Variability in cerebral blood flow velocity: observations over one minute in preterm babies.

Abstract:

:Cerebral blood flow velocity (CBFV) was measured using Doppler ultrasound on the first day of life in a consecutively admitted cohort of 52 very low birthweight infants. Recordings were made for a period of 1 min. The coefficient of variation for the area under the curve of 20 successive cardiac cycles was calculated, and a 20 cycle moving window then applied to the whole recording. This showed that the coefficient of variation varied widely during 1 min in any individual, the range being from 2% to 28% (median 8%). There was a strong correlation between the variability in CBFV and that in systemic blood pressure (BP). Variability in CBFV was significantly higher in babies with hypotensive episodes (P = 0.026). Babies who died had a higher maximum coefficient of variation than those who survived (P = 0.05), but we were unable to confirm any association with brain injury or patent ductus arteriosus.

journal_name

Early Hum Dev

journal_title

Early human development

authors

Coughtrey H,Rennie JM,Evans DH

doi

10.1016/s0378-3782(96)01769-0

subject

Has Abstract

pub_date

1997-01-03 00:00:00

pages

63-70

issue

1

eissn

0378-3782

issn

1872-6232

pii

S0378378296017690

journal_volume

47

pub_type

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