Challenges of neurodevelopmental follow-up for extremely preterm infants at two years.

Abstract:

AIM:This study examined the rates of follow-up for a cohort of extremely preterm (EP -<28weeks gestation) and/or extremely low birthweight (ELBW -<1000g) children at two years with related perinatal and geographical factors. The secondary aim was to determine the rates of developmental delay and disability. METHODS:A retrospective review of two year follow-up data for all EP and/or ELBW infants born in a large tertiary neonatal hospital over a two year period was undertaken. Neurodevelopmental outcome was assessed using the Bayley Scales of Infant and Toddler Development Scale - 3rd edition (Bayley-III) and neurosensory disability was assessed by a paediatrician using a standard proforma. Rates of delay (composite score≥1SD below mean) were determined using the Bayley-III test norms and a local cohort normative group. Attrition rates and reasons for loss to follow-up were determined. RESULTS:Only 50% (109/219) of eligible children participated in the follow-up. The follow-up rate for children engaged in an ongoing research project was excellent at 98% (58/59), however it was only 32% (51/160) for children following the clinical pathway. The main reason for not attending the follow-up was loss of contact. Factors associated with attendance included a lower gestation, sepsis and living in the metropolitan areas. The rates of delay in this cohort were greater with reference to local cohort normative data compared to Bayley-III test norms with an overall rate of delay of 72% (95%CI, 63% to 81%) compared to 38% (95%CI, 29% to 50%). CONCLUSIONS:Follow-up of EP/ELBW infants to two years is an important part of clinical care, however the high rate of attrition in routine clinical follow-up and consequent difficulty in accurately determining rates of delay highlight challenges for centres providing ongoing care.

journal_name

Early Hum Dev

journal_title

Early human development

authors

L Orton J,McGinley JL,Fox LM,Spittle AJ

doi

10.1016/j.earlhumdev.2015.09.012

subject

Has Abstract

pub_date

2015-12-01 00:00:00

pages

689-94

issue

12

eissn

0378-3782

issn

1872-6232

pii

S0378-3782(15)00204-2

journal_volume

91

pub_type

杂志文章
  • Postnatal changes in skin water content in preterm infants.

    abstract:BACKGROUND:Preterm infants have immature skin, which contributes to skin problems. Very little is known about postnatal changes in the skin, despite the clinical importance of this issue. AIM:To assess temporal changes in skin water content in preterm infants. STUDY DESIGN:A prospective observational study. SUBJECTS...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2015.05.009

    authors: Ishiguro A,Fujinuma S,Motojima Y,Oka S,Komaki T,Saito A,Kawasaki H,Araki S,Kanai M,Sobajima H,Tamura M

    更新日期:2015-09-01 00:00:00

  • Respiratory characteristics of infants with pulmonary hypoplasia syndrome following preterm rupture of membranes: a preliminary study for establishing clinical diagnostic criteria.

    abstract:BACKGROUND:At present, the diagnosis of pulmonary hypoplasia is based on postmortem findings, and there are no clear clinical diagnostic criteria to facilitate its identification and management. AIM:To characterise the respiratory status of pulmonary hypoplasia syndrome (PHS) following preterm rupture of membranes so ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2003.07.002

    authors: Suzuki K

    更新日期:2004-08-01 00:00:00

  • The relationship of prenatal maternal anxiety to infant behavior and mother-infant interaction during the first six months of life.

    abstract::The IPAT Anxiety Scale was administered to a large sample of primiparous women from an economically disadvantaged population in their third trimester of pregnancy. At birth and at three and six months postpartum, the infants and mothers were assessed using a variety of behavioral and standardized procedures. Results i...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(81)90034-7

    authors: Farber EA,Vaughn B,Egeland B

    更新日期:1981-07-01 00:00:00

  • Comparison between the essential fatty acid status of preterm and full-term infants, measured in umbilical vessel walls.

    abstract::The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relat...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(95)01656-n

    authors: Foreman-van Drongelen MM,al MD,van Houwelingen AC,Blanco CE,Hornstra G

    更新日期:1995-08-18 00:00:00

  • Hourly fetal urine production rate in the near-term fetus: is it really increased during fetal quiet sleep?

    abstract::Fetal bladder volume and hourly fetal urine production (HFUPR) is calculated on the assumption that the fetal bladder is ellipsoid in shape. A recent validation study demonstrated a progressive overestimation at increasing bladder volumes. This may be due to changes in shape of the fetal bladder at increasing volumes....

