Abstract：
:Nutrition has a key role in the modulation of the developing intestine in early infancy, and nutrients are able to modulate several intestinal functions including nutrient absorption, ion transport, cell growth and differentiation, motility and immunomodulation. Such modulation is exerted in part through a direct interaction between a single nutrient and the enterocyte. Two functions--ion transport and cell growth--are closely connected and appear to be modulated by nutrients. This is supported by the finding that a single nutrient (e.g. zinc) stimulates ion absorption and also promotes enterocyte growth. Interestingly, intracellular signalling for either effect is similar and involves mitogen-activated protein kinase. Other nutrients also modulate enterocyte function and there is evidence that their effect may depend on their side of action (apical or basolateral) and concentration. Knowledge of the interaction between nutrients and enterocytes may be exploited to obtain clinical effects using nutrition as a long-term treatment for intestinal and non-intestinal conditions.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Buccigrossi V,Giannattasio A,Armellino C,Lo Vecchio A,Caiazzo MA,Guarino Adoi
10.1016/j.earlhumdev.2010.01.008subject
Has Abstractpub_date
2010-07-01 00:00:00pages
55-7eissn
0378-3782issn
1872-6232pii
S0378-3782(10)00010-1journal_volume
86 Suppl 1pub_type
杂志文章,评审abstract：:Abnormal hypertonia of the neck extensor muscles in newborns may be appreciated by observing spontaneous posture, evaluating resistance to repeated passive flexion of the head, and eliciting the head straightening reflexes. This sign correlates well with other signs of insult to the central nervous system. Of 1743 new...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(77)90019-6
更新日期：1977-10-01 00:00:00
abstract：:A new protocol for structured observation of motor performance in infants, SOMP-I, was applied to 72 neonatally healthy fullterm infants at 0, 2, 4, 6 and 10 months of age. It contains 13 items, formed as ascending scales, consisting of detailed descriptions of motor performance in different body positions and body pa...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)01598-J
更新日期：1995-01-30 00:00:00
abstract：BACKGROUND:Respiratory syncytial virus (RSV) is a leading cause of hospitalization for children <1year old and is more severe in premature infants. OBJECTIVE:To assess whether late preterm (LPT) birth is an independent risk factor for RSV hospitalization and more severe RSV disease in children less than 24months old. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2015.06.009
更新日期：2015-09-01 00:00:00
abstract：:Forty-four prenatally depressed women were randomly assigned to peer support or interpersonal psychotherapy groups at 22 weeks gestation. The peer support group participated in a 20-minute group session once per week for 12 weeks, and the interpersonal psychotherapy group met for one hour per week for 12 weeks. Assess...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2013.04.006
更新日期：2013-09-01 00:00:00
abstract：:The autonomy of patients participating in research means that a proper informed consent process must take place. This means that information must be given according to a reasonable person standard implying what legally and ethical a reasonable person participating in the research would want to know. The research must ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.04.025
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Previously, we reported that regular maternal aerobic exercise during pregnancy was associated with lower fetal heart rate (HR) and higher heart rate variability (HRV) at 36weeks gestation. We now report the effect of maternal exercise on infant HR and HRV in subjects who remained active in the study at the ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2013.11.001
更新日期：2014-01-01 00:00:00
abstract：:The fatty acid content of fetal tissues was utilized to estimate essential fatty acid accretion during intrauterine growth. These rates of essential fatty acid accretion were used to predict that 400 mg/kg of body weight for omega-6 fatty acids and 50 mg/kg of body weight for omega-3 fatty acids per day would be used ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(81)90016-5
更新日期：1981-09-01 00:00:00
abstract：PURPOSE:Maternal nutritional status is one of the most important factors of fetal growth and development. Consequently, the currently increasing prevalence of underweight women worldwide has come in the focus of interest of perinatal medicine. The aim of the study was to assess the effect of low pre-pregnancy body mass...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.10.004
更新日期：2013-05-01 00:00:00
abstract：:Twenty-four term infants with disproportionate intrauterine growth retardation (SGA group) and 24 normally grown term infants matched for age, sex, birth rank and social class were followed from birth until 7 years of age. Both groups were free from perinatal complications and chronic diseases. The children in the SGA...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(88)90038-2
更新日期：1988-11-01 00:00:00
abstract：OBJECTIVE:To evaluate the newborn transient evoked otoacoustic emission (TEOAE) hearing screening tests of infants later diagnosed with the sudden infant death syndrome (SIDS). STUDY DESIGN:In a case-controlled study, the newborn TEOAE hearing screens of 31 infants who subsequently died of SIDS were retrospectively co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.06.001
更新日期：2008-04-01 00:00:00
abstract：BACKGROUND:The second-to-fourth digit ratio (2D:4D) reflects prenatal estrogen and testosterone exposure, and is established in utero. Sex steroids are implicated in development and progression of primary brain tumors. AIMS:To investigate whether there is a link between 2D:4D ratio and primary brain tumors, and age at...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.10.003
更新日期：2016-12-01 00:00:00
abstract：:Ninety five placentae from normal term and 'normal' preterm pregnancies have been analysed by morphometry. The growth of the whole placenta, of the microscopic placental constituents and of the villous surface area has been measured in placentae from uncomplicated pregnancies from 10 weeks of gestation to term to prov...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90074-4
更新日期：1984-06-01 00:00:00
abstract：:Mother's own milk is widely recognized as the optimal feeding for term infants, but also provides health benefits that are of vital importance for sick and preterm infants in neonatal intensive care units (NICUs), even though the growth and neurodevelopmental needs of very premature infants are best met by appropriate...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2013.07.008
更新日期：2013-10-01 00:00:00
