Abstract：
:Increasing public awareness of the prone sleeping position, maternal smoking and overheating as potentially avoidable risk factors for the sudden infant death syndrome (SIDS) has been accompanied by a dramatic reduction in mortality. The results of two population based studies of SIDS in Avon are compared; the first one occurred before these risk factors were widely known and during the second study there was a gradual increase in publicity. Between the studies the prevalence of prone sleeping in the control populations fell significantly from 60% to 28% and almost all of the reduction in SIDS mortality (3.5 to 1.7 per thousand live births) could be attributed to this change. Other changes were also found: the seasonal pattern of incidence was lost, the proportion of expreterm babies increased and the male predominance was accentuated. The relative importance of smoking and bottle feeding appeared to increase whereas the odds ratios for heavy wrapping and overnight heating were no longer significantly elevated. Small numbers limit the significance of these individual variations but demonstrate that changes are occurring. Local and national public health campaigns have been launched in the UK and abroad to encourage infant care practices that reduce the risk of SIDS. Monitoring the effectiveness of these campaigns is important and may allow new risk factors to be identified which could in turn be targeted in future preventative campaigns. Significant reductions in mortality have followed these initial campaigns but in order to maintain them the message must be regularly renewed using an appropriate approach and effective channels of communication to target high risk families within the community.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Wigfield R,Gilbert R,Fleming PJdoi
10.1016/0378-3782(94)90208-9subject
Has Abstractpub_date
1994-09-15 00:00:00pages
161-4issue
3eissn
0378-3782issn
1872-6232pii
0378-3782(94)90208-9journal_volume
38pub_type
杂志文章abstract：BACKGROUND:Preterm infants have a higher risk of language delay throughout childhood. The ability to integrate audiovisual speech information is associated with language acquisition in term infants; however, the relation is still unclear in preterm infant. AIM AND METHODS:This study longitudinally investigated visual ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.11.001
更新日期：2019-01-01 00:00:00
abstract：BACKGROUND:Acidemia at birth is very common but little is known about its long-term consequences. AIM:To determine if pH at birth is related to established tests of intellectual function. SUBJECTS:School children aged 6-8, for whom obstetric data were available, who had been delivered after labour at term, and had an...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.02.002
更新日期：2008-01-01 00:00:00
abstract：:Magnetic Resonance Imaging is becoming more widely available and increasingly important for imaging the neonatal brain. In newborn infants it poses challenges regarding patient preparation, safety, optimal timing, and sequence optimization. These issues are addressed in this paper and indications for performing neonat...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2008.11.009
更新日期：2009-02-01 00:00:00
abstract：AIM:the effect of selective head cooling on cerebral blood flow (CBF) and cerebral metabolism rate (CMR) was investigated in newborn piglets. METHODS:seven days old newborn piglets were randomly assigned to one of the following three groups: Selective head cooling in normal piglets (n=4), selective head cooling after ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.11.007
更新日期：2011-02-01 00:00:00
abstract：:A comparison has been made of protein accretion and growth in premature infants fed banked drip breast milk (BBM) or a preterm formula (PF). Protein accretion was calculated from the difference between dietary nitrogen intake and output in urine and stools, measured in a nutrient balance study. As expected, only the i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90152-5
更新日期：1985-12-01 00:00:00
abstract：:28 polygraphic recordings were made in normal infants: 20 in full-term newborns and 8 in 2- to 10-wk-old babies. In full-term newborns sighs and apneas (greater than 5 sec) were significantly more numerous in active (REM) sleep, while startles prevailed in quiet (NREM) sleep. The incidence of all these events diminish...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(78)90051-8
更新日期：1978-04-01 00:00:00
abstract：BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.006
更新日期：2014-03-01 00:00:00
abstract：:Newborn infants in critical conditions require a permanent intra-venous line to allow for the administration of fluids, parenteral nutrition and drugs. The use of central venous catheters, however, is associated with an increased risk of infections, leading to prolongation of length of stay and higher hospitalization ...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70017-9
更新日期：2014-03-01 00:00:00
abstract：:The presence of dilated bowel loops antenatally suggests fetal bowel obstruction. Neonatal intestinal obstruction can have different variations in presentation depending on the level and extent of obstruction. Some of these conditions can be diagnosed antenatally. Antenatal detection of surgically correctable anomalie...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2006.02.005
更新日期：2006-05-01 00:00:00
abstract：AIM:Depression during pregnancy is a significant cause of adverse birth outcomes, and its prevalence has increased in recent years. This study aimed to give an updated quantification of the risk of preterm birth (PTB), low birth weight (LBW) and intrauterine growth restriction (IUGR) that is associated with antenatal d...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105243
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Cases suggestive of non-acidemia related cerebral palsy (CP) are likely misdiagnosed as acidemia related CP because of the presence of nonreasuring fetal heart rate (FHR) patterns. AIMS:Our purpose was to compare intrapartum FHR patterns between the cases of neurological damage and the cases without disabil...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.10.007
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Hydatidiform mole is an abnormal pregnancy with over-proliferation of the placenta, which causes the dysfunction of placenta. Although more than 80% of hydatidiform moles are benign with good outcome, hydatidiform moles are associated with developing very early onset preeclampsia. However the association bet...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.02.008
更新日期：2013-08-01 00:00:00
abstract：:It is becoming increasingly apparent that pyridoxine responsive homocystinuria patients are being missed by newborn screening programs. The possibility that screening for homocystine, rather than the methionine, might be more effective was investigated by comparing homocystine and methionine levels of non-responsive p...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01860-9
