Abstract：
:Spectral analysis was performed on ventilation and instantaneous heart rate data recorded in 15 term infants during quiet sleep in the first week after delivery, and in 11 of these infants during active sleep. There was a close relation between the main peaks of the ventilation spectra and the corresponding histograms of the reciprocals of Ttot. The spectra for instantaneous heart rate showed power at the rate of breathing (HF) and also at lower frequencies, 0.04-0.2 Hz (LF). During quiet sleep, the relative magnitudes of the HF and LF peaks for heart rate were found to depend on the respiratory rate and the variability of Ttot. During active sleep, most of the power in the heart rate spectrum was concentrated in the LF region. Weighted coherences between ventilation and heart rate were higher during quiet than active sleep, both in the HF and LF spectra. LF power was higher during active than quiet sleep in both ventilation and heart rate. The results suggest that the pattern of breathing has a marked effect on the shape of the heart rate spectrum. In most infants, however, there is no fixed phase relationship between oscillations in ventilation and heart rate, at high or low frequencies. These oscillations are affected by sleep state and hence, by implication, by central nervous system rhythm generators.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Hathorn MKdoi
10.1016/0378-3782(89)90050-9subject
Has Abstractpub_date
1989-11-01 00:00:00pages
81-99issue
2eissn
0378-3782issn
1872-6232pii
0378-3782(89)90050-9journal_volume
20pub_type
杂志文章abstract：BACKGROUND:Among preterm infants, high concentrations of inflammatory mediators in cerebrospinal fluid (CSF) are associated with poor outcome. Previous studies have not indicated whether CSF concentrations of inflammatory mediators are associated with important confounders such as gestational age. AIMS:To examine asso...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.10.011
更新日期：2009-04-01 00:00:00
abstract：:There is convincing evidence that breast-feeding is protective against gastro-enteritis and diarrhoea, but for other infections the situation is less clear cut. There is evidence that breast-fed infants are at increased risk of one infection (infant botulism). They are probably not significantly protected from upper r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00056-x
更新日期：1997-10-29 00:00:00
abstract：:The premature birth of a child and admission to the neonatal intensive care unit (NICU) is a distressing experience for parents, and has been associated with symptoms of depression, anxiety and post-traumatic stress. Supporting parents in the NICU after preterm birth is critical not only for their own mental health, b...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2019.104838
更新日期：2019-12-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：OBJECTIVE:A short course of moderately early dexamethasone therapy with a starting dose of 0.5 mg/kg/day improves lung compliance and shortens the duration of ventilatory support in preterm infants with respiratory distress syndrome (RDS). We conducted a double-blind, randomized study to evaluate whether a moderately e...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-3782(03)00082-3
更新日期：2003-10-01 00:00:00
abstract：BACKGROUND:Transcutaneous bilirubin (TcB) measurement is widely used as screening for neonatal hyperbilirubinaemia. AIMS:To prospectively validate TcB measurement using hour-specific nomogram in identifying newborn infants not at risk for severe hyperbilirubinaemia. STUDY DESIGN:prospective, observational, multicente...
journal_title：Early human development
pub_type： 杂志文章,多中心研究
doi：10.1016/j.earlhumdev.2011.07.001
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Patent ductus arteriosus (PDA) is a frequent problem in preterm infants, and its incidence is inversely correlated with gestational age. The efficacy of medical treatment decreases with decreasing gestational age (GA), and failure rates as well as ductus ligation rates of 40% have been reported in <28 week G...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.06.012
更新日期：2010-08-01 00:00:00
abstract：:In this study of 167 neonates who demonstrated a total of 1010 transitions between arousal states, we considered whether specific state transitions were associated with umbilical cord blood lead levels. We found that the arousal patterns of neonates with varying levels (<1, 1-10 and >10 microg/dL) of lead exposure cou...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.06.002
更新日期：2008-04-01 00:00:00
abstract：:Neonatal hyperglycaemia is a frequent complication in VLBW infants during the first week of life. The more common causes include high glucose intake, stress situations such as sepsis, NEC, and surgical treatments, as well as the administration of vasoactive drugs and methylxanthines. The appropriate definition is uncl...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2011.01.005
更新日期：2011-03-01 00:00:00
abstract：BACKGROUND:The osmotic fragility of red blood cells reflects their membrane ability to maintain structural integrity. The osmolality at which the cells lyse is related to their shape, deformability, surface area/volume ratio and intrinsic membrane properties. In cord blood, there may be differences between premature an...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(03)00009-4
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Cases suggestive of non-acidemia related cerebral palsy (CP) are likely misdiagnosed as acidemia related CP because of the presence of nonreasuring fetal heart rate (FHR) patterns. AIMS:Our purpose was to compare intrapartum FHR patterns between the cases of neurological damage and the cases without disabil...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.10.007
更新日期：2009-04-01 00:00:00
abstract：:Blood flow velocity was measured in both main stem uterine arteries by means of a transvaginally inserted Duplex scanner (240 degrees sector, pulsed Doppler) and visual vessel recognition to investigate normal and abnormal uterine perfusion. Its relationship to fetal circulation and fetal outcome was studied. Fetal ve...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(91)90115-j
更新日期：1991-06-01 00:00:00
abstract：AIM:Depression during pregnancy is a significant cause of adverse birth outcomes, and its prevalence has increased in recent years. This study aimed to give an updated quantification of the risk of preterm birth (PTB), low birth weight (LBW) and intrauterine growth restriction (IUGR) that is associated with antenatal d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105243
更新日期：2021-01-01 00:00:00
abstract：:The objective of this work was to examine the changes in the fatty acid profiles of plasma lipid fractions and red blood cell membrane phospholipids in newborn infants during the first 6-8 h of life. Methyl esters of fatty acids from plasma free fatty acids and phospholipids and from membrane phosphatidylethanolamine,...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(87)90041-7