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(97)00049-2

    authors: Stigter RH,Mulder EJ,Visser GH

    更新日期:1998-02-27 00:00:00

  • Maternal smoking and tooth formation in the foetus. I. Tooth crown size in the deciduous dentition.

    abstract::Altogether 2159 pregnancies among black and white Americans in the Collaborative Perinatal Study and dental casts from the children at the age of 5-12 years were studied to find out the effect of maternal smoking on deciduous tooth crown growth. Minor crown size reduction (2-3%) in some dimensions was found in childre...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(92)90086-v

    authors: Heikkinen T,Alvesalo L,Osborne RH,Pirttiniemi P

    更新日期:1992-08-01 00:00:00

  • Perinatal management and long-term cardiac outcome in fetal arrhythmia.

    abstract:BACKGROUND:cardiac arrhythmias are commonly observed in the fetus, however, may have major consequences for fetal development and post natal life. AIMS:to evaluate the perinatal management and cardiac outcome of fetuses with tachy- or bradyarrhythmia. STUDY DESIGN:perinatal management, outcome and long-term cardiac f...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2010.11.001

    authors: Hahurij ND,Blom NA,Lopriore E,Aziz MI,Nagel HT,Rozendaal L,Vandenbussche FP

    更新日期:2011-02-01 00:00:00

  • gamma-Aminobutyric acid concentrations in the cerebrospinal fluid of newborn infants.

    abstract::gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease wi...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(82)90007-x

    authors: Hedner T,Iversen K,Lundborg P

    更新日期:1982-10-01 00:00:00

  • Fetal growth retardation as a cause of impaired ovarian development.

    abstract::Low birthweight has been associated with diseases and disorders later in life. It has been suggested that this is caused by the impaired development of abdominal organs, especially in cases of growth retardation. Besides general malnutrition of the fetus, preferential bloodflow to the heart and brain may further depri...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(97)00073-x

    authors: de Bruin JP,Dorland M,Bruinse HW,Spliet W,Nikkels PG,Te Velde ER

    更新日期:1998-04-17 00:00:00

  • Excretion of cyclic 3',5'-adenosine monophosphate in the early newborn period.

    abstract::The relationship between cyclic 3',5'-adenosine monophosphate (cAMP) excretion and creatinine clearance, urinary phosphate excretion, and urinary osmolarity was studied under basal conditions in 29 babies of 28-40 weeks gestation, during the first few days of life. Urinary cAMP excretion was directly related to creati...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(84)90112-9

    authors: Siegel SR

    更新日期:1984-09-01 00:00:00

  • Prematurity and neonatal noxious events exert lasting effects on infant pain behaviour.

    abstract:BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2007.09.018

    authors: Abdulkader HM,Freer Y,Garry EM,Fleetwood-Walker SM,McIntosh N

    更新日期:2008-06-01 00:00:00

  • Effects of earthquakes and other natural catastrophic events on the sex ratio of newborn infants.

    abstract::Stress due to earthquakes and other natural catastrophic events may result in a decline in the male to female ratio of newborn infants. One reason may be an increased death of male fetuses 3-5 months earlier. Another reason may relate to reduced conception of males and/or early male embryo demise 8-10 months earlier. ...

    journal_title:Early human development

    pub_type: 杂志文章,实务指引

    doi:10.1016/j.earlhumdev.2019.104859

    authors: Fukuda M,Fukuda K,Mason S,Shimizu T,Andersen CY

    更新日期:2020-01-01 00:00:00

  • Thrombopoietin (Tpo) in the fetus and neonate: Tpo concentrations in preterm and term neonates, and organ distribution of Tpo and its receptor (c-mpl) during human fetal development.

    abstract::Little is known about thrombopoietin (Tpo) production in human fetuses and neonates. As a step toward determining whether Tpo is relevant to platelet production in the fetus and neonate, we hypothesized that: (1) like other cytokines, Tpo is present in the cord blood in higher concentrations than in adult plasma; (2) ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(98)00077-2

    authors: Sola MC,Juul SE,Meng YG,Garg S,Sims P,Calhoun DA,Dame JB,Christensen D

    更新日期:1999-01-01 00:00:00

  • Evidence of economic deprivation and female foeticide in a United Nations global births by gender data set.

