.005
更新日期：2008-08-01 00:00:00
abstract：BACKGROUND:Kangaroo care, i.e., skin-to-skin cohabitation (SSC) between an infant and caregiver, is often used in neonatal intensive care units to promote bonding, breastfeeding and infant growth. The direct salutary effects of SSC on cardio-respiratory control in preterm infants remain equivocal; some reports suggest ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.08.015
更新日期：2014-12-01 00:00:00
abstract：:A management programme for the control and treatment of Rh0 (D) immunized during pregnancy is presented. A total of 34,650 births were registered during a 4.5 year period and included 63 D positive newborns to D-immunized mothers. The outcome of all infants has been evaluated according to the severity of the haemolyti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90096-x
更新日期：1987-01-01 00:00:00
abstract：BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) are prescribed in 2-8% during pregnancy. Whether prenatal exposure to SSRIs has long-term effects on the children's development is unknown. AIM:The aim of this study was to determine the effect of prenatal exposure to SSRIs on children's cognitive, motor, and ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105075
更新日期：2020-08-01 00:00:00
abstract：AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00256-0
更新日期：2002-04-01 00:00:00
abstract：INTRODUCTION:In neonates with spina bifida aperta (SBA), leg movements by myotomes caudal to the meningomyelocele (MMC) are transiently observed. It is unclear whether these leg movements relate to functional neural conduction through the MMC. For optimal therapeutical intervention, pathophysiological insight in these ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2005.09.002
更新日期：2006-04-01 00:00:00
abstract：BACKGROUND:Physical and emotional parent-infant closeness activate important neurobiological mechanisms involved in parenting. In a neonatal care context, most research focuses on physical (parental presence, skin-to-skin contact) aspects; insights into emotional closeness can be masked by findings that overemphasise t...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2020.105155
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.09.018
更新日期：2008-06-01 00:00:00
abstract：AIM:To combine meta-analyses of multiple long-term outcomes in children prenatally exposed to methadone or buprenorphine through their mothers' Opioid maintenance therapy (OMT) with a systematic review of similar outcomes in experimental animals. METHOD:The Medline, Embase, Web of Science, CINAHL, Cochrane and Epistem...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2020.104997
更新日期：2020-04-01 00:00:00
abstract：:Posture and spontaneous motor patterns during the first days of life were studied in ten healthy fullterm infants by direct observation and videorecording. The aim of the study was to provide a description of motor and postural characteristics of normal newborns. The infants were recorded for 1 h on their first and fo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(89)90020-0
更新日期：1989-02-01 00:00:00
abstract：BACKGROUND:Patent ductus arteriosus (PDA) is a frequent problem in preterm infants, and its incidence is inversely correlated with gestational age. The efficacy of medical treatment decreases with decreasing gestational age (GA), and failure rates as well as ductus ligation rates of 40% have been reported in <28 week G...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.06.012
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:To date, no study has compared preterm and full term auditory environments. AIM:To define differences in auditory exposure for preterm infants at term equivalent age in the neonatal intensive care unit (NICU) compared to auditory exposure in hospital rooms on a labor and delivery ward after full term birth....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.07.001
更新日期：2019-09-01 00:00:00
abstract：:The relationship between blood glucose and body physique of 233 (42 hypo-and 191 normologycemic) intrauterine growth-retarded neonates was analyzed using different body measurements and indices of body proportions. Classification by combination of weight and length deficit for fetal age revealed that the disproportion...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90027-5
更新日期：1977-10-01 00:00:00
abstract：:The validity of the Wigglesworth experimental model to produce newborn rats that are small for gestational age by ligation of one of both uterine vessels was confirmed. Newborn rats from the opposite horns are used as controls in the classical model. It is concluded from this study that newborns from sham-operated dam...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(79)90038-0
更新日期：1979-09-01 00:00:00
abstract：:805 normal-for-age human embryos and fetuses were used to study early prenatal fat development. The investigation included observations on stages of fat morphogenesis at the light microscopic level and computerized image analyses of fat lobule size and number. The buccal fat pad was selected as a model system for the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90028-2
更新日期：1983-03-01 00:00:00
abstract：INTRODUCTION:Sensitive screening for phenylketonuria (PKU) and other disorders requires accurate measurement of analytes in blood eluted from filter paper. The development of new quantitative methods for phenylalanine measurement in dried blood spots for PKU screening has introduced an increased number of calibrators p...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(96)01762-8
更新日期：1996-07-19 00:00:00
abstract：:The premature birth of a child and admission to the neonatal intensive care unit (NICU) is a distressing experience for parents, and has been associated with symptoms of depression, anxiety and post-traumatic stress. Supporting parents in the NICU after preterm birth is critical not only for their own mental health, b...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2019.104838
更新日期：2019-12-01 00:00:00
abstract：:Nutrition has a key role in the modulation of the developing intestine in early infancy, and nutrients are able to modulate several intestinal functions including nutrient absorption, ion transport, cell growth and differentiation, motility and immunomodulation. Such modulation is exerted in part through a direct inte...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2010.01.008
更新日期：2010-07-01 00:00:00
abstract：:The possibility of assembling this series of Best Practice Guidelines papers pertaining to WASP (Write a Scientific Paper) arose from the international WASP course, and the realisation that the Statistics at Square One papers initially published in the British Medical Journal in the 1970s, dealing with medical statist...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.05.012
更新日期：2019-07-01 00:00:00
abstract：:Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70008-8
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Maternal pre-pregnancy overweight is known to program offspring for adverse health outcomes later in life. AIMS:To investigate how growth patterns of weight, height and BMI from birth to 7years differ according to maternal pre-pregnancy weight (normal weight, overweight and obesity), with specific attention...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2017.06.002
更新日期：2017-10-01 00:00:00
abstract：:According to animal studies myoinositol decreases surfactant phosphatidylglycerol and increases phosphatidylinositol. In the present study lung effluent phospholipids and serum myoinositol were analyzed in respiratory distress syndrome (RDS, 19 cases), in other lung disease (6 cases) and in 22 newborn with no lung dis...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90055-6
更新日期：1985-01-01 00:00:00
