Abstract:
:The effect of fetal growth restriction on cardiac size is controversial. It has not been established whether cardiac size of small for gestational age (SGA) fetuses is smaller or larger than appropriate for gestational age (AGA) fetuses. Such controversy may stem from heterogeneity in study population in previous reports. Both fetal hypoxemia and increased impedance to flow in fetoplacental vessels, two findings often encountered in severe fetal growth restriction, may lead to cardiomegaly. Therefore we have measured cardiac dimensions and cardiothoracic indices in a homogeneous group of SGA fetuses without ultrasonographic or Doppler evidence of fetal distress or increased umbilical artery flow impedance (n = 10). This group was compared with AGA fetuses matched for sex and estimated fetal weight (n = 20). No differences were observed between the two groups in cardiac and chest measurements and indices. Heart circumference and area significantly correlated with fetal weight, both among AGA (r = 0.88 for both; P < 0.0001), as well as SGA fetuses (r = 0.89 and 0.88, respectively; P = 0.0006 and 0.0008).
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Miyague NI,Ghidini Adoi
10.1016/s0378-3782(96)01840-3subject
Has Abstractpub_date
1997-04-25 00:00:00pages
93-8issue
1-2eissn
0378-3782issn
1872-6232pii
S0378-3782(96)01840-3journal_volume
48pub_type
杂志文章abstract:UNLABELLED:The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1.5 mg/kg, 6 hourly] or placebo was given first over 7 days in a double blind randomized crossover study of 21 preterm infants with feed intolerance. Median [r...
journal_title:Early human development
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0378-3782(01)00191-8
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:There is concern that exposure of preterm infants to noxious insults over a prolonged period may have long term effects on their developing nervous system. AIMS:To investigate medium and long term effects of heel pricks in infants over the first year of life. STUDY DESIGN:Study 1-a longitudinal study, 2 da...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2007.09.018
更新日期:2008-06-01 00:00:00
abstract::This study examined the oral sensitivity and feeding skills of low-risk pre-term infants at 11-17 months corrected age. Twenty pre-term infants (PT) born between 32 and 37 weeks at birth without any medical comorbidities were assessed. All of this PT group received supplemental nasogastric (NG) tube feeds during their...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.10.001
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:A reliable and valid assessing tool to detect the problem before the child becomes deviant is very important. AIM:This study aimed to further test the reliability and validity of developmental screening instrument for follow-up of thirty-six months children in Taiwan. Also, the stability and changes in the ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2009.12.004
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Angiogenesis, a critical process for growth and development is altered in intrauterine growth restriction (IUGR). Vascular endothelial growth factor (VEGF) and its receptors VEGFR-1, soluble (s) VEGFR-1 and VEGFR-2 represent a regulatory system, essential for both physiological and pathological angiogenesis....
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2005.09.010
更新日期:2006-04-01 00:00:00
abstract:BACKGROUND:The kidney is one organ which presents distinct morphology depending on GA; the classic references for kidney measurements were established several years ago and it is not certain if they are still accurate. AIM:To evaluate the renal maturity using a computer-assisted morphometry in autopsied fetuses within...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2006.01.013
更新日期:2006-11-01 00:00:00
abstract::Human and animal studies demonstrate that uteroplacental insufficiency and subsequent intrauterine growth retardation (IUGR) decrease intestinal growth and lead to both an increased incidence of feeding intolerance and necrotizing enterocolitis. Our objective was to determine the effects of uteroplacental insufficienc...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.04.015
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Gastroschisis and omphalocele are the most common anterior abdominal wall defects affecting infants. There are few large cohort studies describing the frequency of associated anomalies in infants with these 2 conditions. We describe associated anomalies and outcomes in infants with these defects using a larg...
journal_title:Early human development
pub_type: 杂志文章,多中心研究
doi:10.1016/j.earlhumdev.2014.05.006
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Prior studies have shown that children with congenital hearing loss have increased rates of behavior disorders. Child hearing loss has also been reported to be associated with increased maternal stress. Little is known about the behavior or the predictors of behavioral outcomes of children with hearing loss ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.06.006
更新日期:2011-12-01 00:00:00
abstract::Cerebral blood flow velocity (CBFV) was measured using Doppler ultrasound on the first day of life in a consecutively admitted cohort of 52 very low birthweight infants. Recordings were made for a period of 1 min. The coefficient of variation for the area under the curve of 20 successive cardiac cycles was calculated,...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(96)01769-0
更新日期:1997-01-03 00:00:00
abstract::Apnea of prematurity and gastroesophageal reflux (GER) are both common occurrences in preterm infants and widely perceived to be causally related. We seek in this review to provide a potential guideline for neonatal GER non-pharmacologic and pharmacologic therapy. Available physiologic data suggest that when there is ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/S0378-3782(13)70005-7
更新日期:2013-06-01 00:00:00
abstract::Cord blood thyroxine (T4) concentrations were measured in 4,068 infants from 28 wk gestation to term. Each chart was reviewed for the following factors: delivery by cesarean section, prolonged rupture of membranes, neonatal asphyxia, meconium-stained amniotic fluid, maternal diabetes mellitus and twinning. Each neonat...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(78)90031-2
更新日期:1978-09-01 00:00:00
abstract:BACKGROUND:Retinopathy of prematurity (ROP) is often associated with visual impairment and multiple developmental disabilities. AIMS:As most of the previous studies include infants with brain lesions, that can determine visual impairment per se, a cohort of low neurological risk preterm infants without ROP and with va...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105134
更新日期:2020-09-01 00:00:00
