Abstract:
BACKGROUND:Placental pathology is associated with long-term neurological morbidity. Little is known about the association of placental pathology and illness severity directly after birth in preterm infants. OBJECTIVE:To determine the association between placental pathology and illness severity in preterm infants during the first 24 h after birth. STUDY DESIGN:Placentas of 40 preterm infants, born after singleton pregnancies (gestational age 25.4-31.7 weeks, birth weight 560-2250 g) were assessed for histopathology. Illness severity was measured using the Score of Neonatal Acute Physiology Perinatal Extension (SNAPPE). A high SNAPPE reflects high illness severity. RESULTS:Examination of the 40 placentas revealed: pathology consistent with maternal vascular underperfusion (MVU) (n=24), ascending intrauterine infection (AIUI) (n=17), villitis of unknown aetiology (VUE) (n=6), foetal thrombotic vasculopathy (FTV) (n=6), elevated nucleated red blood cells (NRBCs) (n=6), and chronic deciduitis (n=10). SNAPPE ranged from 1 to 53 (median 10). Infants with elevated NRBCs had a higher SNAPPE than infants without elevated NRBCs (median 30 vs. 10, p=0.014). The same was found for the presence of FTV (median 30 vs. 10, p=0.019). No relation existed between SNAPPE and the other placental pathologies. CONCLUSIONS:Elevated NRBCs and FTV were associated with higher illness severity during the first 24 h after birth in preterm infants. Ascending intrauterine infection was not associated with high illness severity.
journal_name
Early Hum Devjournal_title
Early human developmentauthors
Roescher AM,Hitzert MM,Timmer A,Verhagen EA,Erwich JJ,Bos AFdoi
10.1016/j.earlhumdev.2011.01.040subject
Has Abstractpub_date
2011-04-01 00:00:00pages
315-9issue
4eissn
0378-3782issn
1872-6232pii
S0378-3782(11)00077-6journal_volume
87pub_type
杂志文章abstract:AIM:To compare the order and age of emergence of rolling prone to supine and supine to prone before the introduction of back to sleep guidelines and 20 years after their introduction. METHODS:The original normative data for the Alberta Infant Motor Scale (AIMS) were collected just prior to the introduction of back to ...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2012.10.009
更新日期:2013-05-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2019-09-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90152-5
更新日期:1985-12-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章,实务指引
doi:10.1016/j.earlhumdev.2020.104992
更新日期:2020-05-01 00:00:00
abstract:BACKGROUND:Despite its prevalence and potential maternal and neonatal implications, the literature on the thickness levels of meconium stained amniotic fluid (MSAF) and its impact on neonatal outcomes is relatively outdated and relies on relatively small sample sizes. AIMS:To study if different thickness levels of MSA...
journal_title:Early human development
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doi:10.1016/j.earlhumdev.2020.104953
更新日期:2020-03-01 00:00:00
abstract::Candidal chorioamnionitis is an uncommon and apparently rather indolent intrauterine infection in which the fetus is able to marshal some of the immunological forces at its disposal against an easily visualized antigen impinging on lung mucosal surfaces. In a retrospective histological study of one of the largest repo...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(85)90113-6
更新日期:1985-05-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90132-z
更新日期:1992-06-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
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journal_title:Early human development
pub_type: 杂志文章
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(92)90172-d
更新日期:1992-03-01 00:00:00
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journal_title:Early human development
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doi:10.1016/j.earlhumdev.2020.105221
更新日期:2020-12-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105134
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abstract:BACKGROUND:It remains unclear whether performing amniocentesis to detect intra-amniotic infection is useful for improving neonatal outcomes. AIMS:To determine the efficacy of amniocentesis on the neonatal outcomes in women exhibiting threatened preterm labor and intact membranes. STUDY DESIGN:Retrospective cohort stu...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.03.006
更新日期:2015-05-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2014.11.006
更新日期:2015-01-01 00:00:00
abstract::The relationship between the traction forces used in 53 clinically indicated vacuum extractions and the incidence and degree of retinal hemorrhages observed in the neonates within 24 hours after birth was examined. A Vacuum Extractor Recorder (Type SF 30, Knick), was used to measure the traction force necessary for de...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(88)90107-7
更新日期:1988-03-01 00:00:00
abstract::28 polygraphic recordings were made in normal infants: 20 in full-term newborns and 8 in 2- to 10-wk-old babies. In full-term newborns sighs and apneas (greater than 5 sec) were significantly more numerous in active (REM) sleep, while startles prevailed in quiet (NREM) sleep. The incidence of all these events diminish...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(78)90051-8
更新日期:1978-04-01 00:00:00
abstract::A new protocol for Structured Observation of Motor Performance in Infants, SOMP-I, designed to describe both progress and quality of motor performance, was evaluated concerning its ability to describe and to discriminate between the motor performance observed in different groups of infants. Sixty-eight infants born at...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(95)01678-3
更新日期:1995-11-24 00:00:00
abstract::Ultrastructural and immunohistochemical studies were made of the testicular interstitial tissue from eight human fetuses of 15 to 27 weeks gestation. Three cell types developed in mesenchymal cells: Leydig cells and peritubular cells, as already reported, and cells of the mononuclear phagocyte system (MPS), which are ...
journal_title:Early human development
pub_type: 杂志文章
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更新日期:1989-09-01 00:00:00
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pub_type: 杂志文章
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更新日期:2003-05-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
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journal_title:Early human development
pub_type: 杂志文章,评审
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更新日期:1998-12-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.05.009
更新日期:2015-09-01 00:00:00
abstract::The effect of type-I diabetes on the quality of general movements (GMs) was studied longitudinally in 12 human fetuses. GMs were analysed at two-weekly intervals from 16 weeks until delivery. A pregnancy optimality-score and a diabetes optimality-score were used to cover the course of the pregnancy and delivery and th...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/s0378-3782(97)00089-3
更新日期:1997-11-24 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(84)90117-8
更新日期:1984-09-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2015.08.015
更新日期:2015-12-01 00:00:00
abstract::The mediating effect of maternal self-efficacy in the association between locus of control and anxiety, among mothers of hospitalized babies in the Neonatal Intensive Care Unit (NICU) was examined. Findings confirmed partial mediation effect suggesting that professionals can contribute to the reduction of levels of an...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2020.105284
更新日期:2021-01-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/j.earlhumdev.2017.12.008
更新日期:2018-02-01 00:00:00
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journal_title:Early human development
pub_type: 杂志文章,评审
doi:10.1016/j.earlhumdev.2005.10.011
更新日期:2005-12-01 00:00:00
abstract::The world's literature has been scoured to obtain data on 492 examples of the fetal alcohol syndrome (FAS) in the Northern Hemisphere. The seasonally pattern of FAS birth prevalence rates is compared with the seasonality pattern of ethanol intakes to estimate the time-lag between them and hence the timing of ethanol d...
journal_title:Early human development
pub_type: 杂志文章
doi:10.1016/0378-3782(83)90065-8
更新日期:1983-07-01 00:00:00