Abstract：
OBJECTIVE:To determine whether proportionate or disproportionate foetal smallness at 17 to 19 weeks of gestation in low-risk pregnancies was associated with size, body constitution, and adverse outcome at birth. METHODS:We included ultrasound measurements at 17-19 weeks of gestation in 7285 uncomplicated pregnancies with reliable information on last menstrual period. We considered a foetus with both mean abdominal diameter (MAD) and biparietal diameter (BPD) below the 10th percentile for gestational age, gender, and parity as symmetrically small. Those who had MAD below the 10th percentile and BPD at or above the 10th percentile were asymmetrically small (thin and small). RESULTS:The occurrence of small for gestational age (SGA) (birth weight below the 10th percentile) decreased with increasing second trimester MAD percentile (P<0.0001). The risk in foetuses which were both thin and extremely small (MAD below the 2.5th percentile) of having weight, ponderal index, crown-heel length, or head circumference below the 10th percentile at birth was 19-28%. The risk of perinatal composite outcome (prenatal death, Apgar score after 5 min < or =7, birth weight below the 10th percentile, or <1500 g, or preterm birth) was 37%. Apgar score of < or =7 at 5 min and explained foetal death both occurred in 7%, which was significantly higher than those with larger MAD. CONCLUSION:Asymmetric as well as symmetric foetal smallness may start early in pregnancy. Symmetric and particularly asymmetric small foetuses at 17-19 weeks of gestation were generally lighter, shorter, and thinner at birth and had more often adverse perinatal outcome.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Rasmussen S,Kiserud T,Albrechtsen Sdoi
10.1016/j.earlhumdev.2006.01.010keywords:
subject
Has Abstractpub_date
2006-10-01 00:00:00pages
683-90issue
10eissn
0378-3782issn
1872-6232pii
S0378-3782(06)00041-7journal_volume
82pub_type
杂志文章abstract：OBJECTIVE:To establish longitudinal reference ranges for the fetal superior mesenteric artery (SMA) flow velocity and pulsatility index (PI(SMA)). Also to examine the hemodynamic relationship to venous liver perfusion and umbilical flow distribution in the liver, to other splanchnic arteries, and more generally to the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.09.412
更新日期：2009-04-01 00:00:00
abstract：:Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2008.11.009
更新日期：2009-02-01 00:00:00
abstract：AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00256-0
更新日期：2002-04-01 00:00:00
abstract：:The fatty acid content of fetal tissues was utilized to estimate essential fatty acid accretion during intrauterine growth. These rates of essential fatty acid accretion were used to predict that 400 mg/kg of body weight for omega-6 fatty acids and 50 mg/kg of body weight for omega-3 fatty acids per day would be used ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(81)90016-5
更新日期：1981-09-01 00:00:00
abstract：INTRODUCTION:Reduced left ventricular (LV) diastolic function can exert significant load to the right ventricle (RV) that can affect RV-pulmonary vasculature (PV) coupling. RV-PV can be assessed with the RV length-force relationship (tricuspid annular plane systolic excursion [TAPSE] to pulmonary artery acceleration ti...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.11.006
更新日期：2019-01-01 00:00:00
abstract：:In a prospective clinical study from an unselected, area-based population, the influence on birthweight for gestational age of different factors was studied, with special respect to 15 risk factors for intrauterine growth retardation (IUGR) recognizable in early pregnancy. In the multiple regression analyses performed...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90110-5
更新日期：1984-09-01 00:00:00
abstract：:A new protocol for structured observation of motor performance in infants, SOMP-I, was applied to 72 neonatally healthy fullterm infants at 0, 2, 4, 6 and 10 months of age. It contains 13 items, formed as ascending scales, consisting of detailed descriptions of motor performance in different body positions and body pa...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)01598-J
更新日期：1995-01-30 00:00:00
abstract：:Fifty-five pregnant Rhesus isoimmunized women were subjected to fetal blood sampling or fetal blood transfusion on 135 occasions. Glucose and C-peptide concentrations were measured in fetal blood, in addition to the routine investigations for complete blood count, blood gases and lactate concentration, in order to inv...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(90)90027-g
更新日期：1990-12-01 00:00:00
abstract：BACKGROUND:Human milk contains a range of host defence proteins that appear to contribute to health and wellbeing, but their variability in abundance among individuals has not been very well characterised. Milk from mothers of premature infants has altered composition, but the effect of gestation length on the host-def...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：:Among 7 subjects with hyperemesis gravidarum (HG), we found gabapentin therapy to be associated with mean reductions in nausea and emesis from Baseline to Days 12-14 of 80% and 94%, respectively. There have been 2 congenital defects among 7 exposed infants. Gabapentin may be effective in the treatment of HG. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2009.11.003
更新日期：2010-01-01 00:00:00
abstract：PURPOSE:Maternal nutritional status is one of the most important factors of fetal growth and development. Consequently, the currently increasing prevalence of underweight women worldwide has come in the focus of interest of perinatal medicine. The aim of the study was to assess the effect of low pre-pregnancy body mass...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.10.004
更新日期：2013-05-01 00:00:00
abstract：:We report a breast-fed preterm infant (31 weeks gestation) who developed nutritional zinc deficiency 13 weeks post delivery. Serial samples of his mothers breast milk from early lactation (2 weeks post delivery) contained very low zinc concentrations, although her serum zinc and sweat zinc concentrations were normal. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90062-3
更新日期：1985-01-01 00:00:00
abstract：BACKGROUND:The requirement of essential fatty acids (EFA) for the development of the brain is well documented. OBJECTIVE:To investigate the early neurological development at term and 44 weeks gestational age in preterm infants in relation to EFA concentrations in breast milk and in infants' and mothers' plasma phospho...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.05.017
更新日期：2010-07-01 00:00:00
