Abstract：
:The essential fatty acid (EFA) composition of umbilical vessel walls is increasingly being studied as a longer-term reflection of the fetal EFA status. We evaluated the EFA content of umbilical artery and vein vessel walls in 43 preterm infants and compared it with that of 43 full-term cord vessels. In addition, relations among cord vessel wall fatty acid composition, gestational age (GA) at birth, and anthropometric parameters at birth (weight, head circumference, and length) were explored in the preterm infants. Generally, n-6 and n-3 EFA levels were lower, while levels of EFA deficiency markers were higher in preterm than in term cords, both in the walls of the draining arteries and the supplying vein. In preterm cords, significant correlations were observed between GA at birth and levels of n-6 and n-3 EFAs (positive) and EFA deficiency markers (negative). Birth weight showed significant (P < or = 0.01), positive correlations with n-6 and n-3 EFA levels in the cord artery walls of preterm infants, all after correction for GA at birth. In conclusion, substantial differences between the EFA profiles of preterm and full-term cord vessel walls indicate a lower biochemical EFA status of the preterm than of the term fetus. This lower preterm EFA status might be a reflection of a physiologically lower EFA demand for growth and development of the preterm fetus than of the term fetus.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Foreman-van Drongelen MM,al MD,van Houwelingen AC,Blanco CE,Hornstra Gdoi
10.1016/0378-3782(95)01656-nsubject
Has Abstractpub_date
1995-08-18 00:00:00pages
241-51issue
3eissn
0378-3782issn
1872-6232pii
037837829501656Njournal_volume
42pub_type
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journal_title：Early human development
pub_type： 杂志文章,多中心研究
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pub_type： 杂志文章
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pub_type： 杂志文章
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journal_title：Early human development
pub_type： 杂志文章
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pub_type： 杂志文章
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pub_type： 杂志文章
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