Abstract：
:gamma-Aminobutyric acid (GABA) concentrations in cerebrospinal fluid (CSF) were measured in 20 neonates with various gestational and postnatal ages. These concentrations varied between 9 and 45 nmol/ml which is approximately 20-100 times the concentrations found in adults. CSF GABA concentrations tended to decrease with advancing gestational age. No apparent alterations were noted with increasing postnatal age (until 6 weeks of age). Asphyxia but not neonatal sepsis was accompanied by an increase in CSF GABA concentrations compared to respective controls.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Hedner T,Iversen K,Lundborg Pdoi
10.1016/0378-3782(82)90007-xsubject
Has Abstractpub_date
1982-10-01 00:00:00pages
53-8issue
1eissn
0378-3782issn
1872-6232pii
0378-3782(82)90007-Xjournal_volume
7pub_type
杂志文章abstract：:Vascular tumours (haemangiomas and malformations) are common tumours of infancy and childhood. They represent a group of mostly benign conditions, which present early, can grow rapidly and be symptomatic or disfiguring. There are various management options, with different cosmetic and functional outcomes. Haemangiomas...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.08.017
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Corrected age is typically applied when assessing the development of children born <32 weeks of gestation. There is no consensus as to whether corrected age should be applied when assessing children born late/moderately preterm (LMPT; 32-36 weeks of gestation). AIMS:This study explored the impact of correct...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2016.01.002
更新日期：2016-03-01 00:00:00
abstract：:The introduction of exchange transfusion made it possible to prevent severe hyperbilirubinemia and kernicterus, but kernicterus has never completely disappeared and it is still occurring in North America and, more frequently in Western Europe and the developing world. I discuss the epidemiology and major causes of sev...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2009.09.003
更新日期：2009-11-01 00:00:00
abstract：:The effect of type-I diabetes on the quality of general movements (GMs) was studied longitudinally in 12 human fetuses. GMs were analysed at two-weekly intervals from 16 weeks until delivery. A pregnancy optimality-score and a diabetes optimality-score were used to cover the course of the pregnancy and delivery and th...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(97)00089-3
更新日期：1997-11-24 00:00:00
abstract：BACKGROUND AND AIMS:Postural control differs between infants born preterm and full term at 1-3weeks of age. It is unclear if differences persist or alter the development of early behaviors. The aim of this longitudinal study was to compare changes in postural control variability during development of head control and r...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.01.006
更新日期：2014-03-01 00:00:00
abstract：BACKGROUND:The long-term effect of early intervention in infants at risk for developmental disorders is unclear. The VIP project (n=46, originally) evaluated by means of a randomised controlled trial the effect of the family centred early intervention programme COPCA (Coping with and Caring for infants with special nee...
journal_title：Early human development
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.earlhumdev.2017.02.002
更新日期：2017-01-01 00:00:00
abstract：:The relationship between cyclic 3',5'-adenosine monophosphate (cAMP) excretion and creatinine clearance, urinary phosphate excretion, and urinary osmolarity was studied under basal conditions in 29 babies of 28-40 weeks gestation, during the first few days of life. Urinary cAMP excretion was directly related to creati...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90112-9
更新日期：1984-09-01 00:00:00
abstract：:The mediating effect of maternal self-efficacy in the association between locus of control and anxiety, among mothers of hospitalized babies in the Neonatal Intensive Care Unit (NICU) was examined. Findings confirmed partial mediation effect suggesting that professionals can contribute to the reduction of levels of an...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105284
更新日期：2021-01-01 00:00:00
abstract：AIM:The benefit of anti-reflux surgery for gastro-oesophageal reflux (GOR) in early infancy is uncertain. The aim of this study was to assess the value of Nissen fundoplication in a group of infants with severe GOR. METHODS:10 infants underwent Nissen fundoplication for gastro-oesophageal reflux following a failure of...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2003.09.002
更新日期：2003-12-01 00:00:00
abstract：:To determine the assessments before discharge from the intensive care unit, that will predict outcome most accurately, a prospective longitudinal study in a cohort of 79 high risk VLBW children was conducted from birth to 3.6 years of age. Birthweight, gestational age, obstetrical and neonatal optimality, neonatal neu...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(92)90040-n
更新日期：1992-12-01 00:00:00
abstract：:198 infants were followed up from birth until 4 1/2-5 years to observe the development of eczema and asthma and its relation to infant feeding. Findings here refer only to eczema. Comparison between those initially breastfed, regardless of duration, and those fed on cows milk preparations showed little difference in t...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(84)90039-2
更新日期：1984-04-01 00:00:00
abstract：BACKGROUND:Infants whose mothers had low serum pregnancy-associated plasma protein-A (PAPP-A) in the first trimester were observed to have intrauterine growth retardation. AIM:Suggesting that PAPP-A plays an important role in the availability and activity of insulin-like growth factors (IGFs), which affect growth, we ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2006.10.005
更新日期：2007-07-01 00:00:00
abstract：UNLABELLED:The aim of the study was to determine the effect of a low oral dose of erythromycin on whole gastrointestinal transit time [WGTT]. Erythromycin [EM] [1.5 mg/kg, 6 hourly] or placebo was given first over 7 days in a double blind randomized crossover study of 21 preterm infants with feed intolerance. Median [r...
