Abstract:
:One hundred consecutive cranial computed tomographic scans were reviewed in children aged 0-2 years, presenting to the Royal Belfast Hospital for Sick Children. The mean age at scanning was 8.3 months and 73% of the scans were abnormal. The majority of scans were performed electively (78%). The commonest indication for a scan was seizures (31) and the diagnostic yield was highest where they were associated with other neuro-developmental symptoms. The usefulness of the CT scan was not limited to the abnormal studies but contributed to management in children with normal scans by excluding important intracranial pathology. Developmental CNS malformation (16 scans) and cerebral atrophy (15 scans) were the most frequent CT abnormalities encountered.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Hill AE,Hicks EMdoi
10.1016/0378-3782(91)90011-qsubject
Has Abstractpub_date
1991-08-01 00:00:00pages
75-81issue
2eissn
0378-3782issn
1872-6232pii
0378-3782(91)90011-Qjournal_volume
26pub_type
杂志文章abstract:BACKGROUND:Movement by an infant during the first year of life might influence its activity level and thereby influence growth in early childhood. AIM:To examine whether the time that an infant is able to move unrestrictedly and time spent in baby seats are related to weight and waist circumference at age 9 months and...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.04.002
更新日期:2013-07-01 00:00:00
abstract::The evolution of ultrasound findings in 59 infants with transient periventricular densities is described and the neurodevelopmental outcome of 53 of these infants was compared with 92 of 107 infants with normal ultrasound scans, born during the same 24-month period. Four of the 53 infants with transient periventricula...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90103-x
更新日期:1988-03-01 00:00:00
abstract:AIM:To determine whether maternal state and trait anxiety levels affect fetal movements or fetal heart rate (FHR) in the third trimester. SUBJECTS:Forty-one healthy pregnant nulliparous women not on medication and with a singleton pregnancy. STUDY DESIGN:Maternal anxiety was assessed using the Spielberger State- Trai...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(01)00256-0
更新日期:2002-04-01 00:00:00
abstract::A method has been developed for long-term continuous recordings of several physiological variables in humans, including body movements, core temperature, heart rate and respiratory rate. This method enabled us to study circadian rhythms of body temperature and rest-activity in preterm infants. In 5 out of 9 infants (r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(90)90137-8
更新日期:1990-08-01 00:00:00
abstract:BACKGROUND:Testosterone (T) is taken or prescribed to enhance appearance, increase athletic performance and libido and to treat hypogonadism. Digit ratio (2D:4D) is thought to be a negative correlate of prenatal T. Here we consider the relationship between 2D:4D and T supplementation. AIMS:Our sample was taken from th...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.104843
更新日期:2019-12-01 00:00:00
abstract::Neonatal hyperglycaemia is a frequent complication in VLBW infants during the first week of life. The more common causes include high glucose intake, stress situations such as sepsis, NEC, and surgical treatments, as well as the administration of vasoactive drugs and methylxanthines. The appropriate definition is uncl...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2011.01.005
更新日期:2011-03-01 00:00:00
abstract::During the period 1978-1990 (12.5 years), 929 neonatal general surgical emergencies were treated at the Seoul National University Children's Hospital. There were 308 anorectal malformations, 128 atresia/stenosis of the gut, 125 neonatal Hirschsprung's disease, 75 gastroschisis and 67 esophageal atresias. The highest o...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90194-l
更新日期:1992-06-01 00:00:00
abstract::Intrauterine growth restriction (IUGR) is associated with altered lung development in human and rat. The transcription factor PPARγ, is thought to contribute to lung development. PPARγ is activated by docosahexanoic acid (DHA). One contribution of PPARγ to lung development may be its direct regulation of chromatin mod...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2010.08.026
更新日期:2010-12-01 00:00:00
abstract::CMV is the most common congenital infection in newborns worldwide. Congenital CMV causes sensorineural hearing loss in a significant proportion of infected newborns, while the majority of newborns are asymptomatic. In the last three years there have been significant advances in the diagnosis and treatment of congenita...