    abstract:INTRODUCTION:The male-to-female ratio of live births is expressed as the ratio of male births divided by total births (M/F). Males are produced approximately 3% in excess. A large number of factors have been found to influence M/F. Stress and privation reduces M/F. Gender preference (which almost invariably favours mal...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2015.10.013

    authors: Grech V

    更新日期:2015-12-01 00:00:00

  • Uteroplacental insufficiency decreases small intestine growth and alters apoptotic homeostasis in term intrauterine growth retarded rats.

    abstract::Human and animal studies demonstrate that uteroplacental insufficiency and subsequent intrauterine growth retardation (IUGR) decrease intestinal growth and lead to both an increased incidence of feeding intolerance and necrotizing enterocolitis. Our objective was to determine the effects of uteroplacental insufficienc...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2004.04.015

    authors: Baserga M,Bertolotto C,Maclennan NK,Hsu JL,Pham T,Laksana GS,Lane RH

    更新日期:2004-09-01 00:00:00

  • Zinc deficiency: a problem with preterm breast milk.

    abstract::We report a breast-fed preterm infant (31 weeks gestation) who developed nutritional zinc deficiency 13 weeks post delivery. Serial samples of his mothers breast milk from early lactation (2 weeks post delivery) contained very low zinc concentrations, although her serum zinc and sweat zinc concentrations were normal. ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(85)90062-3

    authors: Murphy JF,Gray OP,Rendall JR,Hann S

    更新日期:1985-01-01 00:00:00

  • Gestational diabetes and its effect on the umbilical cord.

    abstract::The structural changes in the umbilical cord of full term fetuses from 18 cases of gestational diabetes were studied. All these were insulin-dependent and their blood glucose levels were well controlled. Light microscopy showed rupture and erosion of the endothelial lining of umbilical arteries resulting in increased ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(86)90114-3

    authors: Singh SD

    更新日期:1986-10-01 00:00:00

  • Predictors of hospitalization for acute lower respiratory infections during the first two years of life in a population of preterm infants with bronchopulmonary dysplasia.

    abstract:BACKGROUND:There have been few research studies aimed at obtaining a better understanding of the prediction of subsequent respiratory morbidity at follow-up in infants with a previous history of bronchopulmonary dysplasia (BPD) living in low- and middle-income countries (LMIC). The aim of the present study was to ident...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2018.10.003

    authors: Acuña-Cordero R,Sossa-Briceño MP,Rodríguez-Martínez CE

    更新日期:2018-12-01 00:00:00

  • The effect of perinatal factors on cord thyroxine concentration.

    abstract::Cord blood thyroxine (T4) concentrations were measured in 4,068 infants from 28 wk gestation to term. Each chart was reviewed for the following factors: delivery by cesarean section, prolonged rupture of membranes, neonatal asphyxia, meconium-stained amniotic fluid, maternal diabetes mellitus and twinning. Each neonat...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(78)90031-2

    authors: Erenberg A

    更新日期:1978-09-01 00:00:00

  • A low incidence of preoperative neurosonographic abnormalities in neonates with heart defects.

    abstract:BACKGROUND AND AIM:To investigate whether neonates with prenatally detected congenital heart defects (CHD) demonstrate cerebral abnormalities on early preoperative cranial ultrasound (CUS), compared to healthy neonates, and to measure brain structures to assess brain growth and development in both groups. STUDY DESIGN...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2020.105097

    authors: Jansen FAR,Haak MC,van Wesemael MS,Ten Harkel ADJD,van Lith JMM,Blom NA,Steggerda SJ

    更新日期:2020-09-01 00:00:00

  • The adverse effect on fetal hemogram by preeclampsia: marked anisocytosis with normocytic, normochromic erythrocythemia as well as thrombocytopenia.

    abstract::Whether preeclampsia affects the fetal hematologic system still remains a controversial issue. The purpose of this series was to examine the hypothesis that preeclampsia may or may not cause adverse effects on fetal hemogram, including erythrocytes, leukocytes, and platelets. In addition, no one, to date, has reported...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(94)90150-3

    authors: Huang SC,Chang FM

    更新日期:1994-05-01 00:00:00

  • Bi-directional activation of inflammation and coagulation in septic neonates.

