Abstract：
:According to animal studies myoinositol decreases surfactant phosphatidylglycerol and increases phosphatidylinositol. In the present study lung effluent phospholipids and serum myoinositol were analyzed in respiratory distress syndrome (RDS, 19 cases), in other lung disease (6 cases) and in 22 newborn with no lung disease. In addition, myoinositol was studied in amniotic fluid and in serum from umbilical vessels and from maternal vein (15 healthy newborn). There was a significant correlation between the fetal and amniotic fluid levels of myoinositol, but no detectable correlation between fetal and maternal myoinositol. Serum myoinositol was higher in preterm than in term newborns. In healthy newborns there was a negative correlation between lung effluent phosphatidylglycerol (expressed as percent of the phospholipids) and serum myoinositol (r = -0.968), and a positive linear correlation between myoinositol and lung effluent phosphatidylinositol (r = 0.849). In RDS at birth, undetectable phosphatidylglycerol corresponded with high serum myoinositol. During the first 5 neonatal days serum myoinositol either (1) decreased and phosphatidylglycerol appeared, (2) remained high and phosphatidylglycerol correspondingly low in some small preterm infants, or (3) decreased but phosphatidylglycerol did not expectedly increase and disaturated lecithin/sphingomyelin ratio remained low in other small preterm babies. We propose that a premature decrease in serum myoinositol among small preterm infants with RDS is not beneficial, since myoinositol may promote hormone-induced lung maturation and healing of lung damage.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Hallman M,Saugstad OD,Porreco RP,Epstein BL,Gluck Ldoi
10.1016/0378-3782(85)90055-6subject
Has Abstractpub_date
1985-01-01 00:00:00pages
245-54issue
3-4eissn
0378-3782issn
1872-6232pii
0378-3782(85)90055-6journal_volume
10pub_type
杂志文章abstract：:Management of neonatal hydronephrosis is a clinical challenge. The natural history of hydronephrosis has shown that most resolve spontaneously; however, there are a significant number that do not. Although hydronephrosis does not always mean obstruction, it becomes the clinician's role to determine when obstruction wi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2005.11.004
更新日期：2006-01-01 00:00:00
abstract：:We describe the managment of 2 sets of pre-term quadruplets born to 2 women pregnant concurrently following the induction of ovulation with gonadotrophin. Careful antenatal planning was necessary to provide for each of the 8 pre-term infants a standard of neonatal medical and nursing care comparable to that normally a...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90028-7
更新日期：1977-10-01 00:00:00
abstract：BACKGROUND:Preterm birth is a known risk factor for infant development but it is less clear whether fetal growth restriction (FGR) and early term birth between 37 and 39 weeks gestation are associated with risks for infant development. AIMS:This study investigated risk factors for adverse developmental outcomes at 12 ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.104951
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Septic complications lead to a high mortality rate in very low birthweight infants (VLBWI). Therefore, prognostic markers for the development of sepsis attach importance to start an efficient therapy as early as possible. AIMS:Functional and phenotypical variables of blood monocytes in the cord and peripher...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00245-6
更新日期：2002-04-01 00:00:00
abstract：:gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease wi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(82)90007-x
更新日期：1982-10-01 00:00:00
abstract：BACKGROUND:Transcutaneous bilirubin (TcB) measurement is widely used as screening for neonatal hyperbilirubinaemia. AIMS:To prospectively validate TcB measurement using hour-specific nomogram in identifying newborn infants not at risk for severe hyperbilirubinaemia. STUDY DESIGN:prospective, observational, multicente...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2011.07.001
更新日期：2012-01-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：OBJECTIVE:To compare paired antepartum fetal/maternal COHb ratios in whole blood from control and alloimmunized pregnancies and to examine the relationships between fetal and maternal COHb. METHODS:COHb levels were measured in paired fetal and maternal blood samples obtained at cordocentesis in 47 control and 16 Rh-al...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00079-7
更新日期：2000-06-01 00:00:00
abstract：:To precisely measure the events of the fetal breath cycle it is necessary to have an accurate hard copy record. Two approaches to this have been made using either M-mode or Doppler ultrasound. It was the aim of this paper to compare these methods. Hard copy records of fetal breathing movements were produced by simulta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(89)90010-8
更新日期：1989-12-01 00:00:00
abstract：BACKGROUND:Birthweight is an important predictor of various fundamental aspects of childhood health and development. AIM:To examine the impact of birthweight on childhood balance performance classification and verify if this is replicable and consistent in different populations. STUDY DESIGN:Prospective birth cohort ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.01.010
更新日期：2019-03-01 00:00:00
abstract：:The study set out to document child care practices in as many different countries and cultures as possible with the aim of providing baseline child care data and stimulating new hypotheses to explain persisting differences in sudden infant death syndrome (SIDS) rates between countries. The protocol, piloted in four co...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/s0378-3782(99)00021-3
更新日期：1999-06-01 00:00:00
abstract：:Placental tissue from five women undergoing elective caesarean did not present differences in fatty acids or mRNA expression of FATP-1, FATP-4 and H-FABP in different placental locations. mRNA expression of FATP-1 and FATP-4 was significantly higher than H-FABP. The expression of L-FABP was too low in placenta for acc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.02.001
更新日期：2006-10-01 00:00:00
abstract：:The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relat...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01656-n
更新日期：1995-08-18 00:00:00
