Abstract:
:No statistically significant relationships were observed between the red blood cell acid phosphatase polymorphism (ACP-1) and birth weight, duration of gestation and proportion of preterm infants in a large series of newborn infants (greater than 8000) in Cardiff. These results are contrasted with those of a similar, but smaller, series studied by Bottini's group in Rome, where some apparently significant effects were detected. The Cardiff survey did show a significant relationship between ACP-1 genotypes and the presence or absence of congenital abnormalities, but since this was largely attributable to an excess of ACP-1 CA individuals with abnormalities, a category with a small expected value, further data are required to confirm the validity of this observation.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Ward RDsubject
Has Abstractpub_date
1988-08-01 00:00:00pages
257-64issue
2-3eissn
0378-3782issn
1872-6232pii
0378-3782(88)90013-8journal_volume
17pub_type
杂志文章abstract::The autonomy of patients participating in research means that a proper informed consent process must take place. This means that information must be given according to a reasonable person standard implying what legally and ethical a reasonable person participating in the research would want to know. The research must ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.04.025
更新日期:2018-09-01 00:00:00
abstract::The biochemical, dermatological and neurological motor disorders of biotinidase deficiency (multiple carboxylase deficiency) show a dramatic response to pharmacological doses of biotin. This condition is characterised by the accumulation of biocytin and depletion of biotin. Neuromuscular function returns to normal wit...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90086-6
更新日期:1985-09-01 00:00:00
abstract::Cardiovascular malformations are frequently associated in patients with esophageal atresia (EA). We observed azygos continuation mimicking an aortic arch anomaly in four newborns with type III EA. They presented concomitant rib anomalies indicating a common developmental defect. Foreknowledge is important for planning...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2017.05.007
更新日期:2017-08-01 00:00:00
abstract::Index and regression methods of selecting babies whose heads are out of proportion to their body weight are examined and compared. The ratios head circumference3/birthweight and head circumference3/birthweightP (where P is a power found by regression methods) are used, and the regression of head circumference 3 on bir...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(80)90039-0
更新日期:1980-12-01 00:00:00
abstract::The calculation of descriptive statistics after data collection provides researchers with an overview of the shape and nature of their datasets, along with basic descriptors, and may help identify true or incorrect outlier values. This exercise should always precede inferential statistics, when possible. This paper pr...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2018.02.015
更新日期:2018-03-01 00:00:00
abstract::As major sport events have been cancelled and postponed in response to COVID-19, the necessity to protect and provide a holistic approach to the professional athlete has never been greater. To do so one must understand the negative consequences for athletes in relation to the cancellation and postponement of such even...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105254
更新日期:2020-11-12 00:00:00
abstract:BACKGROUND:Corrected age is typically applied when assessing the development of children born <32 weeks of gestation. There is no consensus as to whether corrected age should be applied when assessing children born late/moderately preterm (LMPT; 32-36 weeks of gestation). AIMS:This study explored the impact of correct...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.01.002
更新日期:2016-03-01 00:00:00
abstract::Relationships between maternal factors associated with very slow and very fast fetal growth rate, and the postnatal growth patterns within groups of 238 small-for-dates (SFD) and 241 large-for-dates (LFD) children were examined. Within the SFD group significant differences were found in their weight, height, and to a ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90036-6
更新日期:1982-12-01 00:00:00
abstract::Fetal cardiac waveform intervals were assessed from fetal magnetocardiogram (FMCG) recordings taken from 59 pregnant women at 17-41 weeks gestation. Beyond 27 weeks' gestation PR and QRS intervals, measured from averaged waveforms, could be obtained from all subjects; however, prior to 21 weeks' gestation the success ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(98)00100-5
更新日期:1999-04-01 00:00:00
abstract:BACKGROUND:Evaluation of cerebellar morphology and measurement of its biometric parameters such as cerebellar vermis height and transverse cerebellar diameter may assist the neonatologist in monitoring cerebellar growth and development and detect abnormalities resulting from malformations, hemorrhage or ischemic infarc...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.10.001
更新日期:2013-12-01 00:00:00
abstract::The objective of this study was to assess minor neurological dysfunction, cognitive development, and somatic development after dexamethasone therapy in very-low-birthweight infants. Thirty-three children after dexamethasone treatment were matched to 33 children without dexamethasone treatment. Data were assessed at th...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.07.004
更新日期:2005-03-01 00:00:00
abstract:AIM:This study examined the rates of follow-up for a cohort of extremely preterm (EP -<28weeks gestation) and/or extremely low birthweight (ELBW -<1000g) children at two years with related perinatal and geographical factors. The secondary aim was to determine the rates of developmental delay and disability. METHODS:A ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.09.012
更新日期:2015-12-01 00:00:00
abstract::Anti-müllerian hormone (AMH) is a glycoprotein produced by immature Sertoli cells and responsible for the regression of müllerian ducts in male fetuses. The ontogeny of the hormone in early human development was investigated. While no detectable AMH could be found in female fetal serum, in males, the mean +/- S.E.M. A...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(93)90204-8
更新日期:1993-06-01 00:00:00
abstract:BACKGROUND:Long-lasting respiratory symptoms have a huge impact on the quality of life in prematurely born children. AIMS:We aimed to investigate the perinatal and maternal risk factors involved in the development of chronic respiratory morbidity in preterm infants, with an emphasis on the importance of Foetal Inflamm...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.07.002