更新日期：1987-03-01 00:00:00
abstract：:Eleven healthy, full-term babies were studied on the second day (d2) after birth and again 4 weeks (w4) later. The babies lived in natural lighting conditions and were fed every 4 h. Blood pressure, heart rate, skin (abdomen) and rectal temperatures were measured at 10-min intervals for 24 h. Behavioural states (deep ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90039-6
更新日期：1994-02-01 00:00:00
abstract：BACKGROUND:The reported national case fatality rates (CFRs) for coronavirus disease 2019 (COVID-19) shows a sex bias with males > females. The relative lengths of the index (2D) and ring (4D) fingers (digit ratio; 2D:4D) is a sexually dimorphic (males < females) proxy of fetal sex steroids (low 2D:4D indicates high pre...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105074
更新日期：2020-07-01 00:00:00
abstract：:Whether preeclampsia affects the fetal hematologic system still remains a controversial issue. The purpose of this series was to examine the hypothesis that preeclampsia may or may not cause adverse effects on fetal hemogram, including erythrocytes, leukocytes, and platelets. In addition, no one, to date, has reported...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90150-3
更新日期：1994-05-01 00:00:00
abstract：:The reactions of heart rate (HR), systolic (sBP) and diastolic (dBP) blood pressure were studied in response to passive head-up tilting (successively to +45 degrees and +90 degrees) in a group of 83 full-term, 1- to 7-day-old newborns who were quiet and awake. A significant mean increase of HR was noted for the whole ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01706-2
更新日期：1996-03-22 00:00:00
abstract：BACKGROUND:Using pure oxygen (PO) in neonatal resuscitation increases oxidative stress and mortality in full-term hypoxic infants. International neonatal resuscitation guidelines recommend air or blended oxygen for resuscitation regardless of gestational age but this requires education and equipment that may not be glo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.01.005
更新日期：2012-08-01 00:00:00
abstract：:Case-control studies are frequently performed in prenatal and perinatal epidemiology. For data collection, these studies often rely on self-administered questionnaires or personal interviews. Although of importance, validation of these measurement instruments received little attention in epidemiologic research so far....
journal_title：Early human development
pub_type： 评论,信件
doi：10.1016/j.earlhumdev.2010.09.372
更新日期：2011-01-01 00:00:00
abstract：BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) are prescribed in 2-8% during pregnancy. Whether prenatal exposure to SSRIs has long-term effects on the children's development is unknown. AIM:The aim of this study was to determine the effect of prenatal exposure to SSRIs on children's cognitive, motor, and ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105075
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Natural cell death due to apoptotic mechanisms has been described in various species. Relatively few studies examined this process in humans. AIM:To investigate the distribution of apoptosis in fetal brain tissue. DESIGN:We examined apoptosis in the frontal region of human fetal brain by the TUNEL method i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(02)00116-0
更新日期：2003-02-01 00:00:00
abstract：OBJECTIVE:To determine whether proportionate or disproportionate foetal smallness at 17 to 19 weeks of gestation in low-risk pregnancies was associated with size, body constitution, and adverse outcome at birth. METHODS:We included ultrasound measurements at 17-19 weeks of gestation in 7285 uncomplicated pregnancies w...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.01.010
更新日期：2006-10-01 00:00:00
abstract：:Forty-four prenatally depressed women were randomly assigned to peer support or interpersonal psychotherapy groups at 22 weeks gestation. The peer support group participated in a 20-minute group session once per week for 12 weeks, and the interpersonal psychotherapy group met for one hour per week for 12 weeks. Assess...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2013.04.006
更新日期：2013-09-01 00:00:00
abstract：BACKGROUND:Retinopathy of prematurity (ROP) is often associated with visual impairment and multiple developmental disabilities. AIMS:As most of the previous studies include infants with brain lesions, that can determine visual impairment per se, a cohort of low neurological risk preterm infants without ROP and with va...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105134
更新日期：2020-09-01 00:00:00
abstract：:28 polygraphic recordings were made in normal infants: 20 in full-term newborns and 8 in 2- to 10-wk-old babies. In full-term newborns sighs and apneas (greater than 5 sec) were significantly more numerous in active (REM) sleep, while startles prevailed in quiet (NREM) sleep. The incidence of all these events diminish...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(78)90051-8
更新日期：1978-04-01 00:00:00
abstract：INTRODUCTION:Children born very preterm (VPT) are at increased risk of emotional and behavioral problems later in life. We aimed to determine the prevalence and spectrum of behavioral abnormalities at five years of age in VPT children. METHODS:Multi-center cohort study on 339 early-school aged children born at a gesta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105200
更新日期：2020-12-01 00:00:00
abstract：:221 small-for-dates (SFD) and 244 average-for-dates (AFD) children were personally examined at birth, and seen thereafter at regular intervals up to 4 years, when a thorough assessment was made. There was an excess of SFD children with major congenital abnormalities; but no difference between the groups in the number ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(83)90007-5
更新日期：1983-10-01 00:00:00
abstract：BACKGROUND:The kidney is one organ which presents distinct morphology depending on GA; the classic references for kidney measurements were established several years ago and it is not certain if they are still accurate. AIM:To evaluate the renal maturity using a computer-assisted morphometry in autopsied fetuses within...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.01.013
更新日期：2006-11-01 00:00:00
abstract：:Among 7 subjects with hyperemesis gravidarum (HG), we found gabapentin therapy to be associated with mean reductions in nausea and emesis from Baseline to Days 12-14 of 80% and 94%, respectively. There have been 2 congenital defects among 7 exposed infants. Gabapentin may be effective in the treatment of HG. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2009.11.003
更新日期：2010-01-01 00:00:00