abstract：:The purpose of this study was to compare two different methods for assessing fetal heart rate (FHR)--fetal eye movement (FEM) synchronization: (1) periods of high (HV) and low (LV) variability in the FHR and the presence (EM) and absence (NEM) of FEM were determined by visual inspection and the degree of association b...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90137-6
更新日期：1992-09-01 00:00:00
abstract：:Altogether 2159 pregnancies among black and white Americans in the Collaborative Perinatal Study and dental casts from the children at the age of 5-12 years were studied to find out the effect of maternal smoking on deciduous tooth crown growth. Minor crown size reduction (2-3%) in some dimensions was found in childre...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90086-v
更新日期：1992-08-01 00:00:00
abstract：:A new protocol for Structured Observation of Motor Performance in Infants, SOMP-I, designed to describe both progress and quality of motor performance, was evaluated concerning its ability to describe and to discriminate between the motor performance observed in different groups of infants. Sixty-eight infants born at...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(95)01678-3
更新日期：1995-11-24 00:00:00
abstract：AIM:The effects of intestinal bifidobacteria on the development of immunity in early life were explored. METHODS:Neonatal SD rats born and housed under strict barrier systems were fed from birth with sufficient antibiotics (bifidobacteria minimisation group) or supplemented daily with 1x10(10) colony-forming units of ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.01.002
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND:Fluconazole prophylaxis has demonstrated efficacy in single and multicenter randomized controlled trials without side effects or emergence of resistance. Additional evidence based on incidence of invasive Candida infections, multicenter data, resistance, and safety is desired. METHODS:We conducted a case-co...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/S0378-3782(14)70026-X
更新日期：2014-03-01 00:00:00
abstract：:Maturation of spontaneous fetal body and breathing movements of 24- to 33-week-old fetuses in 168 pregnancies threatening to deliver prematurely were examined on the basis of newborn outcome (premature compromised, premature healthy, term healthy). Maturation of fetuses in 60 low-risk pregnancies delivering as healthy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(99)00007-9
更新日期：1999-05-01 00:00:00
abstract：BACKGROUND:Few studies describe in detail the pregnancy and early development of infants with Prader-Willi syndrome (PWS). However, variations at these early stages may partially account for differences in the later phenotype. A recent paper described an abnormally high number of problems in pregnancy and early infancy...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.08.007
更新日期：2008-05-01 00:00:00
abstract：:In the infant, sucking behaviour is one of the first coordinated muscular activities. It is under the control of the brainstem. In utero sucking is observed from 13 weeks' gestation. The healthy full-term newborn infant has a very stable rhythm of alternating bursts of sucking with pauses in between. The non-nutritive...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(00)00091-8
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:An increased risk of major congenital abnormalities after IVF and ICSI has been described, but underlying mechanisms are unclear. This study evaluates the effects of ovarian hyperstimulation, the in vitro procedure and time to pregnancy (TTP) - as proxy for the severity of subfertility - on the prevalence of...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.06.002
更新日期：2012-10-01 00:00:00
abstract：:Whether preeclampsia affects the fetal hematologic system still remains a controversial issue. The purpose of this series was to examine the hypothesis that preeclampsia may or may not cause adverse effects on fetal hemogram, including erythrocytes, leukocytes, and platelets. In addition, no one, to date, has reported...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(94)90150-3
更新日期：1994-05-01 00:00:00
abstract：:A review of the conundrum called mild hypoxic-ischemic encephalopathy (HIE) is provided. During the past decades, the definition of HIE has evolved to accommodate the short window of time required for the initiation of therapeutic hypothermia. Also, neurological evaluations have changed with the use of simpler staging...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2018.02.008
更新日期：2018-05-01 00:00:00
abstract：:In 1% of monozygotic twin pregnancies, one fetus is without a heart; blood circulation is maintained by an accompanying "pump" twin. Such an acardiac condition is usually diagnosed on the basis of further malformations visible by ultrasonography. We describe a monoamniotic twin pregnancy with early growth reduction in...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00011-5
更新日期：1998-08-28 00:00:00
abstract：:We measured plasma and erythrocyte vitamin E (VE) and plasma vitamin A (VA) profiles in 48 full-term and 8 preterm pairs of neonates and their mothers at birth and we determined whether there is any relationship between maternal and umbilical cord for the nutrients measured. At the same time, we assessed the influence...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00070-x
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND:Hospitalized infants requiring cardiopulmonary resuscitation (CPR) represent a high-risk group. Recent data on risk factors for mortality following CPR in this population are lacking. AIMS:We hypothesized that infant demographic characteristics, diagnoses, and levels of cardiopulmonary support at the time o...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.03.015
更新日期：2016-10-01 00:00:00
abstract：:Whenever possible, oral feeding is the preferred method in neonatal feeding. However, many premature infants are unable to suck and swallow effectively; in these cases alternative methods of nutrient delivery must be used. We briefly review the different feeding methods used in neonatal units, with particular attentio...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/S0378-3782(12)70011-7
更新日期：2012-05-01 00:00:00
abstract：:In planning enteral feeding in the preterm infant, decisions need to be made regarding the feeding schedule, choice of milk, and the route of administration. Feeds should be commenced within a week after birth beginning with subnutritional quantities. Preterm human milk from the infant's own mother is the milk of choi...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/s0378-3782(99)00047-x
更新日期：1999-12-01 00:00:00
abstract：BACKGROUND:Parent perception of child vulnerability (PPCV) and parent overprotection (POP) are believed to have serious implications for age appropriate cognitive and psychosocial development in very low birth weight preterm children. AIM:With recent concerns about suboptimal developmental outcomes in late-preterm chi...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.07.005
更新日期：2010-09-01 00:00:00