journal_title：Early human development
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0378-3782(01)00191-8
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Human milk contains a range of host defence proteins that appear to contribute to health and wellbeing, but their variability in abundance among individuals has not been very well characterised. Milk from mothers of premature infants has altered composition, but the effect of gestation length on the host-def...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2014.11.006
更新日期：2015-01-01 00:00:00
abstract：:We measured plasma and erythrocyte vitamin E (VE) and plasma vitamin A (VA) profiles in 48 full-term and 8 preterm pairs of neonates and their mothers at birth and we determined whether there is any relationship between maternal and umbilical cord for the nutrients measured. At the same time, we assessed the influence...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(98)00070-x
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND:Pregnancy and delivery are complex processes, and isolated obstetric complications rare and often accompanied or followed by a number of others. AIMS:To study the relationship between the overall obstetric situation (as opposed to single obstetric risk factors) and emotional and substance use disorders in y...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2004.04.016
更新日期：2004-11-01 00:00:00
abstract：BACKGROUND:Selective serotonin reuptake inhibitors (SSRIs) are prescribed in 2-8% during pregnancy. Whether prenatal exposure to SSRIs has long-term effects on the children's development is unknown. AIM:The aim of this study was to determine the effect of prenatal exposure to SSRIs on children's cognitive, motor, and ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2020.105075
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Placental pathology is associated with long-term neurological morbidity. Little is known about the association of placental pathology and illness severity directly after birth in preterm infants. OBJECTIVE:To determine the association between placental pathology and illness severity in preterm infants durin...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2011.01.040
更新日期：2011-04-01 00:00:00
abstract：BACKGROUND:The entorhinal cortex serves as an important gateway between the cerebral cortex and the hippocampus by receiving afferent information from limbic, modality sensory-specific, and multimodal association fibers from all the brain lobes. AIM:To investigate whether thinning of entorhinal cortex is associated wi...
journal_title：Early human development
pub_type： 临床试验,杂志文章
doi：10.1016/j.earlhumdev.2011.07.017
更新日期：2012-02-01 00:00:00
abstract：:We assessed the relation of perinatal factors to severe hypothyroxinemia of prematurity, defined as thyroxine value more than 2.6 standard deviations below the mean for newborns. The 365 survivors of birth before 32 weeks gestation were enrolled in a population-based study of the correlates of neonatal brain injury. I...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01843-9
更新日期：1997-01-20 00:00:00
abstract：:Pulse oximetry screening for critical congenital heart defects (CCHDs) is a highly specific, moderately sensitive test which is cost effective, acceptable to both clinical staff and parents and meets the criteria for universal screening. Pulse oximetry screening is gaining considerable worldwide support and last year ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2012.09.013
更新日期：2012-12-01 00:00:00
abstract：:The presence of dilated bowel loops antenatally suggests fetal bowel obstruction. Neonatal intestinal obstruction can have different variations in presentation depending on the level and extent of obstruction. Some of these conditions can be diagnosed antenatally. Antenatal detection of surgically correctable anomalie...
journal_title：Early human development
pub_type： 杂志文章,评审
doi：10.1016/j.earlhumdev.2006.02.005
更新日期：2006-05-01 00:00:00
abstract：AIM:the effect of selective head cooling on cerebral blood flow (CBF) and cerebral metabolism rate (CMR) was investigated in newborn piglets. METHODS:seven days old newborn piglets were randomly assigned to one of the following three groups: Selective head cooling in normal piglets (n=4), selective head cooling after ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2010.11.007
更新日期：2011-02-01 00:00:00
abstract：AIMS:1. To determine the survival and morbidity of infants at discharge with a birthweight of less than 1500 g in the geographically defined population of East Anglia. 2. To demonstrate a cost-effective method of regional data collection. 3. To determine whether there were any changes in the demand for neonatal care. ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2005.10.019
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Fetal cells exfoliate in the uterine cavity during early pregnancy and are a potential source of material for NIPD. AIMS:This study was designed to test the hypothesis that fetal cells obtained from the uterine cervix during the first trimester of pregnancy could be utilized for prenatal diagnosis of chromo...
journal_title：Early human development
pub_type： 临床试验,杂志文章
doi：10.1016/j.earlhumdev.2010.04.005
更新日期：2010-05-01 00:00:00
abstract：:The effect of fetal growth restriction on cardiac size is controversial. It has not been established whether cardiac size of small for gestational age (SGA) fetuses is smaller or larger than appropriate for gestational age (AGA) fetuses. Such controversy may stem from heterogeneity in study population in previous repo...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/s0378-3782(96)01840-3
更新日期：1997-04-25 00:00:00
abstract：OBJECTIVE:To evaluate the newborn transient evoked otoacoustic emission (TEOAE) hearing screening tests of infants later diagnosed with the sudden infant death syndrome (SIDS). STUDY DESIGN:In a case-controlled study, the newborn TEOAE hearing screens of 31 infants who subsequently died of SIDS were retrospectively co...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2007.06.001
更新日期：2008-04-01 00:00:00
abstract：:The autonomy of patients participating in research means that a proper informed consent process must take place. This means that information must be given according to a reasonable person standard implying what legally and ethical a reasonable person participating in the research would want to know. The research must ...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2018.04.025
更新日期：2018-09-01 00:00:00
abstract：:A comparison has been made of protein accretion and growth in premature infants fed banked drip breast milk (BBM) or a preterm formula (PF). Protein accretion was calculated from the difference between dietary nitrogen intake and output in urine and stools, measured in a nutrient balance study. As expected, only the i...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/0378-3782(85)90152-5
更新日期：1985-12-01 00:00:00
abstract：BACKGROUND:Among preterm infants, high concentrations of inflammatory mediators in cerebrospinal fluid (CSF) are associated with poor outcome. Previous studies have not indicated whether CSF concentrations of inflammatory mediators are associated with important confounders such as gestational age. AIMS:To examine asso...
journal_title：Early human development
pub_type： 杂志文章
doi：10.1016/j.earlhumdev.2008.10.011
更新日期：2009-04-01 00:00:00