journal_title:Early human development
pub_type: 杂志文章,实务指引
doi:10.1016/j.earlhumdev.2011.08.021
更新日期:2011-11-01 00:00:00
abstract::Prior research in newborns has shown that head-up and head-down tilting elicits sustained increases and decreases in heart rate, respectively. Other studies in older infants have suggested that the pattern of heart rate responses to head-up tilting varies with risk for sudden infant death syndrome (SIDS). In this stud...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(99)00026-2
更新日期:1999-07-01 00:00:00
abstract::The objective of this study was to assess minor neurological dysfunction, cognitive development, and somatic development after dexamethasone therapy in very-low-birthweight infants. Thirty-three children after dexamethasone treatment were matched to 33 children without dexamethasone treatment. Data were assessed at th...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.07.004
更新日期:2005-03-01 00:00:00
abstract::Increasing public awareness of the prone sleeping position, maternal smoking and overheating as potentially avoidable risk factors for the sudden infant death syndrome (SIDS) has been accompanied by a dramatic reduction in mortality. The results of two population based studies of SIDS in Avon are compared; the first o...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90208-9
更新日期:1994-09-15 00:00:00
abstract::198 infants were followed up from birth until 4 1/2-5 years to observe the development of eczema and asthma and its relation to infant feeding. Findings here refer only to eczema. Comparison between those initially breastfed, regardless of duration, and those fed on cows milk preparations showed little difference in t...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90039-2
更新日期:1984-04-01 00:00:00
abstract::Several guidelines have been created in an attempt to raise the quality of different kinds of studies. These also attempt to ensure that research is reported accurately and transparently. Six such guidelines (CONSORT, MOOSE, PRISMA, SPIRIT, STARD, and STROBE) will be briefly discussed in this paper. The purpose of the...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.05.014
更新日期:2019-07-01 00:00:00
abstract::Data on the postnatal growth patterns of 238 small-for-gestational age (SGA) and 241 large-for-gestational age (LGA) babies are presented. Three proportionality ratios were selected; and their changes in shape, by these indices, during the first 7 years are compared with a random sample of 284 children drawn from the ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(86)90095-2
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:Higher parenting stress in mothers of children born very preterm may be in part a response to poorer neurobehavioral development, reflecting realistic concerns in addition to adaptation to the trauma of preterm delivery. To our knowledge, there are few longitudinal studies of parenting stress that have addre...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.01.030
更新日期:2011-04-01 00:00:00
abstract:UNLABELLED:During the previous two decades smoking among pregnant women in the developed world declined by about 60-75%. Nevertheless, prenatal smoking remains a common habit and accounts for a significant proportion of fetal morbidity and mortality through both a direct (fetal) and an indirect (placental) effect. The ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2007.08.002
更新日期:2007-11-01 00:00:00
abstract:BACKGROUND:Preterm infants have immature skin, which contributes to skin problems. Very little is known about postnatal changes in the skin, despite the clinical importance of this issue. AIM:To assess temporal changes in skin water content in preterm infants. STUDY DESIGN:A prospective observational study. SUBJECTS...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.05.009
更新日期:2015-09-01 00:00:00
abstract::The study set out to document child care practices in as many different countries and cultures as possible with the aim of providing baseline child care data and stimulating new hypotheses to explain persisting differences in sudden infant death syndrome (SIDS) rates between countries. The protocol, piloted in four co...
journal_title:Early human development
pub_type: 杂志文章,多中心研究
doi:10.1016/s0378-3782(99)00021-3
更新日期:1999-06-01 00:00:00
abstract::The potential use of a piglet as a model for investigation of brain blood flow was evaluated by assessing the presence of autoregulation in 11 spontaneously breathing newborn piglets. Blood pressure was altered by phlebotomy. When the mean arterial blood pressure was greater than 50 mm Hg, no significant change in bra...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(82)90063-9
更新日期:1982-01-01 00:00:00
abstract::Twenty-seven 5--8-day-old babies were filmed during normal breast feeding (one feed each). Sucking patterns were determined from the film from a total sample of 17,676 sucks. Intersuck interals fell on two distributions: one of intervals between sucks during bursts of sucking (1.3 sec and less), and the other of rests...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(79)90042-2
更新日期:1979-12-01 00:00:00
abstract::There is convincing evidence that breast-feeding is protective against gastro-enteritis and diarrhoea, but for other infections the situation is less clear cut. There is evidence that breast-fed infants are at increased risk of one infection (infant botulism). They are probably not significantly protected from upper r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00056-x
更新日期:1997-10-29 00:00:00
abstract::No statistically significant relationships were observed between the red blood cell acid phosphatase polymorphism (ACP-1) and birth weight, duration of gestation and proportion of preterm infants in a large series of newborn infants (greater than 8000) in Cardiff. These results are contrasted with those of a similar, ...
journal_title:Early human development
pub_type: 杂志文章
doi:
更新日期:1988-08-01 00:00:00
abstract:BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.01.006
更新日期:2014-03-01 00:00:00
abstract:BACKGROUND:It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. AIMS:To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. STUDY DESIGN:Retrospective cohort stu...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.03.006
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Preterm infants have a high risk of cranial deformity resulting from external pressures. Such deformity is associated with delayed neurodevelopment. AIMS:We aimed to clarify the effects of continuous use of positioning pillows on cranial deformity and neurodevelopment in preterm infants. METHODS:This prosp...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105137
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:The reported national case fatality rates (CFRs) for coronavirus disease 2019 (COVID-19) shows a sex bias with males > females. The relative lengths of the index (2D) and ring (4D) fingers (digit ratio; 2D:4D) is a sexually dimorphic (males < females) proxy of fetal sex steroids (low 2D:4D indicates high pre...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105074
更新日期:2020-07-01 00:00:00
abstract::Six month infant-mother interaction patterns were observed and 10 month Bayley MDI scores were obtained in 10 fullterm and 14 healthy preterm (less than 37 weeks) infants. Relationships among interaction parameters and intellectual performance are compared with those among earlier interaction patterns and development....
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(86)90008-3
更新日期:1986-04-01 00:00:00
abstract::Maturation of spontaneous fetal body and breathing movements of 24- to 33-week-old fetuses in 168 pregnancies threatening to deliver prematurely were examined on the basis of newborn outcome (premature compromised, premature healthy, term healthy). Maturation of fetuses in 60 low-risk pregnancies delivering as healthy...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(99)00007-9
更新日期:1999-05-01 00:00:00
abstract::Pulse oximetry screening for critical congenital heart defects (CCHDs) is a highly specific, moderately sensitive test which is cost effective, acceptable to both clinical staff and parents and meets the criteria for universal screening. Pulse oximetry screening is gaining considerable worldwide support and last year ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.09.013
更新日期:2012-12-01 00:00:00