更新日期：1997-04-25 00:00:00
abstract：:Behavioural state observations were carried out on 12 fetuses which subsequently had birthweights below the 10th percentile. Their gestational ages at the time of study ranged from 32 to 40 weeks. Real-time ultrasound scanning was used to detect fetal body and eye movements, and the fetal heart rate was continuously r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90181-1
更新日期：1985-11-01 00:00:00
abstract：:The Golgi-Cox method was used to study the maturation of the large pyramidal cells of the Vth cortical layer in three groups of adult rats: one subjected to undernutrition during the first month of life, another throughout the first 2 mth of life, and the last one during gestation and the suckling period. The main alt...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(86)90186-6
更新日期：1986-12-01 00:00:00
abstract：:The effect of fetal growth restriction on cardiac size is controversial. It has not been established whether cardiac size of small for gestational age (SGA) fetuses is smaller or larger than appropriate for gestational age (AGA) fetuses. Such controversy may stem from heterogeneity in study population in previous repo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01840-3
更新日期：1997-04-25 00:00:00
abstract：:Vascular tumours (haemangiomas and malformations) are common tumours of infancy and childhood. They represent a group of mostly benign conditions, which present early, can grow rapidly and be symptomatic or disfiguring. There are various management options, with different cosmetic and functional outcomes. Haemangiomas...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.08.017
更新日期：2010-10-01 00:00:00
abstract：AIM:This study examined the rates of follow-up for a cohort of extremely preterm (EP -<28weeks gestation) and/or extremely low birthweight (ELBW -<1000g) children at two years with related perinatal and geographical factors. The secondary aim was to determine the rates of developmental delay and disability. METHODS:A ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.09.012
更新日期：2015-12-01 00:00:00
abstract：:Advances in pharmacology and technology have sharply reduced mortality of extremely preterm infants at the expense of an increasing number of survivors with handicaps and disabilities. The EURONIC study among neonatal intensive care units across Europe demonstrates that treatment of infants born at the limits of viabi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2005.10.004
更新日期：2005-12-01 00:00:00
abstract：:The biochemical, dermatological and neurological motor disorders of biotinidase deficiency (multiple carboxylase deficiency) show a dramatic response to pharmacological doses of biotin. This condition is characterised by the accumulation of biocytin and depletion of biotin. Neuromuscular function returns to normal wit...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90086-6
更新日期：1985-09-01 00:00:00
abstract：:Neonatal sepsis is frequently accompanied by significant and sometimes life-threatening coagulopathy. More complete understanding is needed of the molecular and cellular mechanisms underlying the interaction of the inflammatory and hemostatic systems. Such information may help focus future studies toward novel ways to...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(14)70008-8
更新日期：2014-03-01 00:00:00
abstract：:ROP remains a major cause of childhood blindness worldwide. The smallest, sickest infants develop the most severe forms of zone 1 ROP. Such eyes may not be successfully treated by near confluent laser to the avascular retina (current standard of care). With an understanding of ROP pathogenesis, vascular endothelial gr...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.09.019
更新日期：2012-12-01 00:00:00
abstract：:Cerebral blood flow velocity (CBFV) was measured using Doppler ultrasound on the first day of life in a consecutively admitted cohort of 52 very low birthweight infants. Recordings were made for a period of 1 min. The coefficient of variation for the area under the curve of 20 successive cardiac cycles was calculated,...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01769-0
更新日期：1997-01-03 00:00:00
abstract：:The influence of lung function and reflex activity on the success of patient-triggered ventilation (PTV) has been determined. Lung function was assessed by measurement of compliance using a single breath technique. Reflex activity was assessed by measurement of the strength of Hering Breuer reflex indicated by the deg...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90142-2
更新日期：1994-04-30 00:00:00
abstract：BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.10.003
更新日期：2016-12-01 00:00:00
abstract：:Nutrition has a key role in the modulation of the developing intestine in early infancy, and nutrients are able to modulate several intestinal functions including nutrient absorption, ion transport, cell growth and differentiation, motility and immunomodulation. Such modulation is exerted in part through a direct inte...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2010.01.008
更新日期：2010-07-01 00:00:00
abstract：:The transitional circulation of the preterm infant differs significantly from the term infant. The preterm infant is uniquely at risk of hypotension and low systemic blood flow states due to failure or delay in the normal transitional circulation processes. The maintenance of normal tissue oxygenation requires mainten...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2005.03.006
更新日期：2005-05-01 00:00:00
abstract：:Son preference remains common in countries from East Asia through South Asia to the Middle East and North Africa. Where sex selective technology and abortion are readily available, such as in China, South Korea and India, this has led to a marked excess in male births. Worst excesses are seen in parts of rural China w...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.08.016
更新日期：2011-11-01 00:00:00
abstract：OBJECTIVE:To assess whether patterns of growth trajectory during infancy are associated with intelligence quotient (IQ) scores at 4 years of age in children born small-for-gestational age (SGA). METHODS:Children in the Collaborative Perinatal Project born SGA were eligible for analysis. The primary outcome was the Sta...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.06.002
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND AND AIM:Turner syndrome (TS) patients have an increased risk of weight gain and metabolic syndrome. To date, it is unknown what factors are involved in this metabolic process, even though it is recognized that TS patients are frequently born small-for-gestational age. The aim of this study was to evaluate th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.07.014
更新日期：2012-02-01 00:00:00