abstract：BACKGROUND:Intrauterine growth restriction (IUGR) is a fetal condition characterized by growth-rate reduction. Afflicted fetuses tend to display abnormalities in heart rate. OBJECTIVE:To study the differences in the heart-rate variability of low-risk fetuses and IUGR fetuses during different behavioral states. METHOD...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.07.002
更新日期：2013-10-01 00:00:00
abstract：:28 polygraphic recordings were made in normal infants: 20 in full-term newborns and 8 in 2- to 10-wk-old babies. In full-term newborns sighs and apneas (greater than 5 sec) were significantly more numerous in active (REM) sleep, while startles prevailed in quiet (NREM) sleep. The incidence of all these events diminish...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(78)90051-8
更新日期：1978-04-01 00:00:00
abstract：:A method has been developed for long-term continuous recordings of several physiological variables in humans, including body movements, core temperature, heart rate and respiratory rate. This method enabled us to study circadian rhythms of body temperature and rest-activity in preterm infants. In 5 out of 9 infants (r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90137-8
更新日期：1990-08-01 00:00:00
abstract：:This century has seen marked improvement in perinatal outcomes but prematurity remains a problem the world over. To improve these results requires more attention to early pregnancy or even pre-pregnancy care. Control of pre-existing conditions, improved social behavior in nutrition, smoking cessation and other factors...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90064-n
更新日期：1992-06-01 00:00:00
abstract：:Unlike the defined role of angiotensin-converting enzyme (ACE) gene in adult hypertension, ACE gene did not show direct influence on childhood blood pressure (BP), rather, seemed to be related to childhood growth with age-dependent characteristics. Thus, we examined intermediate effects of postnatal growth between the...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.10.008
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Acidemia at birth is very common but little is known about its long-term consequences. AIM:To determine if pH at birth is related to established tests of intellectual function. SUBJECTS:School children aged 6-8, for whom obstetric data were available, who had been delivered after labour at term, and had an...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.02.002
更新日期：2008-01-01 00:00:00
abstract：:The magnitude of inflating pressure necessary for effective resuscitation was examined in 70 preterm infants. The median pressure to cause adequate chest wall expansion was 22.8 cmH2O; no infant required a peak inflating pressure greater than 30 cmH2O. No further increase in inflation pressure was used during resuscit...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90045-5
更新日期：1991-07-01 00:00:00
abstract：:A fetus with signs of hydrops is at high risk of intrauterine death. The pathophysiology of hydrops fetalis is still unclear. We found decreased concentrations of cyclic guanosine monophosphate in fetal plasma of alloimmunized pregnancies complicated by hydrops fetalis, which might suggest reduced nitric oxide product...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00063-8
更新日期：2000-03-01 00:00:00
abstract：:Cardiorespiratory interactions in healthy full term newborns were investigated. Spectral analysis was used on heart rate and breathing data from 22 neonates 2-5 days old to reveal coincident frequencies in the breathing and heart rate variability (HRV) spectra, thus identifying respiratory sinus arrhythmia (RSA). The ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(93)90197-3
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Zinc and copper are essential for preterm infants, but recommended requirements from different groups vary widely. Recommended zinc intakes have steadily increased over the years. Although this would be expected to impair copper absorption, recommended copper intakes have not risen in parallel. OBJECTIVES:T...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.08.001
更新日期：2013-10-01 00:00:00
abstract：BACKGROUND:Mothers have been shown to have higher morning cortisol on days they go to work compared to non-workdays; however, it is unknown how maternal workday associates with child morning cortisol or the attunement of mother-child morning cortisol. AIMS:This study examined the presence and stability of morning cort...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.11.007
更新日期：2014-01-01 00:00:00
abstract：BACKGROUND:To date, no study has compared preterm and full term auditory environments. AIM:To define differences in auditory exposure for preterm infants at term equivalent age in the neonatal intensive care unit (NICU) compared to auditory exposure in hospital rooms on a labor and delivery ward after full term birth....
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2019.07.001
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:Practically all reference curves for Doppler blood flow variables in pregnancy end at 40 weeks. OBJECTIVE:To study fetal and uteroplacental circulatory changes in pregnancies proceeding beyond 43 weeks. STUDY DESIGN:Longitudinal comparisons from 42 to 43 weeks and comparisons with controls at term. MATERI...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(96)01736-7
更新日期：1996-09-20 00:00:00
abstract：BACKGROUND:Preterm infants have immature skin, which contributes to skin problems. Very little is known about postnatal changes in the skin, despite the clinical importance of this issue. AIM:To assess temporal changes in skin water content in preterm infants. STUDY DESIGN:A prospective observational study. SUBJECTS...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.05.009
更新日期：2015-09-01 00:00:00
abstract：AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00256-0
更新日期：2002-04-01 00:00:00
abstract：BACKGROUND:Pregnant women's sleep disturbance due to fetal movement is well known. Fetal movement is thought to be an index of fetal well-being. However, as there has never been a way to easily and reliably record fetal movement, psychophysiological studies of pregnant women's sleep disturbance and fetal well-being hav...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.03.001
更新日期：2008-09-01 00:00:00
abstract：:Index and regression methods of selecting babies whose heads are out of proportion to their body weight are examined and compared. The ratios head circumference3/birthweight and head circumference3/birthweightP (where P is a power found by regression methods) are used, and the regression of head circumference 3 on bir...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(80)90039-0
更新日期：1980-12-01 00:00:00