更新日期:2014-09-01 00:00:00
abstract:AIM:This study investigated the effect of aminophylline on behaviour and autonomic function in the preterm period. METHOD:Subjects were preterm infants cared for in the Oita University hospital from August 2012 to October 2014. The group that was administered aminophylline (Am+) and the group that received no aminophy...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.04.011
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:Maternal smoking during pregnancy is associated with a reduction in birth size but very few studies have collated changes in neonatal anthropometry. Our aims were both to assess body composition differences by anthropometry between new-borns from smoking mothers and those from non-smoking mothers, and to show...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.07.015
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Controversy exists regarding association of high levels of proinflammatory cytokines, neonatal morbidities and poor neurodevelopment outcome in very low birth weight infants. OBJECTIVE:To determine association between severity of early inflammatory response and neurodevelopment outcome in high risk very low...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.03.009
更新日期:2011-06-01 00:00:00
abstract::Lenticulostriate vasculopathy (LSV) is a diagnosis dependent on neonatal cranial ultrasound (US). The diagnosis of LSV requires the presence of linear or branching echogenicities in the area of the basal ganglia and/or thalamus on gray scale cranial US. Although the diagnosis of LSV is dependent on cranial US, there a...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2015.04.003
更新日期:2015-07-01 00:00:00
abstract::Lung surfactant was obtained by postmortem lavage from: (A) premature babies: 34 dying acutely within 2 days of birth from Hyaline Membrane Disease (HMD), 20 dying several days after birth with HMD and its consequences, 8 dying from causes other than HMD; (B) mature babies: 24 dying stillborn, 15 dying soon after birt...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90094-1
更新日期:1988-03-01 00:00:00
abstract::Newborn infants, especially preterm infants, have an immature immune system, which is not capable to actively protect against vaccine-preventable infections. Therefore, the newborn is dependent on transplacental transport of Immunoglobulin G (IgG), an active, FcRn receptor mediated process. Fetal IgG rises from approx...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2010.11.003
更新日期:2011-02-01 00:00:00
abstract::The worst of institutional care was brought to public attention in Romania during the 1990s when pictures of severely deprived and malnourished children were shown around the world. However, many European countries have high rates of young children in institutions, where the physical care of the child predominates, wi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.09.018
更新日期:2012-12-01 00:00:00
abstract::Blood flow velocity was measured in both main stem uterine arteries by means of a transvaginally inserted Duplex scanner (240 degrees sector, pulsed Doppler) and visual vessel recognition to investigate normal and abnormal uterine perfusion. Its relationship to fetal circulation and fetal outcome was studied. Fetal ve...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(91)90115-j
更新日期:1991-06-01 00:00:00
abstract:BACKGROUND AND AIM:Turner syndrome (TS) patients have an increased risk of weight gain and metabolic syndrome. To date, it is unknown what factors are involved in this metabolic process, even though it is recognized that TS patients are frequently born small-for-gestational age. The aim of this study was to evaluate th...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.07.014
更新日期:2012-02-01 00:00:00
abstract:AIM:To compare the order and age of emergence of rolling prone to supine and supine to prone before the introduction of back to sleep guidelines and 20 years after their introduction. METHODS:The original normative data for the Alberta Infant Motor Scale (AIMS) were collected just prior to the introduction of back to ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.10.009
更新日期:2013-05-01 00:00:00
abstract::The evolution of ultrasound findings in 59 infants with transient periventricular densities is described and the neurodevelopmental outcome of 53 of these infants was compared with 92 of 107 infants with normal ultrasound scans, born during the same 24-month period. Four of the 53 infants with transient periventricula...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90103-x
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:The entorhinal cortex serves as an important gateway between the cerebral cortex and the hippocampus by receiving afferent information from limbic, modality sensory-specific, and multimodal association fibers from all the brain lobes. AIM:To investigate whether thinning of entorhinal cortex is associated wi...
journal_title:Early human development
pub_type: 临床试验,杂志文章
doi:10.1016/j.earlhumdev.2011.07.017
更新日期:2012-02-01 00:00:00
abstract::Many controversial topics have still to be resolved regarding the nutritional requirements of the newborn, and in particular of the pre-term infant. The term 'controversy' bears the connotation of prolonged dispute and such a situation has arisen for various reasons: (a) from inadequate research methodologies; (b) fro...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(98)00060-7
更新日期:1998-12-01 00:00:00
abstract:PURPOSE:Maternal nutritional status is one of the most important factors of fetal growth and development. Consequently, the currently increasing prevalence of underweight women worldwide has come in the focus of interest of perinatal medicine. The aim of the study was to assess the effect of low pre-pregnancy body mass...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.10.004
更新日期:2013-05-01 00:00:00
abstract:INTRODUCTION:Survivors of congenital diaphragmatic hernia have increased with the introduction of new treatment modalities and have been reported to experience ongoing medical morbidity until adulthood. AIM:To describe the long-term functional impact of congenital diaphragmatic repair on the survivors of a single inst...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.08.025
更新日期:2012-04-01 00:00:00
abstract::Twenty appropriate (mean +/- S.D., gestational age (AGA): 29.9 +/- 1.5 weeks) and 15 small (GA: 34.6 +/- 2.4 weeks) for gestational age (SGA) very low birth weight infants fed banked mature human milk were studied until term for anthropometric parameters: midarm (MAC), chest (CC), head (HC) circumferences, triceps (TS...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(87)90051-x
更新日期:1987-09-01 00:00:00