    abstract::Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to...

    journal_title:Early human development

    pub_type: 杂志文章,评审

    doi:10.1016/S0378-3782(14)70008-8

    authors: Del Vecchio A,Stronati M,Franco C,Christensen RD

    更新日期:2014-03-01 00:00:00

  • Fluconazole prophylaxis in preterm infants: a multicenter case-controlled analysis of efficacy and safety.

    abstract:BACKGROUND:Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS:We conducted a case-co...

    journal_title:Early human development

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/S0378-3782(14)70026-X

    authors: Kaufman DA,Morris A,Gurka MJ,Kapik B,Hetherington S

    更新日期:2014-03-01 00:00:00

  • The relationship between heart rate and eye movement in the human fetus at 38-40 weeks of gestation.

    abstract::The purpose of this study was to compare two different methods for assessing fetal heart rate (FHR)--fetal eye movement (FEM) synchronization: (1) periods of high (HV) and low (LV) variability in the FHR and the presence (EM) and absence (NEM) of FEM were determined by visual inspection and the degree of association b...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(92)90137-6

    authors: Groome LJ,Singh KP,Burgard SL,Neely CL,Bartolucci AA

    更新日期:1992-09-01 00:00:00

  • Fetal breathing movements--a comparison of hard copy records produced by M-mode and Doppler ultrasound.

    abstract::To precisely measure the events of the fetal breath cycle it is necessary to have an accurate hard copy record. Two approaches to this have been made using either M-mode or Doppler ultrasound. It was the aim of this paper to compare these methods. Hard copy records of fetal breathing movements were produced by simulta...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(89)90010-8

    authors: Trudinger BJ,Cook CM

    更新日期:1989-12-01 00:00:00

  • Influence of lung function and reflex activity on the success of patient-triggered ventilation.

    abstract::The influence of lung function and reflex activity on the success of patient-triggered ventilation (PTV) has been determined. Lung function was assessed by measurement of compliance using a single breath technique. Reflex activity was assessed by measurement of the strength of Hering Breuer reflex indicated by the deg...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(94)90142-2

    authors: Chan V,Greenough A,Muramatsu K

    更新日期:1994-04-30 00:00:00

  • The relative accuracy of mercury, Tempa-DOT and FeverScan thermometers.

    abstract::This project aimed to assess the accuracy of Tempa-DOT and FeverScan for measuring children's temperatures. Tempa-DOT is a small flat chemical thermometer with 50 dots that change colour at specific temperatures. FeverScan is a liquid crystal strip thermometer with temperature sensitive colour bars that change colour ...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/s0378-3782(98)00050-4

    authors: Morley C,Murray M,Whybrew K

    更新日期:1998-12-01 00:00:00

  • Withholding treatment, withdrawing treatment, and palliative care in the neonatal intensive care unit.

    abstract::Advances in pharmacology and technology have sharply reduced mortality of extremely preterm infants at the expense of an increasing number of survivors with handicaps and disabilities. The EURONIC study among neonatal intensive care units across Europe demonstrates that treatment of infants born at the limits of viabi...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2005.10.004

    authors: Walther FJ

    更新日期:2005-12-01 00:00:00

  • Postural development in very low birth weight and normal birth weight infants.

    abstract::In this study the seven postural responses selected by Vojta to evaluate neuromotor development were applied to 68 very low birth weight (VLBW) (greater than 1500 g) infants and to 28 healthy infants of normal birth weight (less than 2500 g). Of the 68 VLBW infants, 41 were small for gestational age and 27 appropriate...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/0378-3782(90)90140-e

    authors: Molteno C,Magasiner V,Sayed R,Karplus M

    更新日期:1990-11-01 00:00:00

  • Does perinatal asphyxia contribute to neurological dysfunction in preterm infants?

    abstract:BACKGROUND:Children born preterm are known to be at risk for neurodevelopmental disorders. The role of perinatal asphyxia in this increased risk is still a matter of debate. AIM:To analyze the contribution of perinatal asphyxia in a population of preterm infants admitted to a secondary paediatric setting to neurologic...

    journal_title:Early human development

    pub_type: 杂志文章

    doi:10.1016/j.earlhumdev.2010.06.003

    authors: van Iersel PA,Bakker SC,Jonker AJ,Hadders-Algra M

    更新日期:2010-07-01 00:00:00