Abstract:
UNLABELLED:The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1.5 mg/kg, 6 hourly] or placebo was given first over 7 days in a double blind randomized crossover study of 21 preterm infants with feed intolerance. Median [range] birth weight was 1420 [690, 2200] g and postconceptual age 32. 5 [20, 36.4] weeks. WGTT was assessed on day 3 of each treatment, by timing the transit of carmine red through the gut. Treatments were compared using Student's paired t test. RESULTS:WGTT was significantly shorter following EM treatment as compared to placebo: mean [SD] 10.16 [4.6] h vs. 15. 9 [7.2] h, p<0.01. CONCLUSION:Oral low-dose EM significantly shortens WGTT of feed-intolerant preterm infants.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Costalos C,Gavrili V,Skouteri V,Gounaris Adoi
10.1016/s0378-3782(01)00191-8keywords:
subject
Has Abstractpub_date
2001-12-01 00:00:00pages
91-6issue
2eissn
0378-3782issn
1872-6232pii
S0378378201001918journal_volume
65pub_type
临床试验,杂志文章,随机对照试验abstract::Intrauterine growth restriction (IUGR) is associated with altered lung development in human and rat. The transcription factor PPARγ, is thought to contribute to lung development. PPARγ is activated by docosahexanoic acid (DHA). One contribution of PPARγ to lung development may be its direct regulation of chromatin mod...
journal_title:Early human development
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doi:10.1016/j.earlhumdev.2010.08.026
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abstract::CMV is the most common congenital infection in newborns worldwide. Congenital CMV causes sensorineural hearing loss in a significant proportion of infected newborns, while the majority of newborns are asymptomatic. In the last three years there have been significant advances in the diagnosis and treatment of congenita...
journal_title:Early human development
pub_type: 杂志文章,实务指引
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abstract::Soluble fibrinogen--fibrin complex levels were found to be significantly higher in plasma samples from pregnant women with babies suffering from intrauterine growth retardation, when compared with levels found in normal pregnancy. As soluble fibrinogen--fibrin complexes are formed following activation of the coagulati...
journal_title:Early human development
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journal_title:Early human development
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journal_title:Early human development
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journal_title:Early human development
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journal_title:Early human development
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journal_title:Early human development
pub_type: 杂志文章
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journal_title:Early human development
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journal_title:Early human development
pub_type: 杂志文章
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2003.09.002
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.01.012
更新日期:2012-08-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(89)90099-6
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.10.013
更新日期:2015-12-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(00)00079-7
更新日期:2000-06-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2007.09.018
更新日期:2008-06-01 00:00:00
abstract:BACKGROUND:Natural cell death due to apoptotic mechanisms has been described in various species. Relatively few studies examined this process in humans. AIM:To investigate the distribution of apoptosis in fetal brain tissue. DESIGN:We examined apoptosis in the frontal region of human fetal brain by the TUNEL method i...
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pub_type: 杂志文章
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更新日期:2003-02-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.08.015
更新日期:2014-12-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
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更新日期:2009-10-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2019.07.008
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Previously, we reported that regular maternal aerobic exercise during pregnancy was associated with lower fetal heart rate (HR) and higher heart rate variability (HRV) at 36weeks gestation. We now report the effect of maternal exercise on infant HR and HRV in subjects who remained active in the study at the ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2013.11.001
更新日期:2014-01-01 00:00:00
abstract::805 normal-for-age human embryos and fetuses were used to study early prenatal fat development. The investigation included observations on stages of fat morphogenesis at the light microscopic level and computerized image analyses of fat lobule size and number. The buccal fat pad was selected as a model system for the ...
journal_title:Early human development
pub_type: 杂志文章
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journal_title:Early human development
pub_type: 杂志文章
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更新日期:2016-10-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2016.09.015
更新日期:2016-12-01 00:00:00
abstract::Fetal bladder volume and hourly fetal urine production (HFUPR) is calculated on the assumption that the fetal bladder is ellipsoid in shape. A recent validation study demonstrated a progressive overestimation at increasing bladder volumes. This may be due to changes in shape of the fetal bladder at increasing volumes....
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00049-2
更新日期:1998-02-27 00:00:00