abstract::One hundred consecutive cranial computed tomographic scans were reviewed in children aged 0-2 years, presenting to the Royal Belfast Hospital for Sick Children. The mean age at scanning was 8.3 months and 73% of the scans were abnormal. The majority of scans were performed electively (78%). The commonest indication fo...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(91)90011-q
更新日期:1991-08-01 00:00:00
abstract:AIMS:To study longitudinal growth pattern of head circumference of full-term symmetric and asymmetric small for gestational age (SGA) infants of the two sexes during first year of life. STUDY DESIGN:Mixed-longitudinal growth research design. SUBJECTS:Head circumference amongst full-term 100 symmetric, 100 asymmetric ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2011.11.007
更新日期:2012-07-01 00:00:00
abstract::Nearly 10% of premature infants are born very preterm at 32weeks gestational age or less in the United States. Up to 35% of these very preterm survivors are at risk for cognitive and behavioral deficits. Yet accurate diagnosis of such deficits cannot be made until early childhood. Resting-state fMRI provides noninvasi...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.06.002
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The parental bond is characterized by the perception of care and protection received by parental figures throughout human development. During the gestational period, the intensity in which the woman manifests behaviors and feelings for the fetus was denominated maternal-fetal attachment (MFA). In this perspe...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2021.105310
更新日期:2021-01-22 00:00:00
abstract::In a prospective clinical study from an unselected, area-based population, the influence on birthweight for gestational age of different factors was studied, with special respect to 15 risk factors for intrauterine growth retardation (IUGR) recognizable in early pregnancy. In the multiple regression analyses performed...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90110-5
更新日期:1984-09-01 00:00:00
abstract::Newborn infants, especially preterm infants, have an immature immune system, which is not capable to actively protect against vaccine-preventable infections. Therefore, the newborn is dependent on transplacental transport of Immunoglobulin G (IgG), an active, FcRn receptor mediated process. Fetal IgG rises from approx...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2010.11.003
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM:To estimate the risk of attention problems at age 10years in children born very preterm to overweight ...
journal_title:Early human development
pub_type: 杂志文章,多中心研究
doi:10.1016/j.earlhumdev.2017.08.002
更新日期:2017-12-01 00:00:00
abstract::The prone sleeping position has been identified in world-wide epidemiological studies as a major risk factor for sudden infant death syndrome (SIDS). Public awareness campaigns throughout the western world have led to an over 50% reduction in postneonatal mortality and frequency of SIDS. This reduction in mortality ha...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(02)00025-7
更新日期:2002-10-01 00:00:00
abstract::This year is the 20th anniversary of the first successful trial of exogenous surfactant for respiratory distress syndrome in the newborn and it is perhaps a good time to review recent advances in basic science and clinical practice as they relate to surfactant therapy. ...
journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/s0378-3782(00)00122-5
更新日期:2001-03-01 00:00:00
abstract::Eleven healthy, full-term babies were studied on the second day (d2) after birth and again 4 weeks (w4) later. The babies lived in natural lighting conditions and were fed every 4 h. Blood pressure, heart rate, skin (abdomen) and rectal temperatures were measured at 10-min intervals for 24 h. Behavioural states (deep ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(94)90039-6
更新日期:1994-02-01 00:00:00
abstract::The mediating effect of maternal self-efficacy in the association between locus of control and anxiety, among mothers of hospitalized babies in the Neonatal Intensive Care Unit (NICU) was examined. Findings confirmed partial mediation effect suggesting that professionals can contribute to the reduction of levels of an...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105284
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Human milk contains a range of host defence proteins that appear to contribute to health and wellbeing, but their variability in abundance among individuals has not been very well characterised. Milk from mothers of premature infants has altered composition, but the effect of gestation length on the host-def...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.11.006
更新日期:2015-01-01 00:00:00
abstract::Urinary epidermal growth factor (EGF) excretion was studied serially in 36 newborn infants, from 26 to 40 weeks gestation, from birth to three months of age. All infants excreted EGF from birth. Excretion was significantly higher in term infants than in preterm infants at birth; in term infants excretion rose steadily...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(86)90190-8
更新日期:1986-12-01 00:00:00
abstract::We describe the managment of 2 sets of pre-term quadruplets born to 2 women pregnant concurrently following the induction of ovulation with gonadotrophin. Careful antenatal planning was necessary to provide for each of the 8 pre-term infants a standard of neonatal medical and nursing care comparable to that normally a...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(77)90028-7
更新日期:1977-10-01 00:00:00
abstract:BACKGROUND:Non-nutritive suck (NNS) is one piece of the complex oral feeding process, yet there is paucity on how it develops throughout the first year of life. AIMS:To determine changes in infant NNS between 3 and 12 months of age. STUDY DESIGN:Twenty-six full-term infants (65% male) completed this study. All infant...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105141
更新日期:2020-10-01 00:00:00
abstract:BACKGROUND:Pregnancy and delivery are complex processes, and isolated obstetric complications rare and often accompanied or followed by a number of others. AIMS:To study the relationship between the overall obstetric situation (as opposed to single obstetric risk factors) and emotional and substance use disorders in y...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2004.04.016
更新日期:2004-11-01 00:00:00
abstract::The fatty acid content of fetal tissues was utilized to estimate essential fatty acid accretion during intrauterine growth. These rates of essential fatty acid accretion were used to predict that 400 mg/kg of body weight for omega-6 fatty acids and 50 mg/kg of body weight for omega-3 fatty acids per day would be used ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(81)90016-5
更新日期:1981-09-01 00:00:00