abstract：:In the face of evidence of human milk contamination by organochlorine pesticides, an analysis was performed on samples of milk obtained from healthy lactating women in the provinces of Granada and Almeria in Southern Spain. The samples were obtained by the Neonate Section of the Department of Pediatrics of Granada Uni...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(01)00221-3
更新日期：2001-11-01 00:00:00
abstract：:Improvements in perinatal and neonatal management have not only led to a higher survival rate of very low birth weight infants (VLBW; < or = 1,500 g or < 32 weeks gestational age), but also to a better outcome of these children. However the percentage of VLBW children who need special education because of later school...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00056-0
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Pregnant women's sleep disturbance due to fetal movement is well known. Fetal movement is thought to be an index of fetal well-being. However, as there has never been a way to easily and reliably record fetal movement, psychophysiological studies of pregnant women's sleep disturbance and fetal well-being hav...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.03.001
更新日期：2008-09-01 00:00:00
abstract：:In 1% of monozygotic twin pregnancies, one fetus is without a heart; blood circulation is maintained by an accompanying "pump" twin. Such an acardiac condition is usually diagnosed on the basis of further malformations visible by ultrasonography. We describe a monoamniotic twin pregnancy with early growth reduction in...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00011-5
更新日期：1998-08-28 00:00:00
abstract：BACKGROUND:Routine oropharyngeal suctioning in term vigorous neonates immediately after birth is a questionable practice. Current recommendations favor suctioning only in the presence of considerable obstruction due to secretions, blood or other matter. We aimed to analyze the influence of oropharyngeal suctioning on c...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.01.005
更新日期：2015-02-01 00:00:00
abstract：OBJECTIVE:To investigate whether maternal obesity poses a risk for long-term cardiovascular morbidity in the offspring. STUDY DESIGN:Data were analyzed from a non-selective population of all infants born between the years 1991-2014 at the tertiary Soroka University Medical Center (SUMC), the sole hospital in the south...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105221
更新日期：2020-12-01 00:00:00
abstract：BACKGROUND:Evaluation of cerebellar morphology and measurement of its biometric parameters such as cerebellar vermis height and transverse cerebellar diameter may assist the neonatologist in monitoring cerebellar growth and development and detect abnormalities resulting from malformations, hemorrhage or ischemic infarc...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.10.001
更新日期：2013-12-01 00:00:00
abstract：:To determine the assessments before discharge from the intensive care unit, that will predict outcome most accurately, a prospective longitudinal study in a cohort of 79 high risk VLBW children was conducted from birth to 3.6 years of age. Birthweight, gestational age, obstetrical and neonatal optimality, neonatal neu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90040-n
更新日期：1992-12-01 00:00:00
abstract：BACKGROUND:Hydatidiform mole is an abnormal pregnancy with over-proliferation of the placenta, which causes the dysfunction of placenta. Although more than 80% of hydatidiform moles are benign with good outcome, hydatidiform moles are associated with developing very early onset preeclampsia. However the association bet...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.02.008
更新日期：2013-08-01 00:00:00
abstract：:Newborn infants fulfil some criteria of being conscious i.e. being aware of the body, the self and the world. They are able to differentiate between self and nonself touch, express emotions and show signs of shared feelings. They process sensory impressions including pain at a cortical level. They remember rhythmic so...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2009.08.017
更新日期：2009-10-01 00:00:00
abstract：:We assessed the relation of perinatal factors to severe hypothyroxinemia of prematurity, defined as thyroxine value more than 2.6 standard deviations below the mean for newborns. The 365 survivors of birth before 32 weeks gestation were enrolled in a population-based study of the correlates of neonatal brain injury. I...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01843-9
更新日期：1997-01-20 00:00:00
abstract：INTRODUCTION:Many women with a bipolar disorder are of reproductive age and will need to continue lithium treatment during pregnancy. The teratogenic and perinatal effects of lithium are known, but not the long-term effects of lithium on neurodevelopment of the children. This study investigates growth, neurological, co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.09.013
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS:We conducted a case-co...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0378-3782(14)70026-X
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a leading cause of hospitalization for children <1year old and is more severe in premature infants. OBJECTIVE:To assess whether late preterm (LPT) birth is an independent risk factor for RSV hospitalization and more severe RSV disease in children less than 24months old. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.06.009
更新日期：2015-09-01 00:00:00
abstract：AIM:This study investigated the effect of aminophylline on behaviour and autonomic function in the preterm period. METHOD:Subjects were preterm infants cared for in the Oita University hospital from August 2012 to October 2014. The group that was administered aminophylline (Am+) and the group that received no aminophy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.04.011
更新日期：2016-08-01 00:00:00
abstract：:Unlike the defined role of angiotensin-converting enzyme (ACE) gene in adult hypertension, ACE gene did not show direct influence on childhood blood pressure (BP), rather, seemed to be related to childhood growth with age-dependent characteristics. Thus, we examined intermediate effects of postnatal growth between the...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.10.008
更新日期：2012-06-01 00:00:00
abstract：BACKGROUND:Visual cognitive functions of preverbal infants are evaluated by means of a behavioral assessment. Parents or primary caregivers may be appropriate to certify the acquisition of certain abilities. AIMS:To develop the PreViAs (Preverbal Visual Assessment) questionnaire to assess visual behavior of infants un...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.012
更新日期：2014-04-01 00:00:00
